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Screening of Gastric Cancer via Breath volatile organic compounds by Hybrid Sensing Approach

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

VOC pattern of gastric juice will provide the headspace analysis results from gastric contents from patients with and without gastric cancer (opens in new window)
First study tissue samples package including relevant approvals (opens in new window)
Delivery of results obtained with three VOGAS analyzer prototypes during continuous field studies at clinical partner locations (opens in new window)
Delivery of set of templates for reporting (opens in new window)
Midterm recruitment report gastric cancer tissues by study site (opens in new window)
Delivery of quality assurance plan will provide a report (opens in new window)
VOC pattern of gastric tissues will provide the headspace analysis results from gastric cancer surgery tissue when compared to non-cancerous tissue (opens in new window)

VOC pattern of gastric tissues will provide the headspace analysis results from gastric cancer surgerytissue when compared to noncancerous tissue

Delivery of the tools for implementation of collaborations will provide a report (opens in new window)
VOC patterns of gastric cancer cell lines will provide the headspace analysis results from gastric cancer cell-lines (opens in new window)

VOC patterns of gastric cancer cell lines will provide the headspace analysis results from gastric cancercelllines

VOC pattern of H. Pylori cultures will provide the headspace analysis results from H. Pylori culture (opens in new window)

VOC pattern of H Pylori cultures will provide the headspace analysis results from H Pylori culture

Breath fingerprint results of gastric cancer based on the GC-MS analysis will be available to differentiate the fingerprint between the cancer and benign conditions (opens in new window)

Breath fingerprint results of gastric cancer based on the GCMS analysis will be available to differentiate the fingerprint between the cancer and benign conditions

Report on status of posting results of the analytical analysis in study registries (opens in new window)
Report on the pepsinogen testing results in plasma conducted to the groups of patients within WP5 and indicating the proportion of subjects with decreased pepsinogen levels (opens in new window)

Publications

In vitro profiling of volatile organic compounds released and consumed by CLS--145 and HGC--27 gastric cell lines (opens in new window)

Author(s): P. Mochalski, A. Leiherer, C. Heinzle, A. Muendlein, D. Ślefarska, L. Mezmale, I. Kikuste, I. Tolmanis, G. Shani, M. Leja, H. Haick
Published in: Helicobacter, Issue e12750, 2020, Page(s) 55, ISSN 1523-5378
Publisher: Wiley
DOI: 10.1111/hel.12745

Analysis of volatile organic compounds emitted by gastric juice (opens in new window)

Author(s): P. Mochalski, L. Mezmale, I. Polaka, I. Kikuste, A.Vanags, I. Tolmanis, V. Veliks, M. Leja
Published in: United European Gastroenterology Journal, Issue 8, 2020, Page(s) 225, ISSN 2050-6414
Publisher: United European Gastroenterology Journal
DOI: 10.1177/2050640620927345

VOC emission sampling from Helicobacter pylori cultures (opens in new window)

Author(s): R. Vangravs; D. Rudzīte; V. Veļiks; M. Leja; P. Mochalski
Published in: Helicobacter, Issue e12647, 2019, Page(s) 127, ISSN 1523-5378
Publisher: Wiley
DOI: 10.1111/hel.12647

Ex-vivo profiling of volatile organic compounds released from gastric cancer and non-cancerous tissue (opens in new window)

Author(s): Daria Slefarska, Linda Mezmale, Ilze Kikuste, Marcis Leja, Pawel Mochalski
Published in: Microbiota in Health and disease, Issue e612, 2021, Page(s) 54, ISSN 2704-8845
Publisher: EHMSG – 34th International Workshop on Helicobacter & Microbiota in Inflammation & Cancer
DOI: 10.26355/mhd_20219_612

Identification of volatile organic compounds emitted by gastric juice (opens in new window)

Author(s): P. Mochalski, L. Mezmale, I. Polaka, I. Kikuste, A.Vanags, I. Tolmanis, V. Veliks, M. Leja
Published in: Helicobacter, Issue e12750, 2020, Page(s) 49, ISSN 1523-5378
Publisher: Wiley
DOI: 10.1111/hel.12745

Combined Chemoresistive and In Situ FTIR Spectroscopy Study of Nanoporous NiO films for Light-Activated Nitrogen Dioxide and Acetone Gas sensing (opens in new window)

Author(s): Katarzyna Drozdowska, Tesfalem Welearegay, Lars Österlund, Janusz Smulko
Published in: Sensors and Actuators B: Chemical, Issue 353, 2022, Page(s) 131125, ISSN 0925-4005
Publisher: Elsevier BV
DOI: 10.1016/j.snb.2021.131125

An Innovative Modular eNose System Based on a Unique Combination of Analog and Digital Metal Oxide Sensors. (opens in new window)

Author(s): Jaeschke, Carsten; Glöckler, Johannes; El Azizi, Oussama; Gonzalez, Oriol; Padilla, Marta; Mitrovics, Jan; Mizaikoff, Boris
Published in: ACS Sensors, Issue 4, 2019, Page(s) 2277–2281, ISSN 2379-3694
Publisher: American Chemical Society (ACS)
DOI: 10.1021/acssensors.9b01244

Characterization of metal oxide gas sensors via optical techniques (opens in new window)

