Descripción del proyecto
Vincular la carga genética de los exosomas y el estado de salud
El proyecto financiado con fondos europeos MindGAP estudia una nueva visión radical que podría acortar la brecha entre el estado de salud y las interacciones entre la mente y el cuerpo. Estudios recientes muestran que los exosomas circulan por el cuerpo llevando datos genéticos a células receptoras como unos mensajeros de la salud y la enfermedad, y que también están implicados en la actividad encefálica, ya que pueden cruzar la barrera hematoencefálica. En conjunto, el proyecto está investigando la relación entre los datos genéticos en los exosomas y el estado de salud, así como el posible vínculo con actividades relacionadas con la mente. El objetivo es crear una herramienta innovadora para analizar los datos genéticos de los exosomas y permitir a cada individuo relacionar esta información con su estado de salud. El proyecto también estudiará la meditación como herramienta mental para controlar la carga exosómica relacionada con la salud.
Objetivo
MindGAP presents a radical new vision that may BRIDGE the GAP between HEALTH status and MIND/BODY interactions and lead to a paradigm shift in medicine. The disruptive idea presented herein is sustained by relevant data presented in the literature: (i) exosomes circulate throughout the body as messengers of health and disease, transporting genetic data to be delivered into a recipient cell; (ii) and exosomes are implicated in brain activity, having the ability to cross the blood brain barrier. Thus, when exosomes circulate and exit the brain to peripheral cells, there is a message transported therein, which is related to its cargo inside the vesicle. Overall, we aim to know which cargo is related to health and which cargo is related to disease. Traditionally, everyone has been looking for disease indicators to detect disease. Herein, we look for sensitive health indicators that may change under disease installation, therefore yielding an unprecedented early disease detection possibility. Moreover, the possibility of using MINDFULNESS meditation as a mind-related tool to control the cargo of exosomes is explored herein. If meditation is successful in changing the behaviour and attitudes of many people, fighting depression, etc., it means that the exosomes cargo may be changed through this process. Thus, this could be a major route to a self-healing approach before disease begins. Finally, all this knowledge opens doors to an innovative device that may be used by everyone to understand his/her health status. Overall, MindGAP targets (i) the missing relation between the genetic data in EXOSOMES and health status; (ii) interfacing this link with MIND-related activities; (iii) and to create an INNOVATIVE and PORTABLE DEVICE that TRACKS EXOSOMES and ANALYSIS their relevant genetic data, thereby allowing each individual to correlate this information with their own HEALTH STATUS and the installation of a pro-active attitude of each one of us against disease.
Ámbito científico
Palabras clave
Programa(s)
Convocatoria de propuestas
Consulte otros proyectos de esta convocatoriaConvocatoria de subcontratación
H2020-FETOPEN-2018-2019-2020-01
Régimen de financiación
RIA - Research and Innovation actionCoordinador
3004-531 Coimbra
Portugal