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Supramolecular engineering of glycan-decorated peptides as synthetic vaccines

Project description

A novel vaccine 'train' carries a diversely qualified team to the station

Vaccines are currently being made by tacking a natural antigen – a component of the offending microbe recognised by the immune system – onto a carrier protein. While this method has achieved significant gains in the realm of public health, the vaccines are rather limited in scope/function, and the current large protein molecule formulations have limited stability and shelf life. Sort of like a building manager with a lot of keys on their key ring, the EU-funded SUPRAVACC project's synthetic multipotent vaccines will carry multiple different immunostimulants and antigens. Their stability will get a boost from the reliance on small molecules rather than large delicate proteins. In short, the technology could revolutionise vaccine scope and vaccination speed and efficacy.

Host institution

JOHANNES GUTENBERG-UNIVERSITAT MAINZ
Net EU contribution
€ 1 924 752,50
Address
Saarstrasse 21
55122 Mainz
Germany

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Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 924 752,50

Beneficiaries (2)

JOHANNES GUTENBERG-UNIVERSITAT MAINZ
Germany
Net EU contribution
€ 1 924 752,50
Address
Saarstrasse 21
55122 Mainz

See on map

Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 924 752,50
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ
Germany
Net EU contribution
€ 75 247,50
Address
Langenbeckstrasse 1
55131 Mainz

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Region
Rheinland-Pfalz Rheinhessen-Pfalz Mainz, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 75 247,50