4F-induced rejuvenation of glia into neural stem cells for brain repair

Project description

Reprogramming neuronal cells for brain regeneration

Neurogenesis in the adult brain is a very rare phenomenon, indicating that the regenerative capacity of the brain is limited. This has important consequences for the millions of individuals who suffer from neurological disorders. The EU-funded 4F4REJUVENGLIA project proposes an innovative rejuvenating approach to stimulate the regeneration of damaged areas of the brain. Using nuclear cell reprogramming technology, researchers will deliver four protein factors to parenchymal glia to revert cells back to neural progenitors that can give rise to new neurons. The aim is to increase the possibilities of recovering lost or damaged neurons and integrate them into the brain circuits.

Fields of science

• medical and health sciences › medical biotechnology › cells technologies › stem cells
• medical and health sciences › basic medicine › neurology

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2018 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2018

See other projects for this call

Funding Scheme

MSCA-IF-EF-ST - Standard EF

Coordinator

KING'S COLLEGE LONDON

Net EU contribution

€ 212 933,76

Address

Strand
WC2R 2LS London
United Kingdom

Region

London › Inner London — West › Westminster

Activity type

Higher or Secondary Education Establishments

Links

Non-EU contribution

€ 0,00