ERA-NET to support the Joint Programming in Neurodegenerative Diseases strategic plan (JPND)

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Joint selection list of the projects to be funded

Procedures for public consultations on the JPND website

Call text and call documents

Web story, Supported project Fact Sheets, Interviews

Informal Interviews

Electronic submission tool

JPND website sections, including call-related information

Publications

Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans

Author(s): Marco Sazzini, Paolo Abondio, Stefania Sarno, Guido Alberto Gnecchi-Ruscone, Matteo Ragno, Cristina Giuliani, Sara De Fanti, Claudia Ojeda-Granados, Alessio Boattini, Julien Marquis, Armand Valsesia, Jerome Carayol, Frederic Raymond, Chiara Pirazzini, Elena Marasco, Alberto Ferrarini, Luciano Xumerle, Sebastiano Collino, Daniela Mari, Beatrice Arosio, Daniela Monti, Giuseppe Passarino, Patrizia D
Published in: BMC Biology, Issue 18, 2021, ISSN 1741-7007
Publisher: BioMed Central
DOI: 10.1186/s12915-020-00778-4

Plasma phosphorylated tau181 and neurodegeneration in Alzheimer’s disease

Author(s): Oskar Hansson, Nicholas Cullen, Henrik Zetterberg, null null, Kaj Blennow, Niklas Mattsson‐Carlgren
Published in: Annals of Clinical and Translational Neurology, Issue 8, 2023, Page(s) 259-265, ISSN 2328-9503
Publisher: WILEY
DOI: 10.1002/acn3.51253

The Role of Brain Integrity in the Association between Occupational Complexity and Cognitive Performance in Subjects with Increased Risk of Dementia

Author(s): Anders Rydström, Ruth Stephen, Ingemar Kåreholt, Alexander Darin Mattsson, Tiia Ngandu, Jenni Lehtisalo, Lars Bäckman, Nina Kemppainen, Juha Rinne, Shireen Sindi, Hilkka Soininen, Ritva Vanninen, Alina Solomon, Francesca Mangialasche
Published in: Gerontology, Issue 69, 2024, Page(s) 972-985, ISSN 0304-324X
Publisher: S. Karger AG
DOI: 10.1159/000530688

Neurofilament light levels predict clinical progression and death in multiple system atrophy

Author(s): Viorica Chelban, Elham Nikram, Alexandra Perez-Soriano, Carlo Wilke, Alexandra Foubert-Samier, Nirosen Vijiaratnam, Tong Guo, Edwin Jabbari, Simisola Olufodun, Mariel Gonzalez, Konstantin Senkevich, Brice Laurens, Patrice Péran, Olivier Rascol, Anne Pavy Le Traon, Emily G Todd, Alyssa A Costantini, Sondos Alikhwan, Ambreen Tariq, Bai Lin Ng, Esteban Muñoz, Celia Painous, Yaroslau Compta, Carme J
Published in: Brain, Issue 145, 2024, Page(s) 4398-4408, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awac253

Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms

Author(s): Arvid Edén, Anna Grahn, Daniel Bremell, Anahit Aghvanyan, Pradeepthi Bathala, Dietmar Fuchs, Johanna Gostner, Lars Hagberg, Nelly Kanberg, Sunsanee Kanjananimmanont, Magnus Lindh, Salvia Misaghian, Staffan Nilsson, Michael Schöll, George Sigal, Erika Stentoft, Marie Studahl, Aylin Yilmaz, Mingyue Wang, Martin Stengelin, Henrik Zetterberg, Magnus Gisslén
Published in: JAMA Network Open, Issue 5, 2024, Page(s) e2213253, ISSN 2574-3805
Publisher: AMER MEDICAL ASSOC
DOI: 10.1001/jamanetworkopen.2022.13253

Association between polygenic risk score of Alzheimer’s disease and plasma phosphorylated tau in individuals from the Alzheimer’s Disease Neuroimaging Initiative

Author(s): null null, Anna Zettergren, Jodie Lord, Nicholas J. Ashton, Andrea L. Benedet, Thomas K. Karikari, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Petroula Proitsi, Henrik Zetterberg, Kaj Blennow
Published in: Alzheimer's Research & Therapy, Issue 13, 2021, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-020-00754-8

Diagnostic Performance of Cerebrospinal Fluid Neurofilament Light Chain and Soluble Amyloid-β Protein Precursor β in the Subcortical Small Vessel Type of Dementia

Author(s): Elin Axelsson Andrén, Petronella Kettunen, Maria Bjerke, Sindre Rolstad, Henrik Zetterberg, Kaj Blennow, Anders Wallin, Johan Svensson
Published in: Journal of Alzheimer's Disease, Issue 96, 2024, Page(s) 1515-1528, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-230680

Neuroinflammation in Alzheimer disease

Author(s): Michael T. Heneka, Wiesje M. van der Flier, Frank Jessen, Jeroen Hoozemanns, Dietmar Rudolf Thal, Delphine Boche, Frederic Brosseron, Charlotte Teunissen, Henrik Zetterberg, Andreas H. Jacobs, Paul Edison, Alfredo Ramirez, Carlos Cruchaga, Jean-Charles Lambert, Agustin Ruiz Laza, Jose Vicente Sanchez-Mut, Andre Fischer, Sergio Castro-Gomez, Thor D. Stein, Luca Kleineidam, Michael Wagner, Jonas J.
Published in: Nature Reviews Immunology, 2024, ISSN 1474-1733
Publisher: Nature Publishing Group
DOI: 10.1038/s41577-024-01104-7

Exploring CSF neurofilament light as a biomarker for MS in clinical practice; a retrospective registry-based study

Author(s): Igal Rosenstein, Markus Axelsson, Lenka Novakova, Kaj Blennow, Henrik Zetterberg, Jan Lycke
Published in: Multiple Sclerosis Journal, Issue 28, 2025, Page(s) 872-884, ISSN 1352-4585
Publisher: SAGE Publications
DOI: 10.1177/13524585211039104

Establishment of reference values for plasma neurofilament light based on healthy individuals aged 5–90 years

Author(s): Joel Simrén, Ulf Andreasson, Johan Gobom, Marc Suarez Calvet, Barbara Borroni, Christopher Gillberg, Lars Nyberg, Roberta Ghidoni, Elisabeth Fernell, Mats Johnson, Herman Depypere, Caroline Hansson, Ingibjörg H Jonsdottir, Henrik Zetterberg, Kaj Blennow
Published in: Brain Communications, Issue 4, 2022, ISSN 2632-1297
Publisher: OXFORD UNIV PRESS
DOI: 10.1093/braincomms/fcac174

Social Health and Cognitive Change in Old Age: Role of Brain Reserve

Author(s): Anna Marseglia, Grégoria Kalpouzos, Erika J. Laukka, Jane Maddock, Praveetha Patalay, Hui‐Xin Wang, Lars Bäckman, Eric Westman, Anna‐Karin Welmer, Serhiy Dekhtyar, null null
Published in: Annals of Neurology, Issue 93, 2024, Page(s) 844-855, ISSN 0364-5134
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ana.26591

Hospital-treated infections in early- and mid-life and risk of Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis: A nationwide nested case-control study in Sweden

Author(s): Jiangwei Sun, Jonas F. Ludvigsson, Caroline Ingre, Fredrik Piehl, Karin Wirdefeldt, Ulrika Zagai, Weimin Ye, Fang Fang
Published in: PLOS Medicine, Issue 19, 2023, Page(s) e1004092, ISSN 1549-1676
Publisher: PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pmed.1004092

CSF biomarkers in patients with epilepsy in Alzheimer’s disease: a nation-wide study

Author(s): Rakesh Kumar Banote, Samuel Håkansson, Henrik Zetterberg, Johan Zelano
Published in: Brain Communications, Issue 4, 2022, ISSN 2632-1297
Publisher: OXFORD UNIV PRESS
DOI: 10.1093/braincomms/fcac210

Pitfalls of predicting age‐related traits by polygenic risk scores

Author(s): Valentina Escott‐Price, Karl Michael Schmidt
Published in: Annals of Human Genetics, Issue 87, 2023, Page(s) 203-209, ISSN 0003-4800
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ahg.12520

Anomia is present pre-symptomatically in frontotemporal dementia due to MAPT mutations

Author(s): Arabella Bouzigues, Lucy L. Russell, Georgia Peakman, Martina Bocchetta, Caroline V. Greaves, Rhian S. Convery, Emily Todd, James B. Rowe, Barbara Borroni, Daniela Galimberti, Pietro Tiraboschi, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Finger, John C. van Swieten, Harro Seelaar, Lize Jiskoot, Sandro Sorbi, Chris R. Butler, Caroline Graff, Alexander Gerhard, Tobias Langheinrich, Robert La
Published in: Journal of Neurology, Issue 269, 2022, Page(s) 4322-4332, ISSN 0340-5354
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-022-11068-0

Human Small Heat Shock Protein B8 Inhibits Protein Aggregation without Affecting the Native Folding Process

Author(s): Dhawal Choudhary, Laura Mediani, Mario J. Avellaneda, Sveinn Bjarnason, Simon Alberti, Edgar E. Boczek, Pétur O. Heidarsson, Alessandro Mossa, Serena Carra, Sander J. Tans, Ciro Cecconi
Published in: Journal of the American Chemical Society, Issue 145, 2023, Page(s) 15188-15196, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.3c02022

No increase of serum neurofilament light in relapsing-remitting multiple sclerosis patients switching from standard to extended-interval dosing of natalizumab

Author(s): Magnus Johnsson, Helen H Farman, Kaj Blennow, Henrik Zetterberg, Clas Malmeström, Markus Axelsson, Jan Lycke
Published in: Multiple Sclerosis Journal, Issue 28, 2025, Page(s) 2070-2080, ISSN 1352-4585
Publisher: SAGE Publications
DOI: 10.1177/13524585221108080

Role of Alkali Cations in DNA–Thioflavin T Interaction

Author(s): P. Hanczyc
Published in: The Journal of Physical Chemistry B, Issue 128, 2024, Page(s) 7520-7529, ISSN 1520-6106
Publisher: American Chemical Society
DOI: 10.1021/acs.jpcb.4c02417

Infections among individuals with multiple sclerosis, Alzheimer’s disease and Parkinson’s disease

Author(s): Yihan Hu, Kejia Hu, Huan Song, Yudi Pawitan, Fredrik Piehl, Fang Fang
Published in: Brain Communications, Issue 5, 2023, ISSN 2632-1297
Publisher: OXFORD UNIV PRESS
DOI: 10.1093/braincomms/fcad065

Developing consensus description of group music therapy characteristics for persons with dementia

Author(s): Sarah I. M. Janus, Annemieke C. Vink, Hanne Mette Ridder, Monika Geretsegger, Brynjulf Stige, Christian Gold, Sytse U. Zuidema
Published in: Nordic Journal of Music Therapy, Issue 30, 2021, Page(s) 24-40, ISSN 0809-8131
Publisher: Sogn and Fjordane University College
DOI: 10.1080/08098131.2020.1779790

C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons

Author(s): Paolo M Marchi, Lara Marrone, Laurent Brasseur, Audrey Coens, Christopher P Webster, Luc Bousset, Marco Destro, Emma F Smith, Christa G Walther, Victor Alfred, Raffaele Marroccella, Emily J Graves, Darren Robinson, Allan C Shaw, Lai Mei Wan, Andrew J Grierson, Stephen J Ebbens, Kurt J De Vos, Guillaume M Hautbergue, Laura Ferraiuolo, Ronald Melki, Mimoun Azzouz
Published in: Life Science Alliance, Issue 5, 2024, Page(s) e202101276, ISSN 2575-1077
Publisher: The Rockefeller University Press, NEW YORK
DOI: 10.26508/lsa.202101276

Ten years of image analysis and machine learning competitions in dementia

Author(s): Esther E. Bron, Stefan Klein, Annika Reinke, Janne M. Papma, Lena Maier-Hein, Daniel C. Alexander, Neil P. Oxtoby
Published in: NeuroImage, Issue 253, 2024, Page(s) 119083, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2022.119083

Multimodal Preventive Trial for Alzheimer's Disease: MIND-ADmini Pilot Trial Study Design and Progress

Author(s): S. Sindi, C. Thunborg, A. Rosenberg, P. Andersen, S. Andrieu, L.M. Broersen, N. Coley, C. Couderc, C.Z. Duval, G. Faxen-Irving, G. Hagman, M. Hallikainen, K. Håkansson, J. Lehtisalo, N. Levak, F. Mangialasche, J. Pantel, E. Kekkonen, A. Rydström, A. Stigsdotter-Neely, A. Wimo, T. Ngandu, H. Soininen, T. Hartmann, A. Solomon, Miia Kivipelto
Published in: The Journal of Prevention of Alzheimer's Disease, Issue 9, 2025, Page(s) 30-39, ISSN 2274-5807
Publisher: SPRINGER BASEL AG
DOI: 10.14283/jpad.2022.4

A genome-wide association study of plasma phosphorylated tau181

Author(s): Jodie Lord, Anna Zettergren, Nicholas J. Ashton, Thomas K. Karikari, Andrea L. Benedet, Joel Simrén, Abdul Hye, Dag Aarsland, Kaj Blennow, Henrik Zetterberg, Petroula Proitsi
Published in: Neurobiology of Aging, Issue 106, 2022, Page(s) 304.e1-304.e3, ISSN 0197-4580
Publisher: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2021.04.018

Comprehensive short and long read sequencing analysis for the Gaucher and Parkinson’s disease-associated GBA gene

Author(s): Marco Toffoli, Xiao Chen, Fritz J. Sedlazeck, Chiao-Yin Lee, Stephen Mullin, Abigail Higgins, Sofia Koletsi, Monica Emili Garcia-Segura, Esther Sammler, Sonja W. Scholz, Anthony H. V. Schapira, Michael A. Eberle, Christos Proukakis
Published in: Communications Biology, Issue 5, 2022, ISSN 2399-3642
Publisher: SPRINGER NATURE
DOI: 10.1038/s42003-022-03610-7

Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer’s Disease: A Randomized Controlled Trial—The OmegAD Study

Author(s): Avin Tofiq, Henrik Zetterberg, Kaj Blennow, Hans Basun, Tommy Cederholm, Maria Eriksdotter, Gerd Faxén-Irving, Erik Hjorth, Fredrik Jernerén, Marianne Schultzberg, Lars-Olof Wahlund, Jan Palmblad, Yvonne Freund-Levi
Published in: Journal of Alzheimer's Disease, Issue 83, 2024, Page(s) 1291-1301, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-210007

Circulating Brain-Injury Markers After Surgery for Craniosynostosis

Author(s): Isak Michaëlsson, Thomas Skoglund, Tobias Hallén, Robert Olsson, Giovanni Maltese, Peter Tarnow, Madiha Bhatti-Søfteland, Henrik Zetterberg, Kaj Blennow, Lars Kölby
Published in: World Neurosurgery, Issue 173, 2024, Page(s) e593-e599, ISSN 1878-8750
Publisher: Elsevier BV
DOI: 10.1016/j.wneu.2023.02.102

Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain

Author(s): Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-45192-4

Association of Serum Brain-Derived Tau With Clinical Outcome and Longitudinal Change in Patients With Severe Traumatic Brain Injury

Author(s): Fernando Gonzalez-Ortiz, Maciej Dulewicz, Nicholas J. Ashton, Przemysław R. Kac, Henrik Zetterberg, Emma Andersson, Yara Yakoub, Jörg Hanrieder, Michael Turton, Peter Harrison, Bengt Nellgård, Thomas K. Karikari, Kaj Blennow
Published in: JAMA Network Open, Issue 6, 2023, Page(s) e2321554, ISSN 2574-3805
Publisher: AMER MEDICAL ASSOC
DOI: 10.1001/jamanetworkopen.2023.21554

Plasma and CSF NfL are differentially associated with biomarker evidence of neurodegeneration in a community‐based sample of 70‐year‐olds

Author(s): Anna Dittrich, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Joel Simrén, Fiona Geiger, Anna Zettergren, Sara Shams, Alejandra Machado, Eric Westman, Michael Schöll, Ingmar Skoog, Silke Kern
Published in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Issue 14, 2023, ISSN 2352-8729
Publisher: WILEY
DOI: 10.1002/dad2.12295

Dementia prevention in memory clinics: recommendations from the European task force for brain health services

Author(s): Giovanni B. Frisoni, Daniele Altomare, Federica Ribaldi, Nicolas Villain, Carol Brayne, Naaheed Mukadam, Marc Abramowicz, Frederik Barkhof, Marcelo Berthier, Melanie Bieler-Aeschlimann, Kaj Blennow, Andrea Brioschi Guevara, Emmanuel Carrera, Gaël Chételat, Chantal Csajka, Jean-François Demonet, Alessandra Dodich, Valentina Garibotto, Jean Georges, Samia Hurst, Frank Jessen, Miia Kivipelto, Davi
Published in: The Lancet Regional Health - Europe, Issue 26, 2023, Page(s) 100576, ISSN 2666-7762
Publisher: The Lancet Regional Health - Europe
DOI: 10.1016/j.lanepe.2022.100576

Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development

Author(s): Tereza Vanova, Jiri Sedmik, Jan Raska, Katerina Amruz Cerna, Petr Taus, Veronika Pospisilova, Marketa Nezvedova, Veronika Fedorova, Sona Kadakova, Hana Klimova, Michaela Capandova, Petra Orviska, Petr Fojtik, Simona Bartova, Karla Plevova, Zdenek Spacil, Hana Hribkova, Dasa Bohaciakova
Published in: Cell Reports, Issue 42, 2024, Page(s) 113310, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2023.113310

CSF biomarkers and plasma p‐tau181 as predictors of longitudinal tau accumulation: Implications for clinical trial design

Author(s): Alexis Moscoso, Thomas K. Karikari, Michel J. Grothe, Nicholas J. Ashton, Juan Lantero‐Rodriguez, Anniina Snellman, Henrik Zetterberg, Kaj Blennow, Michael Schöll
Published in: Alzheimer's & Dementia, Issue 18, 2023, Page(s) 2614-2626, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12570

Motor symptoms in genetic frontotemporal dementia: developing a new module for clinical rating scales

Author(s): Kiran Samra, Amy M. MacDougall, Georgia Peakman, Arabella Bouzigues, Martina Bocchetta, David M. Cash, Caroline V. Greaves, Rhian S. Convery, John C. van Swieten, Lize Jiskoot, Harro Seelaar, Fermin Moreno, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Mario Masellis, Carmela Tartaglia, James B. Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe
Published in: Journal of Neurology, Issue 270, 2023, Page(s) 1466-1477, ISSN 0340-5354
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-022-11442-y

Antibody-free measurement of cerebrospinal fluid tau phosphorylation across the Alzheimer’s disease continuum

Author(s): Johan Gobom, Andréa L. Benedet, Niklas Mattsson-Carlgren, Laia Montoliu-Gaya, Nina Schultz, Nicholas J. Ashton, Shorena Janelidze, Stijn Servaes, Mathias Sauer, Tharick A. Pascoal, Thomas K. Karikari, Juan Lantero-Rodriguez, Gunnar Brinkmalm, Henrik Zetterberg, Oskar Hansson, Pedro Rosa-Neto, Kaj Blennow
Published in: Molecular Neurodegeneration, Issue 17, 2022, ISSN 1750-1326
Publisher: BioMed Central
DOI: 10.1186/s13024-022-00586-0

DreaMR: Diffusion-driven Counterfactual Explanation for Functional MRI

Author(s): Hasan A. Bedel, Tolga Çukur
Published in: IEEE Transactions on Medical Imaging, 2024, Page(s) 1-1, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2024.3507008

Microglia and amyloid plaque formation in Alzheimer's disease – Evidence, possible mechanisms, and future challenges

Author(s): Stefanie Fruhwürth, Henrik Zetterberg, Søren R. Paludan
Published in: Journal of Neuroimmunology, Issue 390, 2024, Page(s) 578342, ISSN 0165-5728
Publisher: Elsevier BV
DOI: 10.1016/j.jneuroim.2024.578342

Resource assessment in trials undertaken in residential care homes: Experiences from the Australian MIDDEL cluster randomised controlled trial research team

Author(s): Felicity A. Baker, Phoebe A. Stretton-Smith, Tanara Vieira Sousa, Imogen Clark, Alice Cotton, Christian Gold, Young-Eun C. Lee
Published in: Contemporary Clinical Trials Communications, Issue 20, 2020, Page(s) 100675, ISSN 2451-8654
Publisher: Elsevier
DOI: 10.1016/j.conctc.2020.100675

Book of Abstracts ESMRMB 2024 Online 40th Annual Scientific Meeting 2–5 October 2024

Author(s): Cetin AI, Turhan G, Padrela BE, Mahroo A, Konstandin S, Hoinkiss DC, Breutigam NJ, Keil V, Barkhof F, Danyeli AE, Ozduman K, Pamir MN, Eickel K, Mutsaerts HJMM, Petr J, Guenther M, Dincer A, Ozturk-Isik E
Published in: Magnetic Resonance Materials in Physics, Biology and Medicine, Issue 37, 2024, Page(s) 1-781, ISSN 1352-8661
Publisher: Springer
DOI: 10.1007/s10334-024-01191-6

Fluid Biomarkers for Synaptic Dysfunction and Loss

Author(s): Elena Camporesi, Johanna Nilsson, Ann Brinkmalm, Bruno Becker, Nicholas J Ashton, Kaj Blennow, Henrik Zetterberg
Published in: Biomarker Insights, Issue 15, 2025, Page(s) 117727192095031, ISSN 1177-2719
Publisher: Libertas Academica
DOI: 10.1177/1177271920950319

Cerebrospinal fluid brevican and neurocan fragment patterns in human traumatic brain injury

Author(s): Karolina Minta, Gunnar Brinkmalm, Eric P. Thelin, Faiez Al Nimer, Fredrik Piehl, Mats Tullberg, Anna Jeppsson, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Ulf Andreasson
Published in: Clinica Chimica Acta, Issue 512, 2021, Page(s) 74-83, ISSN 0009-8981
Publisher: Elsevier BV
DOI: 10.1016/j.cca.2020.11.017

Alzheimer’s disease-associated complement gene variants influence plasma complement protein levels

Author(s): Aurora Veteleanu, Joshua Stevenson-Hoare, Samuel Keat, Nikoleta Daskoulidou, Henrik Zetterberg, Amanda Heslegrave, Valentina Escott-Price, Julie Williams, Rebecca Sims, Wioleta M. Zelek, Sarah M. Carpanini, Bryan Paul Morgan
Published in: Journal of Neuroinflammation, Issue 20, 2023, ISSN 1742-2094
Publisher: BioMed Central
DOI: 10.1186/s12974-023-02850-6

Frailty trajectories in three longitudinal studies of aging: Is the level or the rate of change more predictive of mortality?

Author(s): Ge Bai, Agnieszka Szwajda, Yunzhang Wang, Xia Li, Hannah Bower, Ida K Karlsson, Boo Johansson, Anna K Dahl Aslan, Nancy L Pedersen, Sara Hägg, Juulia Jylhävä
Published in: Age and Ageing, Issue 50, 2021, Page(s) 2174-2182, ISSN 0002-0729
Publisher: Oxford University Press
DOI: 10.1093/ageing/afab106

Plasma neurofilament light chain levels predict improvement in late phase after stroke

Author(s): Anna Stokowska, Lina Bunketorp Käll, Christian Blomstrand, Joel Simrén, Michael Nilsson, Henrik Zetterberg, Kaj Blennow, Milos Pekny, Marcela Pekna
Published in: European Journal of Neurology, Issue 28, 2023, Page(s) 2218-2228, ISSN 1351-5101
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ene.14854

A guide for blood–brain barrier models

Author(s): Yomna Soliman, Jana Al‐khodor, Gülnaz Yildirim Köken, Nur Mustafaoglu
Published in: FEBS Letters, Issue 599, 2025, Page(s) 599-644, ISSN 0014-5793
Publisher: Elsevier BV
DOI: 10.1002/1873-3468.15053

Addition of the FTD Module to the Neuropsychiatric Inventory improves classification of frontotemporal dementia spectrum disorders

Author(s): Lize C. Jiskoot, Lucy L. Russell, Caroline V. Greaves, Esther van Schaik, Esther van den Berg, Jackie M. Poos, Liset de Boer, Laura Donker Kaat, Harro Seelaar, Yolande A. L. Pijnenburg, John C. van Swieten, Jonathan D. Rohrer
Published in: Journal of Neurology, Issue 270, 2023, Page(s) 2674-2687, ISSN 0340-5354
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-023-11596-3

Clinical effectiveness of music interventions for dementia and depression in elderly care (MIDDEL): Australian cohort of an international pragmatic cluster-randomised controlled trial

Author(s): Felicity A Baker, Young-Eun C Lee, Tanara Vieira Sousa, Phoebe A Stretton-Smith, Jeanette Tamplin, Vigdis Sveinsdottir, Monika Geretsegger, Jo Dugstad Wake, Jörg Assmus, Christian Gold
Published in: The Lancet Healthy Longevity, Issue 3, 2024, Page(s) e153-e165, ISSN 2666-7568
Publisher: ELSEVIER
DOI: 10.1016/s2666-7568(22)00027-7

Prediction of future Alzheimer’s disease dementia using plasma phospho-tau combined with other accessible measures

Author(s): Sebastian Palmqvist, Pontus Tideman, Nicholas Cullen, Henrik Zetterberg, Kaj Blennow, null null, Jeffery L. Dage, Erik Stomrud, Shorena Janelidze, Niklas Mattsson-Carlgren, Oskar Hansson
Published in: Nature Medicine, Issue 27, 2023, Page(s) 1034-1042, ISSN 1078-8956
Publisher: Nature Publishing Group
DOI: 10.1038/s41591-021-01348-z

Blood-based biomarkers for Alzheimer's disease: towards clinical implementation

Author(s): Charlotte E Teunissen, Inge M W Verberk, Elisabeth H Thijssen, Lisa Vermunt, Oskar Hansson, Henrik Zetterberg, Wiesje M van der Flier, Michelle M Mielke, Marta del Campo
Published in: The Lancet Neurology, Issue 21, 2023, Page(s) 66-77, ISSN 1474-4422
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1474-4422(21)00361-6

Clinical performance and head-to-head comparison of CSF p-tau235 with p-tau181, p-tau217 and p-tau231 in two memory clinic cohorts

Author(s): Juan Lantero-Rodriguez, Agathe Vrillon, Aida Fernández-Lebrero, Paula Ortiz-Romero, Anniina Snellman, Laia Montoliu-Gaya, Wagner S. Brum, Emmanuel Cognat, Julien Dumurgier, Albert Puig-Pijoan, Irene Navalpotro-Gómez, Greta García-Escobar, Thomas K. Karikari, Eugeen Vanmechelen, Nicholas J. Ashton, Henrik Zetterberg, Marc Suárez-Calvet, Claire Paquet, Kaj Blennow
Published in: Alzheimer's Research & Therapy, Issue 15, 2023, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-023-01201-0

Plasma protein profiling reveals novel specific biomarkers reflecting the multifactorial nature of Alzheimer´s disease continuum

Author(s): Giovanni Bellomo, Sjors G.J.G. in ’t Veld, James D Doecke, Carlos Quesada, Lisa Vermunt, Daniel Alcolea, Steffen Halbgebauer, Niklas Mattsson‐Carlgren, Katerina Veverova, Lynn Boonkamp, Yanaika S. Hok‐A‐Hin, Christopher J Fowler, Juan Fortea, Lorenzo Gaetani, Andrea Toja, Yolande A.L. Pijnenburg, Afina W. Lemstra, Wiesje M. van der Flier, Jakub Hort, Markus Otto, Oskar Hansson, Colin L Mas
Published in: Alzheimer's & Dementia, Issue 19, 2024, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.074777

A Western‐style dietary pattern is associated with cerebrospinal fluid biomarker levels for preclinical Alzheimer's disease—A population‐based cross‐sectional study among 70‐year‐olds

Author(s): Jessica Samuelsson, Silke Kern, Henrik Zetterberg, Kaj Blennow, Elisabet Rothenberg, Ola Wallengren, Ingmar Skoog, Anna Zettergren
Published in: Alzheimer's & Dementia: Translational Research & Clinical Interventions, Issue 7, 2023, ISSN 2352-8737
Publisher: WILEY
DOI: 10.1002/trc2.12183

What does heritability of Alzheimer’s disease represent?

