Conservation of European Biodiversity through Exploitation of Traditional Herbal Knowledge for the Development of Innovative Products

Project Information

EthnoHERBS

Grant agreement ID: 823973

DOI

10.3030/823973

Project closed

EC signature date 5 July 2019

Start date 1 October 2019

End date 31 March 2025

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 2 447 200,00

EU contribution

€ 2 447 200,00

Coordinated by

ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON
Greece

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (2)

Report on Workshops organisation and outreach activities.

Two workshops and a final event will take place during the project. The workshops and the event will be opened to schools/university students and will be combined if possible with other major events in the field (e.g. international conferences). Moreover, other outreach activities such as (summer classes, TV shows etc.) will be organized.

Mid-term meeting

It is a report on the actions of the Midterm Meeting

Websites, patent fillings, videos etc. (1)

Website construction

A website will be established The website will be open to public for certain information and will also act as a communication tool among partners and as a dissemination tool for all meetings reports

Publications

Peer reviewed articles (22)

Rosehip Extract-Loaded Liposomes for Potential Skin Application: Physicochemical Properties of Non- and UV-Irradiated Liposomes

Author(s): Aleksandra A. Jovanovic, Bojana Balanc , Mina Volic, Ilinka Pecinar , Jelena Živkovic and Katarina P. Šavikin
Published in: Plants, 2023, ISSN 2223-7747
Publisher: MDPI
DOI: 10.3390/plants12173063

Secondary Metabolites in Edible Species: Looking beyond Nutritional Value

Author(s): Ana M. L. Seca and Antoaneta Trendafilova
Published in: Foods, 2021, ISSN 2304-8158
Publisher: MDPI
DOI: 10.3390/foods10051131

Examining Hemin and its Derivatives: Induction of Heme-Oxygenase-1 Activity and Oxidative Stress in Breast Cancer Cells through Collaborative Experimental Analysis and Molecular Dynamics Simulations

Author(s): Amir M. Alsharabasy, Panagiotis I. Lagarias, Konstantinos D. Papavasileiou, Antreas Afantitis, Pau Farràs, Sharon Glynn, Abhay Pandit
Published in: Journal of Medicinal Chemistry, Issue 67, 2024, Page(s) 15411-15427, ISSN 0022-2623
Publisher: American Chemical Society
DOI: 10.1021/acs.jmedchem.4c00989

Plant Resin Delivery by Nanovectors as an Emerging Approach to Boost Solubility, Permeability and Bioavailability

Author(s): Eleonora Truzzi, Giulia Vanti, Lucia Grifoni, Eleonora Maretti, Eliana Leo, Anna Rita Bilia
Published in: Pharmaceutics, Issue 17, 2025, Page(s) 53, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics17010053

A Systematic Review of Deep Learning Methodologies Used in the Drug Discovery Process with Emphasis on In Vivo Validation

Author(s): Nikoletta-Maria Koutroumpa, Konstantinos D. Papavasileiou, Anastasios G. Papadiamantis, Georgia Melagraki, Antreas Afantitis
Published in: International Journal of Molecular Sciences, Issue 24, 2023, Page(s) 6573, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24076573

Systematic Review of Naturally Derived Substances That Act as Inhibitors of the Nicotine Metabolizing Enzyme Cytochrome P450 2A6

Author(s): Haralampos Tzoupis, Konstantinos D. Papavasileiou, Stavros Papatzelos, Angelos Mavrogiorgis, Lefteris C. Zacharia, Georgia Melagraki, Antreas Afantitis
Published in: International Journal of Molecular Sciences, Issue 25, 2024, Page(s) 8031, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25158031

In Silico Identification and Evaluation of Natural Products as Potential Tumor Necrosis Factor Function Inhibitors Using Advanced Enalos Asclepios KNIME Nodes

Author(s): Dimitra Papadopoulou, Antonios Drakopoulos, Panagiotis Lagarias, Georgia Melagraki, George Kollias, Antreas Afantitis
Published in: International Journal of Molecular Sciences, Issue 22, 2025, Page(s) 10220, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms221910220

Traditional knowledge on use of medicinal plants in CentralBalkans for treating eczema

