Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients with Bone Metastasis

Project Information

FURTHER

Grant agreement ID: 825859

DOI

10.3030/825859

Project closed

EC signature date 5 December 2018

Start date 1 January 2019

End date 31 December 2025

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost

€ 4 018 187,50

EU contribution

€ 3 998 125,00

Coordinated by

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (19)

Reproducibility and stability of spirometer‐guided deep inspiration breath‐hold in left‐breast treatments using an optical surface monitoring system

Author(s): Savino Cilla, Carmela Romano, Maurizio Craus, Pietro Viola, Gabriella Macchia, Mariangela Boccardi, Livia P. De Vivo, Milly Buwenge, Alessio G. Morganti, Francesco Deodato
Published in: Journal of Applied Clinical Medical Physics, Issue 24, 2023, ISSN 1526-9914
Publisher: American Institute of Physics
DOI: 10.1002/acm2.13922

Impact of Pain Education on Pain Relief in Oncological Patients: A Narrative Review of Systematic Reviews and Meta-Analyses

Author(s): Erika Galietta, Costanza M. Donati, Alberto Bazzocchi, Rebecca Sassi, Arina A. Zamfir, Renée Hovenier, Clemens Bos, Nikki Hendriks, Martijn F. Boomsma, Mira Huhtala, Roberto Blanco Sequeiros, Holger Grüll, Simone Ferdinandus, Helena M. Verkooijen, Alessio G. Morganti
Published in: Cancers, Issue 17, 2025, Page(s) 1683, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers17101683

Course of quality of life in short- and long-term survivors after radiotherapy for bone metastases

Author(s): Eline H. Huele, Renée Hovenier, Bas B.J. Bindels, Anouk van Oss, Rene H. Kuijten, Roxanne Gal, Bart J. Pielkenrood, Jorrit-Jan Verlaan, Nicolien Kasperts, Wietse S.C. Eppinga, Yvette M. van der Linden, Joanne M. van der Velden, Helena M. Verkooijen
Published in: Radiotherapy and Oncology, Issue 214, 2026, Page(s) 111284, ISSN 0167-8140
Publisher: Elsevier BV
DOI: 10.1016/j.radonc.2025.111284

Early economic modeling of magnetic resonance image-guided high intensity focused ultrasound compared to radiotherapy for pain palliation of bone metastases

Author(s): Julia Simões Corrêa Galendi, Sin Yuin Yeo, Holger Grüll, Grischa Bratke, Dennis Akuamoa-Boateng, Christian Baues, Clemens Bos, Helena M. Verkooijen, Arim Shukri, Stephanie Stock, Dirk Müller
Published in: Frontiers in Oncology, Issue 12, 2022, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.987546

Focused Ultrasound and RadioTHERapy for Non-Invasive Palliative Pain Treatment in Patients with Bone Metastasis: A Study Protocol for the Three Armed Randomized Controlled FURTHER-trial

Author(s): Marcia Bartels, Cyril Ferrer, Clemens Bos, Lambertus Bartels, Martijn Boomsma, Derk Slotman, Erik Phernambucq, Ingrid Nijholt, Alessio Morganti, Giambattista Siepe, Milly Buwenge, Holger Gruell, Grischa Bratke, Sin Yuin Yeo, Roberto Blanco, Heikki Minn, Mira Huhtala, Alessandro Napoli, Francesca de Felice, Carlo Catalano, Alberto Bazzocchi, Chiara Gasperini, Laura Campanacci, Julia Galendi, Dirk M
Published in: Clin Transl Radiat Oncol, 2022, ISSN 2693-5015
Publisher: Elsevier
DOI: 10.21203/rs.3.rs-823194/v1

High-Intensity Focused Ultrasound Surgery for Tumor Ablation: A Review of Current Applications

Author(s): Alessandro De Maio, Giulia Alfieri, Monica Mattone, Pejman Ghanouni, Alessandro Napoli
Published in: Radiology: Imaging Cancer, Issue 6, 2023, ISSN 2638-616X
Publisher: Radiological Society of North America (RSNA)
DOI: 10.1148/rycan.230074

