Supramolecular engineering of glycan-decorated peptides as synthetic vaccines

Project Information

SUPRAVACC

Grant agreement ID: 819856

DOI

10.3030/819856

Project closed

EC signature date 20 March 2019

Start date 1 April 2019

End date 30 September 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

JOHANNES GUTENBERG-UNIVERSITAT MAINZ
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

MUC1 Glycopeptide Vaccine Modified with a GalNAc Glycocluster Targets the Macrophage Galactose C-type Lectin on Dendritic Cells to Elicit an Improved Humoral Response

Author(s): Adele Gabba; Riem Attariya; Sandra Behren; Christian Pett; Joost C. van der Horst; Hajime Yurugi; Jin Yu; Moritz Urschbach; Juan Sabin; Gabriel Birrane; Edgar Schmitt; Sandra J. van Vliet; Pol Besenius; Ulrika Westerlind; Paul V. Murphy
Published in: J. Am. Chem. Soc., 2023, Page(s) 13027-13037, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c12843

Aliphatic polycarbonates with acid degradable ketal side groups as multi-pH-responsive immunodrug nanocarriers

Author(s): Adrian V. Hauck, Patric Komforth, Jessica Erlenbusch, Judith Stickdorn, Krzysztof Radacki, Holger Braunschweig, Pol Besenius, Simon Van Herck, Lutz Nuhn
Published in: Biomaterials Science, Issue 13, 2025, Page(s) 1414-1425, ISSN 2047-4830
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4bm00949e

Modular Platform of Carbohydrates-modified Supramolecular Polymers Based on Dendritic Peptide Scaffolds

Author(s): Long Li; Libin Wu; Moritz Urschbach; David Straßburger; Xiaomei Liu; Pol Besenius; Guosong Chen
Published in: ACS Polym. Au, 2022, Page(s) 478-485, ISSN 2694-2453
Publisher: ACS
DOI: 10.1021/acspolymersau.2c00032

Cucurbit[8]uril Mediated Supramolecular and Photocrosslinked Interpenetrating Network Hydrogel Matrices for 3D‐Bioprinting

Author(s): Yuqing Wang, Alexander Matthias Bimmermann, Meik Neufurth, Pol Besenius
Published in: Advanced Materials, Issue 36, 2024, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202313270

Supramolecular Assembly and Thermogelation Strategies Using Peptide–Polymer Conjugates

Author(s): Chloé Pascouau, Maren Schweitzer, Pol Besenius
Published in: Biomacromolecules, Issue 25, 2025, Page(s) 2659-2678, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.4c00031

Impact of sample history and solvent effects on pathway control in the supramolecular polymerisation of Au(<scp>i</scp>)-metallopeptide amphiphiles

Author(s): Marius Thomas; Vanessa Lewe; Jonas Kölsch; Moritz Urschbach; Jessica Erlenbusch; Oliver Sven Stach; Pol Besenius
Published in: Polym. Chem., 2023, Page(s) 1888-1892, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3py00053b

Regulating H₂S release from self-assembled peptide H₂S-donor conjugates using cysteine derivatives

Author(s): Zhao Li, Marius Thomas, Christian M. Berač, Oliver S. Stach, Pol Besenius, John B. Matson
Published in: Organic &amp; Biomolecular Chemistry, Issue 22, 2024, Page(s) 8173-8181, ISSN 1477-0520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4ob01148a

The Development of Vaccines from Synthetic Tumor-Associated Mucin Glycopeptides and their Glycosylation-Dependent Immune Response

Author(s): Natascha Stergiou; Moritz Urschbach; Adele Gabba; Edgar Schmitt; Horst Kunz; Pol Besenius
Published in: The Chemical Record, 2021, Page(s) 3313-3331, ISSN 1527-8999
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/tcr.202100182

The Impact of Single Amino Acid Insertion on the Supramolecular Assembly Pathway of Aromatic Peptide Amphiphiles

Author(s): Ayato Higuchi, Arka Som, Rie Wakabayashi, Masahiro Goto, Noriho Kamiya, Pol Besenius
Published in: Chemistry – A European Journal, Issue 31, 2025, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202404233

Other (1)

Non-equilibrium Spatiotemporal Patterns of Charge-transfer Supramolecular Assembly

Author(s): Surbhi Sharma, Mohit Kumar, Jessica Erlenbusch, Ankit Sakhuja, Subi J. George, Shikha Dhiman
Published in: 2024
Publisher: ChemRxiv
DOI: 10.26434/chemrxiv-2024-r3l1b