Hydrogen Bonding Phase Transfer Catalysis

Project Information

HBPTC

Grant agreement ID: 832994

DOI

10.3030/832994

Project closed

EC signature date 23 April 2019

Start date 1 July 2019

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 499 070,00

EU contribution

€ 2 499 070,00

Coordinated by

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (14)

Contemporary synthetic strategies in organofluorine chemistry

Author(s): Robert Britton, Veronique Gouverneur, Jin-Hong Lin, Michael Meanwell, Chuanfa Ni, Gabriele Pupo, Ji-Chang Xiao, Jinbo Hu
Published in: Nature Reviews Methods Primers, Issue 1, 2023, ISSN 2662-8449
Publisher: Springer Nature
DOI: 10.1038/s43586-021-00042-1

Enantioconvergent nucleophilic substitution via synergistic phase-transfer catalysis

Author(s): Claire Dooley, Francesco Ibba, Bence B. Botlik, Chiara Palladino, Christopher A. Goult, Yuan Gao, Andrew Lister, Robert S. Paton, Guy C. Lloyd-Jones, Véronique Gouverneur
Published in: Nature Catalysis, Issue 8, 2025, Page(s) 107-115, ISSN 2520-1158
Publisher: Springer Nature
DOI: 10.1038/s41929-024-01288-0

<i>In My Element</i>: Fluorine

Author(s): Véronique Gouverneur
Published in: Chemistry – A European Journal, Issue 25, 2023, Page(s) 7958-7959, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201902265

Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ-Fluoroamines

Author(s): Giulia Roagna, David M. H. Ascough, Francesco Ibba, Anna Chiara Vicini, Alberto Fontana, Kirsten E. Christensen, Aldo Peschiulli, Daniel Oehlrich, Antonio Misale, Andrés A. Trabanco, Robert S. Paton, Gabriele Pupo, Véronique Gouverneur
Published in: Journal of the American Chemical Society, Issue 142/33, 2020, Page(s) 14045-14051, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.0c05131

Impact of Multiple Hydrogen Bonds with Fluoride on Catalysis: Insight from NMR Spectroscopy

Author(s): Francesco Ibba, Gabriele Pupo, Amber L. Thompson, John M. Brown, Timothy D. W. Claridge, Véronique Gouverneur
Published in: Journal of the American Chemical Society, Issue 142/46, 2020, Page(s) 19731-19744, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.0c09832

Hydrogen Bonding Phase-Transfer Catalysis with Alkali Metal Fluorides and Beyond

Author(s): Gabriele Pupo, Véronique Gouverneur
Published in: Journal of the American Chemical Society, Issue 144, 2023, Page(s) 5200-5213, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c00190

Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis

Author(s): Gabriele Pupo, Francesco Ibba, David M. H. Ascough, Anna Chiara Vicini, Paolo Ricci, Kirsten E. Christensen, Lukas Pfeifer, John Richard Morphy, John M. Brown, Robert S. Paton, Véronique Gouverneur
Published in: Science, Issue 360, 2024, Page(s) 638-642, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aar7941

One-Step HF-Free Synthesis of Alkali Metal Fluorides from Fluorspar

Author(s): Thomas Schlatzer, Christopher A. Goult, Michael A. Hayward, Véronique Gouverneur
Published in: Journal of the American Chemical Society, Issue 147, 2025, Page(s) 6338-6342, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.4c16608

Scalable Synthesis of (<i>R</i>,<i>R</i>)-<i>N</i>,<i>N</i>-Dibenzyl-2-fluorocyclohexan-1-amine with CsF under Hydrogen Bonding Phase-Transfer Catalysis

Author(s): Anna Chiara Vicini, Diké-Michel Alozie, Philippe Courtes, Giulia Roagna, Catherine Aubert, Victor Certal, Youssef El-Ahmad, Sébastien Roy, Véronique Gouverneur
Published in: Organic Process Research &amp; Development, Issue 25, 2023, Page(s) 2730-2737, ISSN 1083-6160
Publisher: American Chemical Society
DOI: 10.1021/acs.oprd.1c00312

Fluorspar to fluorochemicals upon low-temperature activation in water

Author(s): Immo Klose, Calum Patel, Anirban Mondal, Andrew Schwarz, Gabriele Pupo, Véronique Gouverneur
Published in: Nature, Issue 635, 2024, Page(s) 359-364, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-024-08125-1

Multigram synthesis of N-alkyl bis-ureas for asymmetric hydrogen bonding phase-transfer catalysis

Author(s): Anna Chiara Vicini, Gabriele Pupo, Francesco Ibba, Véronique Gouverneur
Published in: Nature Protocols, Issue 16, 2021, Page(s) 5559-5591, ISSN 1754-2189
Publisher: Nature Publishing Group
DOI: 10.1038/s41596-021-00625-y

Fluorochemicals from fluorspar via a phosphate-enabled mechanochemical process that bypasses HF

Author(s): Calum Patel, Emy André-Joyaux, Jamie A. Leitch, Xabier Martínez de Irujo-Labalde, Francesco Ibba, Job Struijs, Mathias A. Ellwanger, Robert Paton, Duncan L. Browne, Gabriele Pupo, Simon Aldridge, Michael A. Hayward, Véronique Gouverneur
Published in: Science, Issue 381, 2024, Page(s) 302-306, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.adi1557

Asymmetric Azidation under Hydrogen Bonding Phase-Transfer Catalysis: A Combined Experimental and Computational Study

Author(s): Jimmy Wang, Matthew A. Horwitz, Alexander B. Dürr, Francesco Ibba, Gabriele Pupo, Yuan Gao, Paolo Ricci, Kirsten E. Christensen, Tejas P. Pathak, Timothy D. W. Claridge, Guy C. Lloyd-Jones, Robert S. Paton, Véronique Gouverneur
Published in: Journal of the American Chemical Society, Issue 144, 2023, Page(s) 4572-4584, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.1c13434

Regiodivergent Nucleophilic Fluorination under Hydrogen Bonding Catalysis: A Computational and Experimental Study

Author(s): Matthew A. Horwitz, Alexander B. Dürr, Konstantinos Afratis, Zijun Chen, Julia Soika, Kirsten E. Christensen, Makoto Fushimi, Robert S. Paton, Véronique Gouverneur
Published in: Journal of the American Chemical Society, Issue 145, 2023, Page(s) 9708-9717, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.3c01303