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Transcriptional characterization of human postnatal and adult neural progenitors and of the stem cell niches.

Project description

Characterisation of neural progenitors in the human brain

Although neurogenesis in the adult brain has been unequivocally demonstrated in mammals, data in humans are controversial. The key objective of the EU-funded HUMANE project is to determine the existence of neural progenitors and stem cell niches in the adult human brain. For this purpose, scientists will use state-of-the-art sequencing and transcriptome methods to perform single-cell characterisation. Since neurogenesis contributes to brain plasticity in various mammals, the results of the HUMANE study could pave the way for novel strategies that tackle neurological disorders such as age-related cognitive decline or depression.

Coordinator

KAROLINSKA INSTITUTET
Net EU contribution
€ 203 852,16
Address
Nobels Vag 5
17177 Stockholm
Sweden

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Higher or Secondary Education Establishments
Other funding
€ 203 852,16