Project description DEENESFRITPL Holistic integrated models will better predict potential undesired effects of nanomaterials Nanomaterials are revolutionising fields from composites and coatings to energy, biomedicine and optoelectronics. The unique and exotic properties exhibited by many materials at the nanoscale that are not exhibited by the same materials in bulk form have paved the way for unprecedented material and device functions. However, these very small sizes increase the materials' potential to access, settle in and affect living organisms during a product’s life cycle. The EU-funded NanoInformaTIX project is developing a multiscale modelling framework integrating numerous databases and models in one to optimise the assessment of exposure and toxicity associated with engineered nanomaterials. Show the project objective Hide the project objective Objective NanoInformaTIX aims to create a comprehensive, sustainable, multi-scale modelling framework for exposure and (eco)-toxicity of Engineered Nanomaterials (ENM) to facilitate cost-effective risk assessment, less reliant on animal testing, and to support the design of safer materials and products. Our approach integrates several relevant EU/US databases with validated nanoinformatics models covering: Materials, Exposure, Physiologically-Based Pharmacokinetics (PBPK), Quantitative-Structure-Activity Relations (QSAR) and Systems Biology modelling and in vitro/in vivo extrapolation to support the prediction of biological effects and exposure of ENM at various stages of their life cycle and product development. NanoInformaTIX will address grouping and read-across for risk assessment and safer product design. NanoInformaTIX will use existing curated data from several completed EU/US projects and from peer-reviewed literature to develop, extend the models and will also consider emerging data from ongoing projects for model validation following the OECD validation principles. This will take the NanoInformaTIX models from TLR4 to TLR6. The NanoInformaTIX modelling framework will be a web-based platform with a user-friendly interface tailored to the needs of different stakeholders (industry, regulators, academia and the civil society). To obtain optimal confidence in the use of the NanoInformaTIX modelling and database framework, all models will be described clearly using agreed standards terminology and implemented on harmonized standard operating protocols based on Good Modelling/Software Design practices. Their applicability domain will be clearly documented and referenced for full transparency and detailed user guidance for each will be provided. NanoInformaTIX will achieve considerable impact by providing the much -needed validated accessible data management modelling framework to predict human and environmental risks, to support the design of sustainable ENM and products. Fields of science natural sciencescomputer and information sciencessoftwarenatural sciencescomputer and information sciencesdatabasesmedical and health sciencesbasic medicinepharmacology and pharmacypharmacokineticssocial sciencespolitical sciencespolitical policiescivil societyengineering and technologynanotechnologynano-materials Keywords Engineered Nanomaterials Grouping Classifying Multi-scale Material Modelling Exposure PBPK QSAR Systems Biology Models Web-based platform Safe-by-Design Reduction of Animal Experiments Programme(s) H2020-EU.2.1.3. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials Main Programme H2020-EU.2.1.2. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies Topic(s) NMBP-14-2018 - Nanoinformatics: from materials models to predictive toxicology and ecotoxicology (RIA) Call for proposal H2020-NMBP-TO-IND-2018-2020 See other projects for this call Sub call H2020-NMBP-TO-IND-2018 Funding Scheme RIA - Research and Innovation action Coordinator AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Net EU contribution € 380 000,00 Address Calle serrano 117 28006 Madrid Spain See on map Region Comunidad de Madrid Comunidad de Madrid Madrid Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (36) Sort alphabetically Sort by Net EU contribution Expand all Collapse all INSTITUTE OF OCCUPATIONAL MEDICINE United Kingdom Net EU contribution € 223 360,00 Address Research avenue north, riccarton 45 EH14 4AP Edinburgh See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Scotland Eastern Scotland Edinburgh Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 EUROPEAN RESEARCH SERVICES GMBH Germany Net EU contribution € 168 000,00 Address Huefferstr. 5 48149 Muenster See on map Region Nordrhein-Westfalen Münster Münster, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 AARHUS UNIVERSITET Denmark Net EU contribution € 217 213,75 Address Nordre ringgade 1 8000 Aarhus c See on map Region Danmark Midtjylland Østjylland Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 BUNDESINSTITUT FUER RISIKOBEWERTUNG Germany Net EU contribution € 309 000,00 Address Max dohrn strasse 8-10 10589 Berlin See on map Region Berlin Berlin Berlin Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 GREENDECISION SRL Italy Net EU contribution € 101 812,50 Address Via torino 155/a 30172 Venezia See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Nord-Est Veneto Venezia Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 THOMAS MORE KEMPEN VZW Belgium Net EU contribution € 234 000,00 Address Kleinhoefstraat 4 2440 Geel See on map Region Vlaams Gewest Prov. Antwerpen Arr. Turnhout Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TEL AVIV UNIVERSITY Israel Net EU contribution € 255 000,00 Address Ramat aviv 69978 Tel aviv See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIWERSYTET GDANSKI Poland Net EU contribution € 219 450,00 Address Ul. bazynskiego 8 80309 Gdansk See on map Region Makroregion północny Pomorskie Trójmiejski Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN