Genome-wide surveys and functional analysis of pancreatic cancer metastasis drivers

Project Information

PACA-MET

Grant agreement ID: 819642

DOI 10.3030/819642

EC signature date 19 February 2019

Start date 1 November 2019

End date 31 October 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 995 875,00

EU contribution € 1 995 875,00

Coordinated by

KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
Germany

Publications

Peer reviewed articles (7)

Tutorial: design and execution of CRISPR in vivo screens.

Author(s): Braun CJ, Adames AC, Saur D, Rad R
Published in: Nature Protocols, 2022, ISSN 1754-2189
Publisher: Nature Publishing Group

CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver

Author(s): Kaltenbacher T, Löprich J, Maresch R, Weber J, Müller S, Oellinger R, Groß N, Griger J, de Andrade Krätzig N, Avramopoulos P, Ramanujam D, Brummer S, Widholz SA, Bärthel S, Falcomatà C, Pfaus A, Alnatsha A, Mayerle J, Schmidt-Supprian M, Reichert M, Schneider G, Ehmer U, Braun CJ, Saur D, Engelhardt S, Rad R
Published in: Nature protocols, 2022, ISSN 1754-2189
Publisher: Nature Publishing Group

Engineering CRISPR mouse models of cancer

Author(s): Julia Weber, Roland Rad
Published in: Current Opinion in Genetics & Development, Issue 54, 2019, Page(s) 88-96, ISSN 0959-437X
Publisher: Elsevier BV
DOI: 10.1016/j.gde.2019.04.001

Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer

Author(s): Falcomatà C, Bärthel S, Ulrich A, Diersch S, Veltkamp C, Rad L, Boniolo F, Solar M, Steiger K, Seidler B, Zukowska M, Madej J, Wang M, Öllinger R, Maresch R, Barenboim M, Eser S, Tschurtschenthaler M, Mehrabi A, Roessler S, Goeppert B, Kind A, Schnieke A, Robles MS, Bradley A, Schmid RM, Schmidt-Supprian M, Reichert M, Weichert W, Sansom OJ, Morton JP, Rad R, Schneider G, Saur D
Published in: Cancer Discovery, 2021, ISSN 2159-8290
Publisher: American Association for Cancer Research

In vivo functional screening for systems-level integrative cancer genomics.

Author(s): Weber J, Braun CJ, Saur D, Rad R
Published in: Nature Reviews Cancer, 2020, ISSN 1474-175X
Publisher: Nature Publishing Group

Linkage of genetic drivers and strain-specific germline variants confound mouse cancer genome analyses.

Author(s): Mueller S, Lange S, Collins KAN, Krebs S, Blum H, Schneider G, Rad L, Saur D, Rad R
Published in: Nature communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group

Analysis pipelines for cancer genome sequencing in mice

Author(s): Sebastian Lange, Thomas Engleitner, Sebastian Mueller, Roman Maresch, Maximilian Zwiebel, Laura González-Silva, Günter Schneider, Ruby Banerjee, Fengtang Yang, George S. Vassiliou, Mathias J. Friedrich, Dieter Saur, Ignacio Varela, Roland Rad
Published in: Nature Protocols, Issue 15/2, 2020, Page(s) 266-315, ISSN 1754-2189
Publisher: Nature Publishing Group
DOI: 10.1038/s41596-019-0234-7