ERA-NET to support the Joint Programming in Neurodegenerative Diseases strategic plan (JPND)

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Joint selection list of the projects to be funded

Procedures for public consultations on the JPND website

Call text and call documents

Web story, Supported project Fact Sheets, Interviews

Informal Interviews

Electronic submission tool

JPND website sections, including call-related information

Pubblicazioni

Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans

Autori: Marco Sazzini, Paolo Abondio, Stefania Sarno, Guido Alberto Gnecchi-Ruscone, Matteo Ragno, Cristina Giuliani, Sara De Fanti, Claudia Ojeda-Granados, Alessio Boattini, Julien Marquis, Armand Valsesia, Jerome Carayol, Frederic Raymond, Chiara Pirazzini, Elena Marasco, Alberto Ferrarini, Luciano Xumerle, Sebastiano Collino, Daniela Mari, Beatrice Arosio, Daniela Monti, Giuseppe Passarino, Patrizia D
Pubblicato in: BMC Biology, Numero 18, 2021, ISSN 1741-7007
Editore: BioMed Central
DOI: 10.1186/s12915-020-00778-4

Plasma phosphorylated tau181 and neurodegeneration in Alzheimer’s disease

Autori: Oskar Hansson, Nicholas Cullen, Henrik Zetterberg, null null, Kaj Blennow, Niklas Mattsson‐Carlgren
Pubblicato in: Annals of Clinical and Translational Neurology, Numero 8, 2023, Pagina/e 259-265, ISSN 2328-9503
Editore: WILEY
DOI: 10.1002/acn3.51253

The Role of Brain Integrity in the Association between Occupational Complexity and Cognitive Performance in Subjects with Increased Risk of Dementia

Autori: Anders Rydström, Ruth Stephen, Ingemar Kåreholt, Alexander Darin Mattsson, Tiia Ngandu, Jenni Lehtisalo, Lars Bäckman, Nina Kemppainen, Juha Rinne, Shireen Sindi, Hilkka Soininen, Ritva Vanninen, Alina Solomon, Francesca Mangialasche
Pubblicato in: Gerontology, Numero 69, 2024, Pagina/e 972-985, ISSN 0304-324X
Editore: S. Karger AG
DOI: 10.1159/000530688

Neurofilament light levels predict clinical progression and death in multiple system atrophy

Autori: Viorica Chelban, Elham Nikram, Alexandra Perez-Soriano, Carlo Wilke, Alexandra Foubert-Samier, Nirosen Vijiaratnam, Tong Guo, Edwin Jabbari, Simisola Olufodun, Mariel Gonzalez, Konstantin Senkevich, Brice Laurens, Patrice Péran, Olivier Rascol, Anne Pavy Le Traon, Emily G Todd, Alyssa A Costantini, Sondos Alikhwan, Ambreen Tariq, Bai Lin Ng, Esteban Muñoz, Celia Painous, Yaroslau Compta, Carme J
Pubblicato in: Brain, Numero 145, 2024, Pagina/e 4398-4408, ISSN 0006-8950
Editore: Oxford University Press
DOI: 10.1093/brain/awac253

Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms

Autori: Arvid Edén, Anna Grahn, Daniel Bremell, Anahit Aghvanyan, Pradeepthi Bathala, Dietmar Fuchs, Johanna Gostner, Lars Hagberg, Nelly Kanberg, Sunsanee Kanjananimmanont, Magnus Lindh, Salvia Misaghian, Staffan Nilsson, Michael Schöll, George Sigal, Erika Stentoft, Marie Studahl, Aylin Yilmaz, Mingyue Wang, Martin Stengelin, Henrik Zetterberg, Magnus Gisslén
Pubblicato in: JAMA Network Open, Numero 5, 2024, Pagina/e e2213253, ISSN 2574-3805
Editore: AMER MEDICAL ASSOC
DOI: 10.1001/jamanetworkopen.2022.13253

Association between polygenic risk score of Alzheimer’s disease and plasma phosphorylated tau in individuals from the Alzheimer’s Disease Neuroimaging Initiative

Autori: null null, Anna Zettergren, Jodie Lord, Nicholas J. Ashton, Andrea L. Benedet, Thomas K. Karikari, Juan Lantero Rodriguez, Anniina Snellman, Marc Suárez-Calvet, Petroula Proitsi, Henrik Zetterberg, Kaj Blennow
Pubblicato in: Alzheimer's Research & Therapy, Numero 13, 2021, ISSN 1758-9193
Editore: BioMed Central
DOI: 10.1186/s13195-020-00754-8

Diagnostic Performance of Cerebrospinal Fluid Neurofilament Light Chain and Soluble Amyloid-β Protein Precursor β in the Subcortical Small Vessel Type of Dementia

Autori: Elin Axelsson Andrén, Petronella Kettunen, Maria Bjerke, Sindre Rolstad, Henrik Zetterberg, Kaj Blennow, Anders Wallin, Johan Svensson
Pubblicato in: Journal of Alzheimer's Disease, Numero 96, 2024, Pagina/e 1515-1528, ISSN 1387-2877
Editore: IOS Press
DOI: 10.3233/jad-230680

Neuroinflammation in Alzheimer disease

Autori: Michael T. Heneka, Wiesje M. van der Flier, Frank Jessen, Jeroen Hoozemanns, Dietmar Rudolf Thal, Delphine Boche, Frederic Brosseron, Charlotte Teunissen, Henrik Zetterberg, Andreas H. Jacobs, Paul Edison, Alfredo Ramirez, Carlos Cruchaga, Jean-Charles Lambert, Agustin Ruiz Laza, Jose Vicente Sanchez-Mut, Andre Fischer, Sergio Castro-Gomez, Thor D. Stein, Luca Kleineidam, Michael Wagner, Jonas J.
Pubblicato in: Nature Reviews Immunology, 2024, ISSN 1474-1733
Editore: Nature Publishing Group
DOI: 10.1038/s41577-024-01104-7

Exploring CSF neurofilament light as a biomarker for MS in clinical practice; a retrospective registry-based study

Autori: Igal Rosenstein, Markus Axelsson, Lenka Novakova, Kaj Blennow, Henrik Zetterberg, Jan Lycke
Pubblicato in: Multiple Sclerosis Journal, Numero 28, 2025, Pagina/e 872-884, ISSN 1352-4585
Editore: SAGE Publications
DOI: 10.1177/13524585211039104

Establishment of reference values for plasma neurofilament light based on healthy individuals aged 5–90 years

Autori: Joel Simrén, Ulf Andreasson, Johan Gobom, Marc Suarez Calvet, Barbara Borroni, Christopher Gillberg, Lars Nyberg, Roberta Ghidoni, Elisabeth Fernell, Mats Johnson, Herman Depypere, Caroline Hansson, Ingibjörg H Jonsdottir, Henrik Zetterberg, Kaj Blennow
Pubblicato in: Brain Communications, Numero 4, 2022, ISSN 2632-1297
Editore: OXFORD UNIV PRESS
DOI: 10.1093/braincomms/fcac174

Social Health and Cognitive Change in Old Age: Role of Brain Reserve

Autori: Anna Marseglia, Grégoria Kalpouzos, Erika J. Laukka, Jane Maddock, Praveetha Patalay, Hui‐Xin Wang, Lars Bäckman, Eric Westman, Anna‐Karin Welmer, Serhiy Dekhtyar, null null
Pubblicato in: Annals of Neurology, Numero 93, 2024, Pagina/e 844-855, ISSN 0364-5134
Editore: John Wiley & Sons Inc.
DOI: 10.1002/ana.26591

