Supramolecular engineering of glycan-decorated peptides as synthetic vaccines

Project Information

SUPRAVACC

Grant agreement ID: 819856

DOI 10.3030/819856

EC signature date 20 March 2019

Start date 1 April 2019

End date 31 March 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 000 000,00

EU contribution € 2 000 000,00

Coordinated by

JOHANNES GUTENBERG-UNIVERSITAT MAINZ
Germany

Publications

Peer reviewed articles (4)

MUC1 Glycopeptide Vaccine Modified with a GalNAc Glycocluster Targets the Macrophage Galactose C-type Lectin on Dendritic Cells to Elicit an Improved Humoral Response

Author(s): Adele Gabba; Riem Attariya; Sandra Behren; Christian Pett; Joost C. van der Horst; Hajime Yurugi; Jin Yu; Moritz Urschbach; Juan Sabin; Gabriel Birrane; Edgar Schmitt; Sandra J. van Vliet; Pol Besenius; Ulrika Westerlind; Paul V. Murphy
Published in: J. Am. Chem. Soc., 2023, Page(s) 13027-13037, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c12843

Modular Platform of Carbohydrates-modified Supramolecular Polymers Based on Dendritic Peptide Scaffolds

Author(s): Long Li; Libin Wu; Moritz Urschbach; David Straßburger; Xiaomei Liu; Pol Besenius; Guosong Chen
Published in: ACS Polym. Au, 2022, Page(s) 478-485, ISSN 2694-2453
Publisher: ACS
DOI: 10.1021/acspolymersau.2c00032

Impact of sample history and solvent effects on pathway control in the supramolecular polymerisation of Au(<scp>i</scp>)-metallopeptide amphiphiles

Author(s): Marius Thomas; Vanessa Lewe; Jonas Kölsch; Moritz Urschbach; Jessica Erlenbusch; Oliver Sven Stach; Pol Besenius
Published in: Polym. Chem., 2023, Page(s) 1888-1892, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3py00053b

The Development of Vaccines from Synthetic Tumor-Associated Mucin Glycopeptides and their Glycosylation-Dependent Immune Response

Author(s): Dr. Natascha Stergiou, Moritz Urschbach, Dr. Adele Gabba, Prof. Edgar Schmitt, Prof. Horst Kunz, Prof. Pol Besenius
Published in: The Chemical Record, 2021, Page(s) 3313-3331, ISSN 1527-8999
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/tcr.202100182