Drosophila sechellia: a novel model to investigate nervous system and behavioral evolution

Información del proyecto

NEUROFLIES

Identificador del acuerdo de subvención: 833548

DOI

10.3030/833548

Proyecto cerrado

Fecha de la firma de la CE 8 Abril 2019

Fecha de inicio 1 Octubre 2019

Fecha de finalización 31 Marzo 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 2 327 547,00

Aportación de la UE

€ 2 327 547,00

Coordinado por

UNIVERSITE DE LAUSANNE
Switzerland

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Open Research Data Pilot (1)

Data Management Plan

Publicaciones

Peer reviewed articles (24)

Copy number changes in co-expressed odorant receptor genes enable selection for sensory differences in drosophilid species

Autores: Thomas O. Auer, Raquel Álvarez-Ocaña, Steeve Cruchet, Richard Benton, J. Roman Arguello
Publicado en: Nature Ecology & Evolution, Edición 6, 2022, Página(s) 1343-1353, ISSN 2397-334X
Editor: Springer Science and Business Media LLC
DOI: 10.1038/s41559-022-01830-y

Odor-regulated oviposition behavior in an ecological specialist

Autores: Raquel Álvarez-Ocaña, Michael P. Shahandeh, Vijayaditya Ray, Thomas O. Auer, Nicolas Gompel, Richard Benton
Publicado en: Nature Communications, Edición 14, 2023, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-023-38722-z

Olfactory receptor–dependent receptor repression in Drosophila

Autores: Kaan Mika, Steeve Cruchet, Phing Chian Chai, Lucia L. Prieto-Godino, Thomas O. Auer, Sylvain Pradervand, Richard Benton
Publicado en: Science Advances, 2021, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abe3745

Functional integration of “undead” neurons in the olfactory system

Autores: Lucia L. Prieto-Godino, Ana F. Silbering, Mohammed A. Khallaf, Steeve Cruchet, Karolina Bojkowska, Sylvain Pradervand, Bill S. Hansson, Markus Knaden, Richard Benton
Publicado en: Science Advances, Edición 6/11, 2020, Página(s) eaaz7238, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.aaz7238

Olfactory receptor and circuit evolution promote host specialization

Autores: Thomas O. Auer, Mohammed A. Khallaf, Ana F. Silbering, Giovanna Zappia, Kaitlyn Ellis, Raquel Álvarez-Ocaña, J. Roman Arguello, Bill S. Hansson, Gregory S. X. E. Jefferis, Sophie J. C. Caron, Markus Knaden, Richard Benton
Publicado en: Nature, Edición 579/7799, 2020, Página(s) 402-408, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-020-2073-7

Molecular mechanisms of olfactory detection in insects: beyond receptors

Autores: Hayden R. Schmidt, Richard Benton
Publicado en: Open Biology, Edición 10/10, 2020, Página(s) 200252, ISSN 2046-2441
Editor: Royal Society Publishing
DOI: 10.1098/rsob.200252

Olfactory receptor gene regulation in insects: multiple mechanisms for singular expression

Autores: Kaan Mika, Richard Benton
Publicado en: Frontiers in Neuroscience, 2021, ISSN 1662-453X
Editor: Frontiers Media S.A.
DOI: 10.3389/fnins.2021.738088

Remote homolog detection places insect chemoreceptors in a cryptic protein superfamily spanning the tree of life

Autores: Nathaniel J. Himmel, David Moi, Richard Benton
Publicado en: Current Biology, Edición 33, 2024, Página(s) 5023-5033.e4, ISSN 0960-9822
Editor: Cell Press
DOI: 10.1016/j.cub.2023.10.008

A putative origin of the insect chemosensory receptor superfamily in the last common eukaryotic ancestor

Autores: Richard Benton, Christophe Dessimoz, David Moi
Publicado en: eLife, Edición 9, 2020, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.62507

Drosophila sechellia: A Genetic Model for Behavioral Evolution and Neuroecology

Autores: Thomas O. Auer, Michael P. Shahandeh, RIchard Benton
Publicado en: Annual Review of Genetics, 2021, ISSN 1545-2948
Editor: Annual Reviews
DOI: 10.1146/annurev-genet-071719-020719

Structural screens identify candidate human homologs of insect chemoreceptors and cryptic Drosophila gustatory receptor-like proteins

Autores: Richard Benton, Nathaniel J Himmel
Publicado en: eLife, Edición 12, 2023, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.85537

<i>Drosophila</i> olfaction: past, present and future

Autores: Richard Benton
Publicado en: Proceedings of the Royal Society B: Biological Sciences, Edición 289, 2023, ISSN 0962-8452
Editor: Royal Society of London
DOI: 10.1098/rspb.2022.2054

Targeted molecular profiling of rare olfactory sensory neurons identifies fate, wiring, and functional determinants

Autores: J Roman Arguello, Liliane Abuin, Jan Armida, Kaan Mika, Phing Chian Chai, Richard Benton
Publicado en: eLife, Edición 10, 2021, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.63036

Chemogenetic activation of mammalian brain neurons expressing insect Ionotropic Receptors by systemic ligand precursor administration

Autores: Yoshio Iguchi, Ryoji Fukabori, Shigeki Kato, Kazumi Takahashi, Satoshi Eifuku, Yuko Maejima, Kenju Shimomura, Hiroshi Mizuma, Aya Mawatari, Hisashi Doi, Yilong Cui, Hirotaka Onoe, Keigo Hikishima, Makoto Osanai, Takuma Nishijo, Toshihiko Momiyama, Richard Benton, Kazuto Kobayashi
Publicado en: Communications Biology, Edición 7, 2024, ISSN 2399-3642
Editor: Springer Science and Business Media LLC
DOI: 10.1038/s42003-024-06223-4

