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Mitochondrial Cristae Biogenesis

Project description

Watching mitochondrial membrane formation in action for the first time

All the cells of the body require energy to do their jobs. Mitochondria, organelles found abundantly in every cell, are the so-called powerhouses. They produce a molecule that releases the energy required to support cellular functions. Mitochondrial dysfunction is associated with many varied diseases and conditions. MitoCRISTAE is applying new high-tech methods to study the development of convoluted membranes in mitochondria, whose dynamically changing structure has recently been linked to the functioning of the energy production pathway. In studies only recently possible, the team plans the pioneering investigation of membrane development over time to understand mitochondrial structure and function in health and disease.

Field of science

  • /natural sciences/chemical sciences/analytical chemistry/mass spectrometry
  • /natural sciences/physical sciences/optics/microscopy/electron microscopy
  • /natural sciences/physical sciences/optics/microscopy/super resolution microscopy

Call for proposal

ERC-2018-ADG
See other projects for this call

Funding Scheme

ERC-ADG - Advanced Grant

Host institution

UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS
Address
Robert-koch-strasse 40
37075 Goettingen
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 170 655,16

Beneficiaries (2)

UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS
Germany
EU contribution
€ 1 170 655,16
Address
Robert-koch-strasse 40
37075 Goettingen
Activity type
Higher or Secondary Education Establishments
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany
EU contribution
€ 1 115 592,84
Address
Hofgartenstrasse 8
80539 Muenchen
Activity type
Research Organisations