Author(s): Johannes Glöckler, Carsten Jaeschke, Erhan Tütüncü, Vjekoslav Kokoric, Yusuf Kocaöz, Boris Mizaikoff
Published in: Analytical and Bioanalytical Chemistry, Issue 412, 2020, Page(s) 4575-4584, ISSN 1618-2650
Publisher: Springer Link
DOI: 10.1007/s00216-020-02705-6

From Light Pipes to Substrate-Integrated Hollow Waveguides for Gas Sensing: A Review (opens in new window)

Author(s): Diandra Nunes Barreto, Vjekoslav Kokoric, JoãoFlávio da Silveira Petruci, and Boris Mizaikof
Published in: ACS Measurement Science Au, Issue 1, 2021, Page(s) 97-109, ISSN 2694-250X
Publisher: American Chemical Society
DOI: 10.1021/acsmeasuresciau.1c00029

Sensing gastric cancer via point‐of‐care sensor breath analyzer (opens in new window)

Author(s): Leja, Marcis; Kortelainen, Juha M.; Polaka, Inese; Antikainen, Emmi; Mitrovics, J.; Padilla, M.; Mochalski, P.; Shuster, G.; Pohle, Roland; Kashanin, Dmitry; Klemm, Richard; Ikonen, Veikko; Mezmale, Linda; Broza, Yoav Y.; Shani, G.; Haick, Hossam
Published in: Leja , M , Kortelainen , J M , Polaka , I , Turppa , E , Mitrovics , J , Padilla , M , Mochalski , P , Shuster , G , Pohle , R , Kashanin , D , Klemm , R , Ikonen , V , Mezmale , L , Broza , Y Y , Shani , G & Haick , H 2021 , ' Sensing gastric cancer via point‐of‐care sensor breath analyzer ' , Cancer , vol. 127 , no. 8 , pp. 1286-1292 . https://doi.org/10.1002/cncr.33437, Issue 2, 2021, Page(s) 1286-1292, ISSN 1097-0142
Publisher: Cancer
DOI: 10.1002/cncr.33437

An eNose-based method performing drift correction for online VOC detection under dry and humid conditions (opens in new window)

Author(s): Carsten Jaeschke, Johannes Glöckler, Marta Padilla, Jan Mitrovics, Boris Mizaikoff
Published in: Analytical Methods, Issue 12, 2020, Page(s) 4724-4733, ISSN 1759-9679
Publisher: Royal society of chemistry
DOI: 10.1039/d0ay01172j

The Volatilomic Footprints of Human HGC-27 and CLS-145 Gastric Cancer Cell Lines (opens in new window)

Author(s): Andreas Leiherer, Daria Ślefarska, Marcis Leja, Christine Heinzle, Axel Mündlein, Ilze Kikuste, Linda Mezmale, Heinz Drexel, Chris A. Mayhew, Paweł Mochalski
Published in: Frontiers in Molecular Biosciences, Issue 7, 2021, Page(s) 607904, ISSN 2296-889X
Publisher: Frontiers in Molecular Biosciences
DOI: 10.3389/fmolb.2020.607904

Modular Breath Analyzer (MBA): Introduction of a Breath Analyzer Platform Based on an Innovative and Unique, Modular eNose Concept for Breath Diagnostics and Utilization of Calibration Transfer Methods in Breath Analysis Studies (opens in new window)

Author(s): Carsten Jaeschke, Marta Padilla, Johannes Glöckler, Inese Polaka, Martins Leja, Viktors Veliks, Jan Mitrovics, Marcis Leja, Boris Mizaikoff
Published in: Molecules, Issue 3776, 2021, Page(s) 12, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules26123776

iHWG-MOX: A Hybrid Breath Analysis System via the Combination of Substrate-Integrated Hollow Waveguide Infrared Spectroscopy with Metal Oxide Gas Sensors (opens in new window)

Author(s): Johannes Glöckler, Carsten Jaeschke, Yusuf Kocaöz, Vjekoslav Kokoric, Erhan Tütüncü, Jan Mitrovics, and Boris Mizaikoff
Published in: ACS Sensors, Issue 5, 2020, Page(s) 1033-1039, ISSN 2379-3694
Publisher: American Chemical Society (ACS)
DOI: 10.1021/acssensors.9b02554

Outside front cover: From Light Pipes to Substrate-Integrated Hollow Waveguides for Gas Sensing: A Review

Author(s): Diandra Nunes Barreto, Vjekoslav Kokoric, JoãoFlávio da Silveira Petruci, and Boris Mizaikof
Published in: ACS Measurement Science Au, Issue 1, 2021, Page(s) 97-109, ISSN 2694-250X
Publisher: American Chemical Society

How do international gastric cancer prevention guidelines influence clinical practice globally? (opens in new window)

Author(s): Evita Gasenko, Marcis Leja, Inese Polaka, Alinta Hegmane, Raul Murillo, Dmitry Bordin, Alexander Link, Minna Kulju, Pawel Mochalski, Gidi Shani, Peter Malfertheiner, Rolando Herrero, Hossam Haick
Published in: European Journal of Cancer Prevention, Issue 29/5, 2020, Page(s) 400-407, ISSN 0959-8278
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/cej.0000000000000580

Volatile Compounds Are Involved in Cellular Crosstalk and Upregulation (opens in new window)

Author(s): Mamatha Serasanambati, Yoav Y. Broza, Hossam Haick
Published in: Advanced Biosystems, Issue 3/10, 2019, Page(s) 1900131, ISSN 2366-7478
Publisher: Wiley
DOI: 10.1002/adbi.201900131

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