Descrizione del progetto
Un’infrastruttura genomica avanzata in Europa
Il sequenziamento di prossima generazione è una tecnica di sequenziamento all’avanguardia che crea una biblioteca di frammenti di DNA e RNA e li sequenzia in modo parallelo. Questo metodo è caratterizzato da un’elevata velocità e precisione, nonché efficacia ad alta produttività, e ha davvero rivoluzionato la ricerca biomedica negli ultimi anni. Lo scopo del progetto EASI-Genomics, finanziato dall’UE, è quello di abbassare i costi associati ai servizi di sequenziamento di prossima generazione. A tal fine, EASI-Genomics offrirà finanziamenti destinati a oltre 150 progetti per intraprendere esperimenti basati su questa tecnica. Un quadro comprendente servizi di progettazione sperimentale, sequenziamento e analisi dei dati aiuterà i ricercatori a svolgere i propri progetti e fornirà un facile accesso a ricerca di alto livello.
Obiettivo
Next-generation sequencing (NGS) has taken modern research by storm and consequently is one of the most important tools of modern biological and biomedical research. However, the high cost of instrumentation and reagents, the multifaceted expertise required for correct use and the legal and ethical issues hamper access to NGS technologies for many researchers. EASI-Genomics addresses those challenges by unifying the major European genome centers that provide external access to their facilities. The mission of EASI-Genomics is to facilitate access to cutting-edge DNA sequencing technologies to researchers from both academia and industry, within a framework that ensures compliance with ethical and legal requirements, as well as FAIR and secure data management. EASI-Genomics will provide fully funded access to more than 150 transnational access projects, selected through public calls and a rigorous, fair and transparent peer-review process. Each funded study will be supported from design, through sequencing, to data analysis. EASI-Genomics will provide more than 100 Tb of sequence and more than 25,000 hours of bioinformatic, analytical and data management support to the user community. As outlined in the call, EASI-Genomics will provide access to advanced methods that go beyond what is commercially available. The focus will be on more complex procedures involving short-reads, long-reads, in situ sequencing and single-cell analysis. Complex integrative projects and projects on non-human samples will also be highlighted. Finally, EASI-Genomics will support the wider NGS community to improve their quality control processes by offering open inter-laboratory comparisons allowing them to obtain ISO certification and accreditation in line with many of the EASI-Genomic partners. The EASI-Genomics project aims to build a community of practice, which leverages advanced sequencing technologies beyond country and sector borders to tackle global challenges in science.
Campo scientifico
Parole chiave
Programma(i)
Invito a presentare proposte
Vedi altri progetti per questo bandoBando secondario
H2020-INFRAIA-2018-1
Meccanismo di finanziamento
RIA - Research and Innovation actionCoordinatore
08003 Barcelona
Spagna