A neuroprosthesis to restore the vagal-cardiac closed-loop connection after heart transplantation

Livrables

Workshop on ethics, law and policies for smart cardiac prostheses

Organization of a workshop on ethics law and policies for smart cardiac prostheses

Results of the extensive study of the anatomy and functional units of the VN cardiac afferents

Final report on regulatory, ethical and legal issues

Analysis of all regulatory ethical and legal issues related to the development and use of the NeuHeart cardiac neuroprosthesis

Integrated protocol for biomarker autonomic function monitoring

Monitoring of circulating biomarkers related to cardiovascular VN activity

Publications

Mapping the functional anatomy and topography of the cardiac autonomic innervation for selective cardiac neuromodulation using MicroCT

Auteurs: Bettina Kronsteiner, Lydia M Zopf, Patrick Heimel, Gunpreet Oberoi, Anne M Kramer, Paul Slezak, Wolfgang J Weninger, Bruno K Podesser, Attila Kiss, Francesco Moscato
Publié dans: Frontiers in Cell and Developmental Biology, 2022, ISSN 2296-634X
Éditeur: usanne: Frontiers Media S.A., 2013-
DOI: 10.3389/fcell.2022.968870

Accurate, Very Low Computational Complexity Spike Sorting Using Unsupervised Matched Subspace Learning

Auteurs: Zamani M, Sokolic J, Jiang D, Renna F, Rodrigues MRD, Demosthenous A
Publié dans: IEEE Trans Biomed Circuits Syst, Numéro Apr;14(2):221-231, 2020, ISSN 1940-9990
Éditeur: IEEE
DOI: 10.1109/tbcas.2020.2969910

Time Stamp – A Novel Time-to-Digital Demodulation Method for Bioimpedance Implant Applications

Auteurs: Wu Y, Jiang D, Habibollahi M, Almarri N, Demosthenous A
Publié dans: IEEE Trans Biomed Circuits Syst, Numéro Oct;14(5):997-1007, 2020, ISSN 1940-9990
Éditeur: IEEE
DOI: 10.1109/tbcas.2020.3012057

Recent Advances in Polymeric Drug Delivery Systems for Peripheral Nerve Regeneration

Auteurs: Bianchini M, Micera S, Redolfi Riva E.
Publié dans: Pharmaceutics, Numéro 14;15(2):640, 2023, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15020640

Cardiovascular Response to Intraneural Right Vagus Nerve Stimulation in Adult Minipig

Auteurs: Agnesi F, Zinno C, Strauss I, Dushpanova A, Casieri V, Bernini F, Terlizzi D, Gabisonia K, Lionetti V, Micera S.
Publié dans: Neuromodulation: Technology at the Neural Interface, Numéro 29:S1094-7159(23)00131-9, 2023, ISSN 1094-7159
Éditeur: Blackwell Publishing Inc.
DOI: 10.1016/j.neurom.2023.03.002

Progress and challenges of implantable neural interfaces based on nature-derived materials

Auteurs: Eugenio Redolfi Riva, Silvestro Micera
Publié dans: Bioelectronic Medicine, Numéro 7/1, 2021, ISSN 2332-8886
Éditeur: BioMed Central Ltd
DOI: 10.1186/s42234-021-00067-7

Closed-Loop Vagus Nerve Stimulation for the Treatment of Cardiovascular Diseases: State of the Art and Future Directions

Auteurs: Ottaviani MM, Vallone F, Micera S, Recchia FA
Publié dans: Frontiers in Cardiovascular Medicine-Hypertension, 2022, ISSN 2297-055X
Éditeur: Frontiers Media SA
DOI: 10.3389/fcvm.2022.866957

A Fully Implantable Opto-Electro Closed-Loop Neural Interface for Motor Neuron Disease Studies

Auteurs: Liu F, Wu Y, Almarri N, Habibollahi M, Lancashire HT, Bryson B, Greensmith L, Jiang D, Demosthenous A.
Publié dans: IEEE Trans Biomed Circuits Syst, Numéro Oct;16(5):752-765, 2022, ISSN 1940-9990
Éditeur: IEEE
DOI: 10.1109/tbcas.2022.3202026

Changes in Resting and Exercise Hemodynamics Early After Heart Transplantation: A Simulation Perspective

Auteurs: Max Haberbusch, Daniela De Luca, Francesco Moscato
Publié dans: Frontiers in Physiology, Numéro 11, 2020, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2020.579449

