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Mechanistic basis of nucleation and spreading underlying a Polycomb-mediated epigenetic switch


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The 3′ processing of antisense RNAs physically links to chromatin-based transcriptional control

Author(s): Xiaofeng Fang, Zhe Wu, Oleg Raitskin, Kimberly Webb, Philipp Voigt, Tiancong Lu, Martin Howard, Caroline Dean
Published in: Proceedings of the National Academy of Sciences, Issue 117/26, 2020, Page(s) 15316-15321, ISSN 0027-8424
DOI: 10.1073/pnas.2007268117

R-loop resolution promotes co-transcriptional chromatin silencing

Author(s): Congyao Xu, Zhe Wu, Hong-Chao Duan, Xiaofeng Fang, Guifang Jia, Caroline Dean
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
DOI: 10.1038/s41467-021-22083-6

Digital paradigm for Polycomb epigenetic switching and memory

Author(s): Menon G, Schulten A., Dean C., Howard M.
Published in: Current Opinion in Plant Biology, Issue Volume 61, 2021, Page(s) 102012, ISSN 1369-5266
DOI: 10.1016/j.pbi.2021.102012