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A CutFEM Paradigm for Surgical Guided Growth of Bone Joints

Project description

Platform for the virtual prediction of the optimal paediatric orthopaedic surgery

Paediatric orthopaedic surgery may require invasive methods involving bone cutting, while other cases may recover through less invasive treatments such as guided growth surgery. Surgeons are currently lacking reliable tools to predict the postoperative evolution of bone joints, complicating the choice of the best treatment strategy. The EU-funded CutGrow project aims to develop a numerical platform for the virtual prediction of bone growth. The platform will be based on a novel finite element technology previously developed by the applicant. The CutGrow simulation approach has the potential to transform paediatric orthopaedic surgery by arming researchers with an innovative tool to probe new treatment options virtually and to plan operation procedures based on reliable simulation technologies.

Objective

Many children suffer from bone deformities, which severely hinders their ability to walk. Some children may require invasive surgical treatment, such as cutting their bones, whilst others may recover their mobility through less invasive treatments such as guided growth surgery. However, surgeons have difficulties choosing the best treatment options because there is no reliable tool to help them predict the post-operative evolution of bone joints. CutGrow aims to provide a numerical platform whereby bone growth will be predicted virtually. The platform will rely on a novel finite element technology, CutFEM, developed by the applicant, Dr. Claus, which circumvents the need for meshing complex geometries. This algorithmic concept will bestow numerical agility upon all steps of the simulation process, from acquiring patient-specific data to handling complex contact conditions between interacting bones, the latter being the domain of excellence of the host supervisor Prof. Erleben. In the first stage of CutGrow, a seamless and robust simulation pipeline in the specific context of bone joint mechanics and growth will be created. In a second stage, the simulation will be used as a basis to develop a unifying and highly versatile model for children’s bone growth, capable of easily handling a range of mathematical growth stimulus theories. Finally, we will specialize the developments to the context of guided bone growth and prove that the proposed modelling framework can reproduce clinical data gathered by MD Wong at Hvidovre Hospital. The CutGrow simulation environment has the potential to transform paediatric orthopaedic surgery, by providing researchers with an agile tool to investigate new treatment options virtually and to design new operation planning procedures based on reliable, physics based simulation technologies.

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Topic(s)

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MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

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(opens in new window) H2020-MSCA-IF-2018

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Coordinator

KOBENHAVNS UNIVERSITET
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 207 312,00
Address
NORREGADE 10
1165 KOBENHAVN
Denmark

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Region
Danmark Hovedstaden Byen København
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 207 312,00
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