Site-specific Ultrasensitive Magnetic resonance of Mixtures for Isotopic Tracking

Project Information

SUMMIT

Grant agreement ID: 814747

DOI 10.3030/814747

EC signature date 6 February 2019

Start date 1 October 2019

End date 30 September 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 999 768,00

EU contribution € 1 999 768,00

Coordinated by

NANTES UNIVERSITE
France

Publications

Peer reviewed articles (17)

Hyperpolarized ¹³C NMR Spectroscopy of Urine Samples at Natural Abundance by Quantitative Dissolution Dynamic Nuclear Polarization

Author(s): Victor Ribay; Arnab Dey; Benoît Charrier; Clément Praud; Joris Mandral; Jean‐Nicolas Dumez; Marine P. M. Letertre; Patrick Giraudeau
Published in: Crossref, Issue 6, 2023, Page(s) e202302110, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202302110

Solution‐State 2D NMR Spectroscopy of Mixtures HyperpolarizedUsing Optically Polarized Crystals

Author(s): Anna J. Parker; Arnab Dey; Mohammad Usman Qureshi; Jakob M. Steiner; John W. Blanchard; Jochen Scheuer; Nikolas Tomek; Stephan Knecht; Felix Josten; Christoph Müller; Patrick Hautle; Ilai Schwartz; Patrick Giraudeau; Tim R. Eichhorn; Jean‐Nicolas Dumez
Published in: Crossref, Issue 7, 2023, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ange.202312302

Ultrafast 2D NMR for the analysis of complex mixtures

Author(s): Célia Lhoste, Benjamin Lorandel, Clément Praud, Achille Marchand, Rituraj Mishra, Arnab Dey, Aurélie Bernard, Jean-Nicolas Dumez, Patrick Giraudeau
Published in: Progress in Nuclear Magnetic Resonance Spectroscopy, Issue 130-131, 2022, Page(s) 1-44, ISSN 0079-6565
Publisher: Elsevier BV
DOI: 10.1016/j.pnmrs.2022.01.002

Scaling-up metabolomics: Current state and perspectives

Author(s): Ghina Hajjar; Millena C. Barros Santos; Justine Bertrand-Michel; Cécile Canlet; Florence Castelli; Nicolas Creusot; Sylvain Dechaumet; Binta Diémé; Franck Giacomoni; Patrick Giraudeau; Yann Guitton; Etienne Thévenot; Marie Tremblay-Franco; Christophe Junot; Fabien Jourdan; François Fenaille; Blandine Comte; Pierre Pétriacq; Estelle Pujos-Guillot
Published in: EISSN: 0165-9936, Issue 7, 2023, ISSN 0165-9936
Publisher: Elsevier BV
DOI: 10.1016/j.trac.2023.117225

In-line Multidimensional NMR Monitoring of Photochemical Flow Reactions

Author(s): Margherita Bazzoni, Célia Lhoste, Justine Bonnet, Kouakou Eric Konan, Aurélie Bernard, Patrick Giraudeau, François-Xavier Felpin, Jean-Nicolas Dumez
Published in: Chemistry: a European Journal, 2023, Page(s) e202203240, ISSN 1521-3765
Publisher: John Wiley and Sons
DOI: 10.1002/chem.202203240

NMR metabolite quantification of a synthetic urine sample: an inter-laboratory comparison of processing workflows

Author(s): Cécile Canlet; Catherine Deborde; Edern Cahoreau; Grégory Da Costa; Roselyne Gautier; Daniel Jacob; Cyril Jousse; Mélia Lacaze; Inès Le Mao; Estelle Martineau; Lindsay Peyriga; Tristan Richard; Virginie Silvestre; Mounir Traïkia; Annick Moing; Patrick Giraudeau
Published in: ISSN: 1573-3882, Issue 2, 2023, ISSN 1573-3890
Publisher: Springer
DOI: 10.1007/s11306-023-02028-4

Hyperpolarized ¹H and ¹³C NMR Spectroscopy in a Single Experiment for Metabolomics

Author(s): Arnab Dey; Benoît Charrier; Victor Ribay; Jean-Nicolas Dumez; Patrick Giraudeau
Published in: Crossref, Issue 4, 2023, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.3c02614

Hyperpolarized NMR metabolomics

Author(s): Victor Ribay, Clément Praud, Marine P. M. Letertre, Jean-Nicolas Dumez, Patrick Giraudeau
Published in: Current opinion in chemical biology, 2023, Page(s) 102307, ISSN 1879-0402
Publisher: Elsevier
DOI: 10.1016/j.cbpa.2023.102307