Hospital-treated infections in early- and mid-life and risk of Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis: A nationwide nested case-control study in Sweden

Autori: Jiangwei Sun, Jonas F. Ludvigsson, Caroline Ingre, Fredrik Piehl, Karin Wirdefeldt, Ulrika Zagai, Weimin Ye, Fang Fang
Pubblicato in: PLOS Medicine, Numero 19, 2023, Pagina/e e1004092, ISSN 1549-1676
Editore: PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pmed.1004092

CSF biomarkers in patients with epilepsy in Alzheimer’s disease: a nation-wide study

Autori: Rakesh Kumar Banote, Samuel Håkansson, Henrik Zetterberg, Johan Zelano
Pubblicato in: Brain Communications, Numero 4, 2022, ISSN 2632-1297
Editore: OXFORD UNIV PRESS
DOI: 10.1093/braincomms/fcac210

Pitfalls of predicting age‐related traits by polygenic risk scores

Autori: Valentina Escott‐Price, Karl Michael Schmidt
Pubblicato in: Annals of Human Genetics, Numero 87, 2023, Pagina/e 203-209, ISSN 0003-4800
Editore: Blackwell Publishing Inc.
DOI: 10.1111/ahg.12520

Anomia is present pre-symptomatically in frontotemporal dementia due to MAPT mutations

Autori: Arabella Bouzigues, Lucy L. Russell, Georgia Peakman, Martina Bocchetta, Caroline V. Greaves, Rhian S. Convery, Emily Todd, James B. Rowe, Barbara Borroni, Daniela Galimberti, Pietro Tiraboschi, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Finger, John C. van Swieten, Harro Seelaar, Lize Jiskoot, Sandro Sorbi, Chris R. Butler, Caroline Graff, Alexander Gerhard, Tobias Langheinrich, Robert La
Pubblicato in: Journal of Neurology, Numero 269, 2022, Pagina/e 4322-4332, ISSN 0340-5354
Editore: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-022-11068-0

Human Small Heat Shock Protein B8 Inhibits Protein Aggregation without Affecting the Native Folding Process

Autori: Dhawal Choudhary, Laura Mediani, Mario J. Avellaneda, Sveinn Bjarnason, Simon Alberti, Edgar E. Boczek, Pétur O. Heidarsson, Alessandro Mossa, Serena Carra, Sander J. Tans, Ciro Cecconi
Pubblicato in: Journal of the American Chemical Society, Numero 145, 2023, Pagina/e 15188-15196, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.3c02022

No increase of serum neurofilament light in relapsing-remitting multiple sclerosis patients switching from standard to extended-interval dosing of natalizumab

Autori: Magnus Johnsson, Helen H Farman, Kaj Blennow, Henrik Zetterberg, Clas Malmeström, Markus Axelsson, Jan Lycke
Pubblicato in: Multiple Sclerosis Journal, Numero 28, 2025, Pagina/e 2070-2080, ISSN 1352-4585
Editore: SAGE Publications
DOI: 10.1177/13524585221108080

Role of Alkali Cations in DNA–Thioflavin T Interaction

Autori: P. Hanczyc
Pubblicato in: The Journal of Physical Chemistry B, Numero 128, 2024, Pagina/e 7520-7529, ISSN 1520-6106
Editore: American Chemical Society
DOI: 10.1021/acs.jpcb.4c02417

Infections among individuals with multiple sclerosis, Alzheimer’s disease and Parkinson’s disease

Autori: Yihan Hu, Kejia Hu, Huan Song, Yudi Pawitan, Fredrik Piehl, Fang Fang
Pubblicato in: Brain Communications, Numero 5, 2023, ISSN 2632-1297
Editore: OXFORD UNIV PRESS
DOI: 10.1093/braincomms/fcad065

Developing consensus description of group music therapy characteristics for persons with dementia

Autori: Sarah I. M. Janus, Annemieke C. Vink, Hanne Mette Ridder, Monika Geretsegger, Brynjulf Stige, Christian Gold, Sytse U. Zuidema
Pubblicato in: Nordic Journal of Music Therapy, Numero 30, 2021, Pagina/e 24-40, ISSN 0809-8131
Editore: Sogn and Fjordane University College
DOI: 10.1080/08098131.2020.1779790

C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons

Autori: Paolo M Marchi, Lara Marrone, Laurent Brasseur, Audrey Coens, Christopher P Webster, Luc Bousset, Marco Destro, Emma F Smith, Christa G Walther, Victor Alfred, Raffaele Marroccella, Emily J Graves, Darren Robinson, Allan C Shaw, Lai Mei Wan, Andrew J Grierson, Stephen J Ebbens, Kurt J De Vos, Guillaume M Hautbergue, Laura Ferraiuolo, Ronald Melki, Mimoun Azzouz
Pubblicato in: Life Science Alliance, Numero 5, 2024, Pagina/e e202101276, ISSN 2575-1077
Editore: The Rockefeller University Press, NEW YORK
DOI: 10.26508/lsa.202101276

Ten years of image analysis and machine learning competitions in dementia

Autori: Esther E. Bron, Stefan Klein, Annika Reinke, Janne M. Papma, Lena Maier-Hein, Daniel C. Alexander, Neil P. Oxtoby
Pubblicato in: NeuroImage, Numero 253, 2024, Pagina/e 119083, ISSN 1053-8119
Editore: Academic Press
DOI: 10.1016/j.neuroimage.2022.119083

Multimodal Preventive Trial for Alzheimer's Disease: MIND-ADmini Pilot Trial Study Design and Progress

Autori: S. Sindi, C. Thunborg, A. Rosenberg, P. Andersen, S. Andrieu, L.M. Broersen, N. Coley, C. Couderc, C.Z. Duval, G. Faxen-Irving, G. Hagman, M. Hallikainen, K. Håkansson, J. Lehtisalo, N. Levak, F. Mangialasche, J. Pantel, E. Kekkonen, A. Rydström, A. Stigsdotter-Neely, A. Wimo, T. Ngandu, H. Soininen, T. Hartmann, A. Solomon, Miia Kivipelto
Pubblicato in: The Journal of Prevention of Alzheimer's Disease, Numero 9, 2025, Pagina/e 30-39, ISSN 2274-5807
Editore: SPRINGER BASEL AG
DOI: 10.14283/jpad.2022.4

A genome-wide association study of plasma phosphorylated tau181

Autori: Jodie Lord, Anna Zettergren, Nicholas J. Ashton, Thomas K. Karikari, Andrea L. Benedet, Joel Simrén, Abdul Hye, Dag Aarsland, Kaj Blennow, Henrik Zetterberg, Petroula Proitsi
Pubblicato in: Neurobiology of Aging, Numero 106, 2022, Pagina/e 304.e1-304.e3, ISSN 0197-4580
Editore: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2021.04.018

Comprehensive short and long read sequencing analysis for the Gaucher and Parkinson’s disease-associated GBA gene

Autori: Marco Toffoli, Xiao Chen, Fritz J. Sedlazeck, Chiao-Yin Lee, Stephen Mullin, Abigail Higgins, Sofia Koletsi, Monica Emili Garcia-Segura, Esther Sammler, Sonja W. Scholz, Anthony H. V. Schapira, Michael A. Eberle, Christos Proukakis
Pubblicato in: Communications Biology, Numero 5, 2022, ISSN 2399-3642
Editore: SPRINGER NATURE
DOI: 10.1038/s42003-022-03610-7

Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer’s Disease: A Randomized Controlled Trial—The OmegAD Study

Autori: Avin Tofiq, Henrik Zetterberg, Kaj Blennow, Hans Basun, Tommy Cederholm, Maria Eriksdotter, Gerd Faxén-Irving, Erik Hjorth, Fredrik Jernerén, Marianne Schultzberg, Lars-Olof Wahlund, Jan Palmblad, Yvonne Freund-Levi
Pubblicato in: Journal of Alzheimer's Disease, Numero 83, 2024, Pagina/e 1291-1301, ISSN 1387-2877
Editore: IOS Press
DOI: 10.3233/jad-210007

Circulating Brain-Injury Markers After Surgery for Craniosynostosis

Autori: Isak Michaëlsson, Thomas Skoglund, Tobias Hallén, Robert Olsson, Giovanni Maltese, Peter Tarnow, Madiha Bhatti-Søfteland, Henrik Zetterberg, Kaj Blennow, Lars Kölby
Pubblicato in: World Neurosurgery, Numero 173, 2024, Pagina/e e593-e599, ISSN 1878-8750
Editore: Elsevier BV
DOI: 10.1016/j.wneu.2023.02.102

Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain

Autori: Rakesh Kumar, Tanguy Le Marchand, Laurène Adam, Raitis Bobrovs, Gefei Chen, Jēkabs Fridmanis, Nina Kronqvist, Henrik Biverstål, Kristaps Jaudzems, Jan Johansson, Guido Pintacuda, Axel Abelein
Pubblicato in: Nature Communications, Numero 15, 2024, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-024-45192-4

Association of Serum Brain-Derived Tau With Clinical Outcome and Longitudinal Change in Patients With Severe Traumatic Brain Injury

Autori: Fernando Gonzalez-Ortiz, Maciej Dulewicz, Nicholas J. Ashton, Przemysław R. Kac, Henrik Zetterberg, Emma Andersson, Yara Yakoub, Jörg Hanrieder, Michael Turton, Peter Harrison, Bengt Nellgård, Thomas K. Karikari, Kaj Blennow
Pubblicato in: JAMA Network Open, Numero 6, 2023, Pagina/e e2321554, ISSN 2574-3805
Editore: AMER MEDICAL ASSOC
DOI: 10.1001/jamanetworkopen.2023.21554

Plasma and CSF NfL are differentially associated with biomarker evidence of neurodegeneration in a community‐based sample of 70‐year‐olds

Autori: Anna Dittrich, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Joel Simrén, Fiona Geiger, Anna Zettergren, Sara Shams, Alejandra Machado, Eric Westman, Michael Schöll, Ingmar Skoog, Silke Kern
Pubblicato in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Numero 14, 2023, ISSN 2352-8729
Editore: WILEY
DOI: 10.1002/dad2.12295

Dementia prevention in memory clinics: recommendations from the European task force for brain health services

Autori: Giovanni B. Frisoni, Daniele Altomare, Federica Ribaldi, Nicolas Villain, Carol Brayne, Naaheed Mukadam, Marc Abramowicz, Frederik Barkhof, Marcelo Berthier, Melanie Bieler-Aeschlimann, Kaj Blennow, Andrea Brioschi Guevara, Emmanuel Carrera, Gaël Chételat, Chantal Csajka, Jean-François Demonet, Alessandra Dodich, Valentina Garibotto, Jean Georges, Samia Hurst, Frank Jessen, Miia Kivipelto, Davi
Pubblicato in: The Lancet Regional Health - Europe, Numero 26, 2023, Pagina/e 100576, ISSN 2666-7762
Editore: The Lancet Regional Health - Europe
DOI: 10.1016/j.lanepe.2022.100576

Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development

Autori: Tereza Vanova, Jiri Sedmik, Jan Raska, Katerina Amruz Cerna, Petr Taus, Veronika Pospisilova, Marketa Nezvedova, Veronika Fedorova, Sona Kadakova, Hana Klimova, Michaela Capandova, Petra Orviska, Petr Fojtik, Simona Bartova, Karla Plevova, Zdenek Spacil, Hana Hribkova, Dasa Bohaciakova
Pubblicato in: Cell Reports, Numero 42, 2024, Pagina/e 113310, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2023.113310

CSF biomarkers and plasma p‐tau181 as predictors of longitudinal tau accumulation: Implications for clinical trial design

Autori: Alexis Moscoso, Thomas K. Karikari, Michel J. Grothe, Nicholas J. Ashton, Juan Lantero‐Rodriguez, Anniina Snellman, Henrik Zetterberg, Kaj Blennow, Michael Schöll
Pubblicato in: Alzheimer's & Dementia, Numero 18, 2023, Pagina/e 2614-2626, ISSN 1552-5260
Editore: Elsevier BV
DOI: 10.1002/alz.12570

Motor symptoms in genetic frontotemporal dementia: developing a new module for clinical rating scales

Autori: Kiran Samra, Amy M. MacDougall, Georgia Peakman, Arabella Bouzigues, Martina Bocchetta, David M. Cash, Caroline V. Greaves, Rhian S. Convery, John C. van Swieten, Lize Jiskoot, Harro Seelaar, Fermin Moreno, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Mario Masellis, Carmela Tartaglia, James B. Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe
Pubblicato in: Journal of Neurology, Numero 270, 2023, Pagina/e 1466-1477, ISSN 0340-5354
Editore: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-022-11442-y

Antibody-free measurement of cerebrospinal fluid tau phosphorylation across the Alzheimer’s disease continuum

Autori: Johan Gobom, Andréa L. Benedet, Niklas Mattsson-Carlgren, Laia Montoliu-Gaya, Nina Schultz, Nicholas J. Ashton, Shorena Janelidze, Stijn Servaes, Mathias Sauer, Tharick A. Pascoal, Thomas K. Karikari, Juan Lantero-Rodriguez, Gunnar Brinkmalm, Henrik Zetterberg, Oskar Hansson, Pedro Rosa-Neto, Kaj Blennow
Pubblicato in: Molecular Neurodegeneration, Numero 17, 2022, ISSN 1750-1326
Editore: BioMed Central
DOI: 10.1186/s13024-022-00586-0

DreaMR: Diffusion-driven Counterfactual Explanation for Functional MRI

Autori: Hasan A. Bedel, Tolga Çukur
Pubblicato in: IEEE Transactions on Medical Imaging, 2024, Pagina/e 1-1, ISSN 0278-0062
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2024.3507008

Microglia and amyloid plaque formation in Alzheimer's disease – Evidence, possible mechanisms, and future challenges

Autori: Stefanie Fruhwürth, Henrik Zetterberg, Søren R. Paludan
Pubblicato in: Journal of Neuroimmunology, Numero 390, 2024, Pagina/e 578342, ISSN 0165-5728
Editore: Elsevier BV
DOI: 10.1016/j.jneuroim.2024.578342

Resource assessment in trials undertaken in residential care homes: Experiences from the Australian MIDDEL cluster randomised controlled trial research team