Author(s): Emily Baker, Ganna Leonenko, Karl Michael Schmidt, Matthew Hill, Amanda J. Myers, Maryam Shoai, Itziar de Rojas, Niccoló Tesi, Henne Holstege, Wiesje M. van der Flier, Yolande A. L. Pijnenburg, Agustin Ruiz, John Hardy, Sven van der Lee, Valentina Escott-Price
Published in: PLOS ONE, Issue 18, 2023, Page(s) e0281440, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0281440

Stratifying the Presymptomatic Phase of Genetic Frontotemporal Dementia by Serum<scp>NfL</scp>and<scp>pNfH</scp>: A Longitudinal Multicentre Study

Author(s): Carlo Wilke, Selina Reich, John C. van Swieten, Barbara Borroni, Raquel Sanchez‐Valle, Fermin Moreno, Robert Laforce, Caroline Graff, Daniela Galimberti, James B. Rowe, Mario Masellis, Maria C. Tartaglia, Elizabeth Finger, Rik Vandenberghe, Alexandre de Mendonça, Fabrizio Tagliavini, Isabel Santana, Simon Ducharme, Chris R. Butler, Alexander Gerhard, Johannes Levin, Adrian Danek, Markus Otto, G
Published in: Annals of Neurology, Issue 91, 2024, Page(s) 33-47, ISSN 0364-5134
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ana.26265

Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative

Author(s): Thomas K. Karikari, Andréa L. Benedet, Nicholas J. Ashton, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Paramita Saha-Chaudhuri, Firoza Lussier, Hlin Kvartsberg, Alexis Moscoso Rial, Tharick A. Pascoal, Ulf Andreasson, Michael Schöll, Michael W. Weiner, Pedro Rosa-Neto, John Q. Trojanowski, Leslie M. Shaw, Kaj Blennow, Henrik Zetterberg, null null
Published in: Molecular Psychiatry, Issue 26, 2022, Page(s) 429-442, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-020-00923-z

TDP-43 proteinopathies: a new wave of neurodegenerative diseases

Author(s): Eva Maria Johanna de Boer, Viyanti K Orie, Timothy Williams, Mark R Baker, Hugo M De Oliveira, Tuomo Polvikoski, Matthew Silsby, Parvathi Menon, Mehdi van den Bos, Glenda M Halliday, Leonard H van den Berg, Ludo Van Den Bosch, Philip van Damme, Matthew C Kiernan, Michael A van Es, Steve Vucic
Published in: Journal of Neurology, Neurosurgery & Psychiatry, Issue 92, 2023, Page(s) 86-95, ISSN 0022-3050
Publisher: BMJ Publishing Group
DOI: 10.1136/jnnp-2020-322983

New cases of dementia are rising in elderly populations in Wales, UK

Author(s): Joshua Stevenson-Hoare, Ann-Kathrin Schalkamp, Cynthia Sandor, John Hardy, Valentina Escott-Price
Published in: Journal of the Neurological Sciences, Issue 451, 2024, Page(s) 120715, ISSN 0022-510X
Publisher: Elsevier BV
DOI: 10.1016/j.jns.2023.120715

Transient Changes in the Plasma of Astrocytic and Neuronal Injury Biomarkers in COVID-19 Patients without Neurological Syndromes

Author(s): Matthew P. Lennol, Nicholas J. Ashton, Oscar Moreno-Pérez, María-Salud García-Ayllón, Jose-Manuel Ramos-Rincon, Mariano Andrés, José-Manuel León-Ramírez, Vicente Boix, Joan Gil, Kaj Blennow, Esperanza Merino, Henrik Zetterberg, Javier Sáez-Valero
Published in: International Journal of Molecular Sciences, Issue 24, 2025, Page(s) 2715, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24032715

Central nervous system monoaminergic activity in hip osteoarthritis patients with disabling pain: associations with pain severity and central sensitization

Author(s): Martin F. Bjurström, Kaj Blennow, Henrik Zetterberg, Mikael Bodelsson, Markus Waldén, Nicholas Dietz, Sara Hall, Oskar Hansson, Michael R. Irwin, Niklas Mattsson-Carlgren
Published in: PAIN Reports, Issue 7, 2024, Page(s) e988, ISSN 2471-2531
Publisher: LIPPINCOTWILLIAMS & WILKINS
DOI: 10.1097/pr9.0000000000000988

Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling

Author(s): Luana Naia, Catarina M. Pinho, Giacomo Dentoni, Jianping Liu, Nuno Santos Leal, Duarte M. S. Ferreira, Bernadette Schreiner, Riccardo Filadi, Lígia Fão, Niamh M. C. Connolly, Pontus Forsell, Gunnar Nordvall, Makoto Shimozawa, Elisa Greotti, Emy Basso, Pierre Theurey, Anna Gioran, Alvin Joselin, Marie Arsenian-Henriksson, Per Nilsson, A. Cristina Rego, Jorge L. Ruas, David Park, Daniele Bano, Pao
Published in: BMC Biology, Issue 19, 2021, ISSN 1741-7007
Publisher: BioMed Central
DOI: 10.1186/s12915-021-00979-5

Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer’s disease neuropathology

Author(s): Przemysław R. Kac, Fernando González-Ortiz, Andreja Emeršič, Maciej Dulewicz, Srinivas Koutarapu, Michael Turton, Yang An, Denis Smirnov, Agnieszka Kulczyńska-Przybik, Vijay R. Varma, Nicholas J. Ashton, Laia Montoliu-Gaya, Elena Camporesi, Izabela Winkel, Bogusław Paradowski, Abhay Moghekar, Juan C. Troncoso, Tammaryn Lashley, Gunnar Brinkmalm, Susan M. Resnick, Barbara Mroczko, Hlin Kvarts
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-46876-7

Predicting neurological outcome after out-of-hospital cardiac arrest with cumulative information; development and internal validation of an artificial neural network algorithm

Author(s): Peder Andersson, Jesper Johnsson, Ola Björnsson, Tobias Cronberg, Christian Hassager, Henrik Zetterberg, Pascal Stammet, Johan Undén, Jesper Kjaergaard, Hans Friberg, Kaj Blennow, Gisela Lilja, Matt P. Wise, Josef Dankiewicz, Niklas Nielsen, Attila Frigyesi
Published in: Critical Care, Issue 25, 2021, ISSN 1364-8535
Publisher: BMC
DOI: 10.1186/s13054-021-03505-9

Characterization of pre‐analytical sample handling effects on a panel of Alzheimer's disease–related blood‐based biomarkers: Results from the Standardization of Alzheimer's Blood Biomarkers (SABB) working group

Author(s): Inge M. W. Verberk, Els O. Misdorp, Jannet Koelewijn, Andrew J. Ball, Kaj Blennow, Jeffrey L. Dage, Noelia Fandos, Oskar Hansson, Christophe Hirtz, Shorena Janelidze, Sungmin Kang, Kristopher Kirmess, Jana Kindermans, Ryan Lee, Matthew R. Meyer, Dandan Shan, Leslie M. Shaw, Teresa Waligorska, Tim West, Henrik Zetterberg, Rebecca M. Edelmayer, Charlotte E. Teunissen
Published in: Alzheimer's & Dementia, Issue 18, 2023, Page(s) 1484-1497, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12510

Prevalence and Clinical Implications of a β-Amyloid–Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease

Author(s): Pontus Erickson, Joel Simrén, Wagner S. Brum, Gilda E. Ennis, Gwendlyn Kollmorgen, Ivonne Suridjan, Rebecca Langhough, Erin M. Jonaitis, Carol A. Van Hulle, Tobey J. Betthauser, Cynthia M. Carlsson, Sanjay Asthana, Nicholas J. Ashton, Sterling C. Johnson, Leslie M. Shaw, Kaj Blennow, Ulf Andreasson, Barbara B. Bendlin, Henrik Zetterberg, null null, Michael Weiner, Paul Aisen, Ronald Petersen, Cli
Published in: JAMA Neurology, Issue 80, 2023, Page(s) 969, ISSN 2168-6149
Publisher: American Medical Association
DOI: 10.1001/jamaneurol.2023.2338

α-Synuclein seed amplification assay as a diagnostic tool for parkinsonian disorders

Author(s): Bárbara Fernandes Gomes, Carly M. Farris, Yihua Ma, Luis Concha-Marambio, Russ Lebovitz, Bengt Nellgård, Keti Dalla, Julius Constantinescu, Radu Constantinescu, Johan Gobom, Ulf Andreasson, Henrik Zetterberg, Kaj Blennow
Published in: Parkinsonism & Related Disorders, Issue 117, 2023, Page(s) 105807, ISSN 1353-8020
Publisher: Elsevier BV
DOI: 10.1016/j.parkreldis.2023.105807

Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services—part 4 of 6

Author(s): Alina Solomon, Ruth Stephen, Daniele Altomare, Emmanuel Carrera, Giovanni B. Frisoni, Jenni Kulmala, José Luis Molinuevo, Peter Nilsson, Tiia Ngandu, Federica Ribaldi, Bruno Vellas, Philip Scheltens, Miia Kivipelto, null null, Marc Abramowicz, Daniele Altomare, Frederik Barkhof, Marcelo Berthier, Melanie Bieler, Kaj Blennow, Carol Brayne, Andrea Brioschi, Emmanuel Carrera, Gael Chételat, Chantal
Published in: Alzheimer's Research & Therapy, Issue 13, 2021, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-021-00875-8

Molecular Structure of Cu(II)-Bound Amyloid-β Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer’s Disease

Author(s): Axel Abelein, Simone Ciofi-Baffoni, Cecilia Mörman, Rakesh Kumar, Andrea Giachetti, Mario Piccioli, Henrik Biverstål
Published in: JACS Au, Issue 2, 2023, Page(s) 2571-2584, ISSN 2691-3704
Publisher: AMER CHEMICAL SOC
DOI: 10.1021/jacsau.2c00438

What do data‐driven Alzheimer’s disease subtypes tell us about white matter pathology and clinical progression?

Author(s): Hanyi Chen, Eric de Silva, Carole H Sudre, Jo Barnes, Alexandra L. Young, Neil P. Oxtoby, Frederik Barkhof, Daniel C. Alexander, Andre Altmann
Published in: Alzheimer's & Dementia, Issue 17, 2023, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.054028

Sixteen-Year Longitudinal Evaluation of Blood-Based DNA Methylation Biomarkers for Early Prediction of Alzheimer’s Disease

Author(s): Fernanda Schäfer Hackenhaar, null null, Maria Josefsson, Annelie Nordin Adolfsson, Mattias Landfors, Karolina Kauppi, Tenielle Porter, Lidija Milicic, Simon M. Laws, Magnus Hultdin, Rolf Adolfsson, Sofie Degerman, Sara Pudas
Published in: Journal of Alzheimer's Disease, Issue 94, 2024, Page(s) 1443-1464, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-230039

Cerebrospinal fluid markers of inflammation and brain injury in Lyme neuroborreliosis – a prospective follow-up study

Author(s): Ivar Tjernberg, Paula Gyllemark, Henrik Zetterberg, Kaj Blennow, Jan Ernerudh, Pia Forsberg, Johanna Sjöwall, Anna J. Henningsson
Published in: Clinical Chemistry and Laboratory Medicine (CCLM), Issue 60, 2023, Page(s) 1124-1132, ISSN 1434-6621
Publisher: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/cclm-2022-0097

Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation

Author(s): Laura Torres-Garcia, Joana M. P. Domingues, Edoardo Brandi, Caroline Haikal, Janitha M. Mudannayake, Inês C. Brás, Ellen Gerhardt, Wen Li, Alexander Svanbergsson, Tiago F. Outeiro, Gunnar K. Gouras, Jia-Yi Li
Published in: Scientific Reports, Issue 12, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-06846-9

Health status and risk profiles for brain aging of rural‐dwelling older adults: Data from the interdisciplinary baseline assessments in MIND‐China

Author(s): Yongxiang Wang, Xiaolei Han, Xianda Zhang, Zhonglin Zhang, Lin Cong, Shi Tang, Tingting Hou, Cuicui Liu, Xiaojuan Han, Qinghua Zhang, Jianli Feng, Ling Yin, Lin Song, Yi Dong, Rui Liu, Yuanjing Li, Tiia Ngandu, Miia Kivipelto, Heather Snyder, Maria Carrillo, Jonas Persson, Laura Fratiglioni, Lenore J Launer, Jianping Jia, Yifeng Du, Chengxuan Qiu
Published in: Alzheimer's & Dementia: Translational Research & Clinical Interventions, Issue 8, 2024, ISSN 2352-8737
Publisher: WILEY
DOI: 10.1002/trc2.12254

Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease

Author(s): Alexis Moscoso, Michel J. Grothe, Nicholas J. Ashton, Thomas K. Karikari, Juan Lantero Rodríguez, Anniina Snellman, Marc Suárez-Calvet, Kaj Blennow, Henrik Zetterberg, Michael Schöll, null null, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, Jr., William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw,
Published in: JAMA Neurology, Issue 78, 2022, Page(s) 396, ISSN 2168-6149
Publisher: American Medical Association
DOI: 10.1001/jamaneurol.2020.4986

Attitudes of at-risk older adults about prevention of cardiovascular disease and dementia using eHealth: a qualitative study in a European context

Author(s): Ulrika Akenine, Mariagnese Barbera, Cathrien RL Beishuizen, Mandana Fallah Pour, Juliette Guillemont, Anna Rosenberg, Nicola Coley, Francesca Mangialasche, Lotta Salo, Stephanie Savy, A Jeannette Pols, Sandrine Andrieu, Edo Richard, Hilkka Soininen, Eric Moll van Charante, Miia Kivipelto
Published in: BMJ Open, Issue 10, 2023, Page(s) e037050, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2020-037050

Compliance with National and International Guidelines in the Treatment of Nonmotor Symptoms in Late-Stage Parkinson’s Disease

Author(s): Kristina Rosqvist, Per Odin
Published in: Parkinson's Disease, Issue 2023, 2023, Page(s) 1-11, ISSN 2042-0080
Publisher: Hindawi Publishing Corporation
DOI: 10.1155/2023/6667339

A Plug-In Graph Neural Network to Boost Temporal Sensitivity in fMRI Analysis

Author(s): Irmak Sivgin, Hasan Atakan Bedel, Saban Ozturk, Tolga Çukur
Published in: IEEE Journal of Biomedical and Health Informatics, Issue 28, 2024, Page(s) 5323-5334, ISSN 2168-2194
Publisher: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/jbhi.2024.3415000

A glycan epitope correlates with tau in serum and predicts progression to Alzheimer's disease in combination with APOE4 allele status

Author(s): Robin Ziyue Zhou, Davide Liborio Vetrano, Giulia Grande, Frida Duell, Linus Jönsson, Erika J Laukka, Claudia Fredolini, Bengt Winblad, Lars Tjernberg, Sophia Schedin‐Weiss
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 3244-3249, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13024

Dynamics of Selected Biomarkers in Cerebrospinal Fluid During Complex Endovascular Aortic Repair – A Pilot Study

Author(s): Gísli Gunnar Jónsson, Niklas Marklund, Kaj Blennow, Henrik Zetterberg, Anders Wanhainen, David Lindström, Jacob Eriksson, Kevin Mani
Published in: Annals of Vascular Surgery, Issue 78, 2023, Page(s) 141-151, ISSN 0890-5096
Publisher: Springer Verlag
DOI: 10.1016/j.avsg.2021.04.034

Comparison of long-term effects of metformin on longevity between people with type 2 diabetes and matched non-diabetic controls

Author(s): Joshua Stevenson-Hoare, Ganna Leonenko, Valentina Escott-Price
Published in: BMC Public Health, Issue 23, 2023, ISSN 1471-2458
Publisher: BioMed Central
DOI: 10.1186/s12889-023-15764-y

Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A consensus statement

Author(s): Harald Hegen, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa Maria Villar, Maria Alice V Willrich, Henrik Zetterberg, Florian Deisenhammer
Published in: Multiple Sclerosis Journal, Issue 29, 2025, Page(s) 182-195, ISSN 1352-4585
Publisher: SAGE Publications
DOI: 10.1177/13524585221134217

Plasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects

Author(s): Joana B Pereira, Shorena Janelidze, Erik Stomrud, Sebastian Palmqvist, Danielle van Westen, Jeffrey L Dage, Niklas Mattsson-Carlgren, Oskar Hansson
Published in: Brain, Issue 144, 2024, Page(s) 2826-2836, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awab163

Neurodegenerative disease of the brain: a survey of interdisciplinary approaches

Author(s): Franca Davenport, John Gallacher, Zoe Kourtzi, Ivan Koychev, Paul M. Matthews, Neil P. Oxtoby, Laura M. Parkes, Viola Priesemann, James B. Rowe, Stephen W. Smye, Henrik Zetterberg
Published in: Journal of The Royal Society Interface, Issue 20, 2023, ISSN 1742-5662
Publisher: ROYAL SOCIETY
DOI: 10.1098/rsif.2022.0406

Looking beneath the surface: the importance of subcortical structures in frontotemporal dementia

Author(s): Martina Bocchetta, Maura Malpetti, Emily G Todd, James B Rowe, Jonathan D Rohrer
Published in: Brain Communications, Issue 3, 2022, ISSN 2632-1297
Publisher: Oxford university press
DOI: 10.1093/braincomms/fcab158

No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington’s disease

Author(s): Ting-Ting Huang, Ruben Smith, Karl Bacos, Dong-Yan Song, Richard M. Faull, Henry J. Waldvogel, Jia-Yi Li
Published in: Acta Neuropathologica Communications, Issue 8, 2024, ISSN 2051-5960
Publisher: BioMed Central
DOI: 10.1186/s40478-020-00949-y

Decreased Electroencephalography Global Field Synchronization in Slow-Frequency Bands Characterizes Synaptic Dysfunction in Amnestic Subtypes of Mild Cognitive Impairment

Author(s): Una Smailovic, Daniel Ferreira, Birgitta Ausén, Nicholas James Ashton, Thomas Koenig, Henrik Zetterberg, Kaj Blennow, Vesna Jelic
Published in: Frontiers in Aging Neuroscience, Issue 14, 2022, ISSN 1663-4365
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnagi.2022.755454

Cerebrospinal fluid N-224 tau helps discriminate Alzheimer’s disease from subjective cognitive decline and other dementias

Author(s): Claudia Cicognola, Oskar Hansson, Philip Scheltens, Hlin Kvartsberg, Henrik Zetterberg, Charlotte E. Teunissen, Kaj Blennow
Published in: Alzheimer's Research & Therapy, Issue 13, 2021, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-020-00756-6

Synaptotagmin 13 is neuroprotective across motor neuron diseases

Author(s): M. Nizzardo, M. Taiana, F. Rizzo, J. Aguila Benitez, J. Nijssen, I. Allodi, V. Melzi, N. Bresolin, G. P. Comi, E. Hedlund, S. Corti
Published in: Acta Neuropathologica, Issue 139, 2021, Page(s) 837-853, ISSN 0001-6322
Publisher: Springer Verlag
DOI: 10.1007/s00401-020-02133-x

Reproductive period and preclinical cerebrospinal fluid markers for Alzheimer disease: a 25-year study

Author(s): Jenna Najar, Tore Hällström, Anna Zettergren, Lena Johansson, Erik Joas, Madeleine Mellqvist Fässberg, Henrik Zetterberg, Kaj Blennow, Silke Kern, Ingmar Skoog
Published in: Menopause, Issue 28, 2024, Page(s) 1099-1107, ISSN 1530-0374
Publisher: LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/gme.0000000000001816

ASIC-E4: Interplay of Beta-Amyloid, Synaptic Density and Neuroinflammation in Cognitively Normal Volunteers With Three Levels of Genetic Risk for Late-Onset Alzheimer's Disease – Study Protocol and Baseline Characteristics

Author(s): Anniina Snellman, Laura L. Ekblad, Mikko Koivumäki, Noora Lindgrén, Jouni Tuisku, Merja Perälä, Lila Kallio, Riina Lehtonen, Virva Saunavaara, Jani Saunavaara, Vesa Oikonen, Richard Aarnio, Eliisa Löyttyniemi, Riitta Parkkola, Mira Karrasch, Henrik Zetterberg, Kaj Blennow, Juha O. Rinne
Published in: Frontiers in Neurology, Issue 13, 2022, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2022.826423

Critical illness polyneuropathy, myopathy and neuronal biomarkers in COVID-19 patients: A prospective study

Author(s): Robert Frithiof, Elham Rostami, Eva Kumlien, Johan Virhammar, David Fällmar, Michael Hultström, Miklós Lipcsey, Nicholas Ashton, Kaj Blennow, Henrik Zetterberg, Anna Rostedt Punga
Published in: Clinical Neurophysiology, Issue 132, 2021, Page(s) 1733-1740, ISSN 1388-2457
Publisher: Elsevier BV
DOI: 10.1016/j.clinph.2021.03.016

Sleep disturbances and the speed of multimorbidity development in old age: results from a longitudinal population-based study

Author(s): Shireen Sindi, Laura Monica Pérez, Davide L. Vetrano, Federico Triolo, Ingemar Kåreholt, Linnea Sjöberg, Alexander Darin-Mattsson, Miia Kivipelto, Marco Inzitari, Amaia Calderón-Larrañaga
Published in: BMC Medicine, Issue 18, 2020, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-020-01846-w

Robust Multi-TE ASL-Based Blood–Brain Barrier Integrity Measurements

Author(s): Amnah Mahroo, Mareike Alicja Buck, Jörn Huber, Nora-Josefin Breutigam, Henk J. M. M. Mutsaerts, Martin Craig, Michael Chappell, Matthias Günther
Published in: Frontiers in Neuroscience, Issue 15, 2021, ISSN 1662-453X
Publisher: Frontiers Media
DOI: 10.3389/fnins.2021.719676

The genetic regulation of protein expression in cerebrospinal fluid

Author(s): Oskar Hansson, Atul Kumar, Shorena Janelidze, Erik Stomrud, Philip S Insel, Kaj Blennow, Henrik Zetterberg, Eric Fauman, Åsa K Hedman, Michael W Nagle, Christopher D Whelan, Denis Baird, Anders Mälarstig, Niklas Mattsson‐Carlgren
Published in: EMBO Molecular Medicine, Issue 15, 2023, ISSN 1757-4676
Publisher: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202216359

Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer’s disease

Author(s): Frederic Brosseron, Anne Maass, Luca Kleineidam, Kishore Aravind Ravichandran, Pablo García González, Róisín M. McManus, Christina Ising, Francesco Santarelli, Carl-Christian Kolbe, Lisa M. Häsler, Steffen Wolfsgruber, Marta Marquié, Mercè Boada, Adelina Orellana, Itziar de Rojas, Sandra Röske, Oliver Peters, Nicoleta-Carmen Cosma, Arda Cetindag, Xiao Wang, Josef Priller, Eike J. Spruth, S
Published in: Neuron, Issue 110, 2023, Page(s) 1009-1022.e4, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2021.12.016

Brain injury markers in new-onset seizures in adults: A pilot study

Author(s): Hanna Eriksson, Rakesh Kumar Banote, David Larsson, Kaj Blennow, Henrik Zetterberg, Johan Zelano
Published in: Seizure, Issue 92, 2024, Page(s) 62-67, ISSN 1059-1311
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.seizure.2021.08.012

Aging, sex, metabolic and life experience factors: Contributions to neuro-inflammaging in Alzheimer’s disease research

Author(s): Pasindu Hansana Singhaarachchi, Peter Antal, Frédéric Calon, Carsten Culmsee, Jean-Christophe Delpech, Martin Feldotto, Jorine Geertsema, Emmy E. Hoeksema, Aniko Korosi, Sophie Layé, Jonathan McQualter, Susanne R. de Rooij, Christoph Rummel, Mary Slayo, Luba Sominsky, Sarah J. Spencer
Published in: Neuroscience & Biobehavioral Reviews, Issue 162, 2024, Page(s) 105724, ISSN 0149-7634
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2024.105724

Multidomain Interventions to Prevent Cognitive Impairment, Alzheimer's Disease, and Dementia: From FINGER to World-Wide FINGERS

Author(s): A. Rosenberg, F. Mangialasche, T. Ngandu, A. Solomon, Miia Kivipelto
Published in: The Journal of Prevention of Alzheimer's Disease, Issue 7, 2025, Page(s) 29-36, ISSN 2274-5807
Publisher: SPRINGER BASEL AG
DOI: 10.14283/jpad.2019.41

Growth differentiation factor 15 increases in both cerebrospinal fluid and serum during pregnancy

Author(s): Ulrika Andersson-Hall, Pernilla Svedin, Carina Mallard, Kaj Blennow, Henrik Zetterberg, Agneta Holmäng
Published in: PLOS ONE, Issue 16, 2023, Page(s) e0248980, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0248980

N-terminal and mid-region tau fragments as fluid biomarkers in neurological diseases

Author(s): Anniina Snellman, Juan Lantero-Rodriguez, Andreja Emeršič, Agathe Vrillon, Thomas K Karikari, Nicholas J Ashton, Milica Gregorič Kramberger, Saša Čučnik, Claire Paquet, Uroš Rot, Henrik Zetterberg, Kaj Blennow
Published in: Brain, Issue 145, 2022, Page(s) 2834-2848, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awab481

A genome-wide search for determinants of survival in 1926 patients with advanced colorectal cancer with follow-up in over 22,000 patients

Author(s): Christopher Wills, Yazhou He, Matthew G. Summers, Yi Lin, Amanda I. Phipps, Katie Watts, Philip J. Law, Nada A. Al-Tassan, Timothy S. Maughan, Richard Kaplan, Richard S. Houlston, Ulrike Peters, Polly A. Newcomb, Andrew T. Chan, Daniel D. Buchanan, Steve Gallinger, Loic L. Marchand, Rish K. Pai, Qian Shi, Steven R. Alberts, Victoria Gray, Hannah D. West, Valentina Escott-Price, Malcolm G. Dunlop,
Published in: European Journal of Cancer, Issue 159, 2023, Page(s) 247-258, ISSN 0959-8049
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.ejca.2021.09.047

Proinflammatory protein signatures in cryptogenic and large artery atherosclerosis stroke

Author(s): Lukas Holmegaard, Tara M. Stanne, Ulf Andreasson, Henrik Zetterberg, Kaj Blennow, Christian Blomstrand, Katarina Jood, Christina Jern
Published in: Acta Neurologica Scandinavica, Issue 143, 2023, Page(s) 303-312, ISSN 0001-6314
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ane.13366

The Neuroimmune Response to Surgery – An Exploratory Study of Trauma-Induced Changes in Innate Immunity and Heart Rate Variability

Author(s): Malin Hildenborg, Jessica Kåhlin, Fredrik Granath, Anna Schening, Anna Granström, Anette Ebberyd, Lena Klevenvall, Henrik Zetterberg, Jinming Han, Todd T. Schlegel, Robert Harris, Helena Erlandsson Harris, Lars I. Eriksson
Published in: Frontiers in Immunology, Issue 13, 2022, ISSN 1664-3224
Publisher: FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2022.911744

