Collaboration for innovation: Establishment of a pan-nematode drug development platform

Informazioni relative al progetto

HELP

ID dell’accordo di sovvenzione: 815628

DOI

10.3030/815628

Progetto chiuso

Data della firma CE 30 Aprile 2019

Data di avvio 1 Settembre 2019

Data di completamento 28 Febbraio 2026

Finanziato da

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Costo totale

Nessun dato

Contributo UE

€ 8 713 395,42

Coordinato da

SCHWEIZERISCHES TROPEN UND PUBLIC HEALTH INSTITUT
Switzerland

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Websites, patent fillings, videos etc. (1)

HELP Homepage

Website (link and screenshots).

Documents, reports (2)

Report on dissemination and exploitation activities during HELP

Final report on dissemination and exploitation activities during HELP.

Communication report 4

Final Report on completed communication activities during HELP.

Pubblicazioni

Peer reviewed articles (6)

Repurposing Oxfendazole for Onchocerciasis: Population Pharmacokinetics of a Tablet Formulation in Healthy African Adults

Autori: Frauke Assmus, Ayorinde Adehin, Richard M. Hoglund, Gloria Nyaulingo, Hussein Mbarak, Said Jongo, Eveline Ackermann, Elisabeth Reus, Jennifer Keiser, Fabiana Barreira Da Silva Rocha, Sabine Specht, Ivan Scandale, Joel Tarning
Pubblicato in: CPT: Pharmacometrics & Systems Pharmacology, Numero 15, 2026, ISSN 2163-8306
Editore: Nature Publishing Group
DOI: 10.1002/psp4.70189

Unbalanced Arginine pathway and altered maturation of pleural macrophages in Th2-deficient mice during Litomosoides sigmodontis filarial infection

Autori: Estelle Remion, Joséphine Gal, Soraya Chaouch, Jules Rodrigues, Nathaly Lhermitte-Vallarino, Joy Alonso, Linda Kohl, Marc P. Hübner, Frédéric Fercoq, Coralie Martin
Pubblicato in: Frontiers in Immunology, Numero 13, 2022, ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/fimmu.2022.866373

<i>Wolbachia</i> springs eternal: symbiosis in Collembola is associated with host ecology

Autori: Jules Rodrigues, Emilie Lefoulon, Laurent Gavotte, Marco Perillat-Sanguinet, Benjamin Makepeace, Coralie Martin, Cyrille A. D'Haese
Pubblicato in: Royal Society Open Science, Numero 10, 2023, ISSN 2054-5703
Editore: The Royal Society
DOI: 10.1098/rsos.230288

Pharmacokinetics, safety, and tolerability of an oxfendazole tablet formulation: a phase 1, randomized, placebo-controlled trial in healthy African volunteers

Autori: Said Jongo, Eveline Ackermann, Gloria Nyaulingo, Hussein Mbaraka, Elisabeth Reus, Silvia Cicconi, Meera Saxena, Kamaka Kassim, Anneth Tumbo, Mohammed Ally Rashid, Stephen Robinson, Mathieu Louis, Vijay Satam, Fabiana Barreira Da Silva Rocha, Ivan Scandale, Frauke Assmus, Jennifer Keiser, Sabine Specht
Pubblicato in: Antimicrobial Agents and Chemotherapy, Numero 70, 2026, ISSN 0066-4804
Editore: American Society for Microbiology
DOI: 10.1128/aac.01315-25

Preclinical and Clinical Characteristics of the Trichuricidal Drug Oxantel Pamoate and Clinical Development Plans: A Review

Autori: Marta S. Palmeirim, Sabine Specht, Ivan Scandale, Irene Gander-Meisterernst, Monika Chabicovsky, Jennifer Keiser
Pubblicato in: Drugs, Numero 81/8, 2021, Pagina/e 907-921, ISSN 0012-6667
Editore: Adis International Ltd.
DOI: 10.1007/s40265-021-01505-1

Microfilaria-dependent thoracic pathology associated with eosinophilic and fibrotic polyps in filaria-infected rodents

Autori: Frédéric Fercoq, Estelle Remion, Nathaly Vallarino-Lhermitte, Joy Alonso, Lisy Raveendran, Colin Nixon, John Le Quesne, Leo M. Carlin, Coralie Martin
Pubblicato in: Parasites &amp; Vectors, Numero 13, 2022, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.1186/s13071-020-04428-0