Focused Ultrasound and External Beam Radiation Therapy for Painful Bone Metastases: A Phase II Clinical Trial

Author(s): Alessandro Napoli, Alessandro De Maio, Giulia Alfieri, Chiara Gasperini, Roberto Scipione, Laura Campanacci, Giambattista Siepe, Francesca De Felice, Benedetta Siniscalchi, Lorenzo Chiurchioni, Vincenzo Tombolini, Davide Maria Donati, Alessio Giuseppe Morganti, Pejman Ghanouni, Carlo Catalano, Alberto Bazzocchi
Published in: Radiology, Issue 307, 2023, ISSN 0033-8419
Publisher: Radiological Society of North America
DOI: 10.1148/radiol.211857

Musculoskeletal oncology and thermal ablation: the current and emerging role of interventional radiology

Author(s): Alberto Bazzocchi, Maria Pilar Aparisi Gómez, Makoto Taninokuchi Tomassoni, Alessandro Napoli, Dimitrios Filippiadis, Giuseppe Guglielmi
Published in: Skeletal Radiology, Issue 52, 2023, Page(s) 447-459, ISSN 0364-2348
Publisher: Springer Verlag
DOI: 10.1007/s00256-022-04213-3

A time-driven activity-based costing approach of magnetic resonance-guided high-intensity focused ultrasound for cancer-induced bone pain

Author(s): Julia Simões Corrêa Galendi, Sin Yuin Yeo, Dusan Simic, Holger Grüll, Stephanie Stock & Dirk Müller
Published in: International Journal of Hyperthermia, 2022, Page(s) 173-180, ISSN 0265-6736
Publisher: Taylor & Francis
DOI: 10.1080/02656736.2021.2023768

Combining radiotherapy and focused ultrasound for pain palliation of cancer induced bone pain; a stage I/IIa study according to the IDEAL framework

Author(s): Marcia M.T.J. Bartels, Inez M. Verpalen, Cyril J. Ferrer, Derk J. Slotman, Erik C.J. Phernambucq, Joost J.C. Verhoeff, Wietse S.C. Eppinga, Manon N.G.J.A. Braat, Rolf D. van den Hoed, Miranda van 't Veer-Ten Kate, Erwin de Boer, Harry R. Naber, Ingrid M. Nijholt, Lambertus W. Bartels, Clemens Bos, Chrit T.W. Moonen, Martijn F. Boomsma, Helena M. Verkooijen
Published in: Clinical and Translational Radiation Oncology, Issue 27, 2025, Page(s) 57-63, ISSN 2405-6308
Publisher: Elsevier BV
DOI: 10.1016/j.ctro.2021.01.005

Pain response of patients treated with radiotherapy for painful bone metastases between 2013 and 2024 – An analysis of the prospective real-world PRESENT cohort

Author(s): R. Hovenier, E.H. Huele, B.J.J. Bindels, A. van Oss, R.H. Kuijten, J.J. Verlaan, N. Kasperts, W.S.C. Eppinga, Y.M. van der Linden, H.M. Verkooijen, R. Gal, J.M. van der Velden
Published in: Radiotherapy and Oncology, Issue 214, 2026, Page(s) 111263, ISSN 0167-8140
Publisher: Elsevier BV
DOI: 10.1016/j.radonc.2025.111263

Synthetic CT for the planning of MR-HIFU treatment of bone metastases in pelvic and femoral bones: a feasibility study

Author(s): Beatrice Lena, Mateusz C. Florkow, Cyril J. Ferrer, Marijn van Stralen, Peter R. Seevinck, Evert-Jan P. A. Vonken, Martijn F. Boomsma, Derk J. Slotman, Max A. Viergever, Chrit T. W. Moonen, Clemens Bos, Lambertus W. Bartels
Published in: European Radiology, Issue 32, 2022, Page(s) 4537-4546, ISSN 1432-1084
Publisher: Springer Science and Business Media LLC
DOI: 10.1007/s00330-022-08568-y

Further Clarification of Pain Management Complexity in Radiotherapy: Insights from Modern Statistical Approaches

