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BIOHYBRID AND BIODEGRADABLE NANOVACCINES FOR CANCER IMMUNOTHERAPY

Project description

The next generation of cancer vaccines

Nanotechnology has been used in a variety of biomedical applications including the delivery of drugs and immunotherapeutics. The EU-funded iNANOVAC4CANCER project has investigated the potential of using nanoparticles to develop vaccines against cancer. Researchers have tested various biodegradable nanoparticles coated with membranes from different types of cells as a means of evading immune responses. Nanovaccines have the potential to enhance cancer treatment efficacy by boosting tumour-specific immune responses and increasing the remission time. Importantly, they can be applied to all tumours and can be tailor-made to fit the patient profile.

Objective

The innovation of the biohybrid and biodegradable nanovaccines to be taken to proof-of-concept lies in the combination of different parts of the nanovaccine. A biohybrid and biodegradable nanovaccine shows potential to: (i) enhance cancer treatment efficacy; (ii) to be universally applicable to all cancers, regardless of the tumour in question; (iii) prolonging the survival rate of cancer patients; (iv) increase the amount of complete tumor remissions; and (v) boost of tumor-specific immune responses. This will allow in the future towards a personalized patient cancer therapy/treatment. More importantly, the applicability of biohybrid and biodegradable nanovaccines extends beyond the cancer treatment, as it can be applied for other type of diseases.

Fields of science (EuroSciVoc)

Programme(s)

Topic(s)

Funding Scheme

ERC-POC - Proof of Concept Grant

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Call for proposal

(opens in new window) ERC-2018-PoC

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Host institution

HELSINGIN YLIOPISTO
Net EU contribution
€ 150 000,00
Address
FABIANINKATU 33
00014 Helsinki
Finland
Region
Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa
Activity type
Higher or Secondary Education Establishments
Links
Total cost
€ 150 000,00

Beneficiaries (1)