Circulating metabolites modulated by diet are associated with depression

Author(s): Ashley van der Spek, Isobel D. Stewart, Brigitte Kühnel, Maik Pietzner, Tahani Alshehri, Friederike Gauß, Pirro G. Hysi, Siamak MahmoudianDehkordi, Almut Heinken, Annemarie I. Luik, Karl-Heinz Ladwig, Gabi Kastenmüller, Cristina Menni, Johannes Hertel, M. Arfan Ikram, Renée de Mutsert, Karsten Suhre, Christian Gieger, Konstantin Strauch, Henry Völzke, Thomas Meitinger, Massimo Mangino, Antoni
Published in: Molecular Psychiatry, Issue 28, 2023, Page(s) 3874-3887, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-023-02180-2

Seed amplification and neurodegeneration marker trajectories in individuals at risk of prion disease

Author(s): Tze How Mok, Akin Nihat, Nour Majbour, Danielle Sequeira, Leah Holm-Mercer, Thomas Coysh, Lee Darwent, Mark Batchelor, Bradley R Groveman, Christina D Orr, Andrew G Hughson, Amanda Heslegrave, Rhiannon Laban, Elena Veleva, Ross W Paterson, Ashvini Keshavan, Jonathan M Schott, Imogen J Swift, Carolin Heller, Jonathan D Rohrer, Alexander Gerhard, Christopher Butler, James B Rowe, Mario Masellis, Mil
Published in: Brain, Issue 146, 2023, Page(s) 2570-2583, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awad101

Hypotension during transsphenoidal pituitary surgery associated with increase in plasma levels of brain injury markers

Author(s): Martin Thorsson, Tobias Hallén, Daniel S. Olsson, Kaj Blennow, Henrik Zetterberg, Gudmundur Johannsson, Thomas Skoglund, Jonatan Oras
Published in: Acta Anaesthesiologica Scandinavica, Issue 67, 2023, Page(s) 1363-1372, ISSN 0001-5172
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/aas.14315

Neurofilament light chain on intensive care admission is an independent predictor of mortality in COVID-19: a prospective multicenter study

Author(s): Theodor Sievert, Ingrid Didriksson, Martin Spångfors, Gisela Lilja, Kaj Blennow, Henrik Zetterberg, Attila Frigyesi, Hans Friberg
Published in: Intensive Care Medicine Experimental, Issue 11, 2023, ISSN 2197-425X
Publisher: SPRINGER
DOI: 10.1186/s40635-023-00547-x

Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer’s disease, restores synapse integrity and memory in a disease mouse model

Author(s): Nuria Martin Flores, Marina Podpolny, Faye McLeod, Isaac Workman, Karen Crawford, Dobril Ivanov, Ganna Leonenko, Valentina Escott-Price, Patricia C Salinas
Published in: eLife, Issue 12, 2024, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.89453.3

[11C]metoclopramide is a sensitive radiotracer to measure moderate decreases in P-glycoprotein function at the blood-brain barrier

Author(s): Severin Mairinger, Sarah Leterrier, Thomas Filip, Mathilde Löbsch, Jens Pahnke, Irene Hernández-Lozano, Johann Stanek, Nicolas Tournier, Markus Zeitlinger, Marcus Hacker, Oliver Langer, Thomas Wanek
Published in: Journal of Cerebral Blood Flow & Metabolism, Issue 44, 2025, Page(s) 142-152, ISSN 0271-678X
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1177/0271678x231202336

Screening for neurodegeneration in Langerhans cell histiocytosis with neurofilament light in plasma

Author(s): Malin Sveijer, Tatiana von Bahr Greenwood, Martin Jädersten, Egle Kvedaraite, Henrik Zetterberg, Kaj Blennow, Magda Lourda, Désirée Gavhed, Jan‐Inge Henter
Published in: British Journal of Haematology, Issue 198, 2023, Page(s) 721-728, ISSN 0007-1048
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjh.18247

Tackling clinical heterogeneity across the amyotrophic lateral sclerosis–frontotemporal dementia spectrum using a transdiagnostic approach

Author(s): Rebekah M Ahmed, Martina Bocchetta, Emily G Todd, Nga Yan Tse, Emma M Devenney, Sicong Tu, Jashelle Caga, John R Hodges, Glenda M Halliday, Muireann Irish, Matthew C Kiernan, Olivier Piguet, Jonathan D Rohrer
Published in: Brain Communications, Issue 3, 2021, ISSN 2632-1297
Publisher: OXFORD UNIVERSITY PRESS
DOI: 10.1093/braincomms/fcab257

Test‐retest variability of plasma biomarkers in Alzheimer's disease and its effects on clinical prediction models

Author(s): Nicholas C. Cullen, Shorena Janelidze, Niklas Mattsson‐Carlgren, Sebastian Palmqvist, Tobias Bittner, Ivonne Suridjan, Alexander Jethwa, Gwendlyn Kollmorgen, Wagner S. Brum, Henrik Zetterberg, Kaj Blennow, Erik Stomrud, Oskar Hansson
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 797-806, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12706

Prodromal language impairment in genetic frontotemporal dementia within the GENFI cohort

Author(s): Kiran Samra, Amy M. MacDougall, Arabella Bouzigues, Martina Bocchetta, David M. Cash, Caroline V. Greaves, Rhian S. Convery, John C. van Swieten, Lize Jiskoot, Harro Seelaar, Fermin Moreno, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B. Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe, Alexandre
Published in: Journal of the Neurological Sciences, Issue 451, 2024, Page(s) 120711, ISSN 0022-510X
Publisher: Elsevier BV
DOI: 10.1016/j.jns.2023.120711

Astrocyte-derived neurons provide excitatory input to the adult striatal circuitry

Author(s): Matthijs C. Dorst, María Díaz-Moreno, David O. Dias, Eduardo L. Guimarães, Daniel Holl, Jannis Kalkitsas, Gilad Silberberg, Christian Göritz
Published in: Proceedings of the National Academy of Sciences, Issue 118, 2022, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2104119118

Neurofilaments can differentiate ALS subgroups and ALS from common diagnostic mimics

Author(s): Arvin Behzadi, Fani Pujol-Calderón, Anton E. Tjust, Anna Wuolikainen, Kina Höglund, Karin Forsberg, Erik Portelius, Kaj Blennow, Henrik Zetterberg, Peter Munch Andersen
Published in: Scientific Reports, Issue 11, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-01499-6

Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies

Author(s): Yuriy Pomeshchik, Oxana Klementieva, Jeovanis Gil, Isak Martinsson, Marita Grønning Hansen, Tessa de Vries, Anna Sancho-Balsells, Kaspar Russ, Ekaterina Savchenko, Anna Collin, Ana Rita Vaz, Silvia Bagnoli, Benedetta Nacmias, Claire Rampon, Sandro Sorbi, Dora Brites, György Marko-Varga, Zaal Kokaia, Melinda Rezeli, Gunnar K. Gouras, Laurent Roybon
Published in: Stem Cell Reports, Issue 15, 2022, Page(s) 256-273, ISSN 2213-6711
Publisher: Cell Press
DOI: 10.1016/j.stemcr.2020.06.001

Correlative Chemical Imaging and Spatial Chemometrics Delineate Alzheimer Plaque Heterogeneity at High Spatial Resolution

Author(s): Patrick M. Wehrli, Junyue Ge, Wojciech Michno, Srinivas Koutarapu, Ambra Dreos, Durga Jha, Henrik Zetterberg, Kaj Blennow, Jörg Hanrieder
Published in: JACS Au, Issue 3, 2023, Page(s) 762-774, ISSN 2691-3704
Publisher: AMER CHEMICAL SOC
DOI: 10.1021/jacsau.2c00492

Blood biomarkers for neuroaxonal injury and astrocytic activation in chemotherapy-induced peripheral neuropathy

Author(s): Jamila Adra, Daniel Giglio, Per Karlsson, Henrik Zetterberg, Zakaria Einbeigi
Published in: Acta Oncologica, Issue 63, 2024, Page(s) 636-641, ISSN 0284-186X
Publisher: Taylor & Francis
DOI: 10.2340/1651-226x.2024.39895

Melatonin: A potential nighttime guardian against Alzheimer’s

Author(s): Zefan Zhang, Pei Xue, Barbara B. Bendlin, Henrik Zetterberg, Fernanda De Felice, Xiao Tan, Christian Benedict
Published in: Molecular Psychiatry, Issue 30, 2024, Page(s) 237-250, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-024-02691-6

<scp>α‐Synuclein</scp> induces deficiency in clathrin‐mediated endocytosis through inhibiting synaptojanin1 expression

Author(s): Dong‐Yan Song, Lin Yuan, Na Cui, Cong Feng, Lanxia Meng, Xin‐He Wang, Man Xiang, Di Liu, Chun Wang, Zhentao Zhang, Jia‐Yi Li, Wen Li
Published in: Journal of Neurochemistry, Issue 167, 2023, Page(s) 461-484, ISSN 0022-3042
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/jnc.15974

A prospective feasibility trial exploring novel biomarkers for neurotoxicity after isolated limb perfusion

Author(s): Anna Corderfeldt Keiller, Markus Axelsson, Gudrun Bragadottir, Kaj Blennow, Henrik Zetterberg, Roger Olofsson Bagge
Published in: Perfusion, Issue 39, 2025, Page(s) 1657-1666, ISSN 0267-6591
Publisher: SAGE Publications
DOI: 10.1177/02676591231213506

Author(s): Dániel Veréb, Mite Mijalkov, Anna Canal-Garcia, Yu-Wei Chang, Emiliano Gomez-Ruiz, Blanca Zufiria Gerboles, Miia Kivipelto, Per Svenningsson, Henrik Zetterberg, Giovanni Volpe, Matthew Betts, Heidi IL Jacobs, Joana B Pereira
Published in: eLife, Issue 12, 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.87188

Medication use and risk of amyotrophic lateral sclerosis—a systematic review

Author(s): Can Cui, Jiangwei Sun, Kyla A. McKay, Caroline Ingre, Fang Fang
Published in: BMC Medicine, Issue 20, 2023, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-022-02442-w

Tissue specific LRRK2 interactomes reveal a distinct striatal functional unit

Author(s): Yibo Zhao, Nikoleta Vavouraki, Ruth C. Lovering, Valentina Escott-Price, Kirsten Harvey, Patrick A. Lewis, Claudia Manzoni
Published in: PLOS Computational Biology, Issue 19, 2023, Page(s) e1010847, ISSN 1553-7358
Publisher: PLOS
DOI: 10.1371/journal.pcbi.1010847

Plasma biomarkers of Alzheimer’s disease improve prediction of cognitive decline in cognitively unimpaired elderly populations

Author(s): Nicholas C. Cullen, Antoine Leuzy, Shorena Janelidze, Sebastian Palmqvist, Anna L. Svenningsson, Erik Stomrud, Jeffrey L. Dage, Niklas Mattsson-Carlgren, Oskar Hansson
Published in: Nature Communications, Issue 12, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-23746-0

Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis

Author(s): Marianne Chapleau, Renaud La Joie, Keir Yong, Federica Agosta, Isabel Elaine Allen, Liana Apostolova, John Best, Baayla D C Boon, Sebastian Crutch, Massimo Filippi, Giorgio Giulio Fumagalli, Daniela Galimberti, Jonathan Graff-Radford, Lea T Grinberg, David J Irwin, Keith A Josephs, Mario F Mendez, Patricio Chrem Mendez, Raffaella Migliaccio, Zachary A Miller, Maxime Montembeault, Melissa E Murray,
Published in: The Lancet Neurology, Issue 23, 2024, Page(s) 168-177, ISSN 1474-4422
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1474-4422(23)00414-3

Structural basis of epitope recognition by anti-alpha-synuclein antibodies MJFR14-6-4-2

Author(s): Ilva Liekniņa, Lasse Reimer, Teodors Panteļejevs, Alons Lends, Kristaps Jaudzems, Aadil El-Turabi, Hjalte Gram, Anissa Hammi, Poul Henning Jensen, Kaspars Tārs
Published in: npj Parkinson's Disease, Issue 10, 2024, ISSN 2373-8057
Publisher: SPRINGER NATURE, GERMANY
DOI: 10.1038/s41531-024-00822-y

Extracellular fluid, cerebrospinal fluid and plasma biomarkers of axonal and neuronal injury following intracerebral hemorrhage

Author(s): Lovisa Tobieson, Henrik Zetterberg, Kaj Blennow, Niklas Marklund
Published in: Scientific Reports, Issue 11, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-96364-x

Cavity Lasing Characteristics of Thioflavin T and Thioflavin X in Different Solvents and Their Interaction with DNA for the Controlled Reduction of a Light Amplification Threshold in Solid-State Biofilms

Author(s): K. Rusakov, S. Demianiuk, E. Jalonicka, P. Hanczyc
Published in: ACS Applied Optical Materials, Issue 1, 2024, Page(s) 1922-1929, ISSN 2771-9855
Publisher: -
DOI: 10.1021/acsaom.3c00264

Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

Author(s): Yann Le Guen, Guo Luo, Aditya Ambati, Vincent Damotte, Iris Jansen, Eric Yu, Aude Nicolas, Itziar de Rojas, Thiago Peixoto Leal, Akinori Miyashita, Céline Bellenguez, Michelle Mulan Lian, Kayenat Parveen, Takashi Morizono, Hyeonseul Park, Benjamin Grenier-Boley, Tatsuhiko Naito, Fahri Küçükali, Seth D. Talyansky, Selina Maria Yogeshwar, Vicente Sempere, Wataru Satake, Victoria Alvarez, Beatric
Published in: Proceedings of the National Academy of Sciences, Issue 120, 2023, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2302720120

Quantification of the trans-synaptic partners neurexin-neuroligin in CSF of neurodegenerative diseases by parallel reaction monitoring mass spectrometry

Author(s): Elena Camporesi, Johanna Nilsson, Agathe Vrillon, Emmanuel Cognat, Claire Hourregue, Henrik Zetterberg, Kaj Blennow, Bruno Becker, Ann Brinkmalm, Claire Paquet, Gunnar Brinkmalm
Published in: eBioMedicine, Issue 75, 2022, Page(s) 103793, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2021.103793

Blood–Brain Barrier Disruption and Its Involvement in Neurodevelopmental and Neurodegenerative Disorders

Author(s): Ana Aragón-González, Pamela J. Shaw, Laura Ferraiuolo
Published in: International Journal of Molecular Sciences, Issue 23, 2025, Page(s) 15271, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232315271

Brevican and Neurocan Peptides as Potential Cerebrospinal Fluid Biomarkers for Differentiation Between Vascular Dementia and Alzheimer’s Disease

Author(s): Karolina Minta, Gunnar Brinkmalm, Erik Portelius, Per Johansson, Johan Svensson, Petronella Kettunen, Anders Wallin, Henrik Zetterberg, Kaj Blennow, Ulf Andreasson
Published in: Journal of Alzheimer's Disease, Issue 79, 2024, Page(s) 729-741, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-201039

Gray matter hypoperfusion is a late pathological event in the course of Alzheimer’s disease

Author(s): Khazar Ahmadi, Joana B Pereira, David Berron, Jacob Vogel, Silvia Ingala, Olof T Strandberg, Shorena Janelidze, Frederik Barkhof, Josef Pfeuffer, Linda Knutsson, Danielle van Westen, Sebastian Palmqvist, Henk JMM Mutsaerts, Oskar Hansson
Published in: Journal of Cerebral Blood Flow & Metabolism, Issue 43, 2025, Page(s) 565-580, ISSN 0271-678X
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1177/0271678x221141139

No neurochemical evidence of neuronal injury or glial activation in children with Paediatric Acute-onset Neuropsychiatric Syndrome. An explorative pilot study

Author(s): Mats Johnson, Elisabeth Fernell, Christopher Gillberg, Anders Fasth, Lisa Dinkler, Kaj Blennow, Henrik Zetterberg
Published in: The World Journal of Biological Psychiatry, Issue 22, 2022, Page(s) 800-804, ISSN 1562-2975
Publisher: WFSBP
DOI: 10.1080/15622975.2021.1907716

LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy

Author(s): Susanne Nichterwitz, Jik Nijssen, Helena Storvall, Christoph Schweingruber, Laura Helen Comley, Ilary Allodi, Mirjam van der Lee, Qiaolin Deng, Rickard Sandberg, Eva Hedlund
Published in: Genome Research, Issue 30, 2021, Page(s) 1083-1096, ISSN 1088-9051
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gr.265017.120

Genome‐wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer

Author(s): Katie Watts, Christopher Wills, Ayman Madi, Claire Palles, Timothy S. Maughan, Richard Kaplan, Nada A. Al‐Tassan, Rachel Kerr, David Kerr, Victoria Gray, Hannah West, Richard S. Houlston, Valentina Escott‐Price, Jeremy P. Cheadle
Published in: International Journal of Cancer, Issue 149, 2023, Page(s) 1713-1722, ISSN 0020-7136
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ijc.33739

The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia: A GENFI study

Author(s): Lize C. Jiskoot, Lucy L. Russell, Georgia Peakman, Rhian S. Convery, Caroline V. Greaves, Martina Bocchetta, Jackie M. Poos, Harro Seelaar, Lucia A.A. Giannini, John C. van Swieten, Rick van Minkelen, Yolande A.L. Pijnenburg, James B. Rowe, Barbara Borroni, Daniela Galimberti, Mario Masellis, Carmela Tartaglia, Elizabeth Finger, Chris R. Butler, Caroline Graff, Robert Laforce, Raquel Sanchez-Valle
Published in: Journal of the Neurological Sciences, Issue 446, 2024, Page(s) 120590, ISSN 0022-510X
Publisher: Elsevier BV
DOI: 10.1016/j.jns.2023.120590

Blood β‐synuclein is related to amyloid PET positivity in memory clinic patients

Author(s): Patrick Oeckl, Marina Bluma, Marco Bucci, Steffen Halbgebauer, Konstantinos Chiotis, Anna Sandebring‐Matton, Nicholas J. Ashton, Guglielmo Di Molfetta, Lana Grötschel, Miia Kivipelto, Kaj Blennow, Henrik Zetterberg, Irina Savitcheva, Agneta Nordberg, Markus Otto
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 4896-4907, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13046

Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer’s disease

Author(s): Joana B Pereira, Shorena Janelidze, Ruben Smith, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Charlotte E Teunissen, Henrik Zetterberg, Erik Stomrud, Nicholas J Ashton, Kaj Blennow, Oskar Hansson
Published in: Brain, Issue 144, 2024, Page(s) 3505-3516, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awab223

Tilavonemab in early Alzheimer’s disease: results from a phase 2, randomized, double-blind study

Author(s): Hana Florian, Deli Wang, Steven E Arnold, Mercè Boada, Qi Guo, Ziyi Jin, Hui Zheng, Nahome Fisseha, Hari Varun Kalluri, Beatrice Rendenbach-Mueller, Kumar Budur, Michael Gold
Published in: Brain, Issue 146, 2023, Page(s) 2275-2284, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awad024

Single-cell and spatial transcriptomics enables probabilistic inference of cell type topography

Author(s): Alma Andersson, Joseph Bergenstråhle, Michaela Asp, Ludvig Bergenstråhle, Aleksandra Jurek, José Fernández Navarro, Joakim Lundeberg
Published in: Communications Biology, Issue 3, 2022, ISSN 2399-3642
Publisher: NATURE PORTFOLIO
DOI: 10.1038/s42003-020-01247-y

Plasma neurofilament light chain protein is not increased in forensic psychiatric populations: a pilot study

Author(s): Anja Fernqvist, Eirini Alexiou, Henrik Zetterberg, Katarina Howner, Thomas Nilsson, Peter Andiné
Published in: Frontiers in Psychiatry, Issue 14, 2023, ISSN 1664-0640
Publisher: Frontiers Research Foundation
DOI: 10.3389/fpsyt.2023.1176266

Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes

Author(s): Claudia Cicognola, Niklas Mattsson-Carlgren, Danielle van Westen, Henrik Zetterberg, Kaj Blennow, Sebastian Palmqvist, Khazar Ahmadi, Olof Strandberg, Erik Stomrud, Shorena Janelidze, Oskar Hansson
Published in: Neurology, Issue 101, 2024, ISSN 0028-3878
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000207358

Preanalytical stability of plasma/serum brain‐derived tau

Author(s): Fernando Gonzalez‐Ortiz, Alexandre Dias, Michael Turton, Rui Magalhães, Przemysław R. Kac, Manuel Correia, Peter Harrison, Henrik Zetterberg, Luís F. Maia, Kaj Blennow, Thomas K. Karikari
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 4764-4770, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13156

A co-culture model system to quantify antibody-dependent cellular cytotoxicity in human breast cancer cells using an engineered natural killer cell line

Author(s): Roos Vincken, Ana Ruiz-Saenz
Published in: STAR Protocols, Issue 4, 2024, Page(s) 102224, ISSN 2666-1667
Publisher: ELSEVIER, AMSTERDAM
DOI: 10.1016/j.xpro.2023.102224

Global Prevalence of Young-Onset Dementia

Author(s): Stevie Hendriks, Kirsten Peetoom, Christian Bakker, Wiesje M. van der Flier, Janne M. Papma, Raymond Koopmans, Frans R. J. Verhey, Marjolein de Vugt, Sebastian Köhler, null null, Adrienne Withall, Juliette L. Parlevliet, Özgül Uysal-Bozkir, Roger C. Gibson, Susanne M. Neita, Thomas Rune Nielsen, Lise C. Salem, Jenny Nyberg, Marcos Antonio Lopes, Jacqueline C. Dominguez, Ma Fe De Guzman, Alexand
Published in: JAMA Neurology, Issue 78, 2024, Page(s) 1080, ISSN 2168-6149
Publisher: American Medical Association
DOI: 10.1001/jamaneurol.2021.2161

Circumventing the packaging limit of AAV-mediated gene replacement therapy for neurological disorders

Author(s): Lara Marrone, Paolo M. Marchi, Mimoun Azzouz
Published in: Expert Opinion on Biological Therapy, Issue 22, 2023, Page(s) 1163-1176, ISSN 1471-2598
Publisher: Ashley Publications Ltd.
DOI: 10.1080/14712598.2022.2012148

Associations of Fully Automated CSF and Novel Plasma Biomarkers With Alzheimer Disease Neuropathology at Autopsy

Author(s): Michel J. Grothe, Alexis Moscoso, Nicholas J. Ashton, Thomas K. Karikari, Juan Lantero-Rodriguez, Anniina Snellman, Henrik Zetterberg, Kaj Blennow, Michael Schöll, null null
Published in: Neurology, Issue 97, 2024, ISSN 0028-3878
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000012513

CSF biomarkers of neurotoxicity in childhood cancer survivors after cranial radiotherapy or surgery

Author(s): Erik Fernström, Marianne Jarfelt, Malin Blomstrand, Birgitta Lannering, Markus Axelsson, Pontus Wasling, Thomas Björk‐Eriksson, Henrik Zetterberg, Marie Kalm
Published in: Annals of Clinical and Translational Neurology, Issue 11, 2024, Page(s) 2382-2391, ISSN 2328-9503
Publisher: WILEY
DOI: 10.1002/acn3.52152

Human brain clearance imaging: Pathways taken by magnetic resonance imaging contrast agents after administration in cerebrospinal fluid and blood

Author(s): Matthias J. P. van Osch, Anders Wåhlin, Paul Scheyhing, Ingrid Mossige, Lydiane Hirschler, Anders Eklund, Klara Mogensen, Ryszard Gomolka, Alexander Radbruch, Sara Qvarlander, Andreas Decker, Maiken Nedergaard, Yuki Mori, Per Kristian Eide, Katerina Deike, Geir Ringstad
Published in: NMR in Biomedicine, Issue 37, 2024, ISSN 0952-3480
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/nbm.5159

Editorial: Journey to the Center of the Brain: Cell Physiology and Intercellular Communication in White Matter

Author(s): Grace Flower, Nicola B. Hamilton, Maria Kukley
Published in: Frontiers in Cellular Neuroscience, Issue 16, 2022, ISSN 1662-5102
Publisher: Frontiers Research Foundation
DOI: 10.3389/fncel.2022.864368

Predicting sojourn times across dementia disease stages, institutionalization, and mortality

Author(s): Ashley E Tate, Vincent Bouteloup, Ingrid S. van Maurik, Delphine Jean, Arenda Mank, Andreja Speh, Valerie Boilet, Argonde van Harten, Maria Eriksdotter, Anders Wimo, Carole Dufouil, Wiesje M. van der Flier, Linus Jönsson
Published in: Alzheimer's & Dementia, Issue 20, 2024, Page(s) 809-818, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13488

The Gut Microbiota in Parkinson Disease: Interactions with Drugs and Potential for Therapeutic Applications

Author(s): Elisa Menozzi, Anthony H. V. Schapira
Published in: CNS Drugs, Issue 38, 2024, Page(s) 315-331, ISSN 1172-7047
Publisher: Adis International Ltd.
DOI: 10.1007/s40263-024-01073-4

Thalamic and Cerebellar Regional Involvement across the ALS–FTD Spectrum and the Effect of C9orf72

Author(s): Martina Bocchetta, Emily G. Todd, Nga Yan Tse, Emma M. Devenney, Sicong Tu, Jashelle Caga, John R. Hodges, Glenda M. Halliday, Muireann Irish, Olivier Piguet, Matthew C. Kiernan, Jonathan D. Rohrer, Rebekah M. Ahmed
Published in: Brain Sciences, Issue 12, 2025, Page(s) 336, ISSN 2076-3425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/brainsci12030336

Biomarkers and genotypes in patients with Central nervous system infection caused by enterovirus

Author(s): Karolina Alsén, Marianela Patzi Churqui, Helene Norder, Karolina Rembeck, Henrik Zetterberg, Kaj Blennow, Fredrika Sahlgren, Anna Grahn
Published in: Infectious Diseases, Issue 56, 2024, Page(s) 722-731, ISSN 2374-4235
Publisher: TAYLOR & FRANCIS LTD
DOI: 10.1080/23744235.2024.2345712

Sex-Specific Microglial Responses to Glucocerebrosidase Inhibition: Relevance to GBA1-Linked Parkinson’s Disease

Author(s): Electra Brunialti, Alessandro Villa, Marco Toffoli, Sara Lucas Del Pozo, Nicoletta Rizzi, Clara Meda, Adriana Maggi, Anthony H. V. Schapira, Paolo Ciana
Published in: Cells, Issue 12, 2025, Page(s) 343, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells12030343

Optimized sample preparation and data analysis for TMT proteomic analysis of cerebrospinal fluid applied to the identification of Alzheimer’s disease biomarkers

Author(s): Sophia Weiner, Mathias Sauer, Pieter Jelle Visser, Betty M. Tijms, Egor Vorontsov, Kaj Blennow, Henrik Zetterberg, Johan Gobom
Published in: Clinical Proteomics, Issue 19, 2024, ISSN 1542-6416
Publisher: Humana Press, Inc.
DOI: 10.1186/s12014-022-09354-0

Cognitive Performance and Cerebrospinal Fluid Markers in Preclinical Alzheimer’s Disease: Results from the Gothenburg H70 Birth Cohort Studies

Author(s): Maya Arvidsson Rådestig, Johan Skoog, Henrik Zetterberg, Jürgen Kern, Anna Zettergren, Simona Sacuiu, Margda Waern, Hanna Wetterberg, Kaj Blennow, Ingmar Skoog, Silke Kern
Published in: Journal of Alzheimer's Disease, Issue 79, 2024, Page(s) 225-235, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-200751