Author(s): Sostaric, Ivan, Kilibarda, Sofija, Kolašinac, Stefan, Aćić, Svetlana, Dajić Stevanović, Zora
Published in: Macedonian pharmaceutical bulletin, 2022, ISSN 1857-8969
Publisher: Macedonian Pharmaceutical Association
DOI: 10.33320/maced.pharm.bull.2022.68.04.083

Prediction of blood–brain barrier and Caco-2 permeability through the Enalos Cloud Platform: combining contrastive learning and atom-attention message passing neural networks

Author(s): Nikoletta-Maria Koutroumpa, Andreas Tsoumanis, Haralambos Sarimveis, Iseult Lynch, Georgia Melagraki, Antreas Afantitis
Published in: Journal of Cheminformatics, Issue 17, 2025, ISSN 1758-2946
Publisher: Chemistry Central
DOI: 10.1186/s13321-025-01007-2

Some European Gentiana Species Are Used Traditionally to Cure Wounds: Bioactivity and Conservation Issues

Author(s): Ardalan Pasdaran, Zheko Naychov, Daniela Batovska, Philip Kerr , Adrien Favre, Vladimir Dimitrov , Ina Aneva , Azadeh Hamedi and Ekaterina Kozuharova
Published in: Diversity, 2023, ISSN 1424-2818
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/d15030467

Ethnopharmacological study of medicinal plants used against skin ailments on Mount Pelion, central Greece

Author(s): Tsioutsiou Evelina, Cheilari Antigoni, ALIGIANNIS NEKTARIOS
Published in: Frontiers, Issue 2, 2023, ISSN 1663-9812
Publisher: Frontiers Media S.A.
DOI: 10.3389/fphar.2023.1225580

Ultrasound-Assisted Water Extraction of Gentiopicroside, Isogentisin, and Polyphenols from Willow Gentian “Dust” Supported by Hydroxypropyl-β-Cyclodextrin as Cage Molecules

Author(s): Jovanović, M.S.; Krgović, N.; Šavikin, K.; Živković, J.
Published in: Molecules, 2022, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules27217606

Gentians, natural remedies for future of visceral pain control; an ethnopharmacological review with an in silico approach

Author(s): Ardalan Pasdaran, Daniela Butovska, Philip Kerr, Zheko Naychov, Ina Aneva, Ekaterina Kozuharova
Published in: Biologia Futura, Issue 73, 2022, Page(s) 219-227, ISSN 2676-8615
Publisher: Springer Nature
DOI: 10.1007/s42977-022-00114-7

Discovery of bioactive natural products with skin beneficialproperties through the exploitation of ethnobotanical studiesconducted in the Balkans

Author(s): Efthymia Eleni Tsioutsiou, Antigoni Cheilari, Nektarios Aligiannis
Published in: Macedonian pharmaceutical bulletin, 2022, ISSN 1857-8969
Publisher: Skopje: Makedonsko farmacevtsko društvo
DOI: 10.33320/maced.pharm.bull.2022.68.04.072

Research Advances on Health Effects of Edible Artemisia Species and Some Sesquiterpene Lactones Constituents

Author(s): Trendafilova, A.; Moujir, L.M.; Sousa, P.M.C.; Seca, A.M.L.
Published in: Foods, Issue 23048158, 2021, ISSN 2304-8158
Publisher: MDPI
DOI: 10.3390/foods10010065

Medicinal Plants Used Traditionally for Skin Related Problems in the South Balkan and East Mediterranean Region—A Review

Author(s): Efthymia Eleni Tsioutsiou, Vaios Amountzias, Argyro Vontzalidou, Evanthia Dina, Zora Dajić Stevanović, Antigoni Cheilari, Nektarios Aligiannis
Published in: Frontiers in Pharmacology, 2022, ISSN 1663-9812
Publisher: Frontiers Media S.A.
DOI: 10.3389/fphar.2022.936047

HPTLC Combined with sHetCA and Multivariate Statistics for the Detection of Bioactive Compounds in Complex Mixtures

Author(s): Vaios Amountzias, Evagelos Gikas, Nektarios Aligiannis
Published in: Molecules, Issue 29, 2024, Page(s) 6027, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules29246027

Bioassay-Guided Skin-Beneficial Effects of Fractionated Sideritis raeseri subsp. raeseri Extract.

