Description du projet
Un nouvel implant améliore les perspectives des patients souffrant d’insuffisance cardiaque
L’insuffisance cardiaque systolique survient lorsque le ventricule gauche perd sa capacité à se contracter normalement et que le cœur ne peut plus pomper efficacement le sang pour répondre aux besoins de l’organisme. Les médicaments classiques aident à gérer cette affection et peuvent améliorer la fonction cardiaque. Néanmoins, le seul remède reste la transplantation cardiaque, qui reste toutefois limitée par la disponibilité des donneurs et l’âge du patient. Pour résoudre ce problème, le projet HD4HF, financé par l’UE, a conçu un dispositif cardiaque implantable, le Heart Damper (HD), qui peut être incorporé dans le ventricule gauche. L’innovation du dispositif HD est qu’il exploite la capacité contractile résiduelle du cœur pour restaurer la fonction cardiaque et améliorer la qualité de vie des patients.
Objectif
This project supports the market introduction of the Heart Damper (HD), a very innovative implantable cardiac device, intended to provide a simple, quick and cost-effective solution to treat patients affected by systolic heart failure.
Heart Failure (HF) is a growing epidemic and a major public health issue: only in EU and US it affects today about 15 million people, with an expected growth of about 38% by 2030. 2 million of these patients are affected by advanced heart failure: a phase in which the pharmacological therapies alone are no longer sufficient to manage the symptoms. Late stage treatments, such as Ventricular Assist Device (VAD) or Total Artificial Heart (TAH) are indeed inevitably associated with high risk of rejection and low quality of life. HF has no actual cure apart from heart transplantation, which is very rare and impossible for people over 65 (80% of HF patients). In addition, HF has a significant social cost, as it doesn’t affect only the individual patient, but also his family and his community. In the US, for example, the costs related to the loss of work and household productivity are estimated at $ 8.2 billion/year (by 2030, $12.3 billion/year).
The Heart Damper, a minimally invasive cardiac device, will make it possible to give patients a longer and better life expectancy, independently from their age, at the same time reducing the staggering associated healthcare costs. Designed to be stably fitted into the left ventricle by a simple transapical surgical procedure, once implanted it moves upwards exploiting the residual contractile cacapacity of the heart, without any need of external energy sources. The device is protected by a patent fully owned by Eucardia, which has been granted in Europe, US and other major countries worldwide.
The SME 1 Instrument will enable Eucardia to assess in detail the technical feasibility and economic viability of its innovation, in order to ease HD market penetration, in respect of HF market segment.
Champ scientifique
Programme(s)
Régime de financement
SME-1 - SME instrument phase 1Coordinateur
20123 MILANO
Italie
L’entreprise s’est définie comme une PME (petite et moyenne entreprise) au moment de la signature de la convention de subvention.