Blood–Brain Barrier Permeability to Water Measured Using Multiple Echo Time Arterial Spin Labeling <scp>MRI</scp> in the Aging Human Brain

Author(s): Amnah Mahroo, Simon Konstandin, Matthias Günther
Published in: Journal of Magnetic Resonance Imaging, Issue 59, 2024, Page(s) 1269-1282, ISSN 1053-1807
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jmri.28874

Biometal Dyshomeostasis in Olfactory Mucosa of Alzheimer’s Disease Patients

Author(s): Riikka Lampinen, Veronika Górová, Simone Avesani, Jeffrey R. Liddell, Elina Penttilä, Táňa Závodná, Zdeněk Krejčík, Juha-Matti Lehtola, Toni Saari, Juho Kalapudas, Sanna Hannonen, Heikki Löppönen, Jan Topinka, Anne M. Koivisto, Anthony R. White, Rosalba Giugno, Katja M. Kanninen
Published in: International Journal of Molecular Sciences, Issue 23, 2024, Page(s) 4123, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23084123

The role of neurofilament light in genetic frontotemporal lobar degeneration

Author(s): Henrik Zetterberg, Charlotte Teunissen, John van Swieten, Jens Kuhle, Adam Boxer, Jonathan D Rohrer, Laura Mitic, Alexandra M Nicholson, Rodney Pearlman, Stella Mayo McCaughey, Nadine Tatton
Published in: Brain Communications, Issue 5, 2023, ISSN 2632-1297
Publisher: OXFORD UNIVERSITY PRESS
DOI: 10.1093/braincomms/fcac310

Italian, European, and international neuroinformatics efforts: An overview

Author(s): Alberto Redolfi, Damiano Archetti, Silvia De Francesco, Claudio Crema, Fabrizio Tagliavini, Raffaele Lodi, Roberta Ghidoni, Claudia A. M. Gandini Wheeler‐Kingshott, Daniel C. Alexander, Egidio D'Angelo
Published in: European Journal of Neuroscience, Issue 57, 2023, Page(s) 2017-2039, ISSN 0953-816X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ejn.15854

Postanoxic electrographic status epilepticus and serum biomarkers of brain injury

Author(s): Anna Lybeck, Hans Friberg, Niklas Nielsen, Malin Rundgren, Susann Ullén, Henrik Zetterberg, Kaj Blennow, Tobias Cronberg, Erik Westhall
Published in: Resuscitation, Issue 158, 2021, Page(s) 253-257, ISSN 0300-9572
Publisher: Elsevier BV
DOI: 10.1016/j.resuscitation.2020.10.027

The characterisation of subjective cognitive decline

Author(s): Frank Jessen, Rebecca E Amariglio, Rachel F Buckley, Wiesje M van der Flier, Ying Han, José Luis Molinuevo, Laura Rabin, Dorene M Rentz, Octavio Rodriguez-Gomez, Andrew J Saykin, Sietske A M Sikkes, Colette M Smart, Steffen Wolfsgruber, Michael Wagner
Published in: The Lancet Neurology, Issue 19, 2021, Page(s) 271-278, ISSN 1474-4422
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1474-4422(19)30368-0

CSF biomarkers for dementia

Author(s): Ashvini Keshavan, Frankie O’Shea, Miles D Chapman, Melanie S Hart, Michael PT Lunn, Ross W Paterson, Jonathan D Rohrer, Catherine J Mummery, Nick C Fox, Henrik Zetterberg, Jonathan M Schott
Published in: Practical Neurology, Issue 22, 2023, Page(s) 285-294, ISSN 1474-7758
Publisher: Blackwell Publishing Inc.
DOI: 10.1136/practneurol-2021-003310

Midlife improvements in financial situation are associated with a reduced dementia risk later in life: the CAIDE 30-year study

Author(s): S. Sindi, A. Darin-Mattsson, I. Kåreholt, J. Kulmala, T. Ngandu, T. Laatikainen, H. Soininen, M. Kivipelto
Published in: International Psychogeriatrics, Issue 32, 2025, Page(s) 1317-1324, ISSN 1041-6102
Publisher: Cambridge University Press
DOI: 10.1017/s104161021900173x

Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice

Author(s): Lalit Kaurani, Md Rezaul Islam, Urs Heilbronner, Dennis M Krüger, Jiayin Zhou, Aditi Methi, Judith Strauss, Ranjit Pradhan, Sophie Schröder, Susanne Burkhardt, Anna-Lena Schuetz, Tonatiuh Pena, Lena Erlebach, Anika Bühler, Monika Budde, Fanny Senner, Mojtaba Oraki Kohshour, Eva C Schulte, Max Schmauß, Eva Z Reininghaus, Georg Juckel, Deborah Kronenberg-Versteeg, Ivana Delalle, Francesca Odoard
Published in: The EMBO Journal, Issue 43, 2024, Page(s) 1420-1444, ISSN 1460-2075
Publisher: The EMBO Journal
DOI: 10.1038/s44318-024-00067-8

Costs of diagnosing early Alzheimer's disease in three European memory clinic settings: Results from the precision medicine in Alzheimer's disease project

Author(s): Anders Wimo, Bjørn‐Eivind Kirsebom, Santiago Timón‐Reina, Ellen Vromen, Per Selnes, Jaka Bon, Andreja Emersic, Milica Gregoric Kramberger, Andreja Speh, Pieter Jelle Visser, Bengt Winblad, Tormod Fladby
Published in: International Journal of Geriatric Psychiatry, Issue 39, 2024, ISSN 0885-6230
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/gps.6126

Association of CSF proteins with tau and amyloid β levels in asymptomatic 70-year-olds

Author(s): Julia Remnestål, Sofia Bergström, Jennie Olofsson, Evelina Sjöstedt, Mathias Uhlén, Kaj Blennow, Henrik Zetterberg, Anna Zettergren, Silke Kern, Ingmar Skoog, Peter Nilsson, Anna Månberg
Published in: Alzheimer's Research & Therapy, Issue 13, 2023, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-021-00789-5

Diagnostic accuracy of research criteria for prodromal frontotemporal dementia

Author(s): Alberto Benussi, Enrico Premi, Mario Grassi, Antonella Alberici, Valentina Cantoni, Stefano Gazzina, Silvana Archetti, Roberto Gasparotti, Giorgio G. Fumagalli, Arabella Bouzigues, Lucy L. Russell, Kiran Samra, David M. Cash, Martina Bocchetta, Emily G. Todd, Rhian S. Convery, Imogen Swift, Aitana Sogorb-Esteve, Carolin Heller, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Raquel Sanchez-Va
Published in: Alzheimer's Research & Therapy, Issue 16, 2024, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-024-01383-1

Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis

Author(s): Richeng Jiang, Una Smailovic, Hazal Haytural, Betty M. Tijms, Hao Li, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Johan Gobom, Susanne Frykman, Misaki Sekiguchi, Ryo Fujioka, Naoto Watamura, Hiroki Sasaguri, Sofie Nyström, Per Hammarström, Takaomi C. Saido, Vesna Jelic, Stina Syvänen, Henrik Zetterberg, Bengt Winblad, Jonas Bergquist, Pieter Jelle Visser, Per Nilsson
Published in: Acta Neuropathologica Communications, Issue 10, 2022, ISSN 2051-5960
Publisher: BioMed Central
DOI: 10.1186/s40478-022-01398-5

Biomarkers of brain injury after cardiac arrest; a statistical analysis plan from the TTM2 trial biobank investigators

Author(s): Marion Moseby-Knappe, Helena Levin, Kaj Blennow, Susann Ullén, Henrik Zetterberg, Gisela Lilja, Josef Dankiewicz, Janus Christian Jakobsen, Alice Lagebrant, Hans Friberg, Alistair Nichol, Kate Ainschough, Glenn M. Eastwood, Matt P. Wise, Matthew Thomas, Thomas Keeble, Alain Cariou, Christoph Leithner, Christian Rylander, Joachim Düring, Jan Bělohlávek, Anders Grejs, Ola Borgquist, Johan Undén
Published in: Resuscitation Plus, Issue 10, 2024, Page(s) 100258, ISSN 2666-5204
Publisher: ELSEVIER
DOI: 10.1016/j.resplu.2022.100258

CSF p-tau205: a biomarker of tau pathology in Alzheimer’s disease

Author(s): Juan Lantero-Rodriguez, Laia Montoliu-Gaya, Andrea L. Benedet, Agathe Vrillon, Julien Dumurgier, Emmanuel Cognat, Wagner S. Brum, Nesrine Rahmouni, Jenna Stevenson, Stijn Servaes, Joseph Therriault, Bruno Becker, Gunnar Brinkmalm, Anniina Snellman, Hanna Huber, Hlin Kvartsberg, Nicholas J. Ashton, Henrik Zetterberg, Claire Paquet, Pedro Rosa-Neto, Kaj Blennow
Published in: Acta Neuropathologica, Issue 147, 2024, ISSN 0001-6322
Publisher: Springer Verlag
DOI: 10.1007/s00401-023-02659-w

A Solve-RD ClinVar-based reanalysis of 1522 index cases from ERN-ITHACA reveals common pitfalls and misinterpretations in exome sequencing

Author(s): Anne-Sophie Denommé-Pichon, Leslie Matalonga, Elke de Boer, Adam Jackson, Elisa Benetti, Siddharth Banka, Ange-Line Bruel, Andrea Ciolfi, Jill Clayton-Smith, Bruno Dallapiccola, Yannis Duffourd, Kornelia Ellwanger, Chiara Fallerini, Christian Gilissen, Holm Graessner, Tobias B. Haack, Marketa Havlovicova, Alexander Hoischen, Nolwenn Jean-Marçais, Tjitske Kleefstra, Estrella López-Martín, Milan
Published in: Genetics in Medicine, Issue 25, 2024, Page(s) 100018, ISSN 1098-3600
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.gim.2023.100018

An accurate fully automated panel of plasma biomarkers for Alzheimer's disease

Author(s): Sebastian Palmqvist, Erik Stomrud, Nicholas Cullen, Shorena Janelidze, Ekaterina Manuilova, Alexander Jethwa, Tobias Bittner, Udo Eichenlaub, Ivonne Suridjan, Gwendlyn Kollmorgen, Matthias Riepe, Christine A.F. von Arnim, Hayrettin Tumani, Klaus Hager, Fedor Heidenreich, Niklas Mattsson‐Carlgren, Henrik Zetterberg, Kaj Blennow, Oskar Hansson
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 1204-1215, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12751

CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired individuals

Author(s): Joel Simrén, Wagner S. Brum, Nicholas J. Ashton, Andrea L. Benedet, Thomas K. Karikari, Hlin Kvartsberg, Emma Sjons, Firoza Z. Lussier, Mira Chamoun, Jenna Stevenson, Robert Hopewell, Vanessa Pallen, Keqiang Ye, Tharick A. Pascoal, Henrik Zetterberg, Pedro Rosa-Neto, Kaj Blennow
Published in: Alzheimer's Research & Therapy, Issue 14, 2023, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-022-01142-0

Effects of Meditation Training and Non-Native Language Training on Cognition in Older Adults

Author(s): Harriet Demnitz-King, Florence Requier, Tim Whitfield, Marco Schlosser, Julie Gonneaud, Caitlin Ware, Thorsten Barnhofer, Nina Coll-Padros, Sophie Dautricourt, Marion Delarue, Olga M. Klimecki, Léo Paly, Eric Salmon, Ann-Katrin Schild, Miranka Wirth, Eric Frison, Antoine Lutz, Gaël Chételat, Fabienne Collette, Natalie L. Marchant, null null, Florence Allais, Claire André, Eider Arenaza-Urquijo
Published in: JAMA Network Open, Issue 6, 2023, Page(s) e2317848, ISSN 2574-3805
Publisher: American medical association, Chicago
DOI: 10.1001/jamanetworkopen.2023.17848

Neuropsychiatric symptoms in genetic frontotemporal dementia: developing a new module for Clinical Rating Scales

Author(s): Kiran Samra, Amy Macdougall, Georgia Peakman, Arabella Bouzigues, Martina Bocchetta, David M Cash, Caroline V Greaves, Rhian S Convery, John C van Swieten, Lize C Jiskoot, Harro Seelaar, Fermin Moreno, Raquel Sánchez-Valle, Robert Laforce, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenbergh
Published in: Journal of Neurology, Neurosurgery & Psychiatry, Issue 94, 2023, Page(s) 357-368, ISSN 0022-3050
Publisher: BMJ Publishing Group
DOI: 10.1136/jnnp-2022-330152

Plasma neurofilament light protein correlates with diffusion tensor imaging metrics in frontotemporal dementia

Author(s): Nicola Spotorno, Olof Lindberg, Christer Nilsson, Maria Landqvist Waldö, Danielle van Westen, Karin Nilsson, Susanna Vestberg, Elisabet Englund, Henrik Zetterberg, Kaj Blennow, Jimmy Lätt, Nilsson Markus, Wahlund Lars-Olof, Santillo Alexander
Published in: PLOS ONE, Issue 15, 2020, Page(s) e0236384, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0236384

Effects of pre‐analytical procedures on blood biomarkers for Alzheimer's pathophysiology, glial activation, and neurodegeneration

Author(s): Nicholas J. Ashton, Marc Suárez‐Calvet, Thomas K. Karikari, Juan Lantero‐Rodriguez, Anniina Snellman, Mathias Sauer, Joel Simrén, Carolina Minguillon, Karine Fauria, Kaj Blennow, Henrik Zetterberg
Published in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Issue 13, 2023, ISSN 2352-8729
Publisher: WILEY
DOI: 10.1002/dad2.12168

Emissions from modern engines induce distinct effects in human olfactory mucosa cells, depending on fuel and aftertreatment

Author(s): Laura Mussalo, Simone Avesani, Muhammad Ali Shahbaz, Táňa Závodná, Liudmila Saveleva, Anssi Järvinen, Riikka Lampinen, Irina Belaya, Zdeněk Krejčík, Mariia Ivanova, Henri Hakkarainen, Juho Kalapudas, Elina Penttilä, Heikki Löppönen, Anne M. Koivisto, Tarja Malm, Jan Topinka, Rosalba Giugno, Päivi Aakko-Saksa, Sweelin Chew, Topi Rönkkö, Pasi Jalava, Katja M. Kanninen
Published in: Science of The Total Environment, Issue 905, 2024, Page(s) 167038, ISSN 0048-9697
Publisher: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.167038

Differential seeding and propagating efficiency of α-synuclein strains generated in different conditions

Author(s): Di Liu, Jian-Jun Guo, Ji-Hui Su, Alexander Svanbergsson, Lin Yuan, Caroline Haikal, Wen Li, Gunnar Gouras, Jia-Yi Li
Published in: Translational Neurodegeneration, Issue 10, 2023, ISSN 2047-9158
Publisher: BMC
DOI: 10.1186/s40035-021-00242-5

Targeting the GBA1 pathway to slow Parkinson disease: Insights into clinical aspects, pathogenic mechanisms and new therapeutic avenues

Author(s): Elisa Menozzi, Marco Toffoli, Anthony H.V. Schapira
Published in: Pharmacology & Therapeutics, Issue 246, 2024, Page(s) 108419, ISSN 0163-7258
Publisher: Pergamon Press
DOI: 10.1016/j.pharmthera.2023.108419

Subject-specific timing adaption in time-encoded arterial spin labeling imaging

Author(s): Nora-Josefin Breutigam, Daniel Christopher Hoinkiss, Simon Konstandin, Mareike Alicja Buck, Amnah Mahroo, Klaus Eickel, Federico von Samson-Himmelstjerna, Matthias Günther
Published in: Magnetic Resonance Materials in Physics, Biology and Medicine, Issue 37, 2024, Page(s) 53-68, ISSN 1352-8661
Publisher: -
DOI: 10.1007/s10334-023-01121-y

Assessing the commutability of candidate reference materials for the harmonization of neurofilament light measurements in blood

Author(s): Ulf Andreasson, Johan Gobom, Vincent Delatour, Guy Auclair, Yoav Noam, Stephen Lee, Jason Wen, Andreas Jeromin, Burak Arslan, Aleksandra Maceski, Eline Willemse, Henrik Zetterberg, Jens Kuhle, Kaj Blennow
Published in: Clinical Chemistry and Laboratory Medicine (CCLM), Issue 61, 2024, Page(s) 1245-1254, ISSN 1434-6621
Publisher: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/cclm-2022-1181

Longitudinal cerebral perfusion in presymptomatic genetic frontotemporal dementia: GENFI results

Author(s): Maurice Pasternak, Saira S. Mirza, Nicholas Luciw, Henri J. M. M. Mutsaerts, Jan Petr, David Thomas, David Cash, Martina Bocchetta, Maria Carmela Tartaglia, Sara B. Mitchell, Sandra E. Black, Morris Freedman, David Tang‐Wai, Ekaterina Rogaeva, Lucy L. Russell, Arabella Bouzigues, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Robert Laforce, Pietro Tiraboschi, Barbara Borroni, Daniela Gali
Published in: Alzheimer's & Dementia, Issue 20, 2024, Page(s) 3525-3542, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13750

Transcriptomics and weighted protein network analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson’s Disease

Author(s): Yibo Zhao, Matthew Bracher-Smith, Yuelin Li, Kirsten Harvey, Valentina Escott-Price, Patrick A. Lewis, Claudia Manzoni
Published in: npj Parkinson's Disease, Issue 10, 2024, ISSN 2373-8057
Publisher: Springer Nature
DOI: 10.1038/s41531-024-00761-8

High levels of kappa free light chain synthesis predict cognitive decline in relapsing-remitting multiple sclerosis

Author(s): Igal Rosenstein, Markus Axelsson, Lenka Novakova, Sofia Rasch, Kaj Blennow, Henrik Zetterberg, Jan Lycke
Published in: Frontiers in Immunology, Issue 14, 2023, ISSN 1664-3224
Publisher: FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2023.1106028

Spatial neurolipidomics—MALDI mass spectrometry imaging of lipids in brain pathologies

Author(s): Durga Jha, Kaj Blennow, Henrik Zetterberg, Jeffrey N. Savas, Jörg Hanrieder
Published in: Journal of Mass Spectrometry, Issue 59, 2024, ISSN 1076-5174
Publisher: IM Publications
DOI: 10.1002/jms.5008

Altered levels of CSF proteins in patients with FTD, presymptomatic mutation carriers and non-carriers

Author(s): Julia Remnestål, Linn Öijerstedt, Abbe Ullgren, Jennie Olofsson, Sofia Bergström, Kim Kultima, Martin Ingelsson, Lena Kilander, Mathias Uhlén, Anna Månberg, Caroline Graff, Peter Nilsson
Published in: Translational Neurodegeneration, Issue 9, 2022, ISSN 2047-9158
Publisher: BMC
DOI: 10.1186/s40035-020-00198-y

Cerebrospinal fluid proteomics in patients with Alzheimer’s disease reveals five molecular subtypes with distinct genetic risk profiles

Author(s): Betty M. Tijms, Ellen M. Vromen, Olav Mjaavatten, Henne Holstege, Lianne M. Reus, Sven van der Lee, Kirsten E. J. Wesenhagen, Luigi Lorenzini, Lisa Vermunt, Vikram Venkatraghavan, Niccoló Tesi, Jori Tomassen, Anouk den Braber, Julie Goossens, Eugeen Vanmechelen, Frederik Barkhof, Yolande A. L. Pijnenburg, Wiesje M. van der Flier, Charlotte E. Teunissen, Frode S. Berven, Pieter Jelle Visser
Published in: Nature Aging, Issue 4, 2024, Page(s) 33-47, ISSN 2662-8465
Publisher: Springer Nature
DOI: 10.1038/s43587-023-00550-7

Spatial RNA Sequencing Identifies Robust Markers of Vulnerable and Resistant Human Midbrain Dopamine Neurons and Their Expression in Parkinson’s Disease

Author(s): Julio Aguila, Shangli Cheng, Nigel Kee, Ming Cao, Menghan Wang, Qiaolin Deng, Eva Hedlund
Published in: Frontiers in Molecular Neuroscience, Issue 14, 2023, ISSN 1662-5099
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnmol.2021.699562

Towards cascading genetic risk in Alzheimer’s disease

Author(s): Andre Altmann, Leon M Aksman, Neil P Oxtoby, Alexandra L Young, null null, Michael Weiner, Paul Aisen, Ronald Petersen, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R Jack, William Jagust, Susan Landau, Monica Rivera-Mindt, Ozioma Okonkwo, Leslie M Shaw, Edward B Lee, Arthur W Toga, Laurel Beckett, Danielle Harvey, Robert C Green, Andrew J Saykin, Kwangsik Nho, Richard J Perrin, Duygu Tos
Published in: Brain, Issue 147, 2024, Page(s) 2680-2690, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awae176

Nutrition guidance within a multimodal intervention improves diet quality in prodromal Alzheimer’s disease: Multimodal Preventive Trial for Alzheimer’s Disease (MIND-ADmini)

Author(s): Nicholas Levak, Jenni Lehtisalo, Charlotta Thunborg, Eric Westman, Pia Andersen, Sandrine Andrieu, Laus M. Broersen, Nicola Coley, Tobias Hartmann, Gerd Faxén Irving, Francesca Mangialasche, Tiia Ngandu, Johannes Pantel, Anna Rosenberg, Shireen Sindi, Hilkka Soininen, Alina Solomon, Rui Wang, Miia Kivipelto
Published in: Alzheimer's Research & Therapy, Issue 16, 2024, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-024-01522-8

Alzheimer‐like biomarker heterogeneity in a preclinical elderly birth cohort: Insight46

Author(s): Mar Estarellas Garcia, Alexandra L. Young, Sarah E Keuss, Daniel C. Alexander, Jonathan M Schott
Published in: Alzheimer's & Dementia, Issue 18, 2023, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.067555

SOD1 mutations associated with amyotrophic lateral sclerosis analysis of variant severity

Author(s): Mariusz Berdyński, Przemysław Miszta, Krzysztof Safranow, Peter M. Andersen, Mitsuya Morita, Sławomir Filipek, Cezary Żekanowski, Magdalena Kuźma-Kozakiewicz
Published in: Scientific Reports, Issue 12, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-03891-8

Novel avenues of tau research

Author(s): Claire E. Sexton, Gal Bitan, Kathryn R. Bowles, Miroslaw Brys, Luc Buée, Mahmoud Bukar Maina, Claire D. Clelland, Ann D. Cohen, John F. Crary, Jeffrey L. Dage, Kristophe Diaz, Bess Frost, Li Gan, Alison M Goate, Lawrence I. Golbe, Oskar Hansson, Celeste M. Karch, Hartmuth C. Kolb, Renaud La Joie, Suzee E. Lee, Diana Matallana, Bruce L. Miller, Chiadi U. Onyike, Yakeel T. Quiroz, Jessica E. Rexach
Published in: Alzheimer's & Dementia, Issue 20, 2024, Page(s) 2240-2261, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13533

Differential early subcortical involvement in genetic FTD within the GENFI cohort

Author(s): Martina Bocchetta, Emily G. Todd, Georgia Peakman, David M. Cash, Rhian S. Convery, Lucy L. Russell, David L. Thomas, Juan Eugenio Iglesias, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B. Rowe, Rik Vandenberghe, Elizabet
Published in: NeuroImage: Clinical, Issue 30, 2024, Page(s) 102646, ISSN 2213-1582
Publisher: Elsevier BV
DOI: 10.1016/j.nicl.2021.102646

Ambroxol reverses tau and α-synuclein accumulation in a cholinergic N370S GBA1 mutation model

Author(s): Shi Yu Yang, Jan-Willem Taanman, Matthew Gegg, Anthony H V Schapira
Published in: Human Molecular Genetics, Issue 31, 2022, Page(s) 2396-2405, ISSN 0964-6906
Publisher: Oxford University Press
DOI: 10.1093/hmg/ddac038

Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology

Author(s): Nicholas J. Ashton, Wagner S. Brum, Guglielmo Di Molfetta, Andrea L. Benedet, Burak Arslan, Erin Jonaitis, Rebecca E. Langhough, Karly Cody, Rachael Wilson, Cynthia M. Carlsson, Eugeen Vanmechelen, Laia Montoliu-Gaya, Juan Lantero-Rodriguez, Nesrine Rahmouni, Cecile Tissot, Jenna Stevenson, Stijn Servaes, Joseph Therriault, Tharick Pascoal, Alberto Lleó, Daniel Alcolea, Juan Fortea, Pedro Rosa-Ne
Published in: JAMA Neurology, Issue 81, 2024, Page(s) 255, ISSN 2168-6149
Publisher: American Medical Association
DOI: 10.1001/jamaneurol.2023.5319

Tau pathology as determinant of changes in atrophy and cerebral blood flow: a multi-modal longitudinal imaging study

Author(s): Denise Visser, Sander C. J. Verfaillie, Iris Bosch, Iman Brouwer, Hayel Tuncel, Emma M. Coomans, Roos M. Rikken, Sophie E. Mastenbroek, Sandeep S. V. Golla, Frederik Barkhof, Elsmarieke van de Giessen, Bart N. M. van Berckel, Wiesje M. van der Flier, Rik Ossenkoppele
Published in: European Journal of Nuclear Medicine and Molecular Imaging, Issue 50, 2023, Page(s) 2409-2419, ISSN 1619-7070
Publisher: Springer Verlag
DOI: 10.1007/s00259-023-06196-2

Fine‐grained ordering of white matter degeneration in the Alzheimer’s disease pathophysiological cascade

Author(s): Christopher S Parker
Published in: Alzheimer's & Dementia, Issue 19, 2023, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.061865

Association of modifiable risk factors with progression to dementia in relation to amyloid and tau pathology

Author(s): Zsolt Huszár, Alina Solomon, Marie Anne Engh, Vanda Koszovácz, Tamás Terebessy, Zsolt Molnár, Péter Hegyi, András Horváth, Francesca Mangialasche, Miia Kivipelto, Gábor Csukly
Published in: Alzheimer's Research & Therapy, Issue 16, 2024, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-024-01602-9

Shared CSF Biomarker Profile in Idiopathic Normal Pressure Hydrocephalus and Subcortical Small Vessel Disease

Author(s): Anna Jeppsson, Maria Bjerke, Per Hellström, Kaj Blennow, Henrik Zetterberg, Petronella Kettunen, Carsten Wikkelsø, Anders Wallin, Mats Tullberg
Published in: Frontiers in Neurology, Issue 13, 2022, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2022.839307

Neurofilament light chain as neuronal injury marker – what is needed to facilitate implementation in clinical laboratory practice?

Author(s): Burak Arslan, Henrik Zetterberg
Published in: Clinical Chemistry and Laboratory Medicine (CCLM), Issue 61, 2024, Page(s) 1140-1149, ISSN 1434-6621
Publisher: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/cclm-2023-0036

Polygenic risk scores for Alzheimer's disease in relation to cognitive change: A representative sample from the general population followed over 16 years.

