Proteome profiling using plasmonic nanopore sensors

Project Information

NanoProt-ID

Grant agreement ID: 833399

DOI

10.3030/833399

Project closed

EC signature date 19 April 2019

Start date 1 August 2019

End date 31 July 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 498 869,00

EU contribution

€ 2 498 869,00

Coordinated by

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (14)

Over 30-Fold Enhancement in DNA Translocation Dynamics through Nanoscale Pores Coated with an Anionic Surfactant

Author(s): Neeraj Soni; Navneet Chandra Verma; Noam Talor; Amit Meller
Published in: Nano Letters, Issue 23, 2023, Page(s) 4609-4616, ISSN 1530-6984
Publisher: American Chemical Society
DOI: 10.1021/acs.nanolett.3c01096

The emerging landscape of single-molecule protein sequencing technologies

Author(s): Javier Antonio Alfaro, Peggy Bohländer, Mingjie Dai, Mike Filius, Cecil J. Howard, Xander F. van Kooten, Shilo Ohayon, Adam Pomorski, Sonja Schmid, Aleksei Aksimentiev, Eric V. Anslyn, Georges Bedran, Chan Cao, Mauro Chinappi, Etienne Coyaud, Cees Dekker, Gunnar Dittmar, Nicholas Drachman, Rienk Eelkema, David Goodlett, Sébastien Hentz, Umesh Kalathiya, Neil L. Kelleher, Ryan T. Kelly, Zvi Kelma
Published in: Nature Methods, 2021, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-021-01143-1

Full‐Length Single Protein Molecules Tracking and Counting in Thin Silicon Channels

Author(s): Shilo Ohayon, Liran Taib, Navneet Chandra Verma, Marzia Iarossi, Ivy Bhattacharya, Barak Marom, Diana Huttner, Amit Meller
Published in: Advanced Materials, Issue 36, 2024, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202314319

Microfluidic device for coupling isotachophoretic sample focusing with nanopore single-molecule sensing

Author(s): Joshua D Spitzberg; Xander F. van Kooten; Moran Bercovici; Amit Meller; Amit Meller
Published in: Nanoscale, Issue 12, 2020, Page(s) 17805 - 17811, ISSN 2040-3364
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0nr05000h

Fast and Deterministic Fabrication of Sub‑5 Nanometer Solid-State Pores by Feedback-Controlled Laser Processing

Author(s): Eran Zvuloni, Adam Zrehen, Tal Gilboa, Amit Meller
Published in: ACS Nano, 2021, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.1c03773

Quantification of mRNA Expression Using Single-Molecule Nanopore Sensing

Author(s): Yana Rozevsky, Tal Gilboa, Xander F. van Kooten, Dennis Kobelt, Diana Huttner, Ulrike Stein, Amit Meller
Published in: ACS Nano, Issue 14/10, 2020, Page(s) 13964-13974, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.0c06375

Nanopore-based technologies beyond DNA sequencing

Author(s): Yi-Lun Ying; Zheng-Li Hu; Shengli Zhang; Yujia Qing; Alessio Fragasso; Giovanni Maglia; Amit Meller; Hagan Bayley; Cees Dekker; Yi-Tao Long
Published in: Nature Nanotechnology, Issue 17, 2022, Page(s) 1136-1146, ISSN 1748-3387
Publisher: Nature Publishing Group
DOI: 10.1038/s41565-022-01193-2

On-chip protein separation with single-molecule resolution

Author(s): Adam Zrehen, Shilo Ohayon, Diana Huttner, Amit Meller
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-72463-z

Purely electrical SARS-CoV-2 sensing based on single-molecule counting

Author(s): Xander F. van Kooten; Yana Rozevsky; Yulia Marom; Efrat Ben Sadeh; Amit Meller
Published in: Nanoscale, Issue 14, 2022, Page(s) 4977-4986, ISSN 2040-3364
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1nr07787b

Nanopore Identification of Single Nucleotide Mutations in Circulating Tumor DNA by Multiplexed Ligation

Author(s): Nitza Burck, Tal Gilboa, Abhilash Gadi, Michelle Patkin Nehrer, Robert J Schneider, Amit Meller
Published in: Clinical Chemistry, 2021, ISSN 0009-9147
Publisher: American Association for Clinical Chemistry, Inc.
DOI: 10.1093/clinchem/hvaa328

Simulation of single-protein nanopore sensing shows feasibility for whole-proteome identification.

Author(s): Shilo Ohayon; Arik Girsault; Maisa Nasser; Shai S. Shen-Orr; Amit Meller; Amit Meller
Published in: PLoS Computational Biology, Vol 15, Iss 5, p e1007067 (2019), Issue 15, 2019, Page(s) e1007067, ISSN 1553-734X
Publisher: Public Library of Science
DOI: 10.1371/journal.pcbi.1007067

Single-File Translocation Dynamics of SDS-Denatured, Whole Proteins through Sub-5 nm Solid-State Nanopores

Author(s): Soni, Neeraj; Freundlich, Noam; Ohayon, Shilo; Huttner, Diana; Meller, Amit
Published in: ACS Nano, Issue 5, 2022, Page(s) 11405-11414, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.2c05391

On-Chip Stretching, Sorting, and Electro-Optical Nanopore Sensing of Ultralong Human Genomic DNA

Author(s): Adam Zrehen, Diana Huttner, Amit Meller
Published in: ACS Nano, Issue 13/12, 2019, Page(s) 14388-14398, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.9b07873

Lifetime-based analysis of binary fluorophores mixtures in the low photon count limit

Author(s): Maisa Nasser, Amit Meller
Published in: iScience, 2021, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2021.103554

Non-peer reviewed articles (1)

Are nanopore technologies ready for the proteomic challenge primetime?

Author(s): Amit Meller
Published in: Molecular Cell, Issue 82, 2022, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2021.12.018