Autori: Felicity A. Baker, Phoebe A. Stretton-Smith, Tanara Vieira Sousa, Imogen Clark, Alice Cotton, Christian Gold, Young-Eun C. Lee
Pubblicato in: Contemporary Clinical Trials Communications, Numero 20, 2020, Pagina/e 100675, ISSN 2451-8654
Editore: Elsevier
DOI: 10.1016/j.conctc.2020.100675

Book of Abstracts ESMRMB 2024 Online 40th Annual Scientific Meeting 2–5 October 2024

Autori: Cetin AI, Turhan G, Padrela BE, Mahroo A, Konstandin S, Hoinkiss DC, Breutigam NJ, Keil V, Barkhof F, Danyeli AE, Ozduman K, Pamir MN, Eickel K, Mutsaerts HJMM, Petr J, Guenther M, Dincer A, Ozturk-Isik E
Pubblicato in: Magnetic Resonance Materials in Physics, Biology and Medicine, Numero 37, 2024, Pagina/e 1-781, ISSN 1352-8661
Editore: Springer
DOI: 10.1007/s10334-024-01191-6

Fluid Biomarkers for Synaptic Dysfunction and Loss

Autori: Elena Camporesi, Johanna Nilsson, Ann Brinkmalm, Bruno Becker, Nicholas J Ashton, Kaj Blennow, Henrik Zetterberg
Pubblicato in: Biomarker Insights, Numero 15, 2025, Pagina/e 117727192095031, ISSN 1177-2719
Editore: Libertas Academica
DOI: 10.1177/1177271920950319

Cerebrospinal fluid brevican and neurocan fragment patterns in human traumatic brain injury

Autori: Karolina Minta, Gunnar Brinkmalm, Eric P. Thelin, Faiez Al Nimer, Fredrik Piehl, Mats Tullberg, Anna Jeppsson, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Ulf Andreasson
Pubblicato in: Clinica Chimica Acta, Numero 512, 2021, Pagina/e 74-83, ISSN 0009-8981
Editore: Elsevier BV
DOI: 10.1016/j.cca.2020.11.017

Alzheimer’s disease-associated complement gene variants influence plasma complement protein levels

Autori: Aurora Veteleanu, Joshua Stevenson-Hoare, Samuel Keat, Nikoleta Daskoulidou, Henrik Zetterberg, Amanda Heslegrave, Valentina Escott-Price, Julie Williams, Rebecca Sims, Wioleta M. Zelek, Sarah M. Carpanini, Bryan Paul Morgan
Pubblicato in: Journal of Neuroinflammation, Numero 20, 2023, ISSN 1742-2094
Editore: BioMed Central
DOI: 10.1186/s12974-023-02850-6

Frailty trajectories in three longitudinal studies of aging: Is the level or the rate of change more predictive of mortality?

Autori: Ge Bai, Agnieszka Szwajda, Yunzhang Wang, Xia Li, Hannah Bower, Ida K Karlsson, Boo Johansson, Anna K Dahl Aslan, Nancy L Pedersen, Sara Hägg, Juulia Jylhävä
Pubblicato in: Age and Ageing, Numero 50, 2021, Pagina/e 2174-2182, ISSN 0002-0729
Editore: Oxford University Press
DOI: 10.1093/ageing/afab106

Plasma neurofilament light chain levels predict improvement in late phase after stroke

Autori: Anna Stokowska, Lina Bunketorp Käll, Christian Blomstrand, Joel Simrén, Michael Nilsson, Henrik Zetterberg, Kaj Blennow, Milos Pekny, Marcela Pekna
Pubblicato in: European Journal of Neurology, Numero 28, 2023, Pagina/e 2218-2228, ISSN 1351-5101
Editore: Blackwell Publishing Inc.
DOI: 10.1111/ene.14854

A guide for blood–brain barrier models

Autori: Yomna Soliman, Jana Al‐khodor, Gülnaz Yildirim Köken, Nur Mustafaoglu
Pubblicato in: FEBS Letters, Numero 599, 2025, Pagina/e 599-644, ISSN 0014-5793
Editore: Elsevier BV
DOI: 10.1002/1873-3468.15053

Addition of the FTD Module to the Neuropsychiatric Inventory improves classification of frontotemporal dementia spectrum disorders

Autori: Lize C. Jiskoot, Lucy L. Russell, Caroline V. Greaves, Esther van Schaik, Esther van den Berg, Jackie M. Poos, Liset de Boer, Laura Donker Kaat, Harro Seelaar, Yolande A. L. Pijnenburg, John C. van Swieten, Jonathan D. Rohrer
Pubblicato in: Journal of Neurology, Numero 270, 2023, Pagina/e 2674-2687, ISSN 0340-5354
Editore: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-023-11596-3

Clinical effectiveness of music interventions for dementia and depression in elderly care (MIDDEL): Australian cohort of an international pragmatic cluster-randomised controlled trial

Autori: Felicity A Baker, Young-Eun C Lee, Tanara Vieira Sousa, Phoebe A Stretton-Smith, Jeanette Tamplin, Vigdis Sveinsdottir, Monika Geretsegger, Jo Dugstad Wake, Jörg Assmus, Christian Gold
Pubblicato in: The Lancet Healthy Longevity, Numero 3, 2024, Pagina/e e153-e165, ISSN 2666-7568
Editore: ELSEVIER
DOI: 10.1016/s2666-7568(22)00027-7

Prediction of future Alzheimer’s disease dementia using plasma phospho-tau combined with other accessible measures

Autori: Sebastian Palmqvist, Pontus Tideman, Nicholas Cullen, Henrik Zetterberg, Kaj Blennow, null null, Jeffery L. Dage, Erik Stomrud, Shorena Janelidze, Niklas Mattsson-Carlgren, Oskar Hansson
Pubblicato in: Nature Medicine, Numero 27, 2023, Pagina/e 1034-1042, ISSN 1078-8956
Editore: Nature Publishing Group
DOI: 10.1038/s41591-021-01348-z

Blood-based biomarkers for Alzheimer's disease: towards clinical implementation

Autori: Charlotte E Teunissen, Inge M W Verberk, Elisabeth H Thijssen, Lisa Vermunt, Oskar Hansson, Henrik Zetterberg, Wiesje M van der Flier, Michelle M Mielke, Marta del Campo
Pubblicato in: The Lancet Neurology, Numero 21, 2023, Pagina/e 66-77, ISSN 1474-4422
Editore: The Lancet Publishing Group
DOI: 10.1016/s1474-4422(21)00361-6

Clinical performance and head-to-head comparison of CSF p-tau235 with p-tau181, p-tau217 and p-tau231 in two memory clinic cohorts

Autori: Juan Lantero-Rodriguez, Agathe Vrillon, Aida Fernández-Lebrero, Paula Ortiz-Romero, Anniina Snellman, Laia Montoliu-Gaya, Wagner S. Brum, Emmanuel Cognat, Julien Dumurgier, Albert Puig-Pijoan, Irene Navalpotro-Gómez, Greta García-Escobar, Thomas K. Karikari, Eugeen Vanmechelen, Nicholas J. Ashton, Henrik Zetterberg, Marc Suárez-Calvet, Claire Paquet, Kaj Blennow
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Plasma protein profiling reveals novel specific biomarkers reflecting the multifactorial nature of Alzheimer´s disease continuum

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A Western‐style dietary pattern is associated with cerebrospinal fluid biomarker levels for preclinical Alzheimer's disease—A population‐based cross‐sectional study among 70‐year‐olds

Autori: Jessica Samuelsson, Silke Kern, Henrik Zetterberg, Kaj Blennow, Elisabet Rothenberg, Ola Wallengren, Ingmar Skoog, Anna Zettergren
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What does heritability of Alzheimer’s disease represent?

