Project description DEENESFRITPL Linking exosome genetic cargo and health status The EU-funded MindGAP project is exploring a radical new vision that may bridge the gap between health status and mind/body interactions. Recent studies show that exosomes circulate throughout the body, delivering genetic data to recipient cells as messengers of health and disease, and they are also implicated in brain activity as they can cross the blood–brain barrier. Overall, the project is investigating the relationship between the genetic data in exosomes and health status as well as the possible link with mind-related activities. The goal is to create an innovative tool to analyse exosome genetic data, allowing each individual to correlate this information with their health status. The project will also explore meditation as a mental tool to control the health-related exosome cargo. Show the project objective Hide the project objective Objective MindGAP presents a radical new vision that may BRIDGE the GAP between HEALTH status and MIND/BODY interactions and lead to a paradigm shift in medicine. The disruptive idea presented herein is sustained by relevant data presented in the literature: (i) exosomes circulate throughout the body as messengers of health and disease, transporting genetic data to be delivered into a recipient cell; (ii) and exosomes are implicated in brain activity, having the ability to cross the blood brain barrier. Thus, when exosomes circulate and exit the brain to peripheral cells, there is a message transported therein, which is related to its cargo inside the vesicle. Overall, we aim to know which cargo is related to health and which cargo is related to disease. Traditionally, everyone has been looking for disease indicators to detect disease. Herein, we look for sensitive health indicators that may change under disease installation, therefore yielding an unprecedented early disease detection possibility. Moreover, the possibility of using MINDFULNESS meditation as a mind-related tool to control the cargo of exosomes is explored herein. If meditation is successful in changing the behaviour and attitudes of many people, fighting depression, etc., it means that the exosomes cargo may be changed through this process. Thus, this could be a major route to a self-healing approach before disease begins. Finally, all this knowledge opens doors to an innovative device that may be used by everyone to understand his/her health status. Overall, MindGAP targets (i) the missing relation between the genetic data in EXOSOMES and health status; (ii) interfacing this link with MIND-related activities; (iii) and to create an INNOVATIVE and PORTABLE DEVICE that TRACKS EXOSOMES and ANALYSIS their relevant genetic data, thereby allowing each individual to correlate this information with their own HEALTH STATUS and the installation of a pro-active attitude of each one of us against disease. Fields of science natural sciencesbiological sciencescell biology Keywords Mind and body interaction Extracellular vesicles Plastic antibodies Bio-monitoring personalized medicine Programme(s) H2020-EU.1.2. - EXCELLENT SCIENCE - Future and Emerging Technologies (FET) Main Programme H2020-EU.1.2.1. - FET Open Topic(s) FETOPEN-01-2018-2019-2020 - FET-Open Challenging Current Thinking Call for proposal H2020-FETOPEN-2018-2020 See other projects for this call Sub call H2020-FETOPEN-2018-2019-2020-01 Funding Scheme RIA - Research and Innovation action Coordinator UNIVERSIDADE DE COIMBRA Net EU contribution € 1 105 191,66 Address Paco das escolas 3004-531 Coimbra Portugal See on map Region Continente Centro (PT) Região de Coimbra Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (5) Sort alphabetically Sort by Net EU contribution Expand all Collapse all OULUN YLIOPISTO Finland Net EU contribution € 866 656,25 Address Pentti kaiteran katu 1 90014 Oulu See on map Region Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Pohjanmaa Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TEKNOLOGIAN TUTKIMUSKESKUS VTT OY Finland Net EU contribution € 826 342,50 Address Tekniikantie 21 02150 Espoo See on map Region Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTITUTO PORTUGUES DE ONCOLOGIA DO PORTO FRANCISCO GENTIL, EPE Portugal Net EU contribution € 793 525,00 Address Rua antonio bernardino almeida 4200-072 Porto See on map Region Continente Norte Área Metropolitana do Porto Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 LINNEUNIVERSITETET Sweden Net EU contribution € 789 375,00 Address Linnaeus university 35195 Vaxjo See on map Region Södra Sverige Småland med öarna Kronobergs län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTITUTO SUPERIOR DE ENGENHARIA DO PORTO Participation ended Portugal Net EU contribution € 54 739,59 Address Rua dr antonio bernardino de almeida 431 4200-072 Porto See on map Region Continente Norte Área Metropolitana do Porto Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00