Author(s): Jenna Najar, Valgeir Thorvaldsson, Silke Kern, Johan Skoog, Margda Waern, Henrik Zetterberg, Kaj Blennow, Ingmar Skoog, Anna Zettergren
Published in: Neurobiology of Disease, Issue 189, 2023, Page(s) 106357, ISSN 0969-9961
Publisher: Academic Press
DOI: 10.1016/j.nbd.2023.106357

FRET-Based Screening Identifies p38 MAPK and PKC Inhibition as Targets for Prevention of Seeded α-Synuclein Aggregation

Author(s): Alexander Svanbergsson, Fredrik Ek, Isak Martinsson, Jordi Rodo, Di Liu, Edoardo Brandi, Caroline Haikal, Laura Torres-Garcia, Wen Li, Gunnar Gouras, Roger Olsson, Tomas Björklund, Jia-Yi Li
Published in: Neurotherapeutics, Issue 18, 2024, Page(s) 1692-1709, ISSN 1878-7479
Publisher: SPRINGER
DOI: 10.1007/s13311-021-01070-1

Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis

Author(s): Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg, Florian Deisenhammer
Published in: Multiple Sclerosis Journal, Issue 29, 2025, Page(s) 169-181, ISSN 1352-4585
Publisher: SAGE Publications
DOI: 10.1177/13524585221134213

The Uppsala APP deletion causes early onset autosomal dominant Alzheimer’s disease by altering APP processing and increasing amyloid β fibril formation

Author(s): María Pagnon de la Vega, Vilmantas Giedraitis, Wojciech Michno, Lena Kilander, Gökhan Güner, Mara Zielinski, Malin Löwenmark, RoseMarie Brundin, Torsten Danfors, Linda Söderberg, Irina Alafuzoff, Lars N.G. Nilsson, Anna Erlandsson, Dieter Willbold, Stephan A. Müller, Gunnar F. Schröder, Jörg Hanrieder, Stefan F. Lichtenthaler, Lars Lannfelt, Dag Sehlin, Martin Ingelsson
Published in: Science Translational Medicine, Issue 13, 2024, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abc6184

Correlation between cognitive assessment scores and circulating cerebral biomarkers in women with pre-eclampsia and eclampsia

Author(s): Emma Bokström-Rees, Henrik Zetterberg, Kaj Blennow, Roxanne Hastie, Sonja Schell, Catherine Cluver, Lina Bergman
Published in: Pregnancy Hypertension, Issue 31, 2024, Page(s) 38-45, ISSN 2210-7789
Publisher: Elsevier BV
DOI: 10.1016/j.preghy.2022.12.001

Data-driven modelling of neurodegenerative disease progression: thinking outside the black box

Author(s): Alexandra L. Young, Neil P. Oxtoby, Sara Garbarino, Nick C. Fox, Frederik Barkhof, Jonathan M. Schott, Daniel C. Alexander
Published in: Nature Reviews Neuroscience, Issue 25, 2024, Page(s) 111-130, ISSN 1471-003X
Publisher: Nature Publishing Group
DOI: 10.1038/s41583-023-00779-6

Cerebrospinal fluid biomarker panel for synaptic dysfunction in Alzheimer's disease

Author(s): Johanna Nilsson, Johan Gobom, Simon Sjödin, Gunnar Brinkmalm, Nicholas J. Ashton, Johan Svensson, Per Johansson, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm
Published in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Issue 13, 2023, ISSN 2352-8729
Publisher: WILEY
DOI: 10.1002/dad2.12179

A data-driven disease progression model of fluid biomarkers in genetic frontotemporal dementia

Author(s): Emma L van der Ende, Esther E Bron, Jackie M Poos, Lize C Jiskoot, Jessica L Panman, Janne M Papma, Lieke H Meeter, Elise G P Dopper, Carlo Wilke, Matthis Synofzik, Carolin Heller, Imogen J Swift, Aitana Sogorb-Esteve, Arabella Bouzigues, Barbara Borroni, Raquel Sanchez-Valle, Fermin Moreno, Caroline Graff, Robert Laforce, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Fing
Published in: Brain, Issue 145, 2022, Page(s) 1805-1817, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awab382

Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia

Author(s): Alberto Benussi, Antonella Alberici, Kiran Samra, Lucy L. Russell, Caroline V. Greaves, Martina Bocchetta, Simon Ducharme, Elizabeth Finger, Giorgio Fumagalli, Daniela Galimberti, Lize C. Jiskoot, Isabelle Le Ber, Mario Masellis, Benedetta Nacmias, James B. Rowe, Raquel Sanchez‐Valle, Harro Seelaar, Matthis Synofzik, null null, Jonathan D. Rohrer, Barbara Borroni
Published in: Alzheimer's & Dementia, Issue 18, 2023, Page(s) 1408-1423, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12485

Transcriptomic and epigenomic profiling reveals altered responses to diesel emissions in Alzheimer's disease both in vitro and in population‐based data

Author(s): Liudmila Saveleva, Tereza Cervena, Claudia Mengoni, Michal Sima, Zdenek Krejcik, Kristyna Vrbova, Jitka Sikorova, Laura Mussalo, Tosca O. E. de Crom, Zuzana Šímová, Mariia Ivanova, Muhammad Ali Shahbaz, Elina Penttilä, Heikki Löppönen, Anne M. Koivisto, M. Arfan Ikram, Pasi I Jalava, Tarja Malm, Sweelin Chew, Michal Vojtisek‐Lom, Jan Topinka, Rosalba Giugno, Pavel Rössner, Katja M. Kannin
Published in: Alzheimer's & Dementia, Issue 20, 2024, Page(s) 8825-8843, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.14347

Progression of Behavioral Disturbances and Neuropsychiatric Symptoms in Patients With Genetic Frontotemporal Dementia

Author(s): Alberto Benussi, Enrico Premi, Stefano Gazzina, Chiara Brattini, Elisa Bonomi, Antonella Alberici, Lize Jiskoot, John C. van Swieten, Raquel Sanchez-Valle, Fermin Moreno, Robert Laforce, Caroline Graff, Matthis Synofzik, Daniela Galimberti, Mario Masellis, Carmela Tartaglia, James B. Rowe, Elizabeth Finger, Rik Vandenberghe, Alexandre de Mendonça, Fabrizio Tagliavini, Isabel Santana, Simon Duchar
Published in: JAMA Network Open, Issue 4, 2021, Page(s) e2030194, ISSN 2574-3805
Publisher: AMERICAN MEDICAL ASSOCIATION CHICAGO
DOI: 10.1001/jamanetworkopen.2020.30194

The global Alzheimer's Association round robin study on plasma amyloid β methods

Author(s): Josef Pannee, Leslie M. Shaw, Magdalena Korecka, Teresa Waligorska, Charlotte E. Teunissen, Erik Stoops, Hugo M. J. Vanderstichele, Kimberley Mauroo, Inge M. W. Verberk, Ashvini Keshavan, Pedro Pesini, Leticia Sarasa, Maria Pascual‐Lucas, Noelia Fandos, José‐Antonio Allué, Erik Portelius, Ulf Andreasson, Ritsuko Yoda, Akinori Nakamura, Naoki Kaneko, Shieh‐Yueh Yang, Huei‐Chun Liu, Stefan
Published in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Issue 13, 2023, ISSN 2352-8729
Publisher: WILEY
DOI: 10.1002/dad2.12242

Exploring the Genotype–Phenotype Correlation in GBA-Parkinson Disease: Clinical Aspects, Biomarkers, and Potential Modifiers

Author(s): Elisa Menozzi, Anthony H. V. Schapira
Published in: Frontiers in Neurology, Issue 12, 2021, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2021.694764

A data-driven model of brain volume changes in progressive supranuclear palsy

Author(s): W. J. Scotton, M. Bocchetta, E. Todd, D. M. Cash, N. Oxtoby, L. VandeVrede, H. Heuer, null null, D. C. Alexander, J. B. Rowe, H. R. Morris, A. Boxer, J. D. Rohrer, P. A. Wijeratne
Published in: Brain Communications, Issue 4, 2022, ISSN 2632-1297
Publisher: BRAIN COMMUNICATIONS
DOI: 10.1093/braincomms/fcac098

Telomere Length Change in a Multidomain Lifestyle Intervention to Prevent Cognitive Decline: A Randomized Clinical Trial

Author(s): Shireen Sindi, Alina Solomon, Ingemar Kåreholt, Iiris Hovatta, Riitta Antikainen, Tuomo Hänninen, Esko Levälahti, Tiina Laatikainen, Jenni Lehtisalo, Jaana Lindström, Teemu Paajanen, Markku Peltonen, Dharma Singh Khalsa, Benjamin Wolozin, Timo Strandberg, Jaakko Tuomilehto, Hilkka Soininen, Tiia Ngandu, Miia Kivipelto, null null
Published in: The Journals of Gerontology: Series A, Issue 76, 2021, Page(s) 491-498, ISSN 1079-5006
Publisher: Gerontological Society of America
DOI: 10.1093/gerona/glaa279

Therapeutic music interventions with people with dementia living in residential aged care: Perspectives of residents, family members and care home staff from a cluster randomised controlled trial

Author(s): Young‐Eun C. Lee, Phoebe A. Stretton‐Smith, Jeanette Tamplin, Tanara Vieira Sousa, Felicity A. Baker
Published in: International Journal of Older People Nursing, Issue 17, 2023, ISSN 1748-3743
Publisher: Blackwell Publishing
DOI: 10.1111/opn.12445

Optimal combinations of CSF biomarkers for predicting cognitive decline and clinical conversion in cognitively unimpaired participants and mild cognitive impairment patients: A multi‐cohort study

Author(s): Gemma Salvadó, Victoria Larsson, Karly A Cody, Nicholas C Cullen, Erin M Jonaitis, Erik Stomrud, Gwendlyn Kollmorgen, Norbert Wild, Sebastian Palmqvist, Shorena Janelidze, Niklas Mattsson‐Carlgren, Henrik Zetterberg, Kaj Blennow, Sterling C Johnson, Rik Ossenkoppele, Oskar Hansson
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 2943-2955, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12907

Blood biomarkers for Alzheimer's disease and related disorders

Author(s): Henrik Zetterberg, Jonathan M. Schott
Published in: Acta Neurologica Scandinavica, Issue 146, 2022, Page(s) 51-55, ISSN 0001-6314
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ane.13628

P‐tau235: a novel biomarker for staging preclinical Alzheimer’s disease

Author(s): Juan Lantero‐Rodriguez, Anniina Snellman, Andrea L Benedet, Marta Milà‐Alomà, Elena Camporesi, Laia Montoliu‐Gaya, Nicholas J Ashton, Agathe Vrillon, Thomas K Karikari, Juan Domingo Gispert, Gemma Salvadó, Mahnaz Shekari, Christina E Toomey, Tammaryn L Lashley, Henrik Zetterberg, Marc Suárez‐Calvet, Gunnar Brinkmalm, Pedro Rosa Neto, Kaj Blennow
Published in: EMBO Molecular Medicine, Issue 13, 2023, ISSN 1757-4676
Publisher: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202115098

Time course of phosphorylated-tau181 in blood across the Alzheimer’s disease spectrum

Author(s): Alexis Moscoso, Michel J Grothe, Nicholas J Ashton, Thomas K Karikari, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Henrik Zetterberg, Kaj Blennow, Michael Schöll, null null
Published in: Brain, Issue 144, 2022, Page(s) 325-339, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awaa399

Association of APOE ɛ4 and Plasma p-tau181 with Preclinical Alzheimer’s Disease and Longitudinal Change in Hippocampus Function

Author(s): Alireza Salami, Rolf Adolfsson, Micael Andersson, Kaj Blennow, Anders Lundquist, Annelie Nordin Adolfsson, Michael Schöll, Henrik Zetterberg, Lars Nyberg
Published in: Journal of Alzheimer's Disease, Issue 85, 2024, Page(s) 1309-1320, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-210673

A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings

Author(s): Wagner S. Brum, Nicholas C. Cullen, Joseph Therriault, Shorena Janelidze, Nesrine Rahmouni, Jenna Stevenson, Stijn Servaes, Andrea L. Benedet, Eduardo R. Zimmer, Erik Stomrud, Sebastian Palmqvist, Henrik Zetterberg, Giovanni B. Frisoni, Nicholas J. Ashton, Kaj Blennow, Niklas Mattsson-Carlgren, Pedro Rosa-Neto, Oskar Hansson
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-46603-2

Plasma pTau181 and biomarker combinations to identify Alzheimer´s disease at any stage along the AD continuum compared with both controls and non‐AD dementia

Author(s): James D Doecke, Giovanni Bellomo, Lisa Vermunt, Daniel Alcolea, Steffen Halbgebauer, Sjors G.J.G. in ’t Veld, Niklas Mattsson‐Carlgren, Katerina Veverova, Christopher J Fowler, Lynn Boonkamp, Marleen Koel‐Simmerlink, Zulaiga Hussainali, Daimy N. Ruiters, Lorenzo Gaetani, Andrea Toja, Juan Fortea, Yolande A.L. Pijnenburg, Afina W. Lemstra, Wiesje M. van der Flier, Jakub Hort, Markus Otto, Osk
Published in: Alzheimer's & Dementia, Issue 19, 2024, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.077504

Axonal injury in asymptomatic individuals preceding onset of multiple sclerosis

Author(s): Daniel Jons, Henrik Zetterberg, Martin Biström, Lucia Alonso‐Magdalena, Martin Gunnarsson, Magnus Vrethem, Kaj Blennow, Staffan Nilsson, Peter Sundström, Oluf Andersen
Published in: Annals of Clinical and Translational Neurology, Issue 9, 2023, Page(s) 882-887, ISSN 2328-9503
Publisher: WILEY
DOI: 10.1002/acn3.51568

Blood biomarkers for Alzheimer’s disease in clinical practice and trials

Author(s): Oskar Hansson, Kaj Blennow, Henrik Zetterberg, Jeffrey Dage
Published in: Nature Aging, Issue 3, 2023, Page(s) 506-519, ISSN 2662-8465
Publisher: SPRINGERNATURE
DOI: 10.1038/s43587-023-00403-3

Assessing the validity of a self-reported clinical diagnosis of schizophrenia

Author(s): Grace E. Woolway, Sophie E. Legge, Amy J. Lynham, Sophie E. Smart, Leon Hubbard, Ellie R. Daniel, Antonio F. Pardiñas, Valentina Escott-Price, Michael C. O’Donovan, Michael J. Owen, Ian R. Jones, James T. R. Walters
Published in: Schizophrenia, Issue 10, 2024, ISSN 2754-6993
Publisher: ELSEVIER - SCIENCE DIRECT
DOI: 10.1038/s41537-024-00526-5

Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer’s disease

Author(s): Hákon Valur Dansson, Lena Stempfle, Hildur Egilsdóttir, Alexander Schliep, Erik Portelius, Kaj Blennow, Henrik Zetterberg, Fredrik D. Johansson, null null
Published in: Alzheimer's Research & Therapy, Issue 13, 2023, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-021-00886-5

Cortisol, cognition and Alzheimer’s disease biomarkers among memory clinic patients

Author(s): Jasper Holleman, Sofia Adagunodo, Ingemar Kåreholt, Göran Hagman, Malin Aspö, Chinedu T Udeh-Momoh, Alina Solomon, Miia Kivipelto, Shireen Sindi
Published in: BMJ Neurology Open, Issue 4, 2024, Page(s) e000344, ISSN 2632-6140
Publisher: BMJ PUBLISHING GROUP
DOI: 10.1136/bmjno-2022-000344

An Automated Toolbox to Predict Single Subject Atrophy in Presymptomatic Granulin Mutation Carriers

Author(s): Enrico Premi, null null, Tommaso Costa, Stefano Gazzina, Alberto Benussi, Franco Cauda, Roberto Gasparotti, Silvana Archetti, Antonella Alberici, John C. van Swieten, Raquel Sanchez-Valle, Fermin Moreno, Isabel Santana, Robert Laforce, Simon Ducharme, Caroline Graff, Daniela Galimberti, Mario Masellis, Carmela Tartaglia, James B. Rowe, Elizabeth Finger, Fabrizio Tagliavini, Alexandre de Mendonça,
Published in: Journal of Alzheimer's Disease, Issue 86, 2025, Page(s) 205-218, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-215447

Spatial patterns of brain lesions assessed through covariance estimations of lesional voxels in multiple Sclerosis: The SPACE-MS technique

Author(s): Carmen Tur, Francesco Grussu, Floriana De Angelis, Ferran Prados, Baris Kanber, Alberto Calvi, Arman Eshaghi, Thalis Charalambous, Rosa Cortese, Declan T. Chard, Jeremy Chataway, Alan J. Thompson, Olga Ciccarelli, Claudia A.M. Gandini Wheeler-Kingshott
Published in: NeuroImage: Clinical, Issue 33, 2022, Page(s) 102904, ISSN 2213-1582
Publisher: Elsevier BV
DOI: 10.1016/j.nicl.2021.102904

MTE-NODDI: Multi-TE NODDI for disentangling non-T2-weighted signal fractions from compartment-specific T2 relaxation times

Author(s): Ting Gong, Qiqi Tong, Hongjian He, Yi Sun, Jianhui Zhong, Hui Zhang
Published in: NeuroImage, Issue 217, 2024, Page(s) 116906, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2020.116906

Confounding factors of Alzheimer's disease plasma biomarkers and their impact on clinical performance

Author(s): Alexa Pichet Binette, Shorena Janelidze, Nicholas Cullen, Jeffrey L. Dage, Randall J. Bateman, Henrik Zetterberg, Kaj Blennow, Erik Stomrud, Niklas Mattsson‐Carlgren, Oskar Hansson
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 1403-1414, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12787

Social activities in multidomain dementia prevention interventions: insights from practice and a blueprint for the future

Author(s): Jeroen Bruinsma, Leonie N. C. Visser, Alara Abaci, Anna Rosenberg, Ana Diaz, Sten Hanke, Rik Crutzen, Francesca Mangialasche, Miia Kivipelto, Charlotta Thunborg
Published in: Frontiers in Psychiatry, Issue 15, 2024, ISSN 1664-0640
Publisher: Frontiers Research Foundation
DOI: 10.3389/fpsyt.2024.1386688

Cytosolic stress granules relieve the ubiquitin‐proteasome system in the nuclear compartment

Author(s): Shanshan Xu, Maria E Gierisch, Anna Katharina Schellhaus, Ina Poser, Simon Alberti, Florian A Salomons, Nico P Dantuma
Published in: The EMBO Journal, Issue 42, 2023, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2022111802

Genetic variations in GBA1 and LRRK2 genes: Biochemical and clinical consequences in Parkinson disease

Author(s): Laura J. Smith, Chiao-Yin Lee, Elisa Menozzi, Anthony H. V. Schapira
Published in: Frontiers in Neurology, Issue 13, 2022, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2022.971252

Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores

Author(s): Ganna Leonenko, Emily Baker, Joshua Stevenson-Hoare, Annerieke Sierksma, Mark Fiers, Julie Williams, Bart de Strooper, Valentina Escott-Price
Published in: Nature Communications, Issue 12, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-24082-z

Plasma Aβ42/40 ratio, p‐tau181, GFAP, and NfL across the Alzheimer's disease continuum: A cross‐sectional and longitudinal study in the AIBL cohort

Author(s): Pratishtha Chatterjee, Steve Pedrini, James D. Doecke, Rohith Thota, Victor L. Villemagne, Vincent Doré, Abhay K. Singh, Penghao Wang, Stephanie Rainey‐Smith, Christopher Fowler, Kevin Taddei, Hamid R. Sohrabi, Mark P. Molloy, David Ames, Paul Maruff, Christopher C. Rowe, Colin L. Masters, Ralph N. Martins, null null
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 1117-1134, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12724

Differences between blood and cerebrospinal fluid glial fibrillary Acidic protein levels: The effect of sample stability

Author(s): Joel Simrén, Haley Weninger, Wagner S. Brum, Shilla Khalil, Andréa L. Benedet, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton
Published in: Alzheimer's & Dementia, Issue 18, 2023, Page(s) 1988-1992, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12806

Slowing gait speed precedes cognitive decline by several years

Author(s): Tobias Skillbäck, Kaj Blennow, Henrik Zetterberg, Johan Skoog, Lina Rydén, Hanna Wetterberg, Xinxin Guo, Simona Sacuiu, Michelle M. Mielke, Anna Zettergren, Ingmar Skoog, Silke Kern
Published in: Alzheimer's & Dementia, Issue 18, 2023, Page(s) 1667-1676, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12537

Brain-derived tau: a novel blood-based biomarker for Alzheimer’s disease-type neurodegeneration

Author(s): Fernando Gonzalez-Ortiz, Michael Turton, Przemysław R Kac, Denis Smirnov, Enrico Premi, Roberta Ghidoni, Luisa Benussi, Valentina Cantoni, Claudia Saraceno, Jasmine Rivolta, Nicholas J Ashton, Barbara Borroni, Douglas Galasko, Peter Harrison, Henrik Zetterberg, Kaj Blennow, Thomas K Karikari
Published in: Brain, Issue 146, 2023, Page(s) 1152-1165, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awac407

SLITRK2, an X-linked modifier of the age at onset in C9orf72 frontotemporal lobar degeneration

Author(s): Mathieu Barbier, Agnès Camuzat, Khalid El Hachimi, Justine Guegan, Daisy Rinaldi, Serena Lattante, Marion Houot, Raquel Sánchez-Valle, Mario Sabatelli, Anna Antonell, Laura Molina-Porcel, Fabienne Clot, Philippe Couratier, Emma van der Ende, Julie van der Zee, Claudia Manzoni, William Camu, Cécile Cazeneuve, François Sellal, Mira Didic, Véronique Golfier, Florence Pasquier, Charles Duyckaerts
Published in: Brain, Issue 144, 2021, Page(s) 2798-2811, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awab171

Genome-wide association studies for Alzheimer’s disease: bigger is not always better

Author(s): Valentina Escott-Price, John Hardy
Published in: Brain Communications, Issue 4, 2022, ISSN 2632-1297
Publisher: OXFOR UNIVERSITY PRESS
DOI: 10.1093/braincomms/fcac125

Association between ventricular CSF biomarkers and outcome after shunt surgery in idiopathic normal pressure hydrocephalus

Author(s): Rebecca Grønning, Anna Jeppsson, Per Hellström, Katarina Laurell, Dan Farahmand, Henrik Zetterberg, Kaj Blennow, Carsten Wikkelsø, Mats Tullberg
Published in: Fluids and Barriers of the CNS, Issue 20, 2023, ISSN 2045-8118
Publisher: BioMed Central
DOI: 10.1186/s12987-023-00475-8

Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer’s disease

Author(s): Marta Milà-Alomà, Nicholas J. Ashton, Mahnaz Shekari, Gemma Salvadó, Paula Ortiz-Romero, Laia Montoliu-Gaya, Andrea L. Benedet, Thomas K. Karikari, Juan Lantero-Rodriguez, Eugeen Vanmechelen, Theresa A. Day, Armand González-Escalante, Gonzalo Sánchez-Benavides, Carolina Minguillon, Karine Fauria, José Luis Molinuevo, Jeffrey L. Dage, Henrik Zetterberg, Juan Domingo Gispert, Marc Suárez-Calv
Published in: Nature Medicine, 2024, ISSN 1078-8956
Publisher: Nature Publishing Group
DOI: 10.1038/s41591-022-01925-w

Novel ultrasensitive immunoassay for the selective quantification of tau oligomers and related soluble aggregates

Author(s): Tohidul Islam, Hlin Kvartsberg, Anuradha Sehrawat, Przemysław R. Kac, Bruno Becker, Maria Olsson, Eric E. Abrahamson, Henrik Zetterberg, Milos D. Ikonomovic, Kaj Blennow, Thomas K. Karikari
Published in: Alzheimer's & Dementia, Issue 20, 2024, Page(s) 2894-2905, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13711

Mass spectrometric simultaneous quantification of tau species in plasma shows differential associations with amyloid and tau pathologies

Author(s): Laia Montoliu-Gaya, Andréa L. Benedet, Cécile Tissot, Agathe Vrillon, Nicholas J. Ashton, Wagner S. Brum, Juan Lantero-Rodriguez, Jenna Stevenson, Johanna Nilsson, Mathias Sauer, Nesrine Rahmouni, Gunnar Brinkmalm, Firoza Z. Lussier, Tharick A. Pascoal, Ingmar Skoog, Silke Kern, Henrik Zetterberg, Claire Paquet, Johan Gobom, Pedro Rosa-Neto, Kaj Blennow
Published in: Nature Aging, Issue 3, 2023, Page(s) 661-669, ISSN 2662-8465
Publisher: SPRINGERNATURE
DOI: 10.1038/s43587-023-00405-1

Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers

Author(s): Iris E. Jansen, Sven J. van der Lee, Duber Gomez-Fonseca, Itziar de Rojas, Maria Carolina Dalmasso, Benjamin Grenier-Boley, Anna Zettergren, Aniket Mishra, Muhammad Ali, Victor Andrade, Céline Bellenguez, Luca Kleineidam, Fahri Küçükali, Yun Ju Sung, Niccolo Tesí, Ellen M. Vromen, Douglas P. Wightman, Daniel Alcolea, Montserrat Alegret, Ignacio Alvarez, Philippe Amouyel, Lavinia Athanasiu, Sh
Published in: Acta Neuropathologica, Issue 144, 2022, Page(s) 821-842, ISSN 0001-6322
Publisher: Springer Verlag
DOI: 10.1007/s00401-022-02454-z

Neurofilament light oligomers in neurodegenerative diseases: quantification by homogeneous immunoassay in cerebrospinal fluid

Author(s): Francisco J. Meda, Kathryn Knowles, Imogen J. Swift, Aitana Sogorb-Esteve, Jonathan D. Rohrer, Anna Dittrich, Ingmar Skoog, Silke Kern, Bruno Becker, Kaj Blennow, Ulf Andreasson, Hlin Kvartsberg, Henrik Zetterberg
Published in: BMJ Neurology Open, Issue 5, 2024, Page(s) e000395, ISSN 2632-6140
Publisher: BMJ PUBLISHING GROUP- diamond open acces
DOI: 10.1136/bmjno-2022-000395

Validation of the LUMIPULSE automated immunoassay for the measurement of core AD biomarkers in cerebrospinal fluid

Author(s): Johan Gobom, Lucilla Parnetti, Pedro Rosa-Neto, Martin Vyhnalek, Serge Gauthier, Samuela Cataldi, Ondrej Lerch, Jan Laczo, Katerina Cechova, Marcus Clarin, Andrea L. Benet, Tharick A. Pascoal, Neserine Rahmouni, Manu Vandijck, Else Huyck, Nathalie Le Bastard, Jenna Stevenson, Mira Chamoun, Daniel Alcolea, Alberto Lleó, Ulf Andreasson, Marcel M. Verbeek, Giovanni Bellomo, Roberta Rinaldi, Nicholas
Published in: Clinical Chemistry and Laboratory Medicine (CCLM), Issue 60, 2023, Page(s) 207-219, ISSN 1434-6621
Publisher: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/cclm-2021-0651

Molecular atlas of the adult mouse brain

Author(s): Cantin Ortiz, Jose Fernandez Navarro, Aleksandra Jurek, Antje Märtin, Joakim Lundeberg, Konstantinos Meletis
Published in: Science Advances, Issue 6, 2024, ISSN 2375-2548
Publisher: AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/sciadv.abb3446

Plasma and CSF concentrations of N‐terminal tau fragments associate with in vivo neurofibrillary tangle burden

Author(s): Juan Lantero‐Rodriguez, Cécile Tissot, Anniina Snellman, Stijn Servaes, Andrea L. Benedet, Nesrine Rahmouni, Laia Montoliu‐Gaya, Joseph Therriault, Wagner S. Brum, Jenna Stevenson, Firoza Z. Lussier, Gleb Bezgin, Arthur C. Macedo, Mira Chamoun, Sulantha S. Mathotaarachi, Tharick A. Pascoal, Nicholas J. Ashton, Henrik Zetterberg, Pedro Rosa Neto, Kaj Blennow
Published in: Alzheimer's & Dementia, Issue 19, 2024, Page(s) 5343-5354, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13119

SCRN1: A cerebrospinal fluid biomarker correlating with tau in Alzheimer's disease