A Goertzel Filter-Based System for Fast Simultaneous Multi-Frequency EIS

Auteurs: Regnacq L, Wu Y, Neshatvar N, Jiang D and Demosthenous A
Publié dans: IEEE Transactions on Circuits and Systems II: Express Briefs, Numéro 68(9): 3133-3137, 2021, ISSN 1558-3791
Éditeur: IEEE
DOI: 10.1109/tcsii.2021.3092069

Understanding the heart-brain axis response in COVID-19 patients: A suggestive perspective for therapeutic development

Auteurs: Lionetti V, Bollini S, Coppini R, Gerbino A, Ghigo A, Iaccarino G, Madonna R, Mangiacapra F, Miragoli M, Moccia F, Munaron L, Pagliaro P, Parenti A, Pasqua T, Penna C, Quaini F, Rocca C, Samaja M, Sartiani L, Soda T, Tocchetti CG, Angelone T
Publié dans: Pharmacol Res, Numéro 168:105581, 2021, Page(s) 1-12, ISSN 1096-1186
Éditeur: Elsevier
DOI: 10.1016/j.phrs.2021.105581

Polysaccharide Layer-by-Layer Coating for Polyimide-Based Neural Interfaces

Auteurs: Redolfi Riva E, D'Alessio A, Micera S
Publié dans: Micromachines (Basel), 2022, ISSN 2072-666X
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/mi13050692

Quantification of paravalvular leaks associated with TAVI implants using 4D MRI in an aortic root phantom made possible by the use of 3D printing

Auteurs: Philipp Aigner, Eleonora Sella Bart, Sebastiano Panfili, Tito Körner, Markus Mach, Martin Andreas, Markus Königshofer, Simone Saitta, Alberto Redaelli, Albrecht Schmid, Francesco Moscato
Publié dans: Frontiers in Cardiovascular Medicine, 2023, ISSN 2297-055X
Éditeur: Lausanne: Frontiers Media S.A., 2014-
DOI: 10.3389/fcvm.2023.1083300

Closed-loop vagus nerve stimulation for heart rate control evaluated in the Langendorff-perfused rabbit heart

Auteurs: Max Haberbusch; Bettina Kronsteiner; Anne-Margarethe Kramer; Attila Kiss; Bruno K. Podesser; Francesco Moscato
Publié dans: Crossref, Numéro 5, 2022, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-022-23407-2

A Numerical Model of the Acute Cardiac Effects Provoked by Cervical Vagus Nerve Stimulation

Auteurs: Max Haberbusch, Silvia Frullini, Francesco Moscato
Publié dans: IEEE Transactions on Biomedical Engineering, 2022, ISSN 0018-9294
Éditeur: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2021.3102416

Late plasma exosome microRNA-21-5p depicts magnitude of reverse ventricular remodeling after early surgical repair of primary mitral valve regurgitation

Auteurs: Pizzino F, Furini G, Casieri V, Mariani M, Bianchi G, Storti S, Chiappino D, Maffei S, Solinas M, Aquaro GD, Lionetti V.
Publié dans: Front Cardiovasc Med, Numéro 29;9:943068, 2022, Page(s) 1-21, ISSN 2297-055X
Éditeur: Frontiers
DOI: 10.3389/fcvm.2022.943068

Simultaneous decoding of cardiovascular and respiratory functional changes from pig intraneural vagus nerve signals

Auteurs: Fabio Vallone, Matteo Maria Ottaviani, Francesca Dedola, Annarita Cutrone, Simone Romeni, Adele Macrí Panarese, Fabio Bernini, Marina Cracchiolo, Ivo Strauss, Khatia Gabisonia, Nikoloz Gorgodze, Alberto Mazzoni, Fabio A Recchia, Silvestro Micera
Publié dans: Journal of Neural Engineering, Numéro 18/4, 2021, Page(s) 0460a2, ISSN 1741-2560
Éditeur: Institute of Physics Publishing
DOI: 10.1088/1741-2552/ac0d42

A Multi-Channel Stimulator With High-Resolution Time-to-Current Conversion for Vagal-Cardiac Neuromodulation

Auteurs: Wu Y, Jiang D, Demosthenous A
Publié dans: IEEE Trans Biomed Circuits Syst, Numéro Dec;15(6):1186-1195, 2021, ISSN 1940-9990
Éditeur: IEEE
DOI: 10.1109/tbcas.2021.3139996

