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Oncolytic viruses for the treatment of pediatric brain tumors: An integrated clinical and lab approach

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Publications

CD137 and PD-L1 targeting with immunovirotherapy induces a potent and durable antitumor immune response in glioblastoma models

Author(s): Montserrat Puigdelloses, Marc Garcia-Moure, Sara Labiano, Virginia Laspidea, Marisol Gonzalez-Huarriz, Marta Zalacain, Lucia Marrodan, Naiara Martinez-Velez, Daniel De la Nava, Iker Ausejo, Sandra Hervás-Stubbs, Guillermo Herrador, ZhiHong Chen, Dolores Hambardzumyan, Ana Patino Garcia, Hong Jiang, Candelaria Gomez-Manzano, Juan Fueyo, Jaime Gállego Pérez-Larraya, Marta Alonso
Published in: Journal for ImmunoTherapy of Cancer, Issue 9/7, 2021, Page(s) e002644, ISSN 2051-1426
DOI: 10.1136/jitc-2021-002644

RNU6-1 in circulating exosomes differentiates GBM from non-neoplastic brain lesions and PCNSL but not from brain metastases

Author(s): Montserrat Puigdelloses, Marisol González-Huárriz, Marc García-Moure, Naiara Martínez-Vélez, Inés Esparragosa Vázquez, Jordi Bruna, Beatriz Zandio, Amaia Agirre, Miguel Marigil, Gregorio Petrirena, Jorge M Nuñez-Córdoba, Sonia Tejada-Solís, Ricardo Díez-Valle, Jaime Gállego-Culleré, Eduardo Martínez-Vila, Ana Patiño-García, Marta M Alonso, Jaime Gállego Pérez-Larraya
Published in: Neuro-Oncology Advances, Issue 2/1, 2020, ISSN 2632-2498
DOI: 10.1093/noajnl/vdaa010

Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models

Author(s): Naiara Martinez-Velez, Miguel Marigil, Marc García-Moure, Marisol Gonzalez-Huarriz, Jose Javier Aristu, Luis-Isaac Ramos-García, Sonia Tejada, Ricardo Díez-Valle, Ana Patiño-García, Oren J. Becher, Candelaria Gomez-Manzano, Juan Fueyo, Marta M. Alonso
Published in: Acta Neuropathologica Communications, Issue 7/1, 2019, ISSN 2051-5960
DOI: 10.1186/s40478-019-0714-6

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

Author(s): Naiara Martínez-Vélez, Marc Garcia-Moure, Miguel Marigil, Marisol González-Huarriz, Montse Puigdelloses, Jaime Gallego Pérez-Larraya, Marta Zalacaín, Lucía Marrodán, Maider Varela-Guruceaga, Virginia Laspidea, Jose Javier Aristu, Luis Isaac Ramos, Sonia Tejada-Solís, Ricardo Díez-Valle, Chris Jones, Alan Mackay, Jose A. Martínez-Climent, Maria Jose García-Barchino, Eric Raabe, Michelle
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-10043-0

The Importance of Gender-Related Anticancer Research on Mitochondrial Regulator Sodium Dichloroacetate in Preclinical Studies In Vivo

Author(s): Donatas Stakišaitis, Milda Juknevičienė, Eligija Damanskienė, Angelija Valančiūtė, Ingrida Balnytė, Marta Maria Alonso
Published in: Cancers, Issue 11/8, 2019, Page(s) 1210, ISSN 2072-6694
DOI: 10.3390/cancers11081210

The oncolytic adenovirus VCN-01 promotes anti-tumor effect in primitive neuroectodermal tumor models

Author(s): Marc Garcia-Moure, Naiara Martinez-Velez, Marisol Gonzalez-Huarriz, Lucía Marrodán, Manel Cascallo, Ramón Alemany, Ana Patiño-García, Marta M. Alonso
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
DOI: 10.1038/s41598-019-51014-1

Local administration of IL-12 with an HC vector results in local and metastatic tumor control in pediatric osteosarcoma

Author(s): Marta Zalacain, María Bunuales, Lucía Marrodan, Sara Labiano, Marisol Gonzalez-Huarriz, Naiara Martinez-Vélez, Virginia Laspidea, Montse Puigdelloses, Marc García-Moure, Manuela Gonzalez-Aparicio, Rubén Hernandez-Alcoceba, Marta M. Alonso, Ana Patiño-García
Published in: Molecular Therapy - Oncolytics, Issue 20, 2021, Page(s) 23-33, ISSN 2372-7705
DOI: 10.1016/j.omto.2020.11.003

Delta-24-RGD, an Oncolytic Adenovirus, Increases Survival and Promotes Proinflammatory Immune Landscape Remodeling in Models of AT/RT and CNS-PNET

Author(s): Marc Garcia-Moure, Marisol Gonzalez-Huarriz, Sara Labiano, Elizabeth Guruceaga, Eva Bandres, Marta Zalacain, Lucia Marrodan, Carlos de Andrea, Maria Villalba, Naiara Martinez-Velez, Virginia Laspidea, Montse Puigdelloses, Jaime Gallego Perez-Larraya, Ignacio Iñigo-Marco, Renata Stripecke, Jennifer A. Chan, Eric H. Raabe, Marcel Kool, Candelaria Gomez-Manzano, Juan Fueyo, Ana Patiño-García, Mart
Published in: Clinical Cancer Research, Issue 27/6, 2021, Page(s) 1807-1820, ISSN 1078-0432
DOI: 10.1158/1078-0432.ccr-20-3313

Destress and do not suppress: targeting adrenergic signaling in tumor immunosuppression

Author(s): Ignacio Iñigo-Marco, Marta M. Alonso
Published in: Journal of Clinical Investigation, Issue 129/12, 2019, Page(s) 5086-5088, ISSN 0021-9738
DOI: 10.1172/jci133115

Hitchhiking to brain tumours: stem cell delivery of oncolytic viruses

Author(s): Juan Fueyo, Candelaria Gomez-Manzano, Frederick F Lang, Marta M Alonso
Published in: The Lancet Oncology, Issue 22/8, 2021, Page(s) 1049-1051, ISSN 1470-2045
DOI: 10.1016/s1470-2045(21)00296-5