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Development and Implementation of a Sustainable Modelling Platform for NanoInformatics.

Objective

NanoInformaTIX aims to create a comprehensive, sustainable, multi-scale modelling framework for exposure and (eco)-toxicity of Engineered Nanomaterials (ENM) to facilitate cost-effective risk assessment, less reliant on animal testing, and to support the design of safer materials and products. Our approach integrates several relevant EU/US databases with validated nanoinformatics models covering: Materials, Exposure, Physiologically-Based Pharmacokinetics (PBPK), Quantitative-Structure-Activity Relations (QSAR) and Systems Biology modelling and in vitro/in vivo extrapolation to support the prediction of biological effects and exposure of ENM at various stages of their life cycle and product development. NanoInformaTIX will address grouping and read-across for risk assessment and safer product design. NanoInformaTIX will use existing curated data from several completed EU/US projects and from peer-reviewed literature to develop, extend the models and will also consider emerging data from ongoing projects for model validation following the OECD validation principles. This will take the NanoInformaTIX models from TLR4 to TLR6. The NanoInformaTIX modelling framework will be a web-based platform with a user-friendly interface tailored to the needs of different stakeholders (industry, regulators, academia and the civil society). To obtain optimal confidence in the use of the NanoInformaTIX modelling and database framework, all models will be described clearly using agreed standards terminology and implemented on harmonized standard operating protocols based on Good Modelling/Software Design practices. Their applicability domain will be clearly documented and referenced for full transparency and detailed user guidance for each will be provided. NanoInformaTIX will achieve considerable impact by providing the much -needed validated accessible data management modelling framework to predict human and environmental risks, to support the design of sustainable ENM and products.

Field of science

  • /social sciences/economics and business/economics/sustainable economy
  • /natural sciences/computer and information sciences/databases
  • /social sciences/political science/government systems/civil society

Call for proposal

H2020-NMBP-TO-IND-2018
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Address
Calle Serrano 117
28006 Madrid
Spain
Activity type
Research Organisations
EU contribution
€ 380 000

Participants (35)

INSTITUTE OF OCCUPATIONAL MEDICINE
United Kingdom
EU contribution
€ 223 360
Address
Research Avenue North, Riccarton 45
EH14 4AP Edinburgh
Activity type
Research Organisations
EUROPEAN RESEARCH SERVICES GMBH
Germany
EU contribution
€ 168 000
Address
Roentgenstrasse 19
48149 Muenster
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
AARHUS UNIVERSITET
Denmark
EU contribution
€ 217 213,75
Address
Nordre Ringgade 1
8000 Aarhus C
Activity type
Higher or Secondary Education Establishments
BUNDESINSTITUT FUER RISIKOBEWERTUNG
Germany
EU contribution
€ 309 000
Address
Max Dohrn Strasse 8-10
10589 Berlin
Activity type
Research Organisations
GREENDECISION SRL
Italy
EU contribution
€ 101 812,50
Address
Via Torino 155/A
30172 Venezia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THOMAS MORE KEMPEN VZW
Belgium
EU contribution
€ 234 000
Address
Kleinhoefstraat 4
2440 Geel
Activity type
Higher or Secondary Education Establishments
TEL AVIV UNIVERSITY
Israel
EU contribution
€ 255 000
Address
Ramat Aviv
69978 Tel Aviv
Activity type
Higher or Secondary Education Establishments
UNIWERSYTET GDANSKI
Poland
EU contribution
€ 219 450
Address
Ul. Bazynskiego 8
80309 Gdansk
Activity type
Higher or Secondary Education Establishments
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Ireland
EU contribution
€ 178 175
Address
Belfield
4 Dublin
Activity type
Higher or Secondary Education Establishments
UNIVERSITAT ROVIRA I VIRGILI
Spain
EU contribution
€ 233 993,75
Address
Carrer De Escorxador
43003 Tarragona
Activity type
Higher or Secondary Education Establishments
IDEACONSULT LIMITED LIABILITY COMPANY
Bulgaria
EU contribution
€ 239 125
Address
Angel Kanchev 4
1000 Sofia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
HELSINGIN YLIOPISTO
Finland
EU contribution
€ 300 875
Address
Yliopistonkatu 3
00014 Helsingin Yliopisto
Activity type
Higher or Secondary Education Establishments
UNIVERSITEIT LEIDEN
Netherlands
EU contribution
€ 350 000
Address
Rapenburg 70
2311 EZ Leiden
Activity type
Higher or Secondary Education Establishments
SINTEF OCEAN AS
Norway
EU contribution
€ 170 000
Address
Otto Nielsens Veg 10
7052 Trondheim
Activity type
Other
UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA
Italy
EU contribution
€ 188 750
Address
Via Cracovia 50
00133 Roma
Activity type
Higher or Secondary Education Establishments
NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA
Greece
EU contribution
€ 163 750
Address
Heroon Polytechniou 9 Zographou Campus
15780 Athina
Activity type
Higher or Secondary Education Establishments
UNIVERSIDADE DE AVEIRO
Portugal
EU contribution
€ 222 750
Address
Campus Universitário De Santiago
3810-193 Aveiro
Activity type
Higher or Secondary Education Establishments
EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT
Switzerland
EU contribution
€ 233 617,50
Address
Ueberlandstrasse 129
8600 Dubendorf
Activity type
Higher or Secondary Education Establishments
UPPINTECH OU
Estonia
EU contribution
€ 130 000
Address
Parna Tn 29-60
50604 Tartu
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
"NATIONAL CENTER FOR SCIENTIFIC RESEARCH ""DEMOKRITOS"""
Greece
EU contribution
€ 148 750
Address
End Of Patriarchou Grigoriou E And 27 Neapoleos Street
15341 Agia Paraskevi
Activity type
Research Organisations
POLITECNICO DI TORINO
Italy
EU contribution
€ 234 375
Address
Corso Duca Degli Abruzzi 24
10129 Torino
Activity type
Higher or Secondary Education Establishments
WARRANT HUB SPA
Italy
EU contribution
€ 233 000
Address
Corso Mazzini 11
42015 Correggio Re
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
TEMAS AG TECHNOLOGY AND MANAGEMENT SERVICES