Olfactory sensory neuron population expansions influence projection neuron adaptation and enhance odour tracking

Autores: Suguru Takagi, Gizem Sancer, Liliane Abuin, S. David Stupski, J. Roman Arguello, Lucia L. Prieto-Godino, David L. Stern, Steeve Cruchet, Raquel Álvarez-Ocaña, Carl F. R. Wienecke, Floris van Breugel, James M. Jeanne, Thomas O. Auer, Richard Benton
Publicado en: Nature Communications, Edición 15, 2024, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-024-50808-w

Pheromone sensing in Drosophila requires support cell-expressed Osiris 8

Autores: Marta Scalzotto, Renny Ng, Steeve Cruchet, Michael Saina, Jan Armida, Chih-Ying Su, Richard Benton
Publicado en: BMC Biology, Edición 20, 2022, ISSN 1741-7007
Editor: BioMed Central
DOI: 10.1186/s12915-022-01425-w

Enhanced Retrieval of Taste Associative Memory by Chemogenetic Activation of Locus Coeruleus Norepinephrine Neurons

Autores: Ryoji Fukabori, Yoshio Iguchi, Shigeki Kato, Kazumi Takahashi, Satoshi Eifuku, Shingo Tsuji, Akihiro Hazama, Motokazu Uchigashima, Masahiko Watanabe, Hiroshi Mizuma, Yilong Cui, Hirotaka Onoe, Keigo Hikishima, Yasunobu Yasoshima, Makoto Osanai, Ryo Inagaki, Kohji Fukunaga, Takuma Nishijo, Toshihiko Momiyama, Richard Benton, Kazuto Kobayashi
Publicado en: The Journal of Neuroscience, Edición 40/43, 2020, Página(s) 8367-8385, ISSN 0270-6474
Editor: Society for Neuroscience
DOI: 10.1523/jneurosci.1720-20.2020

Molecular reconstruction of recurrent evolutionary switching in olfactory receptor specificity

Autores: Lucia L. Prieto-Godino, Hayden R. Schmidt, Richard Benton
Publicado en: eLife, 2021, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.69732

Comparative single-cell transcriptomic atlases of drosophilid brains suggest glial evolution during ecological adaptation

Autores: Daehan Lee, Michael P. Shahandeh, Liliane Abuin, Richard Benton
Publicado en: PLOS Biology, Edición 23, 2025, Página(s) e3003120, ISSN 1545-7885
Editor: Public Library of Science (PLoS)
DOI: 10.1371/journal.pbio.3003120

Mate discrimination among subspecies through a conserved olfactory pathway

Autores: Mohammed A. Khallaf, Thomas O. Auer, Veit Grabe, Ana Depetris-Chauvin, Byrappa Ammagarahalli, Dan-Dan Zhang, Sofía Lavista-Llanos, Filip Kaftan, Jerrit Weißflog, Luciano M. Matzkin, Stephanie M. Rollmann, Christer Löfstedt, Aleš Svatoš, Hany K. M. Dweck, Silke Sachse, Richard Benton, Bill S. Hansson, Markus Knaden
Publicado en: Science Advances, Edición 6/25, 2020, Página(s) eaba5279, ISSN 2375-2548
Editor: AAAS
DOI: 10.1126/sciadv.aba5279

A chemogenetic technology using insect Ionotropic Receptors to stimulate target cell populations in the mammalian brain

Autores: Yoshio Iguchi, Richard Benton, Kazuto Kobayashi
Publicado en: Neuroscience Research, 2024, ISSN 0168-0102
Editor: Elsevier BV
DOI: 10.1016/j.neures.2024.11.003

Olfactory projection neuron rewiring in the brain of an ecological specialist

Autores: Benedikt R. Dürr, Enrico Bertolini, Suguru Takagi, Justine Pascual, Liliane Abuin, Giovanna Lucarelli, Richard Benton, Thomas O. Auer
Publicado en: Cell Reports, Edición 44, 2025, Página(s) 115615, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2025.115615

Circadian plasticity evolves through regulatory changes in a neuropeptide gene

Autores: Michael P. Shahandeh, Liliane Abuin, Lou Lescuyer De Decker, Julien Cergneux, Rafael Koch, Emi Nagoshi, Richard Benton
Publicado en: Nature, Edición 635, 2024, Página(s) 951-959, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-024-08056-x

Evolution of connectivity architecture in the Drosophila mushroom body

Autores: Kaitlyn Elizabeth Ellis, Sven Bervoets, Hayley Smihula, Ishani Ganguly, Eva Vigato, Thomas O. Auer, Richard Benton, Ashok Litwin-Kumar, Sophie Jeanne Cécile Caron
Publicado en: Nature Communications, Edición 15, 2024, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-024-48839-4

Non-peer reviewed articles (1)

Sweet sensors support stressed cell survival

Autores: Nathaniel J. Himmel, Richard Benton
Publicado en: PLOS Biology, Edición 20, 2022, Página(s) e3001705, ISSN 1545-7885
Editor: Public Library of Science (PLoS)
DOI: 10.1371/journal.pbio.3001705

Other (2)

An integrated anatomical, functional and evolutionary view of the Drosophila olfactory system

Autores: Richard Benton, Jérôme Mermet, Andre Jang, Keita Endo, Steeve Cruchet, Karen Menuz
Publicado en: bioRxiv, 2025
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.01.16.632927

Multilayer regulation underlies the functional precision and evolvability of the olfactory system

Autores: Jérôme Mermet, Steeve Cruchet, Asfa Sabrin Borbora, Daehan Lee, Phing Chian Chai, Andre Jang, Karen Menuz, Richard Benton
Publicado en: bioRxiv, 2025
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.01.16.632932