Fiber Bragg Gratings for Medical Applications and Future Challenges: A Review

Auteurs: Daniela Lo Presti, Carlo Massaroni, Catia Sofia Jorge Leitao, Maria De Fatima Domingues, Marzhan Sypabekova, David Barrera, Ignazio Floris, Luca Massari, Calogero Maria Oddo, Salvador Sales, Iulian Ioan Iordachita, Daniele Tosi, Emiliano Schena
Publié dans: IEEE Access, Numéro 8, 2020, Page(s) 156863-156888, ISSN 2169-3536
Éditeur: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/access.2020.3019138

Implantable Neural Interfaces and Wearable Tactile Systems for Bidirectional Neuroprosthetics Systems

Auteurs: Annarita Cutrone, Silvestro Micera
Publié dans: Advanced Healthcare Materials, Numéro 8/24, 2019, Page(s) 1801345, ISSN 2192-2640
Éditeur: John Wiley and Sons Ltd
DOI: 10.1002/adhm.201801345

A novel ex-vivo isolated rabbit heart preparation to explore the cardiac effects of cervical and cardiac vagus nerve stimulation

Auteurs: Bettina Kronsteiner, Max Haberbusch, Philipp Aigner, Anne-Margarethe Kramer, Patrick M. Pilz, Bruno K. Podesser, Attila Kiss, Francesco Moscato
Publié dans: Scientific Reports, 2023, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-023-31135-4

A lightweight learning-based decoding algorithm for intraneural vagus nerve activity classification in pigs

Auteurs: Pollina L, Vallone F, Ottaviani MM, Strauss I, Carlucci L, Recchia FA, Micera S, Moccia S
Publié dans: Journal of Neural Engineering, 2022, Page(s) 19 046033, ISSN 1741-2560
Éditeur: Institute of Physics Publishing
DOI: 10.1088/1741-2552/ac84ab

Implantable Fiber Bragg Grating Sensor for Continuous Heart Activity Monitoring: Ex-Vivo and In-Vivo Validation

Auteurs: Ferraro D, D’Alesio G, Camboni D, Zinno C, Costi L, Haberbusch M, Aigner P, Maw M, Schlöglhofer, Unger E, Aliperta A, Bernini F, Casieri V, Terlizzi D, Giudetti G, Carpaneto J, Pedrizzetti G, Micera S, Lionetti V, Moscato F, Massari L, Oddo CM
Publié dans: IEEE Sensors Journal, Numéro 21(13), 2021, Page(s) 14051-14059, ISSN 1558-1748
Éditeur: Institute of Electrical and Electronic Engineers
DOI: 10.1109/jsen.2021.3056530

Bioelectronic medicine for the autonomic nervous system: clinical applications and perspectives

Auteurs: Marina Cracchiolo, Matteo Maria Ottaviani, Alessandro Panarese, Ivo Strauss, Fabio Vallone, Alberto Mazzoni, Silvestro Micera
Publié dans: Journal of Neural Engineering, Numéro 18/4, 2021, Page(s) 041002, ISSN 1741-2560
Éditeur: Institute of Physics Publishing
DOI: 10.1088/1741-2552/abe6b9

A method to establish functional vagus nerve topography from electro-neurographic spontaneous activity

Auteurs: Pitzus A, Romeni S, Vallone F, Micera S
Publié dans: Patterns, Numéro 3(11):100615, 2022, ISSN 2666-3899
Éditeur: Cell Press Elsevier Inc.
DOI: 10.1016/j.patter.2022.100615

Short-Range Quality-Factor Modulation (SQuirM) for Low Power High Speed Inductive Data Transfer

Auteurs: Schormans M, Jiang D, Valente V and Demosthenous A
Publié dans: IEEE Transactions on Circuits and Systems I: Regular Papers, Numéro 66(9):3254-3265, 2019, ISSN 2158-1525
Éditeur: IEEE
DOI: 10.1109/tcsi.2019.2922124

An Implantable Phase Locked Loop MEMS-Based Readout System for Heart Transplantation

Auteurs: Neshatvar N, Schormans M, Jiang D, Schmitt S, Detemple P and Demosthenous A
Publié dans: IEEE Transactions on Circuits and Systems II: Express Briefs, Numéro 69(10):4168-4172, 2022, ISSN 1558-3791
Éditeur: IEEE
DOI: 10.1109/tcsii.2022.3190796

Droits de propriété intellectuelle

INTRAFASCICULAR ELECTRODE IMPLANT

Numéro de demande/publication: 17 791738
Date: 2017-09-29
Demandeur(s): SENSARS NEUROPROSTHETICS SARL

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