BRInGing nano-pHoTonics into the brain

Información del proyecto

NanoBRIGHT

Identificador del acuerdo de subvención: 828972

DOI

10.3030/828972

Proyecto cerrado

Fecha de la firma de la CE 17 Diciembre 2018

Fecha de inicio 1 Mayo 2019

Fecha de finalización 30 Abril 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Coste total

€ 3 496 197,50

Aportación de la UE

€ 3 496 197,50

Coordinado por

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Italy

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (3)

Communication material

Communication materials including visual identity and basic project rules for communication

Design of the plasmonic structures

Geometric design of metallic structures realized on the tapered fibers Results of simulations will be reported in terms of electromagnetic field distribution reflectance and transmission spectrum Two different types of plasmonic structures will be designed one that maximizes scattering and one that maximizes absorption for SERS and heat generation respectively

Implementation of the M-2PL System

A M2PL system will be implemented as described in Task 31 able to perform twophoton lithography along the entire taper We will report the design of the system in terms of optical path its spatial resolution and its writing speed

Websites, patent fillings, videos etc. (1)

Project website and logo

The project website is online and the project logo is created The project website will be continuously updated during the project

Publicaciones

Peer reviewed articles (31)

Wavefront engineering for controlled structuring of far-field intensity and phase patterns from multimodal optical fibers

Autores: Liam Collard, Filippo Pisano, Marco Pisanello, Antonio Balena, Massimo De Vittorio, Ferruccio Pisanello
Publicado en: APL Photonics, Edición 6/5, 2021, Página(s) 051301, ISSN 2378-0967
Editor: AIP
DOI: 10.1063/5.0044666

Unwrapping non-locality in the image transmission through turbid media

Autores: Mohammadrahim Kazemzadeh, Liam Collard, Filippo Pisano, Linda Piscopo, Cristian Ciraci, Massimo De Vittorio, and Ferruccio Pisanello
Publicado en: optics express, Edición 32, 2024, Página(s) 26414, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.521581

Holographic Manipulation of Nanostructured Fiber Optics Enables Spatially‐Resolved, Reconfigurable Optical Control of Plasmonic Local Field Enhancement and SERS

Autores: Collard, Liam; Pisano, Filippo; Zheng, Di; Balena, Antonio; Kashif, Muhammad Fayyaz; Pisanello, Marco; D'Orazio, Antonella; De La Prida, Liset M; Ciracì, Cristian; Grande, Marco; De Vittorio, Massimo; Pisanello, Ferruccio
Publicado en: Small, Edición 14, 2022, ISSN 1613-6829
Editor: Whiley
DOI: 10.1002/smll.202200975

Comparative study of autofluorescence in flat and tapered optical fibers towards application in depth-resolved fluorescence lifetime photometry in brain tissue

Autores: Marco Bianco, Antonio Balena, Marco Pisanello, Filippo Pisano, Leonardo Sileo, Barbara Spagnolo, Cinzia Montinaro, Bernardo L. Sabatini, Massimo De Vittorio, Ferruccio Pisanello
Publicado en: Biomedical Optics Express, Edición 12/2, 2021, Página(s) 993, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/boe.410244

Recent Advances on High-Speed and Holographic Two-Photon Direct Laser Writing

Autores: Antonio Balena, Marco Bianco, Ferruccio Pisanello, Massimo De Vittorio
Publicado en: Advanced Functional Materials, 2023, ISSN 1616-3028
Editor: Whiley
DOI: 10.1002/adfm.202211773

Influence of the anatomical features of different brain regions on the spatial localization of fiber photometry signals

Autores: Cinzia Montinaro, Marco Pisanello, Marco Bianco, Barbara Spagnolo, Filippo Pisano, Antonio Balena, Francesco De Nuccio, Dario Domenico Lofrumento, Tiziano Verri, Massimo De Vittorio, Ferruccio Pisanello
Publicado en: Biomedical Optics Express, Edición 12/10, 2021, Página(s) 6081, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/boe.439848

Ray tracing models for estimating light collection properties of microstructured tapered optical fibers for optical neural interfaces