Autori: Emily Baker, Ganna Leonenko, Karl Michael Schmidt, Matthew Hill, Amanda J. Myers, Maryam Shoai, Itziar de Rojas, Niccoló Tesi, Henne Holstege, Wiesje M. van der Flier, Yolande A. L. Pijnenburg, Agustin Ruiz, John Hardy, Sven van der Lee, Valentina Escott-Price
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Stratifying the Presymptomatic Phase of Genetic Frontotemporal Dementia by Serum<scp>NfL</scp>and<scp>pNfH</scp>: A Longitudinal Multicentre Study

Autori: Carlo Wilke, Selina Reich, John C. van Swieten, Barbara Borroni, Raquel Sanchez‐Valle, Fermin Moreno, Robert Laforce, Caroline Graff, Daniela Galimberti, James B. Rowe, Mario Masellis, Maria C. Tartaglia, Elizabeth Finger, Rik Vandenberghe, Alexandre de Mendonça, Fabrizio Tagliavini, Isabel Santana, Simon Ducharme, Chris R. Butler, Alexander Gerhard, Johannes Levin, Adrian Danek, Markus Otto, G
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Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative

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TDP-43 proteinopathies: a new wave of neurodegenerative diseases

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New cases of dementia are rising in elderly populations in Wales, UK

Autori: Joshua Stevenson-Hoare, Ann-Kathrin Schalkamp, Cynthia Sandor, John Hardy, Valentina Escott-Price
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Transient Changes in the Plasma of Astrocytic and Neuronal Injury Biomarkers in COVID-19 Patients without Neurological Syndromes

Autori: Matthew P. Lennol, Nicholas J. Ashton, Oscar Moreno-Pérez, María-Salud García-Ayllón, Jose-Manuel Ramos-Rincon, Mariano Andrés, José-Manuel León-Ramírez, Vicente Boix, Joan Gil, Kaj Blennow, Esperanza Merino, Henrik Zetterberg, Javier Sáez-Valero
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Central nervous system monoaminergic activity in hip osteoarthritis patients with disabling pain: associations with pain severity and central sensitization

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Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling

Autori: Luana Naia, Catarina M. Pinho, Giacomo Dentoni, Jianping Liu, Nuno Santos Leal, Duarte M. S. Ferreira, Bernadette Schreiner, Riccardo Filadi, Lígia Fão, Niamh M. C. Connolly, Pontus Forsell, Gunnar Nordvall, Makoto Shimozawa, Elisa Greotti, Emy Basso, Pierre Theurey, Anna Gioran, Alvin Joselin, Marie Arsenian-Henriksson, Per Nilsson, A. Cristina Rego, Jorge L. Ruas, David Park, Daniele Bano, Pao
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Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer’s disease neuropathology

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Predicting neurological outcome after out-of-hospital cardiac arrest with cumulative information; development and internal validation of an artificial neural network algorithm

Autori: Peder Andersson, Jesper Johnsson, Ola Björnsson, Tobias Cronberg, Christian Hassager, Henrik Zetterberg, Pascal Stammet, Johan Undén, Jesper Kjaergaard, Hans Friberg, Kaj Blennow, Gisela Lilja, Matt P. Wise, Josef Dankiewicz, Niklas Nielsen, Attila Frigyesi
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Characterization of pre‐analytical sample handling effects on a panel of Alzheimer's disease–related blood‐based biomarkers: Results from the Standardization of Alzheimer's Blood Biomarkers (SABB) working group

Autori: Inge M. W. Verberk, Els O. Misdorp, Jannet Koelewijn, Andrew J. Ball, Kaj Blennow, Jeffrey L. Dage, Noelia Fandos, Oskar Hansson, Christophe Hirtz, Shorena Janelidze, Sungmin Kang, Kristopher Kirmess, Jana Kindermans, Ryan Lee, Matthew R. Meyer, Dandan Shan, Leslie M. Shaw, Teresa Waligorska, Tim West, Henrik Zetterberg, Rebecca M. Edelmayer, Charlotte E. Teunissen
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Prevalence and Clinical Implications of a β-Amyloid–Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease

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α-Synuclein seed amplification assay as a diagnostic tool for parkinsonian disorders

Autori: Bárbara Fernandes Gomes, Carly M. Farris, Yihua Ma, Luis Concha-Marambio, Russ Lebovitz, Bengt Nellgård, Keti Dalla, Julius Constantinescu, Radu Constantinescu, Johan Gobom, Ulf Andreasson, Henrik Zetterberg, Kaj Blennow
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Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services—part 4 of 6

Autori: Alina Solomon, Ruth Stephen, Daniele Altomare, Emmanuel Carrera, Giovanni B. Frisoni, Jenni Kulmala, José Luis Molinuevo, Peter Nilsson, Tiia Ngandu, Federica Ribaldi, Bruno Vellas, Philip Scheltens, Miia Kivipelto, null null, Marc Abramowicz, Daniele Altomare, Frederik Barkhof, Marcelo Berthier, Melanie Bieler, Kaj Blennow, Carol Brayne, Andrea Brioschi, Emmanuel Carrera, Gael Chételat, Chantal
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Molecular Structure of Cu(II)-Bound Amyloid-β Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer’s Disease

Autori: Axel Abelein, Simone Ciofi-Baffoni, Cecilia Mörman, Rakesh Kumar, Andrea Giachetti, Mario Piccioli, Henrik Biverstål
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What do data‐driven Alzheimer’s disease subtypes tell us about white matter pathology and clinical progression?

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Sixteen-Year Longitudinal Evaluation of Blood-Based DNA Methylation Biomarkers for Early Prediction of Alzheimer’s Disease

Autori: Fernanda Schäfer Hackenhaar, null null, Maria Josefsson, Annelie Nordin Adolfsson, Mattias Landfors, Karolina Kauppi, Tenielle Porter, Lidija Milicic, Simon M. Laws, Magnus Hultdin, Rolf Adolfsson, Sofie Degerman, Sara Pudas
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Cerebrospinal fluid markers of inflammation and brain injury in Lyme neuroborreliosis – a prospective follow-up study

Autori: Ivar Tjernberg, Paula Gyllemark, Henrik Zetterberg, Kaj Blennow, Jan Ernerudh, Pia Forsberg, Johanna Sjöwall, Anna J. Henningsson
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Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation

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Health status and risk profiles for brain aging of rural‐dwelling older adults: Data from the interdisciplinary baseline assessments in MIND‐China

Autori: Yongxiang Wang, Xiaolei Han, Xianda Zhang, Zhonglin Zhang, Lin Cong, Shi Tang, Tingting Hou, Cuicui Liu, Xiaojuan Han, Qinghua Zhang, Jianli Feng, Ling Yin, Lin Song, Yi Dong, Rui Liu, Yuanjing Li, Tiia Ngandu, Miia Kivipelto, Heather Snyder, Maria Carrillo, Jonas Persson, Laura Fratiglioni, Lenore J Launer, Jianping Jia, Yifeng Du, Chengxuan Qiu
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Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease

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Attitudes of at-risk older adults about prevention of cardiovascular disease and dementia using eHealth: a qualitative study in a European context