Author(s): Sophia Weiner, Mathias Sauer, Gunnar Brinkmalm, Julius Constantinescu, Radu Constantinescu, Bárbara Fernandes Gomes, Bruno Becker, Bengt Nellgård, Keti Dalla, Douglas Galasko, Henrik Zetterberg, Kaj Blennow, Johan Gobom
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 4609-4618, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13042

Drivers of Frailty from Adulthood into Old Age: Results from a 27-Year Longitudinal Population-Based Study in Sweden

Author(s): Emma Raymond, Chandra A Reynolds, Anna K Dahl Aslan, Deborah Finkel, Malin Ericsson, Sara Hägg, Nancy L Pedersen, Juulia Jylhävä
Published in: The Journals of Gerontology: Series A, Issue 75, 2020, Page(s) 1943-1950, ISSN 1079-5006
Publisher: Gerontological Society of America
DOI: 10.1093/gerona/glaa106

TREM2 is down-regulated by HSV1 in microglia and involved in antiviral defense in the brain

Author(s): Stefanie Fruhwürth, Line S. Reinert, Carl Öberg, Marcelina Sakr, Marcus Henricsson, Henrik Zetterberg, Søren R. Paludan
Published in: Science Advances, Issue 9, 2024, ISSN 2375-2548
Publisher: AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/sciadv.adf5808

Cynomolgus Monkeys With Spontaneous Type-2-Diabetes-Mellitus-Like Pathology Develop Alpha-Synuclein Alterations Reminiscent of Prodromal Parkinson’s Disease and Related Diseases

Author(s): Yan Sun, Chuang Guo, Lin Yuan, Wen Li, Zhan-You Wang, Feng Yue, Jia-Yi Li
Published in: Frontiers in Neuroscience, Issue 14, 2020, ISSN 1662-453X
Publisher: FRONTIERS MEDIA SA
DOI: 10.3389/fnins.2020.00063

Inter‐cohort staging efficacy of gaussian process progression model for Alzheimer’s disease

Author(s): Damiano Archetti, Marco Lorenzi, Neil P. Oxtoby, Daniel C. Alexander, Giovanni B. Frisoni, Alberto Redolfi
Published in: Alzheimer's & Dementia, Issue 16, 2023, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.043246

Association of genetic liability for psychiatric disorders with accelerometer-assessed physical activity in the UK Biobank

Author(s): Charlotte A. Dennison, Sophie E. Legge, Matthew Bracher-Smith, Georgina Menzies, Valentina Escott-Price, Daniel J. Smith, Aiden R. Doherty, Michael J. Owen, Michael C. O’Donovan, James T. R. Walters
Published in: PLOS ONE, Issue 16, 2021, Page(s) e0249189, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0249189

Moving fluid biomarkers for Alzheimer’s disease from research tools to routine clinical diagnostics

Author(s): Henrik Zetterberg, Kaj Blennow
Published in: Molecular Neurodegeneration, Issue 16, 2022, ISSN 1750-1326
Publisher: BioMed Central
DOI: 10.1186/s13024-021-00430-x

Clinical and analytical comparison of six Simoa assays for plasma P-tau isoforms P-tau181, P-tau217, and P-tau231

Author(s): Sherif Bayoumy, Inge M. W. Verberk, Ben den Dulk, Zulaiga Hussainali, Marissa Zwan, Wiesje M. van der Flier, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Jeffrey L. Dage, Charlotte E. Teunissen
Published in: Alzheimer's Research & Therapy, Issue 13, 2023, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-021-00939-9

Correlative Chemical Imaging Identifies Amyloid Peptide Signatures of Neuritic Plaques and Dystrophy in Human Sporadic Alzheimer's Disease

Author(s): Srinivas Koutarapu, Junyue Ge, Durga Jha, Kaj Blennow, Henrik Zetterberg, Tammaryn Lashley, Wojciech Michno, Jörg Hanrieder
Published in: Brain Connectivity, Issue 13, 2023, Page(s) 297-306, ISSN 2158-0014
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/brain.2022.0047

Perioperative brain injury marker concentrations in neonatal open-heart surgery: a prospective observational study

Author(s): Åsa Jungner, Finn Lennartsson, Isabella Björkman-Burtscher, Kaj Blennow, Henrik Zetterberg, David Ley
Published in: Frontiers in Pediatrics, Issue 11, 2023, ISSN 2296-2360
Publisher: FRONTIERS MEDIA SA
DOI: 10.3389/fped.2023.1186061

Cerebrospinal fluid proteomic study of two bipolar disorder cohorts

Author(s): Anniella Isgren, Andreas Göteson, Jessica Holmén-Larsson, Aurimantas Pelanis, Carl Sellgren, Erik Joas, Timea Sparding, Henrik Zetterberg, Erik Smedler, Joel Jakobsson, Mikael Landén
Published in: Molecular Psychiatry, Issue 27, 2023, Page(s) 4568-4574, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-022-01724-2

Cerebrospinal fluid biomarker panel for synaptic dysfunction in a broad spectrum of neurodegenerative diseases

Author(s): Johanna Nilsson, Alexa Pichet Binette, Sebastian Palmqvist, Wagner S Brum, Shorena Janelidze, Nicholas J Ashton, Nicola Spotorno, Erik Stomrud, Johan Gobom, Henrik Zetterberg, Ann Brinkmalm, Kaj Blennow, Oskar Hansson
Published in: Brain, Issue 147, 2024, Page(s) 2414-2427, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awae032

microRNA‐based predictor for diagnosis of frontotemporal dementia

Author(s): Iddo Magen, Nancy‐Sarah Yacovzada, Jason D. Warren, Carolin Heller, Imogen Swift, Yoana Bobeva, Andrea Malaspina, Jonathan D. Rohrer, Pietro Fratta, Eran Hornstein
Published in: Neuropathology and Applied Neurobiology, Issue 49, 2023, ISSN 0305-1846
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/nan.12916

Structural MRI predicts clinical progression in presymptomatic genetic frontotemporal dementia: findings from the GENetic Frontotemporal dementia Initiative cohort

Author(s): Martina Bocchetta, Emily G Todd, Arabella Bouzigues, David M Cash, Jennifer M Nicholas, Rhian S Convery, Lucy L Russell, David L Thomas, Ian B Malone, Juan Eugenio Iglesias, John C van Swieten, Lize C Jiskoot, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Raquel Sanchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Ro
Published in: Brain Communications, Issue 5, 2023, ISSN 2632-1297
Publisher: OXFORD UNIVERSITY PRESS
DOI: 10.1093/braincomms/fcad061

Cerebrospinal fluid amyloid precursor protein as a potential biomarker of fatigue in multiple sclerosis: A pilot study

Author(s): Kalle Johansson, Pontus Wasling, Lenka Novakova, Simon Sjödin, Ann Brinkmalm, Gunnar Brinkmalm, Kaj Blennow, Henrik Zetterberg, Markus Axelsson
Published in: Multiple Sclerosis and Related Disorders, Issue 63, 2022, Page(s) 103846, ISSN 2211-0348
Publisher: Elsevier
DOI: 10.1016/j.msard.2022.103846

Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases

Author(s): Michael Benatar, Joanne Wuu, Caroline McHutchison, Ronald B Postuma, Bradley F Boeve, Ronald Petersen, Christopher A Ross, Howard Rosen, Jalayne J Arias, Stephanie Fradette, Michael P McDermott, Jeremy Shefner, Christine Stanislaw, Sharon Abrahams, Stephanie Cosentino, Peter M Andersen, Richard S Finkel, Volkan Granit, Anne-Laure Grignon, Jonathan D Rohrer, Corey T McMillan, Murray Grossman, Ammar
Published in: Brain, Issue 145, 2022, Page(s) 27-44, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awab404

Transferability of Alzheimer's disease progression subtypes to an independent population cohort

Author(s): Hanyi Chen, Alexandra Young, Neil P. Oxtoby, Frederik Barkhof, Daniel C. Alexander, Andre Altmann
Published in: NeuroImage, Issue 271, 2023, Page(s) 120005, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2023.120005

The problematic syndrome of right temporal lobe atrophy: Unweaving the phenotypic rainbow

Author(s): Christopher R. S. Belder, Anthipa Chokesuwattanaskul, Charles R. Marshall, Chris J. D. Hardy, Jonathan D. Rohrer, Jason D. Warren
Published in: Frontiers in Neurology, Issue 13, 2023, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2022.1082828

β-Amyloid, Tau, Neurodegeneration Classification and Eligibility for Anti-amyloid Treatment in a Memory Clinic Population

Author(s): Anna Rosenberg, Ulf Öhlund-Wistbacka, Anette Hall, Alexandre Bonnard, Göran Hagman, Marie Rydén, Charlotta Thunborg, Fleur Wiggenraad, Anna Sandebring-Matton, Alina Solomon, Miia Kivipelto
Published in: Neurology, Issue 99, 2024, ISSN 0028-3878
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000201043

The effect of vitamin B supplementation on neuronal injury in people living with HIV: a randomized controlled trial

Author(s): Erika Tyrberg, Lars Hagberg, Lars-Magnus Andersson, Staffan Nilsson, Aylin Yilmaz, Åsa Mellgren, Kaj Blennow, Henrik Zetterberg, Magnus Gisslén
Published in: Brain Communications, Issue 4, 2022, ISSN 2632-1297
Publisher: OXFORD UNIV PRESS
DOI: 10.1093/braincomms/fcac259

Blood biomarkers for HIV infection with focus on neurologic complications—A review

Author(s): Lars Hagberg, Arvid Edén, Henrik Zetterberg, Richard W. Price, Magnus Gisslén
Published in: Acta Neurologica Scandinavica, Issue 146, 2022, Page(s) 56-60, ISSN 0001-6314
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ane.13629

Ap4b1-knockout mouse model of hereditary spastic paraplegia type 47 displays motor dysfunction, aberrant brain morphology and ATG9A mislocalization

Author(s): Joseph M Scarrott, João Alves-Cruzeiro, Paolo M Marchi, Christopher P Webster, Zih-Liang Yang, Evangelia Karyka, Raffaele Marroccella, Ian Coldicott, Hannah Thomas, Mimoun Azzouz
Published in: Brain Communications, Issue 5, 2024, ISSN 2632-1297
Publisher: OXFORD ACADEMIC - OXFORD UNIVERSITY PRESS
DOI: 10.1093/braincomms/fcac335

Biological variation estimates of Alzheimer's disease plasma biomarkers in healthy individuals

Author(s): Wagner S. Brum, Nicholas J. Ashton, Joel Simrén, Guiglielmo di Molfetta, Thomas K. Karikari, Andrea L. Benedet, Eduardo R. Zimmer, Juan Lantero‐Rodriguez, Laia Montoliu‐Gaya, Andreas Jeromin, Aasne K. Aarsand, William A. Bartlett, Pilar Fernández Calle, Abdurrahman Coşkun, Jorge Díaz–Garzón, Niels Jonker, Henrik Zetterberg, Sverre Sandberg, Anna Carobene, Kaj Blennow
Published in: Alzheimer's & Dementia, Issue 20, 2024, Page(s) 1284-1297, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13518

Overlapping brain correlates of superior cognition among children at genetic risk for Alzheimer’s disease and/or major depressive disorder

Author(s): Raluca Petrican, Amy L. Paine, Valentina Escott-Price, Katherine H. Shelton
Published in: Scientific Reports, Issue 13, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-28057-6

Utility of plasma neurofilament light and total tau for clinical trials in Alzheimer's disease

Author(s): Lars Lau Raket, Line Kühnel, Ellen Schmidt, Kaj Blennow, Henrik Zetterberg, Niklas Mattsson‐Carlgren
Published in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Issue 12, 2024, ISSN 2352-8729
Publisher: WILEY
DOI: 10.1002/dad2.12099

Biomarkers of Alzheimer's disease and neurodegeneration in dried blood spots—A new collection method for remote settings

Author(s): Hanna Huber, Kaj Blennow, Henrik Zetterberg, Mercé Boada, Andreas Jeromin, Haley Weninger, Raul Nuñez‐Llaves, Núria Aguilera, Maribel Ramis, Joel Simrén, Johanna Nilsson, Juan Lantero‐Rodriguez, Adelina Orellana, Fernando García‐Gutiérrez, Xavier Morató, Nicholas J. Ashton, Laia Montoliu‐Gaya
Published in: Alzheimer's & Dementia, Issue 20, 2024, Page(s) 2340-2352, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13697

Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer’s disease

Author(s): Joshua Stevenson-Hoare, Amanda Heslegrave, Ganna Leonenko, Dina Fathalla, Eftychia Bellou, Lauren Luckcuck, Rachel Marshall, Rebecca Sims, Bryan Paul Morgan, John Hardy, Bart de Strooper, Julie Williams, Henrik Zetterberg, Valentina Escott-Price
Published in: Brain, Issue 146, 2023, Page(s) 690-699, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awac128

Analysis of brain atrophy and local gene expression in genetic frontotemporal dementia

Author(s): Andre Altmann, David M Cash, Martina Bocchetta, Carolin Heller, Regina Reynolds, Katrina Moore, Rhian S Convery, David L Thomas, John C van Swieten, Fermin Moreno, Raquel Sanchez-Valle, Barbara Borroni, Robert Laforce, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Daniela Galimberti, James B Rowe, Elizabeth Finger, Matthis Synofzik, Rik Vandenberghe, Alexandre de Mendonça, Fabrizio Tag
Published in: Brain Communications, Issue 2, 2024, ISSN 2632-1297
Publisher: OXFORD UNIVERSITY PRESS
DOI: 10.1093/braincomms/fcaa122

Higher levels of neurofilament light chain and total tau in CSF are associated with negative outcome after shunt surgery in patients with normal pressure hydrocephalus

Author(s): Madelene Braun, Caroline Bjurnemark, Woosung Seo, Eva Freyhult, Dag Nyholm, Valter Niemelä, Kaj Blennow, Henrik Zetterberg, David Fällmar, Kim Kultima, Johan Virhammar
Published in: Fluids and Barriers of the CNS, Issue 19, 2022, ISSN 2045-8118
Publisher: BioMed Central
DOI: 10.1186/s12987-022-00306-2

A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study

Author(s): Sofia Bergström, Linn Öijerstedt, Julia Remnestål, Jennie Olofsson, Abbe Ullgren, Harro Seelaar, John C. van Swieten, Matthis Synofzik, Raquel Sanchez-Valle, Fermin Moreno, Elizabeth Finger, Mario Masellis, Carmela Tartaglia, Rik Vandenberghe, Robert Laforce, Daniela Galimberti, Barbara Borroni, Chris R. Butler, Alexander Gerhard, Simon Ducharme, Jonathan D. Rohrer, Anna Månberg, Caroline Graf
Published in: Molecular Neurodegeneration, Issue 16, 2021, ISSN 1750-1326
Publisher: BioMed Central
DOI: 10.1186/s13024-021-00499-4

Correction to: Probability of Alzheimer’s disease based on common and rare genetic variants

Author(s): Valentina Escott-Price, Karl Michael Schmidt
Published in: Alzheimer's Research & Therapy, Issue 13, 2021, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-021-00898-1

Perspectives on Care for Late-Stage Parkinson’s Disease

Author(s): Kristina Rosqvist, Marianne Kylberg, Charlotte Löfqvist, Anette Schrag, Per Odin, Susanne Iwarsson
Published in: Parkinson's Disease, Issue 2021, 2021, Page(s) 1-11, ISSN 2042-0080
Publisher: Hindawi Publishing Corporation
DOI: 10.1155/2021/9475026

Elevated CSF GAP-43 is associated with accelerated tau accumulation and spread in Alzheimer’s disease

Author(s): Nicolai Franzmeier, Amir Dehsarvi, Anna Steward, Davina Biel, Anna Dewenter, Sebastian Niclas Roemer, Fabian Wagner, Mattes Groß, Matthias Brendel, Alexis Moscoso, Prithvi Arunachalam, Kaj Blennow, Henrik Zetterberg, Michael Ewers, Michael Schöll
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-44374-w

Exposure to source-specific air pollution in residential areas and its association with dementia incidence: a cohort study in Northern Sweden

Author(s): Anna Oudin, Wasif Raza, Erin Flanagan, David Segersson, Pasi Jalava, Katja M. Kanninen, Topi Rönkkö, Rosalba Giugno, Thomas Sandström, Ala Muala, Jan Topinka, Johan Sommar
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-66166-y

Cerebrospinal fluid biomarker panel of synaptic dysfunction in Alzheimer's disease and other neurodegenerative disorders

Author(s): Johanna Nilsson, Katheryn A.Q. Cousins, Johan Gobom, Erik Portelius, Alice Chen‐Plotkin, Leslie M. Shaw, Murray Grossman, David J. Irwin, John Q. Trojanowski, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 1775-1784, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12809

Towards 3D Bioprinted Spinal Cord Organoids

Author(s): Yilin Han, Marianne King, Evgenii Tikhomirov, Povilas Barasa, Cleide Dos Santos Souza, Jonas Lindh, Daiva Baltriukiene, Laura Ferraiuolo, Mimoun Azzouz, Maurizio R. Gullo, Elena N. Kozlova
Published in: International Journal of Molecular Sciences, Issue 23, 2024, Page(s) 5788, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23105788

Identifying the neurodevelopmental and psychiatric signatures of genomic disorders associated with intellectual disability: a machine learning approach

Author(s): Nicholas Donnelly, Adam Cunningham, Sergio Marco Salas, Matthew Bracher-Smith, Samuel Chawner, Jan Stochl, Tamsin Ford, F. Lucy Raymond, Valentina Escott-Price, Marianne B. M. van den Bree
Published in: Molecular Autism, Issue 14, 2023, ISSN 2040-2392
Publisher: BioMed Central
DOI: 10.1186/s13229-023-00549-2

Biomarkers of Alzheimer’s Disease and Cerebrovascular Disease in Relation to Depressive Symptomatology in Individuals With Subjective Cognitive Decline

Author(s): Mariola Zapater-Fajarí, Patricia Diaz-Galvan, Nira Cedres, Therese Rydberg Sterner, Lina Rydén, Simona Sacuiu, Margda Waern, Anna Zettergren, Henrik Zetterberg, Kaj Blennow, Silke Kern, Vanesa Hidalgo, Alicia Salvador, Eric Westman, Ingmar Skoog, Daniel Ferreira
Published in: The Journals of Gerontology: Series A, Issue 79, 2024, ISSN 1079-5006
Publisher: Gerontological Society of America
DOI: 10.1093/gerona/glad216

Phenotypic effect of GBA1 variants in individuals with and without Parkinson's disease: The RAPSODI study

Author(s): Marco Toffoli, Harneek Chohan, Stephen Mullin, Aaron Jesuthasan, Selen Yalkic, Sofia Koletsi, Elisa Menozzi, Soraya Rahall, Naomi Limbachiya, Nadine Loefflad, Abigail Higgins, Jonathan Bestwick, Sara Lucas-Del-Pozo, Federico Fierli, Audrey Farbos, Roxana Mezabrovschi, Chiao Lee-Yin, Anette Schrag, David Moreno-Martinez, Derralynn Hughes, Alastair Noyce, Kevin Colclough, Aaron R. Jeffries, Christos
Published in: Neurobiology of Disease, Issue 188, 2023, Page(s) 106343, ISSN 0969-9961
Publisher: Academic Press
DOI: 10.1016/j.nbd.2023.106343

Intranasal administration of α-synuclein preformed fibrils triggers microglial iron deposition in the substantia nigra of Macaca fascicularis

Author(s): Jian-Jun Guo, Feng Yue, Dong-Yan Song, Luc Bousset, Xin Liang, Jing Tang, Lin Yuan, Wen Li, Ronald Melki, Yong Tang, Piu Chan, Chuang Guo, Jia-Yi Li
Published in: Cell Death & Disease, Issue 12, 2022, ISSN 2041-4889
Publisher: Nature Publishing Group
DOI: 10.1038/s41419-020-03369-x

Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers

Author(s): Niklas Mattsson-Carlgren, Gemma Salvadó, Nicholas J. Ashton, Pontus Tideman, Erik Stomrud, Henrik Zetterberg, Rik Ossenkoppele, Tobey J. Betthauser, Karly Alex Cody, Erin M. Jonaitis, Rebecca Langhough, Sebastian Palmqvist, Kaj Blennow, Shorena Janelidze, Sterling C. Johnson, Oskar Hansson
Published in: JAMA Neurology, Issue 80, 2023, Page(s) 360, ISSN 2168-6149
Publisher: American Medical Association
DOI: 10.1001/jamaneurol.2022.5272

Common risk alleles for schizophrenia within the major histocompatibility complex predict white matter microstructure

Author(s): Xavier Caseras, Emily Simmonds, Antonio F. Pardiñas, Richard Anney, Sophie E. Legge, James T. R. Walters, Neil A. Harrison, Michael C. O’Donovan, Valentina Escott-Price
Published in: Translational Psychiatry, Issue 14, 2024, ISSN 2158-3188
Publisher: Nature Publishing Group
DOI: 10.1038/s41398-024-02910-2

A Non-APOE Polygenic Risk Score for Alzheimer’s Disease Is Associated With Cerebrospinal Fluid Neurofilament Light in a Representative Sample of Cognitively Unimpaired 70-Year Olds

Author(s): Ingmar Skoog, Silke Kern, Jenna Najar, Rita Guerreiro, Jose Bras, Margda Waern, Henrik Zetterberg, Kaj Blennow, Anna Zettergren
Published in: The Journals of Gerontology: Series A, Issue 76, 2021, Page(s) 983-990, ISSN 1079-5006
Publisher: Gerontological Society of America
DOI: 10.1093/gerona/glab030

Increased plasma DOPA decarboxylase levels in Lewy body disorders are driven by dopaminergic treatment

Author(s): Katharina Bolsewig, Eline A. J. Willemse, Pascual Sánchez-Juan, Alberto Rábano, Minerva Martínez, James D. Doecke, Giovanni Bellomo, Lisa Vermunt, Daniel Alcolea, Steffen Halbgebauer, Sjors in ‘t Veld, Niklas Mattsson-Carlgren, Katerina Veverova, Christopher J. Fowler, Lynn Boonkamp, Marleen Koel-Simmelink, Zulaiga Hussainali, Daimy N. Ruiters, Lorenzo Gaetani, Andrea Toja, Juan Fortea, Yolan
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-56293-z

Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive Individuals

Author(s): Annika Öhrfelt, Andréa L. Benedet, Nicholas J. Ashton, Hlin Kvartsberg, Manu Vandijck, Michael W. Weiner, John Q. Trojanowski, Leslie M. Shaw, Henrik Zetterberg, Kaj Blennow, null null
Published in: Neurology, Issue 100, 2024, ISSN 0028-3878
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000201417

BolT: Fused window transformers for fMRI time series analysis

Author(s): Hasan A. Bedel, Irmak Sivgin, Onat Dalmaz, Salman U.H. Dar, Tolga Çukur
Published in: Medical Image Analysis, Issue 88, 2024, Page(s) 102841, ISSN 1361-8415
Publisher: Elsevier BV
DOI: 10.1016/j.media.2023.102841

Who is at Risk of Parkinson Disease? Refining the Preclinical Phase of GBA1 and LRRK2 Variant Carriers: a Clinical, Biochemical, and Imaging Approach

Author(s): Elisa Menozzi, Anthony H. V. Schapira, Fabio Blandini, Micol Avenali
Published in: Current Neurology and Neuroscience Reports, Issue 23, 2023, Page(s) 121-130, ISSN 1528-4042
Publisher: Current Science Inc.
DOI: 10.1007/s11910-023-01259-1

Advances and controversies in frontotemporal dementia: diagnosis, biomarkers, and therapeutic considerations

Author(s): Bradley F Boeve, Adam L Boxer, Fiona Kumfor, Yolande Pijnenburg, Jonathan D Rohrer
Published in: The Lancet Neurology, Issue 21, 2023, Page(s) 258-272, ISSN 1474-4422
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1474-4422(21)00341-0

Red Cell Distribution Width and Dementia Among Rural-Dwelling Older Adults: The MIND-China Study

Author(s): Ziying Jiang, Xiaolei Han, Yongxiang Wang, Tingting Hou, Lin Cong, Shi Tang, Xiaodong Han, Tiia Ngandu, Miia Kivipelto, Bengt Winblad, Lenore J. Launer, Yifeng Du, Chengxuan Qiu
Published in: Journal of Alzheimer's Disease, Issue 83, 2024, Page(s) 1187-1198, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-210517

GBA Variants and Parkinson Disease: Mechanisms and Treatments

Author(s): Laura Smith, Anthony H. V. Schapira
Published in: Cells, Issue 11, 2024, Page(s) 1261, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11081261

Lumbar and ventricular CSF concentrations of extracellular matrix proteins before and after shunt surgery in idiopathic normal pressure hydrocephalus

Author(s): Karolina Minta, Anna Jeppsson, Gunnar Brinkmalm, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Mats Tullberg, Ulf Andreasson
Published in: Fluids and Barriers of the CNS, Issue 18, 2021, ISSN 2045-8118
Publisher: BioMed Central
DOI: 10.1186/s12987-021-00256-1

Glucocerebrosidase mutations: A paradigm for neurodegeneration pathways

Author(s): Sophia R.L. Vieira, Anthony H.V. Schapira
Published in: Free Radical Biology and Medicine, Issue 175, 2023, Page(s) 42-55, ISSN 0891-5849
Publisher: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2021.08.230

Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia

Author(s): Jessica Gracias, Funda Orhan, Elin Hörbeck, Jessica Holmén-Larsson, Neda Khanlarkani, Susmita Malwade, Sravan K. Goparaju, Lilly Schwieler, İlknur Ş. Demirel, Ting Fu, Helena Fatourus-Bergman, Aurimantas Pelanis, Carleton P. Goold, Anneli Goulding, Kristina Annerbrink, Anniella Isgren, Timea Sparding, Martin Schalling, Viviana A. Carcamo Yañez, Jens C. Göpfert, Johanna Nilsson, Ann Brinkmalm
Published in: Nature Communications, Issue 13, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-33797-6

Blood neurofilament light in remote settings: Alternative protocols to support sample collection in challenging pre‐analytical conditions

Author(s): Joel Simrén, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg
Published in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Issue 13, 2023, ISSN 2352-8729
Publisher: WILEY
DOI: 10.1002/dad2.12145

Occupational complexity and cognition in the FINGER multidomain intervention trial

Author(s): Anders Rydström, Alexander Darin‐Mattsson, Ingemar Kåreholt, Tiia Ngandu, Jenni Lehtisalo, Alina Solomon, Riitta Antikainen, Lars Bäckman, Tuomo Hänninen, Tiina Laatikainen, Esko Levälahti, Jaana Lindström, Teemu Paajanen, Satu Havulinna, Markku Peltonen, Shireen Sindi, Hilkka Soininen, Anna Stigsdotter Neely, Timo Strandberg, Jaakko Tuomilehto, Miia Kivipelto, Francesca Mangialasche
Published in: Alzheimer's & Dementia, Issue 18, 2023, Page(s) 2438-2447, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12561

Diagnostic value of serum versus plasma phospho-tau for Alzheimer’s disease

Author(s): Przemysław R. Kac, Fernando Gonzalez-Ortiz, Joel Simrén, Nele Dewit, Eugeen Vanmechelen, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Thomas K. Karikari
Published in: Alzheimer's Research & Therapy, Issue 14, 2023, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-022-01011-w

