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Supramolecular engineering of glycan-decorated peptides as synthetic vaccines

Project description

A novel vaccine 'train' carries a diversely qualified team to the station

Vaccines are currently being made by tacking a natural antigen – a component of the offending microbe recognised by the immune system – onto a carrier protein. While this method has achieved significant gains in the realm of public health, the vaccines are rather limited in scope/function, and the current large protein molecule formulations have limited stability and shelf life. Sort of like a building manager with a lot of keys on their key ring, the EU-funded SUPRAVACC project's synthetic multipotent vaccines will carry multiple different immunostimulants and antigens. Their stability will get a boost from the reliance on small molecules rather than large delicate proteins. In short, the technology could revolutionise vaccine scope and vaccination speed and efficacy.

Call for proposal

ERC-2018-COG
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Host institution

JOHANNES GUTENBERG-UNIVERSITAT MAINZ
Address
Saarstrasse 21
55122 Mainz
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 000 000

Beneficiaries (1)

JOHANNES GUTENBERG-UNIVERSITAT MAINZ
Germany
EU contribution
€ 2 000 000
Address
Saarstrasse 21
55122 Mainz
Activity type
Higher or Secondary Education Establishments