Autores: Emanuela Maglie, Marco Pisanello, Filippo Pisano, Antonio Balena, Marco Bianco, Barbara Spagnolo, Leonardo Sileo, Bernardo L. Sabatini, Massimo De Vittorio, Ferruccio Pisanello
Publicado en: Optics Letters, Edición 45/14, 2020, Página(s) 3856, ISSN 0146-9592
Editor: Optical Society of America
DOI: 10.1364/ol.397022

Brain Microenvironment Heterogeneity: Potential Value for Brain Tumors

Autores: Laura Álvaro-Espinosa, Ana de Pablos-Aragoneses, Manuel Valiente, Neibla Priego
Publicado en: Frontiers in Oncology, Edición 11, 2021, ISSN 2234-943X
Editor: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.714428

Numerical calculation of the light propagation in tapered optical fibers for optical neural interfaces

Autores: Rosa Mach Batlle, Marco Pisanello, Filippo Pisano, Massimo De Vittorio, Ferruccio Pisanello, Cristian Ciraci
Publicado en: Journal of Lightwave Technology, 2021, Página(s) 1-1, ISSN 0733-8724
Editor: Optical Society of America
DOI: 10.1109/jlt.2021.3118898

Exploiting holographically encoded variance to transmit labelled images through a multimode optical fiber

Autores: Collard, Liam; Kazemzadeh, Mohammadrahim; Piscopo, Linda; De Vittorio, Massimo; Pisanello, Ferruccio
Publicado en: Optics Express, Edición 32, 2024, Página(s) 18896, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.519379

Roadmap on perovskite nanophotonics

Autores: Soci C.; Adamo G.; Cortecchia D.; Wang K.; Xiao S.; Song Q.; Schall-Giesecke A.L.; Cegielski P.J.; Lemme M.C.; Gerace D.; Sanvitto D.; Tian J.; Tonkaev P.A.; Makarov S.V.; Kivshar Y.S.; Jimenez Gordillo O.A.; Melloni A.; Pushkarev A.P.; D'Amato M.; Lhuillier E.; Bramati A.
Publicado en: Optical Materials X, 2022, ISSN 2590-1478
Editor: Elsevier
DOI: 10.1016/j.omx.2022.100214

Advantages of internal reference in holographic shaping ps supercontinuum pulses through multimode optical fibers

Autores: Linda Piscopo, Liam Collard, Filippo Pisano, Antonio Balena, Massimo De Vittorio, and Ferruccio Pisanello
Publicado en: Optics Express, Edición 32, 2024, Página(s) 24144, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.528043

A clinically-compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis

Autores: Zhu L, Retana D, García-Gómez P, Alvaro-Espinosa L, Priego N, Masmudi-Martín M, Yebra N, Miarka L, Hernández-Encinas E, Blanco-Aparicio C, Martínez S, Sobrino C, Ajenjo N, Artiga MJ, Ortega-Paino E, Torres-Ruiz R, Rodríguez-Perales S, RENACER, Soffietti R, Bertero L, Cassoni P, Weiss T, Muñoz J, Sepúlveda JM, González-León P, Jiménez-Roldán L, Moreno LM, Esteban O, Pérez-Núñez A, H
Publicado en: EMBO Molecular Medicine, 2022, ISSN 1757-4676
Editor: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202114552

Two-photon fluorescence-assisted laser ablation of non-planar metal surfaces: fabrication of optical apertures on tapered fibers for optical neural interfaces

Autores: Antonio Balena, Marco Bianco, Filippo Pisano, Marco Pisanello, Leonardo Sileo, Bernardo L. Sabatini, Massimo De Vittorio, Ferruccio Pisanello
Publicado en: Optics Express, Edición 28/15, 2020, Página(s) 21368, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.395187

Highly Photostable Perovskite Nanocubes: Toward Integrated Single Photon Sources Based on Tapered Nanofibers

