PROTEIN TYROSINE PHOSPHATASES IN METABOLIC DISEASES: OXIDATION, DYSFUNCTION AND THERAPEUTIC POTENTIAL

Publications

Peer reviewed articles (5)

PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes

Author(s): Bernat Elvira; Valerie Vandenbempt; Julia Bauzá-Martinez; Raphaël Crutzen; Javier Negueruela; Hazem Ibrahim; Matthew L. Winder; Manoja K. Brahma; Beata Vekeriotaite; Pieter-Jan Martens; Sumeet Pal Singh; Fernando Rossello; Pascale Lybaert; Timo Otonkoski ; Conny Gysemans ; Wei Wu; Esteban N. Gurzov
Published in: Diabetes, Volume 71, Issue 4, 2022, ISSN 0012-1797
Publisher: American Diabetes Association
DOI: 10.2337/db21-0443

STAT3 Regulates Mitochondrial Gene Expression in Pancreatic β-Cells and Its Deficiency Induces Glucose Intolerance in Obesity

Author(s): Anaïs Schaschkow, Lokman Pang, Valerie Vandenbempt, Bernat Elvira, Sara A. Litwak, Beata Vekeriotaite, Elisa Maillard, Marjorie Vermeersch, Flavia M.M. Paula, Michel Pinget, David Perez-Morga, Daniel J. Gough, Esteban N. Gurzov
Published in: Diabetes, 70/9, 2021, Page(s) 2026-2041, ISSN 0012-1797
Publisher: American Diabetes Association
DOI: 10.2337/db20-1222

Insulin-Binding Peptide Probes Provide a Novel Strategy for Pancreatic β-Cell Imaging

Author(s): Maria Eriksson, Sara A. Litwak, Yan Yun, William J. Stanley, Peter Thorn, Ulf Ahlgren, Esteban N. Gurzov
Published in: Molecular Pharmaceutics, 2021, ISSN 1543-8384
Publisher: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.1c00616

Novel Strategies to Protect and Visualize Pancreatic β Cells in Diabetes

Author(s): Esteban N. Gurzov, Pu Chun Ke, Ulf Ahlgren, Rita S. Garcia Ribeiro, Martin Gotthardt
Published in: Trends in Endocrinology & Metabolism, 2020, ISSN 1043-2760
Publisher: Elsevier BV
DOI: 10.1016/j.tem.2020.10.002

Oxidative stress in obesity-associated hepatocellular carcinoma: sources, signaling and therapeutic challenges

Author(s): Manoja K. Brahma, Eduardo H. Gilglioni, Lang Zhou, Eric Trépo, Pengyu Chen, Esteban N. Gurzov
Published in: Oncogene, 40/33, 2021, Page(s) 5155-5167, ISSN 0950-9232
Publisher: Nature Publishing Group
DOI: 10.1038/s41388-021-01950-y