Project description
Microfluidics technology enters industrial bioprocessing
A bioreactor is an apparatus designed to culture cells under controlled conditions offering a continuous supply of nutrients and gases and removing waste and metabolites. This system is used in industrial processes for the production of pharmaceuticals, vaccines, cosmetics or nutritional supplements. However, the technology for the harvesting of cells is inefficient, necessitating a more high-throughput process. To address this need, the EU-funded HuBMBLES project proposes to advance microfluidics technology to industrial scale. The generated microfluidic arrays will be tested for the harvesting of microbial cell cultures to enable sustainable and more energy-efficient production.
Objective
It is widely reported all over the world that primary recovery of cells from bioreactor systems are currently underserved by the existing technologies of filtration, flocculation and centrifugation. This is due to both the volumes of liquid required for economical production and the number of cells or particles suspended in them. Where these biological cells can produce an enormous range of products such as medicine, food, cosmetics, pigments, nutritional supplements, plastics and fuel; the industries active with this sustainable method of production are burdened by stagnant and inefficient technologies for the harvesting of these cells. We, uFraction8 Limited, have developed a technology 'HuMBLES' designed to address this need for a scalable, low energy primary recovery solution. Using massively multiplexed modular microfluidic arrays,HuMBLES is readily scalable to address the needs of bioprocessing industry. Leveraging the ability to scale microfluidics throughput out of the lab and into industry promises, this Phase 1 project is focused at exploring the techno-economic feasibility of using multiplexed microfluidic arrays to for harvesting of microbial cell cultures to enable sustainable bioproduction. Successful development and commercialisation of HuMBLES will enable the economic production of goods using sustainable cell based manufacture, hence transforming industry to the great benefit of the environment.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences classical mechanics fluid mechanics microfluidics
- engineering and technology environmental biotechnology bioremediation bioreactors
- engineering and technology industrial biotechnology bioprocessing technologies
- engineering and technology environmental engineering energy and fuels
- engineering and technology environmental engineering waste management waste treatment processes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-1 - SME instrument phase 1
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
FK1 1LL FALKIRK
United Kingdom
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.