Ireland Net EU contribution € 178 175,00 Address Belfield 4 Dublin See on map Region Ireland Eastern and Midland Dublin Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITAT ROVIRA I VIRGILI Spain Net EU contribution € 233 993,75 Address Carrer de escorxador 43003 Tarragona See on map Region Este Cataluña Tarragona Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 IDEACONSULT LIMITED LIABILITY COMPANY Bulgaria Net EU contribution € 239 125,00 Address Angel kanchev 4 1000 Sofia See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Югозападна и Южна централна България Югозападен София (столица) Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 HELSINGIN YLIOPISTO Finland Net EU contribution € 300 875,00 Address Yliopistonkatu 3 00014 Helsingin yliopisto See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITEIT LEIDEN Netherlands Net EU contribution € 350 000,00 Address Rapenburg 70 2311 EZ Leiden See on map Region West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 SINTEF OCEAN AS Norway Net EU contribution € 170 000,00 Address Paul fjermstads veg 59 7052 Trondheim See on map Region Norge Trøndelag Trøndelag Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA Italy Net EU contribution € 188 750,00 Address Via cracovia 50 00133 Roma See on map Region Centro (IT) Lazio Roma Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ETHNICON METSOVION POLYTECHNION Greece Net EU contribution € 163 750,00 Address Heroon polytechniou 9 zographou campus 157 80 Athina See on map Region Αττική Aττική Κεντρικός Τομέας Αθηνών Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSIDADE DE AVEIRO Portugal Net EU contribution € 222 750,00 Address Campus universitário de santiago 3810-193 Aveiro See on map Region Continente Centro (PT) Região de Aveiro Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT Switzerland Net EU contribution € 233 617,50 Address Ueberlandstrasse 129 8600 Dubendorf See on map Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UPPINTECH OU Estonia Net EU contribution € 130 000,00 Address Parna tn 29-60 50604 Tartu See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Eesti Eesti Lõuna-Eesti Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 "NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS""" Greece Net EU contribution € 148 750,00 Address End of patriarchou grigoriou e and 27 neapoleos street 15341 Agia paraskevi See on map Region Αττική Aττική Βόρειος Τομέας Αθηνών Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 POLITECNICO DI TORINO Italy Net EU contribution € 234 375,00 Address Corso duca degli abruzzi 24 10129 Torino See on map Region Nord-Ovest Piemonte Torino Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 WARRANT HUB SPA Italy Net EU contribution € 233 000,00 Address Corso mazzini 11 42015 Correggio re See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Nord-Est Emilia-Romagna Reggio nell’Emilia Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TEMAS AG TECHNOLOGY AND MANAGEMENT SERVICES Participation ended Switzerland Net EU contribution € 88 195,18 Address Alpenstrasse 3 8152 Opfikon See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Schweiz/Suisse/Svizzera Zürich Zürich Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CONSIGLIO NAZIONALE DELLE RICERCHE Italy Net EU contribution € 159 363,75 Address Piazzale aldo moro 7 00185 Roma See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 DET NATIONALE FORSKNINGSCENTER FOR ARBEJDSMILJØ Denmark Net EU contribution € 114 750,00 Address Lerso parkalle 105 2100 Kobenhavn See on map Region Danmark Hovedstaden Byen København Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TYOTERVEYSLAITOS Finland Net EU contribution € 115 000,00 Address Topeliuksenkatu 41 b 00250 Helsinki See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 SWANSEA UNIVERSITY United Kingdom Net EU contribution € 284 945,00 Address Singleton park SA2 8PP Swansea See on map Region Wales West Wales and The Valleys Swansea Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITE D'AIX MARSEILLE France Net EU contribution € 100 000,00 Address Boulevard charles livon 58 le pharo 13284 Marseille See on map Region Provence-Alpes-Côte d’Azur Provence-Alpes-Côte d’Azur Bouches-du-Rhône Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 MINTEK South Africa Net EU contribution € 90 000,00 Address Malibongwe drive 200 2125 Randburg See on map Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ Germany Net EU contribution € 140 000,00 Address Permoserstrasse 15 04318 Leipzig See on map Region Sachsen Leipzig Leipzig Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 EAST EUROPEAN RESEARCH AND INNOVATION ENTERPRISE LTD Bulgaria Net EU contribution € 205 625,00 Address Mladost 2, 280a, entr. 3, floor 4, ap. 19 1799 Sofia See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Югозападна и Южна централна България Югозападен София (столица) Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY China Net EU contribution € 0,00 Address Zhong guan cun bei yi tiao 11 100190 Beijing See on map Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 818 750,00 NATIONAL CHENG KUNG UNIVERSITY Taiwan Net EU contribution € 0,00 Address University road 1 701 Tainan See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 148 965,00 SORBONNE UNIVERSITE France Net EU contribution € 120 000,00 Address 21 rue de l'ecole de medecine 75006 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITE CATHOLIQUE DE L'OUEST ASSOCIATION SAINT YVES France Net EU contribution € 80 125,00 Address Place andre leroy 3 49005 Angers See on map Region Pays de la Loire Pays de la Loire Maine-et-Loire Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TEMAS SOLUTIONS GMBH Switzerland Net EU contribution € 150 554,82 Address Laetteweg 5 5212 Hausen See on map Region Schweiz/Suisse/Svizzera Nordwestschweiz Aargau Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00