Matching CNS Lineage Maps with Molecular Brain Tumor Portraits for Translational Exploitation

Project description

Molecular characterisation of brain tumours

Brain tumours are heterogeneous and, unlike haematopoietic malignancies, the cell of origin is unknown in most cases. BRAIN-MATCH, an EU-funded initiative, aims to understand brain tumour biology by analysing the molecular profiles of normal brain cells at different stages during development at single cell resolution and integrating with thousands of brain tumour datasets that cover more than 100 different brain tumour entities. This integrative approach will help scientists identify the cells of origin for many of these tumours. Project results also have clinical projections and aim at hinting to novel therapies and liquid biopsy-based assays for the detection of tumour cells circulating in the blood.

Fields of science

• medical and health sciences › clinical medicine › oncology

Programme(s)

• H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme

Topic(s)

• ERC-2018-COG - ERC Consolidator Grant

Call for proposal

ERC-2018-COG

See other projects for this call

Funding Scheme

ERC-COG - Consolidator Grant

Host institution

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

Net EU contribution

€ 1 999 875,00

Address

Im Neuenheimer Feld 280
69120 Heidelberg
Germany

Region

Baden-Württemberg › Karlsruhe › Heidelberg, Stadtkreis

Activity type

Research Organisations

Links

Non-EU contribution

€ 0,00

Beneficiaries (1)

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

Germany

Net EU contribution

€ 1 999 875,00

Address

Im Neuenheimer Feld 280
69120 Heidelberg

Region

Baden-Württemberg › Karlsruhe › Heidelberg, Stadtkreis

Activity type

Research Organisations

Links

Non-EU contribution

€ 0,00