Author(s): Krgović, N.; Jovanović, M.; Aradski, A.A.; Janković, T.; Stević, T.; Zdunić, G.; Laušević, S.D.; Šavikin, K.
Published in: Plants, Issue 22237747, 2022, ISSN 2223-7747
Publisher: MDPI
DOI: 10.3390/plants11202677

Ultrasound-Assisted Natural Deep Eutectic Solvents Extraction of Bilberry Anthocyanins: Optimization, Bioactivities, and Storage Stability

Author(s): Jovanović, M.S.; Krgović, N.; Živković, J.; Stević, T.; Zdunić, G.; Bigović, D.; Šavikin, K.
Published in: Plants, Issue 22237747, 2022, ISSN 2223-7747
Publisher: MDPI
DOI: 10.3390/plants11202680

EthnoHERBS: Harnessing traditional herbal knowledge for biodiversity conservation and innovative health solutions

Author(s): Dimitrios Zouraris, Konstantia Graikou, Panagiotis Vasileiou, Vladimir Dimitrov, Zora Dajic Stevanovic, Anna Rita Bilia, Jelena Zivkovic, Alberto Dias, Konstantinos Kasiotis, Konstantinos Gardikis, Paula Dias, Mirko Oluški, Juan Ramón Muñoz Montaño, Hristina Hristova, Hristo Iliev, Giovanna Petrangolini, Antreas Afantitis, Nektarios Aligiannis
Published in: Computational and Structural Biotechnology Journal, Issue 29, 2025, Page(s) 85-94, ISSN 2001-0370
Publisher: Elsevier BV
DOI: 10.1016/j.csbj.2025.03.035

Can NMR-HetCA be a Reliable Prediction Tool for the Direct Identification of Bioactive Substances in Complex Mixtures?

Author(s): Vaios Amountzias, Antigoni Cheilari, Argyro Vontzalidou, Dimitra Benaki, Evagelos Gikas, Nektarios Aligiannis
Published in: Analytical Chemistry, Issue 96, 2024, Page(s) 20090-20097, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.4c05080

Liposomal Bilayer as a Carrier of Rosa canina L. Seed Oil: Physicochemical Characterization, Stability, and Biological Potential

Author(s): Aleksandra A. Jovanovic, Danica Cujic, Bojan Stojadinovic , Natalija ˇCutovic , Jelena Živkovic and Katarina Šavikin
Published in: Molecules, 2023, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules28010276

Conference proceedings (3)

Bioactivity of carotenoids and their role in skin disorders: from tradition to application

Author(s): Zora Dajić Stevanović, Nektarios Aligiannis, Konstantia Graikou, Anna Rita Bilia, Stefan Kolašinac, Sofija Kilibarda
Published in: Macedonian pharmaceutical bulletin, 2022
Publisher: Macedonian pharmaceutical bulletin
DOI: 10.33320/maced.pharm.bull.2022.68.04.067

EthnoHERBS: Conservation of European Biodiversity through Exploitation of Traditional Herbal Knowledge for the Development of Innovative Products

Author(s): Nektarios Aligiannis
Published in: Macedonian pharmaceutical bulletin, 2022, ISSN 1857-8969
Publisher: Macedonian pharmaceutical bulletin
DOI: 10.33320/maced.pharm.bull.2022.68.04.004

Conservation of European Biodiversity through Exploitation of Traditional Herbal Knowledge for the Development of Innovative Products

Author(s): Konstantia Graikou, Nikolaos Fokialakis, Vladimir Dimitrov, Zora Dajic, Anna Rita Bilia, Jelena Zivkovic, Alberto Dias, Konstantinos Kasiotis, Antreas Afantitis, Konstantinos Gardikis, Mirko Oluški, Juan Ramón Muñoz Montaño, Nektarios Aligiannis
Published in: Macedonian pharmaceutical bulletin, 2022
Publisher: Macedonian pharmaceutical bulletin
DOI: 10.33320/maced.pharm.bull.2022.68.04.041