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Innovative Nanoinformatics models and tools: towards a Solid, verified and Integrated Approach to Predictive (eco)Toxicology (NanoSolveIT)

Deliverables

Collection of system requirements and specifications

Collection of system requirements and specifications

Completion of existing omics data preprocessing and transfer of data to WP1

Completion of existing omics data preprocessing and transfer of data to WP1

An ontology-backed data completeness standard for curation use

An ontology-backed data completeness standard for curation use

Architecture of NanoSolveIT e-platform and API specifications

Architecture of NanoSolveIT e-platform and API specifications

Initial inventory of MoAs, MIEs and predictive NMs descriptors

Initial inventory of MoAs, MIEs and predictive NMs descriptors

Initial data management plan (DMP) as part of the open data pilot

Initial data management plan (DMP) as part of the open data pilot

Searching for OpenAIRE data...

Publications

Risk Governance of Emerging Technologies Demonstrated in Terms of its Applicability to Nanomaterials

Author(s): Panagiotis Isigonis, Antreas Afantitis, Dalila Antunes, Alena Bartonova, Ali Beitollahi, Nils Bohmer, Evert Bouman, Qasim Chaudhry, Mihaela Roxana Cimpan, Emil Cimpan, Shareen Doak, Damien Dupin, Doreen Fedrigo, Valérie Fessard, Maciej Gromelski, Arno C. Gutleb, Sabina Halappanavar, Peter Hoet, Nina Jeliazkova, Stéphane Jomini, Sabine Lindner, Igor Linkov, Eleonora Marta Longhin, Iseult Lynch, I
Published in: Small, Issue 16/36, 2020, Page(s) 2003303, ISSN 1613-6810
DOI: 10.1002/smll.202003303

Current Approaches and Techniques in Physiologically Based Pharmacokinetic (PBPK) Modelling of Nanomaterials

Author(s): Wells Utembe, Harvey Clewell, Natasha Sanabria, Philip Doganis, Mary Gulumian
Published in: Nanomaterials, Issue 10/7, 2020, Page(s) 1267, ISSN 2079-4991
DOI: 10.3390/nano10071267

Mass Cytometry and Single‐Cell RNA‐seq Profiling of the Heterogeneity in Human Peripheral Blood Mononuclear Cells Interacting with Silver Nanoparticles

Author(s): My Kieu Ha, Sook Jin Kwon, Jang‐Sik Choi, Nguyen Thanh Nguyen, Jaewoo Song, Yangsoon Lee, Young‐Eun Kim, Incheol Shin, Jin‐Wu Nam, Tae Hyun Yoon
Published in: Small, Issue 16/21, 2020, Page(s) 1907674, ISSN 1613-6810
DOI: 10.1002/smll.201907674

Development of Deep Learning Models for Predicting the Effects of Exposure to Engineered Nanomaterials on Daphnia magna

Author(s): Pantelis Karatzas, Georgia Melagraki, Laura‐Jayne A. Ellis, Iseult Lynch, Dimitra‐Danai Varsou, Antreas Afantitis, Andreas Tsoumanis, Philip Doganis, Haralambos Sarimveis
Published in: Small, Issue 16/36, 2020, Page(s) 2001080, ISSN 1613-6810
DOI: 10.1002/smll.202001080

TinderMIX: Time-dose integrated modelling of toxicogenomics data

Author(s): Angela Serra, Michele Fratello, Giusy del Giudice, Laura Aliisa Saarimäki, Michelangelo Paci, Antonio Federico, Dario Greco
Published in: GigaScience, Issue 9/5, 2020, ISSN 2047-217X
DOI: 10.1093/gigascience/giaa055

NanoSolveIT Project: Driving nanoinformatics research to develop innovative and integrated tools for in silico nanosafety assessment

