Collaboration for innovation: Establishment of a pan-nematode drug development platform

Project Information

HELP

Grant agreement ID: 815628

DOI

10.3030/815628

Project closed

EC signature date 30 April 2019

Start date 1 September 2019

End date 28 February 2026

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost

No data

EU contribution

€ 8 713 395,42

Coordinated by

SCHWEIZERISCHES TROPEN UND PUBLIC HEALTH INSTITUT
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (1)

HELP Homepage

Website (link and screenshots).

Publications

Peer reviewed articles (6)

Repurposing Oxfendazole for Onchocerciasis: Population Pharmacokinetics of a Tablet Formulation in Healthy African Adults

Author(s): Frauke Assmus, Ayorinde Adehin, Richard M. Hoglund, Gloria Nyaulingo, Hussein Mbarak, Said Jongo, Eveline Ackermann, Elisabeth Reus, Jennifer Keiser, Fabiana Barreira Da Silva Rocha, Sabine Specht, Ivan Scandale, Joel Tarning
Published in: CPT: Pharmacometrics & Systems Pharmacology, Issue 15, 2026, ISSN 2163-8306
Publisher: Nature Publishing Group
DOI: 10.1002/psp4.70189

Unbalanced Arginine pathway and altered maturation of pleural macrophages in Th2-deficient mice during Litomosoides sigmodontis filarial infection

Author(s): Estelle Remion, Joséphine Gal, Soraya Chaouch, Jules Rodrigues, Nathaly Lhermitte-Vallarino, Joy Alonso, Linda Kohl, Marc P. Hübner, Frédéric Fercoq, Coralie Martin
Published in: Frontiers in Immunology, Issue 13, 2022, ISSN 1664-3224
Publisher: Frontiers Media SA
DOI: 10.3389/fimmu.2022.866373

<i>Wolbachia</i> springs eternal: symbiosis in Collembola is associated with host ecology

Author(s): Jules Rodrigues, Emilie Lefoulon, Laurent Gavotte, Marco Perillat-Sanguinet, Benjamin Makepeace, Coralie Martin, Cyrille A. D'Haese
Published in: Royal Society Open Science, Issue 10, 2023, ISSN 2054-5703
Publisher: The Royal Society
DOI: 10.1098/rsos.230288

Pharmacokinetics, safety, and tolerability of an oxfendazole tablet formulation: a phase 1, randomized, placebo-controlled trial in healthy African volunteers

Author(s): Said Jongo, Eveline Ackermann, Gloria Nyaulingo, Hussein Mbaraka, Elisabeth Reus, Silvia Cicconi, Meera Saxena, Kamaka Kassim, Anneth Tumbo, Mohammed Ally Rashid, Stephen Robinson, Mathieu Louis, Vijay Satam, Fabiana Barreira Da Silva Rocha, Ivan Scandale, Frauke Assmus, Jennifer Keiser, Sabine Specht
Published in: Antimicrobial Agents and Chemotherapy, Issue 70, 2026, ISSN 0066-4804
Publisher: American Society for Microbiology
DOI: 10.1128/aac.01315-25

Preclinical and Clinical Characteristics of the Trichuricidal Drug Oxantel Pamoate and Clinical Development Plans: A Review

Author(s): Marta S. Palmeirim, Sabine Specht, Ivan Scandale, Irene Gander-Meisterernst, Monika Chabicovsky, Jennifer Keiser
Published in: Drugs, Issue 81/8, 2021, Page(s) 907-921, ISSN 0012-6667
Publisher: Adis International Ltd.
DOI: 10.1007/s40265-021-01505-1

Microfilaria-dependent thoracic pathology associated with eosinophilic and fibrotic polyps in filaria-infected rodents

Author(s): Frédéric Fercoq, Estelle Remion, Nathaly Vallarino-Lhermitte, Joy Alonso, Lisy Raveendran, Colin Nixon, John Le Quesne, Leo M. Carlin, Coralie Martin
Published in: Parasites &amp; Vectors, Issue 13, 2022, ISSN 1756-3305
Publisher: BioMed Central
DOI: 10.1186/s13071-020-04428-0