Gut Microbiota Composition Is Related to AD Pathology

Author(s): Barbara J. H. Verhaar, Heleen M. A. Hendriksen, Francisca A. de Leeuw, Astrid S. Doorduijn, Mardou van Leeuwenstijn, Charlotte E. Teunissen, Frederik Barkhof, Philip Scheltens, Robert Kraaij, Cornelia M. van Duijn, Max Nieuwdorp, Majon Muller, Wiesje M. van der Flier
Published in: Frontiers in Immunology, Issue 12, 2022, ISSN 1664-3224
Publisher: Frontiers in Immunology
DOI: 10.3389/fimmu.2021.794519

Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer’s disease

Author(s): Joana B Pereira, Shorena Janelidze, Rik Ossenkoppele, Hlin Kvartsberg, Ann Brinkmalm, Niklas Mattsson-Carlgren, Erik Stomrud, Ruben Smith, Henrik Zetterberg, Kaj Blennow, Oskar Hansson
Published in: Brain, Issue 144, 2021, Page(s) 310-324, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awaa395

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Author(s): Alize J Ferrari, Damian Francesco Santomauro, Amirali Aali, Yohannes Habtegiorgis Abate, Cristiana Abbafati, Hedayat Abbastabar, Samar Abd ElHafeez, Michael Abdelmasseh, Sherief Abd-Elsalam, Arash Abdollahi, Auwal Abdullahi, Kedir Hussein Abegaz, Roberto Ariel Abeldaño Zuñiga, Richard Gyan Aboagye, Hassan Abolhassani, Lucas Guimarães Abreu, Hasan Abualruz, Eman Abu-Gharbieh, Niveen ME Abu-Rmeil
Published in: The Lancet, Issue 403, 2025, Page(s) 2133-2161, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(24)00757-8

Acute-Phase Neurofilament Light and Glial Fibrillary Acidic Proteins in Cerebrospinal Fluid Predict Long-Term Outcome After Severe Traumatic Brain Injury

Author(s): Emma Andersson, Martin Öst, Keti Dalla, Henrik Zetterberg, Kaj Blennow, Bengt Nellgård
Published in: Neurocritical Care, Issue 41, 2024, Page(s) 813-827, ISSN 1541-6933
Publisher: Humana Press, Inc.
DOI: 10.1007/s12028-024-01998-0

Interactions between dietary patterns and genetic factors in relation to incident dementia among 70-year-olds

Author(s): Jessica Samuelsson, Jenna Najar, Ola Wallengren, Silke Kern, Hanna Wetterberg, Madeleine Mellqvist Fässberg, Henrik Zetterberg, Kaj Blennow, Lauren Lissner, Elisabet Rothenberg, Ingmar Skoog, Anna Zettergren
Published in: European Journal of Nutrition, Issue 61, 2022, Page(s) 871-884, ISSN 1436-6207
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00394-021-02688-9

Thioflavin T─a Reporter of Microviscosity in Protein Aggregation Process: The Study Case of α-Synuclein

Author(s): Konstantin Rusakov, Aadil El-Turabi, Lasse Reimer, Poul Henning Jensen, Piotr Hanczyc
Published in: The Journal of Physical Chemistry Letters, Issue 15, 2024, Page(s) 6685-6690, ISSN 1948-7185
Publisher: American Chemical Society
DOI: 10.1021/acs.jpclett.4c00699

Clinical stage and plasma neurofilament concentration in adults with Friedreich ataxia

Author(s): Magnus Johnsson, Henrik Zetterberg, Kaj Blennow, Christopher Lindberg
Published in: Heliyon, Issue 10, 2025, Page(s) e23347, ISSN 2405-8440
Publisher: CELL PRESS
DOI: 10.1016/j.heliyon.2023.e23347

Altered plasma protein profiles in genetic FTD – a GENFI study

Author(s): Abbe Ullgren, Linn Öijerstedt, Jennie Olofsson, Sofia Bergström, Julia Remnestål, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Barbara Borroni, Raquel Sanchez-Valle, Fermin Moreno, Robert Laforce, Matthis Synofzik, Daniela Galimberti, James B. Rowe, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Finger, Rik Vandenberghe, Alexandre de Mendonça, Pietro Tirabosch, Isabel Santana, Simo
Published in: Molecular Neurodegeneration, Issue 18, 2023, ISSN 1750-1326
Publisher: BioMed Central
DOI: 10.1186/s13024-023-00677-6

Data‐driven staging of genetic frontotemporal dementia using multi‐modal <scp>MRI</scp>

Author(s): Jillian McCarthy, Barbara Borroni, Raquel Sanchez‐Valle, Fermin Moreno, Robert Laforce, Caroline Graff, Matthis Synofzik, Daniela Galimberti, James B. Rowe, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Finger, Rik Vandenberghe, Alexandre de Mendonça, Fabrizio Tagliavini, Isabel Santana, Chris Butler, Alex Gerhard, Adrian Danek, Johannes Levin, Markus Otto, Giovanni Frisoni, Roberta Ghidon
Published in: Human Brain Mapping, Issue 43, 2023, Page(s) 1821-1835, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25727

Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer’s disease

Author(s): Shorena Janelidze, Divya Bali, Nicholas J Ashton, Nicolas R Barthélemy, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Yingxin He, Anna Orduña Dolado, Gallen Triana-Baltzer, Michael J Pontecorvo, Henrik Zetterberg, Hartmuth Kolb, Manu Vandijck, Kaj Blennow, Randall J Bateman, Oskar Hansson
Published in: Brain, Issue 146, 2023, Page(s) 1592-1601, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awac333

Whole-genome sequencing analysis of semi-supercentenarians

Author(s): Paolo Garagnani, Julien Marquis, Massimo Delledonne, Chiara Pirazzini, Elena Marasco, Katarzyna Malgorzata Kwiatkowska, Vincenzo Iannuzzi, Maria Giulia Bacalini, Armand Valsesia, Jerome Carayol, Frederic Raymond, Alberto Ferrarini, Luciano Xumerle, Sebastiano Collino, Daniela Mari, Beatrice Arosio, Martina Casati, Evelyn Ferri, Daniela Monti, Benedetta Nacmias, Sandro Sorbi, Donata Luiselli, David
Published in: eLife, Issue 10, 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.57849

Single-cell multimodal analysis in a case with reduced penetrance of Progranulin-Frontotemporal Dementia

Author(s): Karthick Natarajan, Jesper Eisfeldt, Maria Hammond, José Miguel Laffita-Mesa, Kalicharan Patra, Behzad Khoshnood, Linn Öijerstedt, Caroline Graff
Published in: Acta Neuropathologica Communications, Issue 9, 2021, ISSN 2051-5960
Publisher: BioMed Central
DOI: 10.1186/s40478-021-01234-2

Autonomic ganglionic injection of α-synuclein fibrils as a model of pure autonomic failure α-synucleinopathy

Author(s): Xue-Jing Wang, Ming-Ming Ma, Le-Bo Zhou, Xiao-Yi Jiang, Miao-Miao Hao, Robert K. F. Teng, Erxi Wu, Bei-Sha Tang, Jia-Yi Li, Jun-Fang Teng, Xue-Bing Ding
Published in: Nature Communications, Issue 11, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-14189-9

Music in Care Home Settings: Guidelines for Implementation and Evaluation Based on the Music Interventions for Depression and Dementia in ELderly Care (MIDDEL) Study in the UK

Author(s): Justine Schneider, Joanne Ablewhite, Jodie Bloska, Christian Gold, Martin Orrell, Becky Dowson, Cliff McArdle, Helen Tooth, Sarah Trevers, Smruthi Murali Narippatta, Yin Fan, Jo Dugstad Wake, Agi Peach, Barbara Duckworth, Vigdis Sveinsdottir
Published in: Journal of Long-Term Care, 2024, ISSN 2516-9122
Publisher: LSE PRESS
DOI: 10.31389/jltc.294

Characterization of local white matter microstructural alterations in Alzheimer’s disease: A reproducible study

Author(s): Caiyun Wen, Qingrun Zeng, Ronghui Zhou, Lei Xie, Jiangli Yu, Chengzhe Zhang, Jingqiang Wang, Yan Yu, Yixin Gu, Guoquan Cao, Yuanjing Feng, Meihao Wang
Published in: Computers in Biology and Medicine, Issue 179, 2025, Page(s) 108750, ISSN 0010-4825
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2024.108750

High-yield Production of Amyloid-β Peptide Enabled by a Customized Spider Silk Domain

Author(s): Axel Abelein, Gefei Chen, Kristīne Kitoka, Rihards Aleksis, Filips Oleskovs, Médoune Sarr, Michael Landreh, Jens Pahnke, Kerstin Nordling, Nina Kronqvist, Kristaps Jaudzems, Anna Rising, Jan Johansson, Henrik Biverstål
Published in: Scientific Reports, Issue 10, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-57143-x

Microglial activation protects against accumulation of tau aggregates in nondemented individuals with underlying Alzheimer’s disease pathology

Author(s): Joana B. Pereira, Shorena Janelidze, Olof Strandberg, Christopher D. Whelan, Henrik Zetterberg, Kaj Blennow, Sebastian Palmqvist, Erik Stomrud, Niklas Mattsson-Carlgren, Oskar Hansson
Published in: Nature Aging, Issue 2, 2022, Page(s) 1138-1144, ISSN 2662-8465
Publisher: SPRINGERNATURE
DOI: 10.1038/s43587-022-00310-z

Dynamics and prognostic value of serum neurofilament light chain in Guillain-Barré syndrome

Author(s): Sander J. van Tilburg, Charlotte E. Teunissen, Carolien C.H.M. Maas, Robin C.M. Thomma, Christa Walgaard, Hans Heijst, Ruth Huizinga, Pieter A. van Doorn, Bart C. Jacobs
Published in: eBioMedicine, Issue 102, 2025, Page(s) 105072, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2024.105072

Increased immune activation and signs of neuronal injury in HIV-negative people on preexposure prophylaxis

Author(s): Josefina Robertson, Arvid Edén, Kristina Nyström, Lars Hagberg, Aylin Yilmaz, Johanna M. Gostner, Dietmar Fuchs, Staffan Nilsson, Kaj Blennow, Henrik Zetterberg, Magnus Gisslén
Published in: AIDS, Issue 35, 2024, Page(s) 2129-2136, ISSN 0269-9370
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/qad.0000000000002980

Author(s): Sergi Borrego-Écija, Roser Sala-Llonch, John van Swieten, Barbara Borroni, Fermín Moreno, Mario Masellis, Carmela Tartaglia, Caroline Graff, Daniela Galimberti, Robert Laforce, James B Rowe, Elizabeth Finger, Rik Vandenberghe, Fabrizio Tagliavini, Alexandre de Mendonça, Isabel Santana, Matthis Synofzik, Simon Ducharme, Johannes Levin, Adrian Danek, Alex Gerhard, Markus Otto, Chris Butler, Giova
Published in: NeuroImage: Clinical, Issue 29, 2022, Page(s) 102540, ISSN 2213-1582
Publisher: Elsevier BV
DOI: 10.1016/j.nicl.2020.102540

Neurofilament light, glial fibrillary acidic protein, and tau in a regional epilepsy cohort: High plasma levels are rare but related to seizures

Author(s): Sarah Akel, Fredrik Asztely, Rakesh Kumar Banote, Markus Axelsson, Henrik Zetterberg, Johan Zelano
Published in: Epilepsia, Issue 64, 2023, Page(s) 2690-2700, ISSN 0013-9580
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/epi.17713

Alzheimer Disease Blood Biomarkers in Patients With Out-of-Hospital Cardiac Arrest

Author(s): Nicholas J. Ashton, Marion Moseby-Knappe, Andrea L. Benedet, Lana Grötschel, Juan Lantero-Rodriguez, Thomas K. Karikari, Christian Hassager, Matt P. Wise, Pascal Stammet, Jesper Kjaergaard, Hans Friberg, Niklas Nielsen, Tobias Cronberg, Henrik Zetterberg, Kaj Blennow
Published in: JAMA Neurology, Issue 80, 2023, Page(s) 388, ISSN 2168-6149
Publisher: American Medical Association
DOI: 10.1001/jamaneurol.2023.0050

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases

Author(s): Niamh M. C. Connolly, Pierre Theurey, Vera Adam-Vizi, Nicolas G. Bazan, Paolo Bernardi, Juan P. Bolaños, Carsten Culmsee, Valina L. Dawson, Mohanish Deshmukh, Michael R. Duchen, Heiko Düssmann, Gary Fiskum, Maria F. Galindo, Giles E. Hardingham, J. Marie Hardwick, Mika B. Jekabsons, Elizabeth A. Jonas, Joaquin Jordán, Stuart A. Lipton, Giovanni Manfredi, Mark P. Mattson, BethAnn McLaughlin, Axe
Published in: Cell Death & Differentiation, Issue 25, 2023, Page(s) 542-572, ISSN 1350-9047
Publisher: Nature Publishing Group
DOI: 10.1038/s41418-017-0020-4

A data-driven study of Alzheimer's disease related amyloid and tau pathology progression

Author(s): Leon M Aksman, Neil P Oxtoby, Marzia A Scelsi, Peter A Wijeratne, Alexandra L Young, Isadora Lopes Alves, Lyduine E Collij, Jacob W Vogel, Frederik Barkhof, Daniel C Alexander, Andre Altmann, null null
Published in: Brain, Issue 146, 2023, Page(s) 4935-4948, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awad232

Proof-of-concept recall-by-genotype study of extremely low and high Alzheimer’s polygenic risk reveals autobiographical deficits and cingulate cortex correlates

Author(s): Thomas Lancaster, Byron Creese, Valentina Escott-Price, Ian Driver, Georgina Menzies, Zunera Khan, Anne Corbett, Clive Ballard, Julie Williams, Kevin Murphy, Hannah Chandler
Published in: Alzheimer's Research & Therapy, Issue 15, 2023, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-023-01362-y

Quantification of SNAP-25 with mass spectrometry and Simoa: a method comparison in Alzheimer’s disease

Author(s): Johanna Nilsson, Nicholas J. Ashton, Andrea L. Benedet, Laia Montoliu-Gaya, Johan Gobom, Tharick A. Pascoal, Mira Chamoun, Erik Portelius, Andreas Jeromin, Muriel Mendes, Henrik Zetterberg, Pedro Rosa-Neto, Ann Brinkmalm, Kaj Blennow
Published in: Alzheimer's Research & Therapy, Issue 14, 2022, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-022-01021-8

An efficient semi-supervised quality control system trained using physics-based MRI-artefact generators and adversarial training

Author(s): Daniele Ravi, Frederik Barkhof, Daniel C. Alexander, Lemuel Puglisi, Geoffrey J.M. Parker, Arman Eshaghi
Published in: Medical Image Analysis, Issue 91, 2024, Page(s) 103033, ISSN 1361-8415
Publisher: Elsevier BV
DOI: 10.1016/j.media.2023.103033

Machine learning for the life-time risk prediction of Alzheimer’s disease: a systematic review

Author(s): Thomas W Rowe, Ioanna K Katzourou, Joshua O Stevenson-Hoare, Matthew R Bracher-Smith, Dobril K Ivanov, Valentina Escott-Price
Published in: Brain Communications, Issue 3, 2021, ISSN 2632-1297
Publisher: OXFORD UNIVERSITY PRESS
DOI: 10.1093/braincomms/fcab246

A Nonlinear Relation between Body Mass Index and Long-Term Poststroke Functional Outcome—The Importance of Insulin Resistance, Inflammation, and Insulin-like Growth Factor-Binding Protein-1

Author(s): Gustaf Gadd, Daniel Åberg, Alexander Wall, Henrik Zetterberg, Kaj Blennow, Katarina Jood, Christina Jern, Jörgen Isgaard, Johan Svensson, N. David Åberg
Published in: International Journal of Molecular Sciences, Issue 25, 2025, Page(s) 4931, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25094931

Dementia prevention: The potential long‐term cost‐effectiveness of the FINGER prevention program

Author(s): Anders Wimo, Ron Handels, Riitta Antikainen, Maria Eriksdotter, Linus Jönsson, Martin Knapp, Jenni Kulmala, Tiina Laatikainen, Jenni Lehtisalo, Markku Peltonen, Anders Sköldunger, Hilkka Soininen, Alina Solomon, Timo Strandberg, Jaakko Tuomilehto, Tiia Ngandu, Miia Kivipelto
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 999-1008, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12698

Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol

Author(s): Beatriz Padrela, Amnah Mahroo, Mervin Tee, Markus H Sneve, Paulien Moyaert, Oliver Geier, Joost P A Kuijer, Soetkin Beun, Wibeke Nordhøy, Yufei David Zhu, Mareike A Buck, Daniel C Hoinkiss, Simon Konstandin, Jörn Huber, Julia Wiersinga, Roos Rikken, Diederick de Leeuw, Håkon Grydeland, Lynette Tippett, Erin E Cawston, Esin Ozturk-Isik, Jennifer Linn, Moritz Brandt, Betty M Tijms, Elsmarieke M v
Published in: BMJ Open, Issue 14, 2024, Page(s) e081635, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2023-081635

Proportion of Community-Dwelling Individuals Older Than 70 Years Eligible for Lecanemab Initiation

Author(s): Anna Dittrich, Eric Westman, Sara Shams, Tobias Skillbäck, Henrik Zetterberg, Kaj Blennow, Anna Zettergren, Ingmar Skoog, Silke Kern
Published in: Neurology, Issue 102, 2024, ISSN 0028-3878
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000209402

Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum

Author(s): Andréa L. Benedet, Marta Milà-Alomà, Agathe Vrillon, Nicholas J. Ashton, Tharick A. Pascoal, Firoza Lussier, Thomas K. Karikari, Claire Hourregue, Emmanuel Cognat, Julien Dumurgier, Jenna Stevenson, Nesrine Rahmouni, Vanessa Pallen, Nina M. Poltronetti, Gemma Salvadó, Mahnaz Shekari, Gregory Operto, Juan Domingo Gispert, Carolina Minguillon, Karine Fauria, Gwendlyn Kollmorgen, Ivonne Suridjan,
Published in: JAMA Neurology, Issue 78, 2021, Page(s) 1471, ISSN 2168-6149
Publisher: American Medical Association
DOI: 10.1001/jamaneurol.2021.3671

Abilities of the BRICHOS domain to prevent neurotoxicity and fibril formation are dependent on a highly conserved Asp residue

Author(s): Gefei Chen, Yuniesky Andrade-Talavera, Xueying Zhong, Sameer Hassan, Henrik Biverstål, Helen Poska, Axel Abelein, Axel Leppert, Nina Kronqvist, Anna Rising, Hans Hebert, Philip J. B. Koeck, André Fisahn, Jan Johansson
Published in: RSC Chemical Biology, Issue 3, 2024, Page(s) 1342-1358, ISSN 2633-0679
Publisher: ROYAL SOC CHEMISTRY
DOI: 10.1039/d2cb00187j

Synaptic Molecular and Neurophysiological Markers Are Independent Predictors of Progression in Alzheimer’s Disease

Author(s): Una Smailovic, Ingemar Kåreholt, Thomas Koenig, Nicholas J. Ashton, Bengt Winblad, Kina Höglund, Per Nilsson, Henrik Zetterberg, Kaj Blennow, Vesna Jelic
Published in: Journal of Alzheimer's Disease, Issue 83, 2024, Page(s) 355-366, ISSN 1387-2877
Publisher: IOS Press
DOI: 10.3233/jad-201234

Biomarkers of brain injury in patients with stress-related exhaustion: A longitudinal study

Author(s): Caroline Hansson, Henrik Zetterberg, Anniina Snellman, Kaj Blennow, Ingibjörg H. Jonsdottir
Published in: Psychoneuroendocrinology, Issue 146, 2022, Page(s) 105929, ISSN 0306-4530
Publisher: Pergamon Press
DOI: 10.1016/j.psyneuen.2022.105929

TBK1 haploinsufficiency results in changes in the K63-ubiquitination profiles in brain and fibroblasts from affected and presymptomatic mutation carriers

Author(s): Behzad Khoshnood, Abbe Ullgren, Jose Laffita-Mesa, Linn Öijerstedt, Kalicharan Patra, Inger Nennesmo, Caroline Graff
Published in: Journal of Neurology, Issue 269, 2022, Page(s) 3037-3049, ISSN 0340-5354
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-021-10887-x

Patterns of inflammation, microstructural alterations, and sodium accumulation define multiple sclerosis subtypes after 15 years from onset

Author(s): Antonio Ricciardi, Francesco Grussu, Baris Kanber, Ferran Prados, Marios C. Yiannakas, Bhavana S. Solanky, Frank Riemer, Xavier Golay, Wallace Brownlee, Olga Ciccarelli, Daniel C. Alexander, Claudia A. M. Gandini Wheeler-Kingshott
Published in: Frontiers in Neuroinformatics, Issue 17, 2023, ISSN 1662-5196
Publisher: Frontiers Research Foundation
DOI: 10.3389/fninf.2023.1060511

The Bacterial Amyloids Phenol Soluble Modulins from Staphylococcus aureus Catalyze Alpha-Synuclein Aggregation

Author(s): Caroline Haikal, Lei Ortigosa-Pascual, Zahra Najarzadeh, Katja Bernfur, Alexander Svanbergsson, Daniel E. Otzen, Sara Linse, Jia-Yi Li
Published in: International Journal of Molecular Sciences, Issue 22, 2025, Page(s) 11594, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222111594

Next-generation proteomics technologies in Alzheimer’s disease: from clinical research to routine diagnostics

Author(s): Sophia Weiner, Kaj Blennow, Henrik Zetterberg, Johan Gobom
Published in: Expert Review of Proteomics, Issue 20, 2023, Page(s) 143-150, ISSN 1478-9450
Publisher: Future Drugs Ltd.
DOI: 10.1080/14789450.2023.2255752

Effects of amyloid pathology and the APOE ε4 allele on the association between cerebrospinal fluid Aβ38 and Aβ40 and brain morphology in cognitively normal 70-years-olds

Author(s): Olof Lindberg, Silke Kern, Johan Skoog, Alejandra Machado, Joana B. Pereira, Simona F. Sacuiu, Lars-Olof Wahlund, Kaj Blennow, Henrik Zetterberg, Anna Zettergren, Eric Westman, Ingmar Skoog
Published in: Neurobiology of Aging, Issue 101, 2021, Page(s) 1-12, ISSN 0197-4580
Publisher: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2020.10.033

Investigating neurodegenerative heterogeneity in cognitively unimpaired A4 pre‐randomization cohort

Author(s): Cameron Shand, Michael C. Donohue, Neil P Oxtoby
Published in: Alzheimer's & Dementia, Issue 18, 2023, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.061456

Cerebral biomarkers in neurologic complications of preeclampsia

Author(s): Lina Bergman, Roxanne Hastie, Emma Bokström-Rees, Henrik Zetterberg, Kaj Blennow, Sonja Schell, Henrik Imberg, Eduard Langenegger, Ashley Moodley, Susan Walker, Stephen Tong, Catherine Cluver
Published in: American Journal of Obstetrics and Gynecology, Issue 227, 2022, Page(s) 298.e1-298.e10, ISSN 0002-9378
Publisher: Mosby Inc.
DOI: 10.1016/j.ajog.2022.02.036

Plasma interferon-alpha is associated with double-positivity for autoantibodies but is not a predictor of remission in early rheumatoid arthritis—a spin-off study of the NORD-STAR randomized clinical trial

Author(s): Marit Stockfelt, Anna-Carin Lundell, Merete Lund Hetland, Mikkel Østergaard, Till Uhlig, Marte Schrumpf Heiberg, Espen A. Haavardsholm, Michael T. Nurmohamed, Jon Lampa, Dan Nordström, Kim Hørslev Petersen, Bjorn Gudbjornsson, Gerdur Gröndal, Jonathan Aldridge, Kerstin Andersson, Kaj Blennow, Henrik Zetterberg, Ronald van Vollenhoven, Anna Rudin
Published in: Arthritis Research & Therapy, Issue 23, 2021, ISSN 1478-6362
Publisher: BMC
DOI: 10.1186/s13075-021-02556-1

Combining plasma phospho-tau and accessible measures to evaluate progression to Alzheimer’s dementia in mild cognitive impairment patients

Author(s): Alexa Pichet Binette, Sebastian Palmqvist, Divya Bali, Gill Farrar, Christopher J. Buckley, David A. Wolk, Henrik Zetterberg, Kaj Blennow, Shorena Janelidze, Oskar Hansson
Published in: Alzheimer's Research & Therapy, Issue 14, 2022, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-022-00990-0

Intrathecal kappa free light chain synthesis is associated with worse prognosis in relapsing–remitting multiple sclerosis

Author(s): Igal Rosenstein, Markus Axelsson, Lenka Novakova, Clas Malmeström, Kaj Blennow, Henrik Zetterberg, Jan Lycke
Published in: Journal of Neurology, Issue 270, 2023, Page(s) 4800-4811, ISSN 0340-5354
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-023-11817-9

Comparative analysis of multimodal biomarkers for amyloid-beta positivity detection in Alzheimer's disease cohorts

Author(s): Mostafa Mehdipour Ghazi, Per Selnes, Santiago Timón-Reina, Sandra Tecelão, Silvia Ingala, Atle Bjørnerud, Bjørn-Eivind Kirsebom, Tormod Fladby, Mads Nielsen
Published in: Frontiers in Aging Neuroscience, Issue 16, 2024, ISSN 1663-4365
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnagi.2024.1345417

Human-derived air–liquid interface cultures decipher Alzheimer’s disease–SARS-CoV-2 crosstalk in the olfactory mucosa

Author(s): Muhammad Ali Shahbaz, Suvi Kuivanen, Riikka Lampinen, Laura Mussalo, Tomáš Hron, Táňa Závodná, Ravi Ojha, Zdeněk Krejčík, Liudmila Saveleva, Numan Ahmad Tahir, Juho Kalapudas, Anne M. Koivisto, Elina Penttilä, Heikki Löppönen, Prateek Singh, Jan Topinka, Olli Vapalahti, Sweelin Chew, Giuseppe Balistreri, Katja M. Kanninen
Published in: Journal of Neuroinflammation, Issue 20, 2023, ISSN 1742-2094
Publisher: BioMed Central
DOI: 10.1186/s12974-023-02979-4

Multi‐cohort profiling reveals elevated CSF levels of brain‐enriched proteins in Alzheimer’s disease

Author(s): Sofia Bergström, Julia Remnestål, Jamil Yousef, Jennie Olofsson, Ioanna Markaki, Stephanie Carvalho, Jean‐Christophe Corvol, Kim Kultima, Lena Kilander, Malin Löwenmark, Martin Ingelsson, Kaj Blennow, Henrik Zetterberg, Bengt Nellgård, Frederic Brosseron, Michael T. Heneka, Beatriz Bosch, Raquel Sanchez‐Valle, Anna Månberg, Per Svenningsson, Peter Nilsson
Published in: Annals of Clinical and Translational Neurology, Issue 8, 2024, Page(s) 1456-1470, ISSN 2328-9503
Publisher: WILEY
DOI: 10.1002/acn3.51402

The Impact of Air Pollution Exposure on the MicroRNA Machinery and Lung Cancer Development

Author(s): Michal Sima, Andrea Rossnerova, Zuzana Simova, Pavel Rossner
Published in: Journal of Personalized Medicine, Issue 11, 2025, Page(s) 60, ISSN 2075-4426
Publisher: MDPI
DOI: 10.3390/jpm11010060

Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning

Author(s): William J Scotton, Cameron Shand, Emily Todd, Martina Bocchetta, David M Cash, Lawren VandeVrede, Hilary Heuer, null null, Alyssa A Costantini, Henry Houlden, Christopher Kobylecki, Michele T M Hu, Nigel Leigh, Bradley F Boeve, Brad C Dickerson, Carmela M Tartaglia, Irene Litvan, Murray Grossman, Alex Pantelyat, Edward D Huey, David J Irwin, Anne Fagan, Suzanne L Baker, Arthur W Toga, Alexandra L
Published in: Brain Communications, Issue 5, 2023, ISSN 2632-1297
Publisher: Brain communications
DOI: 10.1093/braincomms/fcad048

CT‐based volumetric measures obtained through deep learning: Association with biomarkers of neurodegeneration

Author(s): Meera Srikrishna, Nicholas J. Ashton, Alexis Moscoso, Joana B. Pereira, Rolf A. Heckemann, Danielle van Westen, Giovanni Volpe, Joel Simrén, Anna Zettergren, Silke Kern, Lars‐Olof Wahlund, Bibek Gyanwali, Saima Hilal, Joyce Chong Ruifen, Henrik Zetterberg, Kaj Blennow, Eric Westman, Christopher Chen, Ingmar Skoog, Michael Schöll
Published in: Alzheimer's & Dementia, Issue 20, 2024, Page(s) 629-640, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.13445

Disruption of sleep macro- and microstructure in Alzheimer’s disease: overlaps between neuropsychology, neurophysiology, and neuroimaging

Author(s): Anna Csilla Kegyes-Brassai, Robert Pierson-Bartel, Gergo Bolla, Anita Kamondi, Andras Attila Horvath
Published in: GeroScience, 2024, ISSN 2509-2723
Publisher: Springer Nature
DOI: 10.1007/s11357-024-01357-z

Human herpesvirus 6A and axonal injury before the clinical onset of multiple sclerosis

Author(s): Viktor Grut, Martin Biström, Jonatan Salzer, Pernilla Stridh, Daniel Jons, Rasmus Gustafsson, Anna Fogdell-Hahn, Jesse Huang, Julia Butt, Anna Lindam, Lucia Alonso-Magdalena, Tomas Bergström, Ingrid Kockum, Tim Waterboer, Tomas Olsson, Henrik Zetterberg, Kaj Blennow, Oluf Andersen, Staffan Nilsson, Peter Sundström
Published in: Brain, Issue 147, 2024, Page(s) 177-185, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awad374

Hierarchical spectral clustering reveals brain size and shape changes in asymptomatic carriers ofC9orf72

Author(s): Rose Bruffaerts, Dorothy Gors, Alicia Bárcenas Gallardo, Mathieu Vandenbulcke, Philip Van Damme, Paul Suetens, John C van Swieten, Barbara Borroni, Raquel Sanchez-Valle, Fermin Moreno, Robert Laforce, Caroline Graff, Matthis Synofzik, Daniela Galimberti, James B Rowe, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Finger, Alexandre de Mendonça, Fabrizio Tagliavini, Chris R Butler, Isabel San
Published in: Brain Communications, Issue 4, 2024, ISSN 2632-1297
Publisher: OXFORD UNIVERSITY PRESS
DOI: 10.1093/braincomms/fcac182

Delivery of therapeutic AAV9 vectors via cisterna magna to treat neurological disorders

Author(s): Paolo M. Marchi, Lara Marrone, Mimoun Azzouz
Published in: Trends in Molecular Medicine, Issue 28, 2024, Page(s) 79-80, ISSN 1471-4914
Publisher: Elsevier BV
DOI: 10.1016/j.molmed.2021.09.007

Individual DNA Methylation Pattern Shifts in Nanoparticles-Exposed Workers Analyzed in Four Consecutive Years

Author(s): Andrea Rossnerova, Katerina Honkova, Irena Chvojkova, Daniela Pelclova, Vladimir Zdimal, Jaroslav A. Hubacek, Lucie Lischkova, Stepanka Vlckova, Jakub Ondracek, Stepanka Dvorackova, Jan Topinka, Pavel Rossner
Published in: International Journal of Molecular Sciences, Issue 22, 2024, Page(s) 7834, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22157834

Long-term hyperglycemia aggravates α-synuclein aggregation and dopaminergic neuronal loss in a Parkinson’s disease mouse model

Author(s): Yi-Qing Lv, Lin Yuan, Yan Sun, Hao-Wen Dou, Ji-Hui Su, Zhi-Pan Hou, Jia-Yi Li, Wen Li
Published in: Translational Neurodegeneration, Issue 11, 2022, ISSN 2047-9158
Publisher: BMC
DOI: 10.1186/s40035-022-00288-z

Plasma and CSF biomarkers in a memory clinic: Head‐to‐head comparison of phosphorylated tau immunoassays

Author(s): Nicholas J. Ashton, Albert Puig‐Pijoan, Marta Milà‐Alomà, Aida Fernández‐Lebrero, Greta García‐Escobar, Fernándo González‐Ortiz, Przemysław R. Kac, Wagner S. Brum, Andréa L. Benedet, Juan Lantero‐Rodriguez, Theresa A. Day, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Gallen Triana‐Baltzer, Setareh Moughadam, Hartmuth Kolb, Paula Ortiz‐Romero, Thomas K. Karikari, Caro
Published in: Alzheimer's & Dementia, Issue 19, 2023, Page(s) 1913-1924, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12841

Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease

Author(s): Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, José Contador, Jordan E. Tanley, Per Selnes, Berglind Gísladóttir, Lene Pålhaugen, Mathilde Suhr Hemminghyth, Jonas Jarholm, Ragnhild Skogseth, Geir Bråthen, Gøril Grøndtvedt, Atle Bjørnerud, Sandra Tecelao, Knut Waterloo, Dag Aarsland, Aida Fernández-Lebrero, Greta García-Escobar, Irene Navalpotro-Gómez, Michael Turton, Agnes Hesthamar,
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-47286-5

Full-length and C-terminal neurogranin in Alzheimer’s disease cerebrospinal fluid analyzed by novel ultrasensitive immunoassays

Author(s): Annika Öhrfelt, Julien Dumurgier, Henrik Zetterberg, Agathe Vrillon, Nicholas J. Ashton, Hlin Kvartsberg, Elodie Bouaziz-Amar, Jacques Hugon, Claire Paquet, Kaj Blennow
Published in: Alzheimer's Research & Therapy, Issue 12, 2021, ISSN 1758-9193
Publisher: BioMed Central
DOI: 10.1186/s13195-020-00748-6

Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids

Author(s): Martin Barak, Veronika Fedorova, Veronika Pospisilova, Jan Raska, Simona Vochyanova, Jiri Sedmik, Hana Hribkova, Hana Klimova, Tereza Vanova, Dasa Bohaciakova
Published in: Stem Cell Reviews and Reports, Issue 18, 2022, Page(s) 792-820, ISSN 2629-3269
Publisher: SPRINGER
DOI: 10.1007/s12015-021-10254-3

Detecting amyloid positivity in early Alzheimer's disease using combinations of plasma Aβ42/Aβ40 and p‐tau

Author(s): Shorena Janelidze, Sebastian Palmqvist, Antoine Leuzy, Erik Stomrud, Inge M.W. Verberk, Henrik Zetterberg, Nicholas J. Ashton, Pedro Pesini, Leticia Sarasa, José Antonio Allué, Charlotte E. Teunissen, Jeffrey L. Dage, Kaj Blennow, Niklas Mattsson‐Carlgren, Oskar Hansson
Published in: Alzheimer's & Dementia, Issue 18, 2023, Page(s) 283-293, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.12395

Pathway-specific polygenic scores for Alzheimer’s disease are associated with changes in brain structure in younger and older adults

Author(s): Judith R Harrison, Sonya F Foley, Emily Baker, Matthew Bracher-Smith, Peter Holmans, Evie Stergiakouli, David E J Linden, Xavier Caseras, Derek K Jones, Valentina Escott-Price
Published in: Brain Communications, Issue 5, 2024, ISSN 2632-1297
Publisher: OXFORD UNIVERSITY PRESS
DOI: 10.1093/braincomms/fcad229

Prospects for gene replacement therapies in amyotrophic lateral sclerosis

Author(s): Ilaria Giovannelli, Adrian Higginbottom, Janine Kirby, Mimoun Azzouz, Pamela J. Shaw
Published in: Nature Reviews Neurology, Issue 19, 2023, Page(s) 39-52, ISSN 1759-4758
Publisher: Nature Publishing Group
DOI: 10.1038/s41582-022-00751-5

Identification of single nucleotide variants in the Moroccan population by whole-genome sequencing

Author(s): Lucy Crooks, Johnathan Cooper-Knock, Paul R. Heath, Ahmed Bouhouche, Mostafa Elfahime, Mimoun Azzouz, Youssef Bakri, Mohammed Adnaoui, Azeddine Ibrahimi, Saaïd Amzazi, Rachid Tazi-Ahnini
Published in: BMC Genetics, Issue 21, 2021, ISSN 1471-2156
Publisher: BioMed Central
DOI: 10.1186/s12863-020-00917-4

Epilepsy and epileptiform activity in late-onset Alzheimer disease: clinical and pathophysiological advances, gaps and conundrums

Author(s): Anita Kamondi, Madeleine Grigg-Damberger, Wolfgang Löscher, Heikki Tanila, Andras Attila Horvath
Published in: Nature Reviews Neurology, Issue 20, 2024, Page(s) 162-182, ISSN 1759-4758
Publisher: Nature Publishing Group
DOI: 10.1038/s41582-024-00932-4

Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease

Author(s): Shorena Janelidze, Charlotte E. Teunissen, Henrik Zetterberg, José Antonio Allué, Leticia Sarasa, Udo Eichenlaub, Tobias Bittner, Vitaliy Ovod, Inge M. W. Verberk, Kenji Toba, Akinori Nakamura, Randall J. Bateman, Kaj Blennow, Oskar Hansson
Published in: JAMA Neurology, Issue 78, 2023, Page(s) 1375, ISSN 2168-6149
Publisher: American Medical Association
DOI: 10.1001/jamaneurol.2021.3180

The Impact of Music on Stress Biomarkers: Protocol of a Substudy of the Cluster-Randomized Controlled Trial Music Interventions for Dementia and Depression in ELderly Care (MIDDEL)

Author(s): Naomi L. Rasing, Sarah I. M. Janus, Gunter Kreutz, Vigdis Sveinsdottir, Christian Gold, Urs M. Nater, Sytse U. Zuidema
Published in: Brain Sciences, Issue 12, 2024, Page(s) 485, ISSN 2076-3425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/brainsci12040485

Reporter-Based Screens for the Ubiquitin/Proteasome System

Author(s): Maria E. Gierisch, Tatiana A. Giovannucci, Nico P. Dantuma
Published in: Frontiers in Chemistry, Issue 8, 2020, ISSN 2296-2646
Publisher: FRONTIERS MEDIA SA
DOI: 10.3389/fchem.2020.00064

The SORL1 p.Y1816C variant causes impaired endosomal dimerization and autosomal dominant Alzheimer’s disease

Author(s): Anne Mette G. Jensen, Jan Raska, Petr Fojtik, Giulia Monti, Melanie Lunding, Simona Bartova, Veronika Pospisilova, Sven J. van der Lee, Jasper Van Dongen, Liene Bossaerts, Christine Van Broeckhoven, Oriol Dols-Icardo, Alberto Lléo, Sonia Bellini, Roberta Ghidoni, Marc Hulsman, Gregory A. Petsko, Kristel Sleegers, Dasa Bohaciakova, Henne Holstege, Olav M. Andersen
Published in: Proceedings of the National Academy of Sciences, Issue 121, 2024, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2408262121

Language impairment in the genetic forms of behavioural variant frontotemporal dementia

Author(s): Kiran Samra, Amy M. MacDougall, Arabella Bouzigues, Martina Bocchetta, David M. Cash, Caroline V. Greaves, Rhian S. Convery, John C. van Swieten, Harro Seelaar, Lize Jiskoot, Fermin Moreno, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B. Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe, Alexandre
Published in: Journal of Neurology, Issue 270, 2023, Page(s) 1976-1988, ISSN 0340-5354
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-022-11512-1

Pre-clinical development of AP4B1 gene replacement therapy for hereditary spastic paraplegia type 47

Author(s): Jessica P Wiseman, Joseph M Scarrott, João Alves-Cruzeiro, Afshin Saffari, Cedric Böger, Evangelia Karyka, Emily Dawes, Alexandra K Davies, Paolo M Marchi, Emily Graves, Fiona Fernandes, Zih-Liang Yang, Ian Coldicott, Jennifer Hirst, Christopher P Webster, J Robin Highley, Neil Hackett, Adrienn Angyal, Thushan de Silva, Adrian Higginbottom, Pamela J Shaw, Laura Ferraiuolo, Darius Ebrahimi-Fakhar
Published in: EMBO Molecular Medicine, Issue 16, 2024, Page(s) 2882-2917, ISSN 1757-4684
Publisher: EMBO PRESS, GERMANY
DOI: 10.1038/s44321-024-00148-5

Blood‐brain barrier dysfunction and reduced cerebrospinal fluid levels of soluble amyloid precursor protein‐β in patients with subcortical small‐vessel disease

Author(s): Petronella Kettunen, Maria Bjerke, Carl Eckerström, Michael Jonsson, Henrik Zetterberg, Kaj Blennow, Johan Svensson, Anders Wallin
Published in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Issue 14, 2023, ISSN 2352-8729
Publisher: WILEY
DOI: 10.1002/dad2.12296

Demographic and clinical profile of residents living with dementia and depressive symptoms in Australian private residential aged care: Data from the Music Interventions for Dementia and Depression in ELderly care (<scp>MIDDEL</scp>) cluster‐randomised controlled trial

Author(s): Young‐Eun C. Lee, Tanara Vieira Sousa, Phoebe A. Stretton‐Smith, Christian Gold, Monika Geretsegger, Felicity A. Baker
Published in: Australasian Journal on Ageing, Issue 41, 2023, ISSN 1440-6381
Publisher: Council on Ageing
DOI: 10.1111/ajag.13104

Molecular Mechanisms of Amyloid-β Self-Assembly Seeded by In Vivo-Derived Fibrils and Inhibitory Effects of the BRICHOS Chaperone

Author(s): Rakesh Kumar, Luis Enrique Arroyo-García, Shaffi Manchanda, Laurène Adam, Giusy Pizzirusso, Henrik Biverstål, Per Nilsson, André Fisahn, Jan Johansson, Axel Abelein
Published in: ACS Chemical Neuroscience, 2023, ISSN 1948-7193
Publisher: American Chemical Society
DOI: 10.1021/acschemneuro.3c00044

Primary progressive aphasia: ReADing the clinical GRANularity

Author(s): Anthipa Chokesuwattanaskul, Charles R Marshall, Natasja van Harskamp, Henry Houlden, Jonathan D Rohrer, Chris JD Hardy, Jason D Warren
Published in: Practical Neurology, Issue 22, 2023, Page(s) 509-514, ISSN 1474-7758
Publisher: Blackwell Publishing Inc.
DOI: 10.1136/practneurol-2022-003460

Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies

Author(s): Ilaria Poggiolini, Vandana Gupta, Michael Lawton, Seoyun Lee, Aadil El-Turabi, Agustin Querejeta-Coma, Claudia Trenkwalder, Friederike Sixel-Döring, Alexandra Foubert-Samier, Anne Pavy-Le Traon, Giuseppe Plazzi, Francesco Biscarini, Jacques Montplaisir, Jean-François Gagnon, Ronald B Postuma, Elena Antelmi, Wassilios G Meissner, Brit Mollenhauer, Yoav Ben-Shlomo, Michele T Hu, Laura Parkkinen
Published in: Brain, Issue 145, 2022, Page(s) 584-595, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awab431

Cognitive and brain development is independently influenced by socioeconomic status and polygenic scores for educational attainment

Author(s): Nicholas Judd, Bruno Sauce, John Wiedenhoeft, Jeshua Tromp, Bader Chaarani, Alexander Schliep, Betteke van Noort, Jani Penttilä, Yvonne Grimmer, Corinna Insensee, Andreas Becker, Tobias Banaschewski, Arun L. W. Bokde, Erin Burke Quinlan, Sylvane Desrivières, Herta Flor, Antoine Grigis, Penny Gowland, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges,
Published in: Proceedings of the National Academy of Sciences, Issue 117, 2022, Page(s) 12411-12418, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2001228117

TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration

Author(s): Kaspar Russ, Gabriel Teku, Luc Bousset, Virginie Redeker, Sara Piel, Ekaterina Savchenko, Yuriy Pomeshchik, Jimmy Savistchenko, Tina C. Stummann, Carla Azevedo, Anna Collin, Stefano Goldwurm, Karina Fog, Eskil Elmer, Mauno Vihinen, Ronald Melki, Laurent Roybon
Published in: Cell Reports, Issue 34, 2021, Page(s) 108895, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2021.108895

Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected

Author(s): Marc Suárez‐Calvet, Thomas K Karikari, Nicholas J Ashton, Juan Lantero Rodríguez, Marta Milà‐Alomà, Juan Domingo Gispert, Gemma Salvadó, Carolina Minguillon, Karine Fauria, Mahnaz Shekari, Oriol Grau‐Rivera, Eider M Arenaza‐Urquijo, Aleix Sala‐Vila, Gonzalo Sánchez‐Benavides, José Maria González‐de‐Echávarri, Gwendlyn Kollmorgen, Erik Stoops, Eugeen Vanmechelen, Henrik Zet
Published in: EMBO Molecular Medicine, Issue 12, 2023, ISSN 1757-4676
Publisher: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202012921

Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

Author(s): Itziar de Rojas, Sonia Moreno-Grau, Niccolo Tesi, Benjamin Grenier-Boley, Victor Andrade, Iris E. Jansen, Nancy L. Pedersen, Najada Stringa, Anna Zettergren, Isabel Hernández, Laura Montrreal, Carmen Antúnez, Anna Antonell, Rick M. Tankard, Joshua C. Bis, Rebecca Sims, Céline Bellenguez, Inés Quintela, Antonio González-Perez, Miguel Calero, Emilio Franco-Macías, Juan Macías, Rafael Blesa, L
Published in: Nature Communications, Issue 12, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22491-8

Signs of neuroaxonal injury in preeclampsia—A case control study

Author(s): Malin Andersson, Jonatan Oras, Sven Egron Thörn, Ove Karlsson, Peter Kälebo, Henrik Zetterberg, Kaj Blennow, Lina Bergman
Published in: PLOS ONE, Issue 16, 2024, Page(s) e0246786, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0246786

Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads

Author(s): Gemma Salvadó, Rik Ossenkoppele, Nicholas J Ashton, Thomas G Beach, Geidy E Serrano, Eric M Reiman, Henrik Zetterberg, Niklas Mattsson‐Carlgren, Shorena Janelidze, Kaj Blennow, Oskar Hansson
Published in: EMBO Molecular Medicine, Issue 15, 2023, ISSN 1757-4676
Publisher: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202217123

Predicting Alzheimer's disease progression: Results from the TADPOLE Challenge

Author(s): Razvan V. Marinescu, Esther E. Bron, Neil P. Oxtoby, Alexandra L. Young, Arthur W. Toga, Michael W. Weiner, Frederik Barkhof, Nick C. Fox, Polina Golland, Stefan Klein, Daniel C. Alexander
Published in: Alzheimer's & Dementia, Issue 16, 2023, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.039538

Polygenic risk scores for Alzheimer's disease are related to dementia risk in APOE ɛ4 negatives

Author(s): Jenna Najar, Sven J. van der Lee, Erik Joas, Hanna Wetterberg, John Hardy, Rita Guerreiro, Jose Bras, Margda Waern, Silke Kern, Henrik Zetterberg, Kaj Blennow, Ingmar Skoog, Anna Zettergren
Published in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Issue 13, 2023, ISSN 2352-8729
Publisher: WILEY
DOI: 10.1002/dad2.12142

The architecture of abnormal reward behaviour in dementia: multimodal hedonic phenotypes and brain substrate

Author(s): Anthipa Chokesuwattanaskul, Harmony Jiang, Rebecca L Bond, Daniel A Jimenez, Lucy L Russell, Harri Sivasathiaseelan, Jeremy C S Johnson, Elia Benhamou, Jennifer L Agustus, Janneke E P van Leeuwen, Peerapat Chokesuwattanaskul, Chris J D Hardy, Charles R Marshall, Jonathan D Rohrer, Jason D Warren
Published in: Brain Communications, Issue 5, 2023, ISSN 2632-1297
Publisher: OXFORD UNIVERSITY PRESS
DOI: 10.1093/braincomms/fcad027

Longitudinal Cognitive Changes in Genetic Frontotemporal Dementia Within the GENFI Cohort

Author(s): Jackie M. Poos, Amy MacDougall, Esther van den Berg, Lize C. Jiskoot, Janne M. Papma, Emma L. van der Ende, Harro Seelaar, Lucy L. Russell, Georgia Peakman, Rhian Convery, Yolande A.L. Pijnenburg, Fermin Moreno, Raquel Sanchez-Valle, Barbara Borroni, Robert Laforce, Marie-Claire Doré, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Daniela Galimberti, James B. Rowe, Elizabeth Finger, Mat
Published in: Neurology, Issue 99, 2024, ISSN 0028-3878
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000200384

Accurate Bayesian segmentation of thalamic nuclei using diffusion MRI and an improved histological atlas

Author(s): Henry F.J. Tregidgo, Sonja Soskic, Juri Althonayan, Chiara Maffei, Koen Van Leemput, Polina Golland, Ricardo Insausti, Garikoitz Lerma-Usabiaga, César Caballero-Gaudes, Pedro M. Paz-Alonso, Anastasia Yendiki, Daniel C. Alexander, Martina Bocchetta, Jonathan D. Rohrer, Juan Eugenio Iglesias
Published in: NeuroImage, Issue 274, 2024, Page(s) 120129, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2023.120129

Associations between misfolded alpha‐synuclein aggregates and Alzheimer's disease pathology in vivo

Author(s): Alexa Pichet Binette, Angela Mammana, Laura Wisse, Marcello Rossi, Olof Strandberg, Ruben Smith, Niklas Mattsson‐Carlgren, Shorena Janelidze, Sebastian Palmqvist, null null, Alice Ticca, Erik Stomrud, Piero Parchi, Oskar Hansson
Published in: Alzheimer's & Dementia, Issue 20, 2024, Page(s) 7624-7634, ISSN 1552-5260
Publisher: Elsevier BV
DOI: 10.1002/alz.14225

Cardiovascular health metrics from mid- to late-life and risk of dementia: A population-based cohort study in Finland

Author(s): Yajun Liang, Tiia Ngandu, Tiina Laatikainen, Hilkka Soininen, Jaakko Tuomilehto, Miia Kivipelto, Chengxuan Qiu
Published in: PLOS Medicine, Issue 17, 2020, Page(s) e1003474, ISSN 1549-1676
Publisher: PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pmed.1003474

Creating the Pick’s disease International Consortium: Association study ofMAPTH2 haplotype with risk of Pick’s disease

Author(s): Rebecca R Valentino, William J Scotton, Shanu F Roemer, Tammaryn Lashley, Michael G Heckman, Maryam Shoai, Alejandro Martinez-Carrasco, Nicole Tamvaka, Ronald L Walton, Matthew C Baker, Hannah L Macpherson, Raquel Real, Alexandra I Soto-Beasley, Kin Mok, Tamas Revesz, Thomas T Warner, Zane Jaunmuktane, Bradley F Boeve, Elizabeth A Christopher, Michael DeTure, Ranjan Duara, Neill R Graff-Radford, K
Published in: MEDRXIV THE PREPRINT SERVER FOR HEALTH SCIENCES, 2023
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.04.17.23288471

Symptom-led staging for primary progressive aphasia

Author(s): Chris JD Hardy, Cathleen Taylor-Rubin, Beatrice Taylor, Emma Harding, Aida Suarez Gonzalez, Jessica Jiang, Laura Thompson, Rachel Kingma, Anthipa Chokesuwattanaskul, Ffion Walker, Suzie Barker, Emilie Brotherhood, Claire Waddington, Olivia Wood, Nikki Zimmermann, Nuriye Kupeli, Keir XX Yong, Paul M Camic, Josh Stott, Charles R Marshall, Neil P. Oxtoby, Jonathan D Rohrer, Anna Volkmer, Sebastian J
Published in: MEDRXIV THE PREPRINT SERVER FOR HEALTH SCIENCES, 2023
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.03.13.23286972

Differential Impairment of Cerebrospinal Fluid Synaptic Biomarkers in the Genetic Forms of Frontotemporal Dementia

Author(s): Aitana Sogorb-Esteve, Johanna Nilsson, Imogen J Swift, Carolin Heller, Lucy L Russell, Georgia Peakman, Rhian S Convery, John C van Swieten, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Raquel Sánchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Rik Vanderberghe, Elisabeth Finger, Fabrizio Tagliavini, Isabel
Published in: RESEARCH SQUARE PREPRINTS, 2022
Publisher: Research Square Platform LLC, SPRINGER NATURE
DOI: 10.21203/rs.3.rs-1188941/v1

Leveraging long-term smartwatch data to inform Parkinson’s disease progression, subtypes, and risk

Author(s): Ann-Kathrin Schalkamp, Kathryn J Peall, Neil A Harrison, Valentina Escott-Price, Cynthia Sandor
Published in: MEDRXIV THE PREPRINT SERVER FOR HEALTH SCIENCES, 2023
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.09.13.23295404

Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementia

Author(s): Aurélie Bussy, Jake Levy, Tristin Best, Raihaan Patel, Lani Cupo, Tim Van Langenhove, Jorgen Nielsen, Yolande Pijnenburg, Maria Landqvist Waldö, Anne Remes, Matthias L Schroeter, Isabel Santana, Florence Pasquier, Markus Otto, Adrian Danek, Johannes Levin, Isabelle Le Ber, Rik Vandenberghe, Matthis Synofzik, Fermin Moreno, Alexandre de Mendonça, Raquel Sanchez-Valle, Robert Laforce, Tobias Lang
Published in: BIORXIV THE PREPRINT SERVER FOR BIOLOGY, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.11.12.468429

Revealing nervous and cardiac system interactions by iPSC-Based platforms

Author(s): Ozlem Mutlu Burnaz, Esra Cagavi
Published in: iPSCs - State of the Science, Issue Volume 16, 2022, Page(s) 1-28
Publisher: Elsevier
DOI: 10.1016/b978-0-323-85767-3.00002-5

Domain-Agnostic Segmentation of Thalamic Nuclei from Joint Structural and Diffusion MRI

Author(s): Henry F. J. Tregidgo, Sonja Soskic, Mark D. Olchanyi, Juri Althonayan, Benjamin Billot, Chiara Maffei, Polina Golland, Anastasia Yendiki, Daniel C. Alexander, Martina Bocchetta, Jonathan D. Rohrer, Juan Eugenio Iglesias
Published in: Lecture Notes in Computer Science, Medical Image Computing and Computer Assisted Intervention – MICCAI 2023, 2024, Page(s) 247-257
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-43993-3_24

The Emerging Role of AI in Dementia Research and Healthcare

Author(s): Janice M. Ranson, Magda Bucholc, Donald Lyall, Danielle Newby, Laura Winchester, Neil Oxtoby, Michele Veldsman, Timothy Rittman, Sarah Marzi, Nathan Skene, Ahmad Al Khleifat, Isabelle Foote, Vasiliki Orgeta, Andrey Kormilitzin, David J. Llewellyn
Published in: Brain Informatics and Health, Artificial Intelligence in Healthcare, 2024, Page(s) 95-106
Publisher: Springer Nature Singapore
DOI: 10.1007/978-981-19-5272-2_4

Searching for OpenAIRE data...

Deliverables

Publications

Share this page Share this page on social networks

Download Download the content of the page