Author(s): Antreas Afantitis, Georgia Melagraki, Panagiotis Isigonis, Andreas Tsoumanis, Dimitra Danai Varsou, Eugenia Valsami-Jones, Anastasios Papadiamantis, Laura-Jayne A. Ellis, Haralambos Sarimveis, Philip Doganis, Pantelis Karatzas, Periklis Tsiros, Irene Liampa, Vladimir Lobaskin, Dario Greco, Angela Serra, Pia Anneli Sofia Kinaret, Laura Aliisa Saarimäki, Roland Grafström, Pekka Kohonen, Penny Nyma
Published in: Computational and Structural Biotechnology Journal, Issue 18, 2020, Page(s) 583-602, ISSN 2001-0370
DOI: 10.1016/j.csbj.2020.02.023

Transcriptomics in Toxicogenomics, Part III: Data Modelling for Risk Assessment

Author(s): Angela Serra, Michele Fratello, Luca Cattelani, Irene Liampa, Georgia Melagraki, Pekka Kohonen, Penny Nymark, Antonio Federico, Pia Anneli Sofia Kinaret, Karolina Jagiello, My Kieu Ha, Jang-Sik Choi, Natasha Sanabria, Mary Gulumian, Tomasz Puzyn, Tae-Hyun Yoon, Haralambos Sarimveis, Roland Grafström, Antreas Afantitis, Dario Greco
Published in: Nanomaterials, Issue 10/4, 2020, Page(s) 708, ISSN 2079-4991
DOI: 10.3390/nano10040708

Zeta‐Potential Read‐Across Model Utilizing Nanodescriptors Extracted via the NanoXtract Image Analysis Tool Available on the Enalos Nanoinformatics Cloud Platform

Author(s): Dimitra‐Danai Varsou, Antreas Afantitis, Andreas Tsoumanis, Anastasios Papadiamantis, Eugenia Valsami‐Jones, Iseult Lynch, Georgia Melagraki
Published in: Small, Issue 16/21, 2020, Page(s) 1906588, ISSN 1613-6810
DOI: 10.1002/smll.201906588

Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects

Author(s): Pia Anneli Sofia Kinaret, Angela Serra, Antonio Federico, Pekka Kohonen, Penny Nymark, Irene Liampa, My Kieu Ha, Jang-Sik Choi, Karolina Jagiello, Natasha Sanabria, Georgia Melagraki, Luca Cattelani, Michele Fratello, Haralambos Sarimveis, Antreas Afantitis, Tae-Hyun Yoon, Mary Gulumian, Roland Grafström, Tomasz Puzyn, Dario Greco
Published in: Nanomaterials, Issue 10/4, 2020, Page(s) 750, ISSN 2079-4991
DOI: 10.3390/nano10040750

Toward Rigorous Materials Production: New Approach Methodologies Have Extensive Potential to Improve Current Safety Assessment Practices

Author(s): Penny Nymark, Martine Bakker, Susan Dekkers, Remy Franken, Wouter Fransman, Amaia García‐Bilbao, Dario Greco, Mary Gulumian, Niels Hadrup, Sabina Halappanavar, Vesa Hongisto, Karin Sørig Hougaard, Keld Alstrup Jensen, Pekka Kohonen, Antti Joonas Koivisto, Miikka Dal Maso, Thies Oosterwijk, Mikko Poikkimäki, Isabel Rodriguez‐Llopis, Rob Stierum, Jorid Birkelund Sørli, Roland Grafström
Published in: Small, Issue 16/6, 2020, Page(s) 1904749, ISSN 1613-6810
DOI: 10.1002/smll.201904749

Exposure medium and particle ageing moderate the toxicological effects of nanomaterials to Daphnia magna over multiple generations: a case for standard test review?

Author(s): Laura-Jayne A. Ellis, Eugenia Valsami-Jones, Iseult Lynch
Published in: Environmental Science: Nano, Issue 7/4, 2020, Page(s) 1136-1149, ISSN 2051-8153
DOI: 10.1039/d0en00049c

Advanced in silico characterization of nanomaterials for nanoparticle toxicology

Author(s): Rouse, Ian; Power, David; Brandt, Erik G.; Schneemilch, Matthew; Kotsis, Konstantinos; Quirke, Nick; Lyubartsev, Alexander P.; Lobaskin, Vladimir
Published in: arXiv, Issue 2, 2020