Description du projet
Faire progresser l’infrastructure génomique en Europe
Le séquençage de nouvelle génération (NGS pour «next generation sequencing») est une technique de séquençage de pointe qui crée une bibliothèque de fragments et de séquences d’ADN/ARN et qui les classe en parallèle. Il se caractérise par sa vitesse et sa précision élevées, ainsi que par son efficacité haut débit, révolutionnant véritablement la recherche biomédicale de ces dernières années. L’objectif du projet EASI-Genomics, financé par l’UE, est de réduire le coût des services de NGS. À cette fin, le projet offrira un financement à plus de 150 projets afin d’entreprendre des expériences basées sur le NGS. Un cadre qui comprend des services de conception expérimentale, le séquençage et l’analyse des données aidera les chercheurs dans leurs projets et fournira un accès facile à la recherche de haut niveau.
Objectif
Next-generation sequencing (NGS) has taken modern research by storm and consequently is one of the most important tools of modern biological and biomedical research. However, the high cost of instrumentation and reagents, the multifaceted expertise required for correct use and the legal and ethical issues hamper access to NGS technologies for many researchers. EASI-Genomics addresses those challenges by unifying the major European genome centers that provide external access to their facilities. The mission of EASI-Genomics is to facilitate access to cutting-edge DNA sequencing technologies to researchers from both academia and industry, within a framework that ensures compliance with ethical and legal requirements, as well as FAIR and secure data management. EASI-Genomics will provide fully funded access to more than 150 transnational access projects, selected through public calls and a rigorous, fair and transparent peer-review process. Each funded study will be supported from design, through sequencing, to data analysis. EASI-Genomics will provide more than 100 Tb of sequence and more than 25,000 hours of bioinformatic, analytical and data management support to the user community. As outlined in the call, EASI-Genomics will provide access to advanced methods that go beyond what is commercially available. The focus will be on more complex procedures involving short-reads, long-reads, in situ sequencing and single-cell analysis. Complex integrative projects and projects on non-human samples will also be highlighted. Finally, EASI-Genomics will support the wider NGS community to improve their quality control processes by offering open inter-laboratory comparisons allowing them to obtain ISO certification and accreditation in line with many of the EASI-Genomic partners. The EASI-Genomics project aims to build a community of practice, which leverages advanced sequencing technologies beyond country and sector borders to tackle global challenges in science.
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RIA - Research and Innovation actionCoordinateur
08003 Barcelona
Espagne