Author(s): Costanza Maria Donati, Erika Galietta, Francesco Cellini, Alessia Di Rito, Maurizio Portaluri, Cristina De Tommaso, Anna Santacaterina, Consuelo Tamburella, Filippo Mammini, Rossella Di Franco, Salvatore Parisi, Sabrina Cossa, Antonella Bianculli, Pierpaolo Ziccarelli, Luigi Ziccarelli, Domenico Genovesi, Luciana Caravatta, Francesco Deodato, Gabriella Macchia, Francesco Fiorica, Giuseppe Napoli,
Published in: Cancers, Issue 16, 2025, Page(s) 1407, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers16071407

Interrater Agreement in Assessment of Eligibility for Magnetic Resonance–Guided High-Intensity Focused Ultrasound of Patients with Painful Bone Metastases

Author(s): Renée Hovenier, Clemens Bos, Martijn F. Boomsma, Holger Grüll, Alessio G. Morganti, Helena M. Verkooijen
Published in: Journal of Vascular and Interventional Radiology, Issue 36, 2025, Page(s) 917-921.e4, ISSN 1051-0443
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.jvir.2025.01.025

Factors Influencing the Adoption of Magnetic Resonance-Guided High-Intensity Focused Ultrasound for Painful Bone Metastases in Europe, A Group Concept Mapping Study

Author(s): Julia Simões Corrêa Galendi, Ann-Cathrine Siefen, Debora M. Moretti, Sin Yuin Yeo, Holger Grüll, Grischa Bratke, Alessio Giuseppe Morganti, Alberto Bazzocchi, Chiara Gasperini, Francesca De Felice, Roberto Blanco Sequeiros, Mira Huhtala, Ingrid M. Nijholt, Martijn F. Boomsma, Clemens Bos, Helena M. Verkooijen, Dirk Müller, Stephanie Stock
Published in: International Journal of Environmental Research and Public Health, Issue 20, 2024, Page(s) 1084, ISSN 1660-4601
Publisher: MDPI
DOI: 10.3390/ijerph20021084

Musculoskeletal Oncologic Interventions: Proceedings from the Society of Interventional Radiology and Society of Interventional Oncology Research Consensus Panel

Author(s): Anil Nicholas Kurup, Jack W. Jennings, Sean Tutton, Alda L. Tam, Alexis Kelekis, Bradford J. Wood, Damian E. Dupuy, Alessandro Napoli, Sean S. Park, Steven I. Robinson, Peter S. Rose, Michael C. Soulen, Sarah B. White, Matthew R. Callstrom
Published in: Journal of Vascular and Interventional Radiology, Issue 32, 2025, Page(s) 1089.e1-1089.e9, ISSN 1051-0443
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1016/j.jvir.2021.04.008

High Intensity Focused Ultrasound for Treatment of Bone Malignancies—20 Years of History

Author(s): Sin Yuin Yeo, Grischa Bratke, Holger Grüll
Published in: Cancers, Issue 15, 2025, Page(s) 108, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15010108

MRI-Guided Focused Ultrasound of Osseous Metastases

Author(s): Rachel R. Bitton, Jarrett Rosenberg, Suzanne LeBlang, Alessandro Napoli, Joshua Meyer, Kim Butts Pauly, Mark Hurwitz, Pejman Ghanouni
Published in: Investigative Radiology, Issue 56, 2025, Page(s) 141-146, ISSN 0020-9996
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/rli.0000000000000721

Eligibility for Magnetic Resonance‐Guided High Intensity Focused Ultrasound in Patients Referred for Radiotherapy on Painful Nonspinal Bone Metastases

Author(s): Renée Hovenier, Derk J. Slotman, Chiara Gasperini, Alice Zamagni, Mira Huhtala, Manon N. G. J. A. Braat, Wietse S. C. Eppinga, Nicolien Kasperts, Erik C. J. Phernambucq, Martijn F. Boomsma, Ingrid M. Nijholt, Roberto Blanco Sequeiros, Alberto Bazzocchi, Alessio G. Morganti, Chrit T. W. Moonen, Clemens Bos, Helena M. Verkooijen, null null
Published in: International Journal of Clinical Practice, Issue 2025, 2026, ISSN 1368-5031
Publisher: Medicom International, Inc.
DOI: 10.1155/ijcp/4962457