Participation ended

Switzerland
EU contribution
€ 238 750
Address
Alpenstrasse 3
8152 Opfikon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
EU contribution
€ 159 363,75
Address
Piazzale Aldo Moro 7
00185 Roma
Activity type
Research Organisations
DET NATIONALE FORSKNINGSCENTER FORARBEJDSMILJO
Denmark
EU contribution
€ 114 750
Address
Lerso Parkalle 105
2100 Kobenhavn
Activity type
Research Organisations
TYOTERVEYSLAITOS
Finland
EU contribution
€ 115 000
Address
Topeliuksenkatu 41 B
00250 Helsinki
Activity type
Research Organisations
SWANSEA UNIVERSITY
United Kingdom
EU contribution
€ 284 945
Address
Singleton Park
SA2 8PP Swansea
Activity type
Higher or Secondary Education Establishments
UNIVERSITE D'AIX MARSEILLE
France
EU contribution
€ 100 000
Address
Boulevard Charles Livon 58
13284 Marseille
Activity type
Higher or Secondary Education Establishments
MINTEK
South Africa
EU contribution
€ 90 000
Address
Malibongwe Drive 200
2125 Randburg
Activity type
Research Organisations
HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ
Germany
EU contribution
€ 140 000
Address
Permoserstrasse 15
04318 Leipzig
Activity type
Other
EAST EUROPEAN RESEARCH AND INNOVATION ENTERPRISE LTD
Bulgaria
EU contribution
€ 205 625
Address
Mladost 2, 280A, Entr. 3, Floor 4, Ap. 19
1799 Sofia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY, CHINA
China
EU contribution
€ 0
Address
Zhong Guan Cun Bei Yi Tiao 11
100190 Beijing
Activity type
Research Organisations
NATIONAL CHENG KUNG UNIVERSITY
Taiwan
EU contribution
€ 0
Address
University Road 1
701 Tainan
Activity type
Higher or Secondary Education Establishments
SORBONNE UNIVERSITE
France
EU contribution
€ 120 000
Address
21 Rue De L'ecole De Medecine
75006 Paris
Activity type
Higher or Secondary Education Establishments
UNIVERSITE CATHOLIQUE DE L'OUEST ASSOCIATION SAINT YVES
France
EU contribution
€ 80 125
Address
Place Andre Leroy 3
49005 Angers
Activity type
Research Organisations