Autori: Ulrika Akenine, Mariagnese Barbera, Cathrien RL Beishuizen, Mandana Fallah Pour, Juliette Guillemont, Anna Rosenberg, Nicola Coley, Francesca Mangialasche, Lotta Salo, Stephanie Savy, A Jeannette Pols, Sandrine Andrieu, Edo Richard, Hilkka Soininen, Eric Moll van Charante, Miia Kivipelto
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Compliance with National and International Guidelines in the Treatment of Nonmotor Symptoms in Late-Stage Parkinson’s Disease

Autori: Kristina Rosqvist, Per Odin
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A Plug-In Graph Neural Network to Boost Temporal Sensitivity in fMRI Analysis

Autori: Irmak Sivgin, Hasan Atakan Bedel, Saban Ozturk, Tolga Çukur
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A glycan epitope correlates with tau in serum and predicts progression to Alzheimer's disease in combination with APOE4 allele status

Autori: Robin Ziyue Zhou, Davide Liborio Vetrano, Giulia Grande, Frida Duell, Linus Jönsson, Erika J Laukka, Claudia Fredolini, Bengt Winblad, Lars Tjernberg, Sophia Schedin‐Weiss
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Dynamics of Selected Biomarkers in Cerebrospinal Fluid During Complex Endovascular Aortic Repair – A Pilot Study

Autori: Gísli Gunnar Jónsson, Niklas Marklund, Kaj Blennow, Henrik Zetterberg, Anders Wanhainen, David Lindström, Jacob Eriksson, Kevin Mani
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Comparison of long-term effects of metformin on longevity between people with type 2 diabetes and matched non-diabetic controls

Autori: Joshua Stevenson-Hoare, Ganna Leonenko, Valentina Escott-Price
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Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A consensus statement

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Plasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects

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Neurodegenerative disease of the brain: a survey of interdisciplinary approaches

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Looking beneath the surface: the importance of subcortical structures in frontotemporal dementia

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No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington’s disease

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Decreased Electroencephalography Global Field Synchronization in Slow-Frequency Bands Characterizes Synaptic Dysfunction in Amnestic Subtypes of Mild Cognitive Impairment

Autori: Una Smailovic, Daniel Ferreira, Birgitta Ausén, Nicholas James Ashton, Thomas Koenig, Henrik Zetterberg, Kaj Blennow, Vesna Jelic
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Cerebrospinal fluid N-224 tau helps discriminate Alzheimer’s disease from subjective cognitive decline and other dementias

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Synaptotagmin 13 is neuroprotective across motor neuron diseases

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Reproductive period and preclinical cerebrospinal fluid markers for Alzheimer disease: a 25-year study

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ASIC-E4: Interplay of Beta-Amyloid, Synaptic Density and Neuroinflammation in Cognitively Normal Volunteers With Three Levels of Genetic Risk for Late-Onset Alzheimer's Disease – Study Protocol and Baseline Characteristics

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Critical illness polyneuropathy, myopathy and neuronal biomarkers in COVID-19 patients: A prospective study

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Sleep disturbances and the speed of multimorbidity development in old age: results from a longitudinal population-based study

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Robust Multi-TE ASL-Based Blood–Brain Barrier Integrity Measurements

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The genetic regulation of protein expression in cerebrospinal fluid

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Brain injury markers in new-onset seizures in adults: A pilot study

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Aging, sex, metabolic and life experience factors: Contributions to neuro-inflammaging in Alzheimer’s disease research

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Multidomain Interventions to Prevent Cognitive Impairment, Alzheimer's Disease, and Dementia: From FINGER to World-Wide FINGERS

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Hypotension during transsphenoidal pituitary surgery associated with increase in plasma levels of brain injury markers

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Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies

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Correlative Chemical Imaging and Spatial Chemometrics Delineate Alzheimer Plaque Heterogeneity at High Spatial Resolution

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Blood biomarkers for neuroaxonal injury and astrocytic activation in chemotherapy-induced peripheral neuropathy

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Melatonin: A potential nighttime guardian against Alzheimer’s

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A prospective feasibility trial exploring novel biomarkers for neurotoxicity after isolated limb perfusion

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Tissue specific LRRK2 interactomes reveal a distinct striatal functional unit

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Plasma biomarkers of Alzheimer’s disease improve prediction of cognitive decline in cognitively unimpaired elderly populations

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Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis

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Structural basis of epitope recognition by anti-alpha-synuclein antibodies MJFR14-6-4-2

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Extracellular fluid, cerebrospinal fluid and plasma biomarkers of axonal and neuronal injury following intracerebral hemorrhage

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Cavity Lasing Characteristics of Thioflavin T and Thioflavin X in Different Solvents and Their Interaction with DNA for the Controlled Reduction of a Light Amplification Threshold in Solid-State Biofilms

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Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

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Quantification of the trans-synaptic partners neurexin-neuroligin in CSF of neurodegenerative diseases by parallel reaction monitoring mass spectrometry

Autori: Elena Camporesi, Johanna Nilsson, Agathe Vrillon, Emmanuel Cognat, Claire Hourregue, Henrik Zetterberg, Kaj Blennow, Bruno Becker, Ann Brinkmalm, Claire Paquet, Gunnar Brinkmalm
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Blood–Brain Barrier Disruption and Its Involvement in Neurodevelopmental and Neurodegenerative Disorders

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Brevican and Neurocan Peptides as Potential Cerebrospinal Fluid Biomarkers for Differentiation Between Vascular Dementia and Alzheimer’s Disease

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Gray matter hypoperfusion is a late pathological event in the course of Alzheimer’s disease

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No neurochemical evidence of neuronal injury or glial activation in children with Paediatric Acute-onset Neuropsychiatric Syndrome. An explorative pilot study

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LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy

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Genome‐wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer

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The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia: A GENFI study

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Blood β‐synuclein is related to amyloid PET positivity in memory clinic patients

Autori: Patrick Oeckl, Marina Bluma, Marco Bucci, Steffen Halbgebauer, Konstantinos Chiotis, Anna Sandebring‐Matton, Nicholas J. Ashton, Guglielmo Di Molfetta, Lana Grötschel, Miia Kivipelto, Kaj Blennow, Henrik Zetterberg, Irina Savitcheva, Agneta Nordberg, Markus Otto
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Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer’s disease

Autori: Joana B Pereira, Shorena Janelidze, Ruben Smith, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Charlotte E Teunissen, Henrik Zetterberg, Erik Stomrud, Nicholas J Ashton, Kaj Blennow, Oskar Hansson
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Tilavonemab in early Alzheimer’s disease: results from a phase 2, randomized, double-blind study

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Single-cell and spatial transcriptomics enables probabilistic inference of cell type topography

Autori: Alma Andersson, Joseph Bergenstråhle, Michaela Asp, Ludvig Bergenstråhle, Aleksandra Jurek, José Fernández Navarro, Joakim Lundeberg
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Plasma neurofilament light chain protein is not increased in forensic psychiatric populations: a pilot study

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Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes

Autori: Claudia Cicognola, Niklas Mattsson-Carlgren, Danielle van Westen, Henrik Zetterberg, Kaj Blennow, Sebastian Palmqvist, Khazar Ahmadi, Olof Strandberg, Erik Stomrud, Shorena Janelidze, Oskar Hansson
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Preanalytical stability of plasma/serum brain‐derived tau

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A co-culture model system to quantify antibody-dependent cellular cytotoxicity in human breast cancer cells using an engineered natural killer cell line

