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Matching CNS Lineage Maps with Molecular Brain Tumor Portraits for Translational Exploitation

Project description

Molecular characterisation of brain tumours

Brain tumours are heterogeneous and, unlike haematopoietic malignancies, the cell of origin is unknown in most cases. BRAIN-MATCH, an EU-funded initiative, aims to understand brain tumour biology by analysing the molecular profiles of normal brain cells at different stages during development at single cell resolution and integrating with thousands of brain tumour datasets that cover more than 100 different brain tumour entities. This integrative approach will help scientists identify the cells of origin for many of these tumours. Project results also have clinical projections and aim at hinting to novel therapies and liquid biopsy-based assays for the detection of tumour cells circulating in the blood.

Host institution

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Net EU contribution
€ 1 999 875,00
Address
Im Neuenheimer Feld 280
69120 Heidelberg
Germany

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Research Organisations
Non-EU contribution
€ 0,00

Beneficiaries (1)

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
Net EU contribution
€ 1 999 875,00
Address
Im Neuenheimer Feld 280
69120 Heidelberg

See on map

Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Research Organisations
Non-EU contribution
€ 0,00