Ultrafast 2D 1H–1H NMR spectroscopy of DNP-hyperpolarised substrates for the analysis of mixtures

Author(s): Kawarpal Singh; Corentin Jacquemmoz; Patrick Giraudeau; Lucio Frydman; Jean-Nicolas Dumez
Published in: Chemical Communications, 2021, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1cc03079e

Broadband ultrafast 2D NMR spectroscopy for online monitoring in continuous flow

Author(s): Célia Lhoste; Margherita Bazzoni; Justine Bonnet; Aurélie Bernard; François-Xavier Felpin; Patrick Giraudeau; Jean-Nicolas Dumez
Published in: Analyst, Issue 9, 2023, ISSN 0003-2654
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3an01165h

Optimization of heteronuclear ultrafast 2D NMR for the study of complex mixtures hyperpolarized by dynamic nuclear polarization

Author(s): Clément Praud; Victor Ribay; Arnab Dey; Benoît Charrier; Joris Mandral; Jonathan Farjon; Jean-Nicolas Dumez; Patrick Giraudeau
Published in: Crossref, Issue 6, 2023, ISSN 1759-9679
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3ay01681a

Quantitative NMR spectroscopy of complex mixtures

Author(s): Patrick Giraudeau
Published in: Chemical Communications, 2023, Page(s) 6627-6642, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3cc01455j

Nuclear Magnetic Resonance Spectroscopy in Clinical Metabolomics and Personalized Medicine: Current Challenges and Perspectives

Author(s): Marine Letertre, Patrick Giraudeau, Pascal de Tullio
Published in: Frontiers in Molecular Biosciences - Metabolomics, 2021, ISSN 2296-889X
Publisher: Frontiers
DOI: 10.3389/fmolb.2021.698337

Fine optimization of a dissolution dynamic nuclear polarization experimental setting for 13C NMR of metabolic samples

Author(s): Arnab Dey, Benoît Charrier, Karine Lemaitre, Victor Ribay, Dmitry Eshchenko, Marc Schnell, Roberto Melzi, Quentin Stern, Samuel F. Cousin, James G. Kempf, Sami Jannin, Jean-Nicolas Dumez, and Patrick Giraudeau
Published in: Magnetic Resonance, Issue 26990016, 2022, ISSN 2699-0016
Publisher: Copernicus
DOI: 10.5194/mr-3-183-2022

Combined Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry Approaches for Metabolomics

Author(s): Marine P. M. Letertre, Gaud Dervilly, Patrick Giraudeau
Published in: Analytical Chemistry, Issue 93/1, 2021, Page(s) 500-518, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.0c04371

NMR-based metabolomics and fluxomics: developments and future prospects

Author(s): Patrick Giraudeau
Published in: The Analyst, Issue 145/7, 2020, Page(s) 2457-2472, ISSN 0003-2654
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0an00142b

Hyperpolarized NMR Metabolomics at Natural 13 C Abundance

Author(s): Arnab Dey, Benoît Charrier, Estelle Martineau, Catherine Deborde, Elodie Gandriau, Annick Moing, Daniel Jacob, Dmitry Eshchenko, Marc Schnell, Roberto Melzi, Dennis Kurzbach, Morgan Ceillier, Quentin Chappuis, Samuel F. Cousin, James G. Kempf, Sami Jannin, Jean-Nicolas Dumez, Patrick Giraudeau
Published in: Analytical Chemistry, Issue 92/22, 2020, Page(s) 14867-14871, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.0c03510

Book chapters (2)

Fast 2D NMR for metabolomics

Author(s): Clément Praud, Marine P.M. Letertre, Arnab Dey, Jean-Nicolas Dumez, Patrick Giraudeau
Published in: Fast 2D solution-state NMR, 2023, ISBN 978-1-83916-400-2
Publisher: Royal Society of Chemistry
DOI: 10.1039/bk9781839168062-00377

Fast 2D NMR for Reaction and Process Monitoring

Author(s): Margherita Bazzoni, Benjamin Lorandel, Célia Lhoste, Patrick Giraudeau, Jean-Nicolas Dumez
Published in: Fast 2D solution state NMR, 2023, ISBN 978-1-83916-400-2
Publisher: Royal Society of Chemistry
DOI: 10.1039/bk9781839168062-00251