Project description
Innovative platform to translate connectome Big Data for neurodiagnostics
The nervous system of an organism contains neurons that communicate through synapses. A connectome is a comprehensive wiring map of neural connections in the brain. The clinical utilisation of connectomes is limited, and neurologists mostly rely on subjective analysis of brain scans. NeuroXM was developed as the first commercial application to translate connectome Big Data into clinically relevant information to improve neurodiagnosis. The EU-funded BrainBase project aims to assess the feasibility of different potential clinical applications of NeuroXM, using it in combination with patients’ clinical data. The ultimate goal is to develop the market strategy that will establish the platform as a significant neurodiagnostic tool.
Objective
The connectome is a map of all neural connections in the brain that can provide information about the brain’s (re)wiring in neurological diseases, injuries, or drugs responses. The use of connectomes in clinical practice has enormous potential to improve treatment efficacy, enhance patient stratification, disease characterization, and ultimately diagnosis. However, the means to clinically utilize connectomes are limited. Therefore neurologists still rely on subjective analysis of brain scans. Although the use of big data tools in neuro-diagnostics is growing, no commercial application for clinical practice is available yet.
Biomax developed the first commercial solution to translate big connectome data into clinically relevant information: NeuroXM. In combination with patients’ clinical data this can be valorized to improve neuro-diagnosis. NeuroXM has successfully undergone pilot studies at two major institutes. The proprietary NeuroXM platform includes all features and security levels that are required in the clinic. Biomax is a strong bioinformatic SME with 20 years’ experience, including >25 European grants, 5 successful bioinformatic products, and a pioneering reputation.
NeuroXM targets a very large and diverse neurology market with multiple clinical applications, e.g. diagnosis of dementia using brain imaging, detecting brain wiring “disconnections” in schizophrenia, and establishing treatment efficacy (longitudinal assessments of the connectome). This SME Phase 1 project will assess the feasibility of these different applications, which will help Biomax to establish a Go/No-go for further clinical validation for the specific clinical applications. With a strong first mover advantage and freedom to operate, NeuroXM has the potential to become the gold standard for working with connectome data. Commercialization of NeuroXM will provide Biomax a cumulative revenue of €47,4 million (2025) and further company growth.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences data science big data
- medical and health sciences basic medicine neurology neurodegenerative diseases dementia
- medical and health sciences clinical medicine psychiatry schizophrenia
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.3. - PRIORITY 'Societal challenges
See all projects funded under this programme -
H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
82152 STEINKIRCHEN
Germany
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.