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CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular Disease

Project description

Innovative gene therapy for the treatment of heart failure and myocardial ischemia

According to WHO estimates, 17.7 million people die each year from cardiovascular disease (CVD), which constitutes more than 30 % of all deaths worldwide. Recent advances in biomedical research improved our understanding of the molecular and cellular mechanisms of the disease and introduced efficient and safer gene therapy vectors for the development of next-generation advanced therapy medicinal products (ATMPs) for CVD. The EU-funded CardioReGenix project focuses on technological innovations for the treatment of heart failure and myocardial ischemia. The goal is to overcome obstacles in CVD gene therapy, capitalising on robust preliminary data and multi-disciplinary consortium know-how in vector development, preclinical and clinical cardiology, business development and clinical translation.

Call for proposal

H2020-SC1-BHC-2018-2020

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Sub call

H2020-SC1-2018-Single-Stage-RTD

Coordinator

VRIJE UNIVERSITEIT BRUSSEL
Net EU contribution
€ 2 314 025,49
Address
Pleinlaan 2
1050 Brussel
Belgium

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Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (12)

ITA-SUOMEN YLIOPISTO
Finland
Net EU contribution
€ 2 566 115,25
Address
Yliopistonranta 1 E
70211 Kuopio

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Region
Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Savo
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
A2F ASSOCIATES LIMITED
United Kingdom
Net EU contribution
€ 718 295,00
Address
7 Laureate Paddocks
CB8 0AP Newmarket

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
East of England East Anglia Suffolk
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
MEDIZINISCHE HOCHSCHULE HANNOVER
Germany
Net EU contribution
€ 1 193 622,50
Address
Carl-neuberg-strasse 1
30625 Hannover

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Region
Niedersachsen Hannover Region Hannover
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
KING'S COLLEGE LONDON
United Kingdom
Net EU contribution
€ 1 013 675,00
Address
Strand
WC2R 2LS London

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Region
London Inner London — West Westminster
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
THE UNIVERSITY OF EDINBURGH
United Kingdom
Net EU contribution
€ 1 424 113,75
Address
Old College, South Bridge
EH8 9YL Edinburgh

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Region
Eastern Scotland Edinburgh
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
STICHTING VUMC
Netherlands
Net EU contribution
€ 1 106 750,75
Address
De Boelelaan 1117
1081 HV Amsterdam

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Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Research Organisations
Non-EU contribution
€ 0,00
BATAVIA BIOSCIENCES BV
Netherlands
Net EU contribution
€ 955 907,50
Address
Zernikedreef 16
2333 CL Leiden

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
FINVECTOR OY

Participation ended

Finland
Net EU contribution
€ 239 707,51
Address
Microkatu 1 S
70210 Kuopio

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Region
Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Savo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
CARDIOR PHARMACEUTICALS GMBH
Germany
Net EU contribution
€ 908 249,50
Address
Feodor Lynen Str 15
30625 Hannover

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Niedersachsen Hannover Region Hannover
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
ASPHALION SL
Spain
Net EU contribution
€ 310 035,00
Address
Calle Tarragona, Numeros 151-157, Planta 10, Bloqu
08014 Barcelona

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Este Cataluña Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
POHJOIS-SAVON SAIRAANHOITOPIIRIN KUNTAYHTYMA
Finland
Net EU contribution
€ 677 750,00
Address
Pl 100
70029 Kys

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Region
Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Savo
Activity type
Research Organisations
Non-EU contribution
€ 0,00
CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL
Germany
Net EU contribution
€ 1 411 526,25
Address
Olshausenstrasse 40
24118 Kiel

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Region
Schleswig-Holstein Schleswig-Holstein Kiel, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00