Autores: Stefano Pierini, Marianna D’Amato, Mayank Goyal, Quentin Glorieux, Elisabeth Giacobino, Emmanuel Lhuillier, Christophe Couteau, Alberto Bramati
Publicado en: ACS Photonics, Edición 7/8, 2020, Página(s) 2265-2272, ISSN 2330-4022
Editor: American Chemical Society
DOI: 10.1021/acsphotonics.0c00820

Implantable photonic nano-modulators open perspectives for advanced optical interfaces with deep brain areas

Autores: Ferruccio Pisanello, Massimo De Vittorio, Filippo Pisano
Publicado en: Neurophotonics, Edición 11, 2024, Página(s) S11512, ISSN 2329-423X
Editor: SPIE
DOI: 10.1117/1.nph.11.s1.s11512

The Potential of Astrocytes as Immune Modulators in Brain Tumors

Autores: Neibla Priego, Manuel Valiente
Publicado en: Frontiers in Immunology, Edición 10, 2019, ISSN 1664-3224
Editor: Frontiers in
DOI: 10.3389/fimmu.2019.01314

Nanofiber based displacement sensor

Autores: Chengjie Ding, Maxime Joos, Constanze Bach, Tom Bienaimé, Elisabeth Giacobino, E Wu, Alberto Bramati, Quentin Glorieux
Publicado en: Applied Physics B, Edición 126/6, 2020, ISSN 0946-2171
Editor: Springer Verlag
DOI: 10.1007/s00340-020-07452-1

Single-cell micro- and nano-photonic technologies

Autores: Filippo Pisano, Marco Pisanello, Massimo De Vittorio, Ferruccio Pisanello
Publicado en: Journal of Neuroscience Methods, Edición 325, 2019, Página(s) 108355, ISSN 0165-0270
Editor: Elsevier BV
DOI: 10.1016/j.jneumeth.2019.108355

Protocol to generate murine organotypic brain cultures for drug screening and evaluation of anti-metastatic efficacy

Autores: Lucía Zhu, Lauritz Miarka, Patricia Baena, María Perea-García, Manuel Valiente
Publicado en: STAR Protocols, 2023, ISSN 2666-1667
Editor: Cell Press
DOI: 10.1016/j.xpro.2023.102194

Neurophotonic tools for microscopic measurements and manipulation: status report.

Autores: Ahmed Abdelfattah; Srinivasa Rao Allu; Robert E. Campbell; Xiaojun Cheng; Tomáš Cižmár; Irene Costantini; Valentina Emiliani; Natalie Fomin-Thunemann; Ariel Gilad; Tomás Fernández Alfonso; Christopher G. L. Ferri; Andrew Harris; Elizabeth M. C. Hillman; Matthew G. Holt; Kivilcim Kiliç; Evan W. Miller; Rickson C. Mesquita; K.M. Naga Srinivas Nadella; U. Valentin Nägerl; Citlali Perez Campos
Publicado en: Neurophotonics, Edición 18, 2022, ISSN 2329-4248
Editor: SPIE

Label-free biomechanical nanosensor based on LSPR for biological applications

Autores: M. Salbini, T. Stomeo, C. Ciracì, R. Fiammengo, V. Mangini, A. Toma, F. Pisano, F. Pisanello, T. Verri, D. R. Smith, M. De Vittorio
Publicado en: Optical Materials Express, Edición 10/5, 2020, Página(s) 1264, ISSN 2159-3930
Editor: Optical Society of America
DOI: 10.1364/ome.385713

Plasmonics on a Neural Implant: Engineering Light–Matter Interactions on the Nonplanar Surface of Tapered Optical Fibers

Autores: Pisano, Filippo; Kashif, Muhammad Fayyaz; Balena, Antonio; Pisanello, Marco; De Angelis, Francesco; Prida, Liset M; Valiente, Manuel; D'Orazio, Antonella; De Vittorio, Massimo; Grande, Marco; Pisanello, Ferruccio
Publicado en: Advanced Optical materials, 2022, ISSN 2195-1071
Editor: Wiley
DOI: 10.1002/adom.202101649

Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits

Autores: Alberto Sanchez-Aguilera,Mariam Masmudi-Martín,Andrea Navas-Olive,Patricia Baena,Carolina Hernández-Oliver,Neibla Priego,Lluís Cordón-Barris,Laura Alvaro-Espinosa,Santiago García,Sonia Martínez,Miguel Lafarga
Publicado en: Cancer Cell, Edición 41, 2023, Página(s) 1637, ISSN 1535-6108
Editor: Cell Press
DOI: 10.1016/j.ccell.2023.07.010

High transmission from 2D periodic plasmonic finite arrays with sub-20 nm gaps realized with Ga focused ion beam milling

Autores: Filippo Pisano, Antonio Balena, Muhammad Fayyaz Kashif, Marco Pisanello, Gaia de Marzo, Luciana Algieri, Antonio Qualtieri, Leonardo Sileo, Tiziana Stomeo, Antonella D’Orazio, Massimo De Vittorio, Ferruccio Pisanello, Marco Grande
Publicado en: Nanotechnology, Edición 31/43, 2020, Página(s) 435301, ISSN 0957-4484
Editor: Institute of Physics Publishing
DOI: 10.1088/1361-6528/aba57a

Tapered fibertrodes for optoelectrical neural interfacing in small brain volumes with reduced artefacts

Autores: Spagnolo, Barbara; Balena, Antonio; Peixoto, Rui T.; Pisanello, Marco; Sileo, Leonardo; Bianco, Marco; Rizzo, Alessandro; Pisano, Filippo; Qualtieri, Antonio; Lofrumento, Dario Domenico; De Nuccio, Francesco; Assad, John A.; Sabatini, Bernardo L.; De Vittorio, Massimo; Pisanello, Ferruccio
Publicado en: Nature Materials, Edición 16, 2022, ISSN 1476-1122
Editor: Nature Publishing Group
DOI: 10.1038/s41563-022-01272-8

Toward Plasmonic Neural Probes: SERS Detection of Neurotransmitters through Gold-Nanoislands-Decorated Tapered Optical Fibers with Sub-10 nm Gaps

Autores: Di Zheng, Filippo Pisano, Liam Collard, Antonio Balena, Marco Pisanello, Barbara Spagnolo, Rosa Mach-Batlle, Francesco Tantussi, Luigi Carbone, Francesco De Angelis, Manuel Valiente, Liset M. de la Prida, Cristian Ciracì, Massimo De Vittorio, Ferruccio Pisanello
Publicado en: Advanced Materials, 2023, ISSN 1521-4095
Editor: Wiley
DOI: 10.1002/adma.202200902

An open source three-mirror laser scanning holographic two-photon lithography system

Autores: Pisanello, Marco; Zheng, Di; Balena, Antonio; Pisano, Filippo; De Vittorio, Massimo; Pisanello, Ferruccio
Publicado en: Plos One, Edición 16, 2022, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0265678

Highly Photostable Zn-Treated Halide Perovskite Nanocrystals for Efficient Single Photon Generation

Autores: Marianna D’Amato; Lucien Belzane; Corentin Dabard; Mathieu Silly; Gilles Patriarche; Quentin Glorieux; Hanna Le Jeannic; Emmanuel Lhuillier; Alberto Bramati
Publicado en: Nano Letters, 2023, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.3c02739

Orthogonalization of far-field detection in tapered optical fibers for depth-selective fiber photometry in brain tissue

Autores: Marco Bianco, Marco Pisanello, Antonio Balena, Cinzia Montinaro, Filippo Pisano, Barbara Spagnolo, Bernardo L. Sabatini; Massimo De Vittorio; Ferruccio Pisanello
Publicado en: APL Photonics, 2022, ISSN 2378-0967
Editor: AIP Publishing
DOI: 10.1063/5.0073594

Color-Tunable Mixed-Cation Perovskite Single Photon Emitters

Autores: Marianna D’Amato, Qi Ying Tan, Quentin Glorieux, Alberto Bramati, and Cesare Soci
Publicado en: ACS Photonics, 2023, ISSN 2330-4022
Editor: American Chemical Society
DOI: 10.1021/acsphotonics.2c01437