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Programmable ARTificial immune systems to fight cancer

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Dictating Phenotype, Function, and Fate of Human T Cells with Co-Stimulatory Antibodies Presented by Filamentous Immune Cell Mimics

Author(s): Schluck, M, Eggermont, LJ, Weiden, J, Popelier, C, Weiss, L, Pilzecker, B, Kolder, S, Heinemans, A, Mogeda, CR, Verdoes, M, Figdor, CG, Hammink, R.
Published in: Advanced Therapeutics, 2022, ISSN 2366-3987
Publisher: Wiley-Blackwell Publishing Ltd
DOI: 10.1002/adtp.202200019

Semiflexible Immunobrushes Induce Enhanced T Cell Activation and Expansion

Author(s): Roel Hammink, Jorieke Weiden, Dion Voerman, Carlijn Popelier, Loek J. Eggermont, Marjolein Schluck, Carl G. Figdor, Martijn Verdoes
Published in: ACS Applied Materials & Interfaces, 13/14, 2021, Page(s) 16007-16018, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.0c21994

The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture

Author(s): Di Blasio, S, van Wigcheren, GF, Becker, A, van Duffelen, A, Gorris, M, Verrijp, K, Stefanini, I, Bakker, GJ, Bloemendal, M, Halilovic, A, Vasaturo, A, Bakdash, G, Hato, SV, de Wilt, JHW, Schalkwijk, J, de Vries, IJM, Textor, JC, van den Bogaard, EH, Tazzari, M, Figdor, CG.
Published in: Nature Communications, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-16583-0

Robust Antigen-Specific T Cell Activation within Injectable 3D Synthetic Nanovaccine Depots.

Author(s): Jorieke Weiden; Marjolein Schluck; Melina Ioannidis; Eric A. W. van Dinther; Mahboobeh Rezaeeyazdi; Fawad Omar; Juulke Steuten; Dion Voerman; Jurjen Tel; Mustafa Diken; Sidi A. Bencherif; Carl G. Figdor; Martijn Verdoes
Published in: ACS Biomaterials Science & Engineering, 2, 2021, ISSN 2373-9878
Publisher: ACS Publications
DOI: 10.1021/acsbiomaterials.0c01648