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Mechanistic basis of nucleation and spreading underlying a Polycomb-mediated epigenetic switch

Deliverables

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Publications

The 3′ processing of antisense RNAs physically links to chromatin-based transcriptional control

Author(s): Xiaofeng Fang, Zhe Wu, Oleg Raitskin, Kimberly Webb, Philipp Voigt, Tiancong Lu, Martin Howard, Caroline Dean
Published in: Proceedings of the National Academy of Sciences, 117/26, 2020, Page(s) 15316-15321, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2007268117

The intersection of DNA replication with antisense 3' RNA processing in Arabidopsis FLC chromatin silencing

Author(s): Baxter CL, Šviković S, Sale JE, Dean C, Costa S
Published in: Proceedings of the National Academy of Sciences, Vol. 118 No. 28, 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2107483118

R-loop resolution promotes co-transcriptional chromatin silencing

Author(s): Congyao Xu, Zhe Wu, Hong-Chao Duan, Xiaofeng Fang, Guifang Jia, Caroline Dean
Published in: Nature Communications, 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22083-6

Digital paradigm for Polycomb epigenetic switching and memory

Author(s): Menon G, Schulten A., Dean C., Howard M.
Published in: Current Opinion in Plant Biology, Volume 61, 2021, Page(s) 102012, ISSN 1369-5266
Publisher: Elsevier BV
DOI: 10.1016/j.pbi.2021.102012

Cold-induced Arabidopsis FRIGIDA nuclear condensates for FLC repression

Author(s): Zhu P, Lister, C, Dean C
Published in: Nature, 599, 2021, Page(s) 657-661, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-021-04062-5

Antagonistic cotranscriptional regulation through ARGONAUTE1 and the THO/TREX complex orchestrates FLC transcriptional output

Author(s): Xu C, Fang X, Lu T, Dean C
Published in: Proceedings of the National Academy of Sciences, Vol. 118 No. 47, 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2113757118

VAL1 acts as an assembly platform co-ordinating co-transcriptional repression and chromatin regulation at Arabidopsis FLC.

Author(s): Mikulski P, Wolff P, Lu T, Nielsen M, Zhu D, Franco-Echevarria E, Questa J, Dean C
Published in: bioRxiv preprint, 2021, ISSN 2692-8205
Publisher: bioRxiv
DOI: 10.1101/2021.07.21.453204