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Next generation precision antibody profiling - from science fiction to reality

Project description

Antibody sequencing opens new opportunities in medical research

The antibody repertoire in the adaptive human immune system evolved to tackle the great number of pathogens (bacteria, viruses) and exogenous threats (toxins). Understanding which antibodies are produced in response to a particular pathogen can pave the way towards more efficient and personalised therapies. To address this issue, the EU-funded TopSpec project has developed an improved platform based on mass spectrometry for the sequencing of antibodies. Alongside a high-performance data acquisition system and data processing and analysis software, TopSpec will significantly increase the opportunities in medical research and drug development and expand our knowledge of the immune system.

Call for proposal

H2020-FETOPEN-2018-2020

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Sub call

H2020-FETOPEN-2018-2019-2020-01

Coordinator

KAROLINSKA INSTITUTET
Net EU contribution
€ 989 500,00
Address
Nobels Vag 5
17177 Stockholm
Sweden

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (7)

FASMATECH EPISTIMONIKI KAI TECHNOLOGIKI ANONYMI ETAIREIA
Greece
Net EU contribution
€ 860 500,00
Address
Patriarchou Grigoriou E Kai Neapoleos, Lefkippos Technology Park, Ncsr Demokritos, Building 27
153 41 Agia Paraskevi

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Αττική Aττική Βόρειος Τομέας Αθηνών
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
THERMO FISHER SCIENTIFIC (BREMEN) GMBH
Germany
Net EU contribution
€ 695 500,00
Address
Hanna Kunath Strasse 11
28199 Bremen

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Region
Bremen Bremen Bremen, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
SPECTROSWISS SARL
Switzerland
Net EU contribution
€ 430 500,00
Address
Epfl Innovation Park Building I
1015 Lausanne

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
BIOMOTIF AB
Sweden
Net EU contribution
€ 325 000,00
Address
Wanning Kometvagen 17
18348 Stockholm

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Östra Sverige Stockholm Stockholms län
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
THE NOTTINGHAM TRENT UNIVERSITY
United Kingdom
Net EU contribution
€ 306 500,00
Address
50 Shakespeare Street
NG1 4FQ Nottingham

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Region
East Midlands (England) Derbyshire and Nottinghamshire Nottingham
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
INSTITUT PASTEUR
France
Net EU contribution
€ 278 500,00
Address
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Other funding
€ 0,00
SPECTROMETRY VISION BV
Netherlands
Net EU contribution
€ 105 500,00
Address
Televisieweg 40
1322 AM Almere

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Oost-Nederland Flevoland Flevoland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00