Skip to main content

Precision Docking of Very Large DNA Cargos in Mammalian Genomes

Project description

Innovative technology to deliver large functional DNA circuitry into mammalian genomes

Gene editing is developing at breathtaking speed and is currently highly effective for local, small genomic DNA edits and insertions. Gene synthesis is now capable of producing thousands of DNA base pairs. The next challenge is genome engineering with the delivery of large multi-component DNA circuitry, including programmable functionalities. The EU-funded DNA-DOCK project aspires to create ground-breaking, easy-to-use technology to enable docking of large DNA cargos with base-pair precision into mammalian genomes, generating multifunctional circuits. Researchers will employ multiple sophisticated technologies to achieve these ambitious goals and accomplish precise DNA integration into specific genomic sites.

Host institution

UNIVERSITY OF BRISTOL
Net EU contribution
€ 2 498 578,00
Address
Beacon House Queens Road
BS8 1QU Bristol
United Kingdom

See on map

Region
South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Bristol, City of
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Beneficiaries (1)

UNIVERSITY OF BRISTOL
United Kingdom
Net EU contribution
€ 2 498 578,00
Address
Beacon House Queens Road
BS8 1QU Bristol

See on map

Region
South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Bristol, City of
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00