Microbiota-host interactions for integrative metabolic health reprogramming

Project Information

Healthybiota

Grant agreement ID: 815962

DOI

10.3030/815962

Project closed

EC signature date 28 May 2019

Start date 1 June 2019

End date 31 May 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 999 999,00

EU contribution

€ 1 999 999,00

Coordinated by

UNIVERSITE DE GENEVE
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Metataxonomic and Metabolic Impact of Fecal Microbiota Transplantation From Patients With Pancreatic Cancer Into Germ-Free Mice: A Pilot Study

Author(s): Laurence Genton, Vladimir Lazarevic, Ozren Stojanovic, Martina Spiljar, Souad Djaafar, Thibaud Koessler, Valérie Dutoit, Nadia Gaïa, Julie Mareschal, Andrew James Macpherson, Francois Herrmann, Mirko Trajkovski, Jacques Schrenzel
Published in: Frontiers in Cellular and Infection Microbiology, Issue 11, 2021, ISSN 2235-2988
Publisher: Frontiers Media S. A.
DOI: 10.3389/fcimb.2021.752889

AMPK Profiling in Rodent and Human Pancreatic Beta-Cells under Nutrient-Rich Metabolic Stress

Author(s): Thierry Brun, Cecilia Jiménez-Sánchez, Jesper Grud Skat Madsen, Noushin Hadadi, Dominique Duhamel, Clarissa Bartley, Lucie Oberhauser, Mirko Trajkovski, Susanne Mandrup, Pierre Maechler
Published in: International Journal of Molecular Sciences, Issue 21/11, 2020, Page(s) 3982, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21113982

ATLAS: a Snakemake workflow for assembly, annotation, and genomic binning of metagenome sequence data

Author(s): Silas Kieser, Joseph Brown, Evgeny M. Zdobnov, Mirko Trajkovski, Lee Ann McCue
Published in: BMC Bioinformatics, Issue 21/1, 2020, ISSN 1471-2105
Publisher: BioMed Central
DOI: 10.1186/s12859-020-03585-4

Critical Assessment of Metagenome Interpretation: the second round of challenges

Author(s): Fernando Meyer, Adrian Fritz, Zhi-Luo Deng, David Koslicki, Till Robin Lesker, Alexey Gurevich, Gary Robertson, Mohammed Alser, Dmitry Antipov, Francesco Beghini, Denis Bertrand, Jaqueline J Brito, C Titus Brown, Jan Buchmann, Aydin Buluç , Bo Chen, Rayan Chikhi, Philip T L C Clausen, Alexandru Cristian, Piotr Wojciech Dabrowski, Aaron E Darling, Rob Egan, Eleazar Eskin, Evangelos Georganas, Euge
Published in: Nature Methods, Issue 19(4), 2022, Page(s) 429–440, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-022-01431-4

Warmth Prevents Bone Loss Through the Gut Microbiota

Author(s): Claire Chevalier, Silas Kieser, Melis Çolakoğlu, Noushin Hadadi, Julia Brun, Dorothée Rigo, Nicolas Suárez-Zamorano, Martina Spiljar, Salvatore Fabbiano, Björn Busse, Julijana Ivanišević, Andrew Macpherson, Nicolas Bonnet, Mirko Trajkovski
Published in: Cell Metabolism, Issue 32/4, 2020, Page(s) 575-590.e7, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2020.08.012

Primary mouse osteoblast and osteoclast culturing and analysis

Author(s): Claire Chevalier, Melis Çolakoğlu, Julia Brun, Cyril Thouverey, Nicolas Bonnet, Serge Ferrari, Mirko Trajkovski
Published in: STAR Protocols, Issue 2/2, 2021, Page(s) 100452, ISSN 2666-1667
Publisher: Elsevier
DOI: 10.1016/j.xpro.2021.100452

Cold exposure protects from neuroinflammation through immunologic reprogramming

Author(s): Martina Spiljar, Karin Steinbach, Dorothée Rigo, Nicolas Suárez-Zamorano, Ingrid Wagner, Noushin Hadadi, Ilena Vincenti, Nicolas Page, Bogna Klimek, Mary-Aude Rochat, Mario Kreutzfeldt, Claire Chevalier, Ozren Stojanović, Olivia Bejuy, Didier Colin, Matthias Mack, Dilay Cansever, Melanie Greter, Doron Merkler, Mirko Trajkovski
Published in: Cell Metabolism, Issue 33/11, 2021, Page(s) 2231-2246.e8, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2021.10.002

Comparative multi-tissue profiling reveals extensive tissue-specificity in transcriptome reprogramming during thermal adaptation

Author(s): Noushin Hadadi, Martina Spiljar, Karin Steinbach, Melis Çolakoğlu, Claire Chevalier, Gabriela Salinas, Doron Merkler, Mirko Trajkovski
Published in: eLife, Issue 17;11, 2022, Page(s) e78556, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.78556

Intestinal microbiota as a route for micronutrient bioavailability

Author(s): Noushin Hadadi, Vincent Berweiler, Haiping Wang, Mirko Trajkovski
Published in: Current Opinion in Endocrine and Metabolic Research, Issue 20, 2021, Page(s) 100285, ISSN 2451-9650
Publisher: Elsevier
DOI: 10.1016/j.coemr.2021.100285

Dietary excess regulates absorption and surface of gut epithelium through intestinal PPARα

Author(s): Ozren Stojanović, Jordi Altirriba, Dorothée Rigo, Martina Spiljar, Emilien Evrard, Benedek Roska, Salvatore Fabbiano, Nicola Zamboni, Pierre Maechler, Françoise Rohner-Jeanrenaud, Mirko Trajkovski
Published in: Nature Communications, Issue 12(1):7031, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-27133-7

Comprehensive mouse microbiota genome catalog reveals major difference to its human counterpart

Author(s): Silas Kieser; Evgeny M. Zdobnov; Mirko Trajkovski
Published in: PLoS computational biology, Vol. 18, No 3 (2022) P. e1009947, Issue 2, 2022, ISSN 1553-7358
Publisher: PLoS
DOI: 10.1371/journal.pcbi.1009947

Non-peer reviewed articles (1)

Bacteriophage Prevents Alcoholic Liver Disease

Author(s): Melis Çolakoğlu, Jing Xue, Mirko Trajkovski
Published in: Cell, Issue 180/2, 2020, Page(s) 218-220, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2019.12.034

Intellectual Property Rights

Patent (1)

METHODS AND PROBIOTIC COMPOSITIONS FOR THE TREATMENT OF BONE DISORDERS

Application/Publication number: 19 864106
Date: 2019-09-27
Applicant(s): UNIVERSITE DE GENEVE