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Global Prevalence of Young-Onset Dementia

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Circumventing the packaging limit of AAV-mediated gene replacement therapy for neurological disorders

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Associations of Fully Automated CSF and Novel Plasma Biomarkers With Alzheimer Disease Neuropathology at Autopsy

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CSF biomarkers of neurotoxicity in childhood cancer survivors after cranial radiotherapy or surgery

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Biomarkers of brain injury after cardiac arrest; a statistical analysis plan from the TTM2 trial biobank investigators

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CSF p-tau205: a biomarker of tau pathology in Alzheimer’s disease

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A Solve-RD ClinVar-based reanalysis of 1522 index cases from ERN-ITHACA reveals common pitfalls and misinterpretations in exome sequencing

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An accurate fully automated panel of plasma biomarkers for Alzheimer's disease

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CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired individuals

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Effects of Meditation Training and Non-Native Language Training on Cognition in Older Adults

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Neuropsychiatric symptoms in genetic frontotemporal dementia: developing a new module for Clinical Rating Scales

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Plasma neurofilament light protein correlates with diffusion tensor imaging metrics in frontotemporal dementia

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Differential seeding and propagating efficiency of α-synuclein strains generated in different conditions

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Targeting the GBA1 pathway to slow Parkinson disease: Insights into clinical aspects, pathogenic mechanisms and new therapeutic avenues

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Assessing the commutability of candidate reference materials for the harmonization of neurofilament light measurements in blood

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Longitudinal cerebral perfusion in presymptomatic genetic frontotemporal dementia: GENFI results

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Transcriptomics and weighted protein network analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson’s Disease

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High levels of kappa free light chain synthesis predict cognitive decline in relapsing-remitting multiple sclerosis

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Spatial neurolipidomics—MALDI mass spectrometry imaging of lipids in brain pathologies

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Cerebrospinal fluid proteomics in patients with Alzheimer’s disease reveals five molecular subtypes with distinct genetic risk profiles

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Spatial RNA Sequencing Identifies Robust Markers of Vulnerable and Resistant Human Midbrain Dopamine Neurons and Their Expression in Parkinson’s Disease

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Nutrition guidance within a multimodal intervention improves diet quality in prodromal Alzheimer’s disease: Multimodal Preventive Trial for Alzheimer’s Disease (MIND-ADmini)

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Alzheimer‐like biomarker heterogeneity in a preclinical elderly birth cohort: Insight46

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SOD1 mutations associated with amyotrophic lateral sclerosis analysis of variant severity

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Novel avenues of tau research

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Transcriptomic and epigenomic profiling reveals altered responses to diesel emissions in Alzheimer's disease both in vitro and in population‐based data

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Exploring the Genotype–Phenotype Correlation in GBA-Parkinson Disease: Clinical Aspects, Biomarkers, and Potential Modifiers

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Blood biomarkers for Alzheimer's disease and related disorders

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Blood biomarkers for Alzheimer’s disease in clinical practice and trials

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Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer’s disease

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Genetic variations in GBA1 and LRRK2 genes: Biochemical and clinical consequences in Parkinson disease

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Plasma Aβ42/40 ratio, p‐tau181, GFAP, and NfL across the Alzheimer's disease continuum: A cross‐sectional and longitudinal study in the AIBL cohort

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Brain-derived tau: a novel blood-based biomarker for Alzheimer’s disease-type neurodegeneration

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SLITRK2, an X-linked modifier of the age at onset in C9orf72 frontotemporal lobar degeneration

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Genome-wide association studies for Alzheimer’s disease: bigger is not always better

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Cynomolgus Monkeys With Spontaneous Type-2-Diabetes-Mellitus-Like Pathology Develop Alpha-Synuclein Alterations Reminiscent of Prodromal Parkinson’s Disease and Related Diseases

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Correlative Chemical Imaging Identifies Amyloid Peptide Signatures of Neuritic Plaques and Dystrophy in Human Sporadic Alzheimer's Disease

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A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study

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Correction to: Probability of Alzheimer’s disease based on common and rare genetic variants

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Perspectives on Care for Late-Stage Parkinson’s Disease

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Exposure to source-specific air pollution in residential areas and its association with dementia incidence: a cohort study in Northern Sweden

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Cerebrospinal fluid biomarker panel of synaptic dysfunction in Alzheimer's disease and other neurodegenerative disorders

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Identifying the neurodevelopmental and psychiatric signatures of genomic disorders associated with intellectual disability: a machine learning approach

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Biomarkers of Alzheimer’s Disease and Cerebrovascular Disease in Relation to Depressive Symptomatology in Individuals With Subjective Cognitive Decline

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Intranasal administration of α-synuclein preformed fibrils triggers microglial iron deposition in the substantia nigra of Macaca fascicularis

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Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers

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A Non-APOE Polygenic Risk Score for Alzheimer’s Disease Is Associated With Cerebrospinal Fluid Neurofilament Light in a Representative Sample of Cognitively Unimpaired 70-Year Olds

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Proportion of Community-Dwelling Individuals Older Than 70 Years Eligible for Lecanemab Initiation

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Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum

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Abilities of the BRICHOS domain to prevent neurotoxicity and fibril formation are dependent on a highly conserved Asp residue

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Biomarkers of brain injury in patients with stress-related exhaustion: A longitudinal study

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Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids

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Predicting Alzheimer's disease progression: Results from the TADPOLE Challenge

Autori: Razvan V. Marinescu, Esther E. Bron, Neil P. Oxtoby, Alexandra L. Young, Arthur W. Toga, Michael W. Weiner, Frederik Barkhof, Nick C. Fox, Polina Golland, Stefan Klein, Daniel C. Alexander
Pubblicato in: Alzheimer's & Dementia, Numero 16, 2023, ISSN 1552-5260
Editore: Elsevier BV
DOI: 10.1002/alz.039538

Polygenic risk scores for Alzheimer's disease are related to dementia risk in APOE ɛ4 negatives

Autori: Jenna Najar, Sven J. van der Lee, Erik Joas, Hanna Wetterberg, John Hardy, Rita Guerreiro, Jose Bras, Margda Waern, Silke Kern, Henrik Zetterberg, Kaj Blennow, Ingmar Skoog, Anna Zettergren
Pubblicato in: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Numero 13, 2023, ISSN 2352-8729
Editore: WILEY
DOI: 10.1002/dad2.12142

The architecture of abnormal reward behaviour in dementia: multimodal hedonic phenotypes and brain substrate

Autori: Anthipa Chokesuwattanaskul, Harmony Jiang, Rebecca L Bond, Daniel A Jimenez, Lucy L Russell, Harri Sivasathiaseelan, Jeremy C S Johnson, Elia Benhamou, Jennifer L Agustus, Janneke E P van Leeuwen, Peerapat Chokesuwattanaskul, Chris J D Hardy, Charles R Marshall, Jonathan D Rohrer, Jason D Warren
Pubblicato in: Brain Communications, Numero 5, 2023, ISSN 2632-1297
Editore: OXFORD UNIVERSITY PRESS
DOI: 10.1093/braincomms/fcad027

Longitudinal Cognitive Changes in Genetic Frontotemporal Dementia Within the GENFI Cohort

Autori: Jackie M. Poos, Amy MacDougall, Esther van den Berg, Lize C. Jiskoot, Janne M. Papma, Emma L. van der Ende, Harro Seelaar, Lucy L. Russell, Georgia Peakman, Rhian Convery, Yolande A.L. Pijnenburg, Fermin Moreno, Raquel Sanchez-Valle, Barbara Borroni, Robert Laforce, Marie-Claire Doré, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Daniela Galimberti, James B. Rowe, Elizabeth Finger, Mat
Pubblicato in: Neurology, Numero 99, 2024, ISSN 0028-3878
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000200384

Accurate Bayesian segmentation of thalamic nuclei using diffusion MRI and an improved histological atlas

Autori: Henry F.J. Tregidgo, Sonja Soskic, Juri Althonayan, Chiara Maffei, Koen Van Leemput, Polina Golland, Ricardo Insausti, Garikoitz Lerma-Usabiaga, César Caballero-Gaudes, Pedro M. Paz-Alonso, Anastasia Yendiki, Daniel C. Alexander, Martina Bocchetta, Jonathan D. Rohrer, Juan Eugenio Iglesias
Pubblicato in: NeuroImage, Numero 274, 2024, Pagina/e 120129, ISSN 1053-8119
Editore: Academic Press
DOI: 10.1016/j.neuroimage.2023.120129

Associations between misfolded alpha‐synuclein aggregates and Alzheimer's disease pathology in vivo

Autori: Alexa Pichet Binette, Angela Mammana, Laura Wisse, Marcello Rossi, Olof Strandberg, Ruben Smith, Niklas Mattsson‐Carlgren, Shorena Janelidze, Sebastian Palmqvist, null null, Alice Ticca, Erik Stomrud, Piero Parchi, Oskar Hansson
Pubblicato in: Alzheimer's & Dementia, Numero 20, 2024, Pagina/e 7624-7634, ISSN 1552-5260
Editore: Elsevier BV
DOI: 10.1002/alz.14225

Cardiovascular health metrics from mid- to late-life and risk of dementia: A population-based cohort study in Finland

Autori: Yajun Liang, Tiia Ngandu, Tiina Laatikainen, Hilkka Soininen, Jaakko Tuomilehto, Miia Kivipelto, Chengxuan Qiu
Pubblicato in: PLOS Medicine, Numero 17, 2020, Pagina/e e1003474, ISSN 1549-1676
Editore: PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pmed.1003474

Creating the Pick’s disease International Consortium: Association study ofMAPTH2 haplotype with risk of Pick’s disease

Autori: Rebecca R Valentino, William J Scotton, Shanu F Roemer, Tammaryn Lashley, Michael G Heckman, Maryam Shoai, Alejandro Martinez-Carrasco, Nicole Tamvaka, Ronald L Walton, Matthew C Baker, Hannah L Macpherson, Raquel Real, Alexandra I Soto-Beasley, Kin Mok, Tamas Revesz, Thomas T Warner, Zane Jaunmuktane, Bradley F Boeve, Elizabeth A Christopher, Michael DeTure, Ranjan Duara, Neill R Graff-Radford, K
Pubblicato in: MEDRXIV THE PREPRINT SERVER FOR HEALTH SCIENCES, 2023
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.04.17.23288471

Symptom-led staging for primary progressive aphasia

Autori: Chris JD Hardy, Cathleen Taylor-Rubin, Beatrice Taylor, Emma Harding, Aida Suarez Gonzalez, Jessica Jiang, Laura Thompson, Rachel Kingma, Anthipa Chokesuwattanaskul, Ffion Walker, Suzie Barker, Emilie Brotherhood, Claire Waddington, Olivia Wood, Nikki Zimmermann, Nuriye Kupeli, Keir XX Yong, Paul M Camic, Josh Stott, Charles R Marshall, Neil P. Oxtoby, Jonathan D Rohrer, Anna Volkmer, Sebastian J
Pubblicato in: MEDRXIV THE PREPRINT SERVER FOR HEALTH SCIENCES, 2023
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.03.13.23286972

Differential Impairment of Cerebrospinal Fluid Synaptic Biomarkers in the Genetic Forms of Frontotemporal Dementia

Autori: Aitana Sogorb-Esteve, Johanna Nilsson, Imogen J Swift, Carolin Heller, Lucy L Russell, Georgia Peakman, Rhian S Convery, John C van Swieten, Harro Seelaar, Barbara Borroni, Daniela Galimberti, Raquel Sánchez-Valle, Robert Laforce, Fermin Moreno, Matthis Synofzik, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Rik Vanderberghe, Elisabeth Finger, Fabrizio Tagliavini, Isabel
Pubblicato in: RESEARCH SQUARE PREPRINTS, 2022
Editore: Research Square Platform LLC, SPRINGER NATURE
DOI: 10.21203/rs.3.rs-1188941/v1

Leveraging long-term smartwatch data to inform Parkinson’s disease progression, subtypes, and risk

Autori: Ann-Kathrin Schalkamp, Kathryn J Peall, Neil A Harrison, Valentina Escott-Price, Cynthia Sandor
Pubblicato in: MEDRXIV THE PREPRINT SERVER FOR HEALTH SCIENCES, 2023
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.09.13.23295404

Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementia

Autori: Aurélie Bussy, Jake Levy, Tristin Best, Raihaan Patel, Lani Cupo, Tim Van Langenhove, Jorgen Nielsen, Yolande Pijnenburg, Maria Landqvist Waldö, Anne Remes, Matthias L Schroeter, Isabel Santana, Florence Pasquier, Markus Otto, Adrian Danek, Johannes Levin, Isabelle Le Ber, Rik Vandenberghe, Matthis Synofzik, Fermin Moreno, Alexandre de Mendonça, Raquel Sanchez-Valle, Robert Laforce, Tobias Lang
Pubblicato in: BIORXIV THE PREPRINT SERVER FOR BIOLOGY, 2024
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.11.12.468429

Revealing nervous and cardiac system interactions by iPSC-Based platforms

Autori: Ozlem Mutlu Burnaz, Esra Cagavi
Pubblicato in: iPSCs - State of the Science, Numero Volume 16, 2022, Pagina/e 1-28
Editore: Elsevier
DOI: 10.1016/b978-0-323-85767-3.00002-5

Domain-Agnostic Segmentation of Thalamic Nuclei from Joint Structural and Diffusion MRI

Autori: Henry F. J. Tregidgo, Sonja Soskic, Mark D. Olchanyi, Juri Althonayan, Benjamin Billot, Chiara Maffei, Polina Golland, Anastasia Yendiki, Daniel C. Alexander, Martina Bocchetta, Jonathan D. Rohrer, Juan Eugenio Iglesias
Pubblicato in: Lecture Notes in Computer Science, Medical Image Computing and Computer Assisted Intervention – MICCAI 2023, 2024, Pagina/e 247-257
Editore: Springer Nature Switzerland
DOI: 10.1007/978-3-031-43993-3_24

The Emerging Role of AI in Dementia Research and Healthcare

Autori: Janice M. Ranson, Magda Bucholc, Donald Lyall, Danielle Newby, Laura Winchester, Neil Oxtoby, Michele Veldsman, Timothy Rittman, Sarah Marzi, Nathan Skene, Ahmad Al Khleifat, Isabelle Foote, Vasiliki Orgeta, Andrey Kormilitzin, David J. Llewellyn
Pubblicato in: Brain Informatics and Health, Artificial Intelligence in Healthcare, 2024, Pagina/e 95-106
Editore: Springer Nature Singapore
DOI: 10.1007/978-981-19-5272-2_4

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