The research was divided into one preparation phase and three main work packages.
Preparation: This part included submitting my study protocol to the Independent Scientific Advisory Committee (see §6 Ethics), addressing any modification requests, and ensuring the data is transferred to KU Leuven. Status: Completed.
WP1 Disease phenotyping: For each cardiovascular and inflammatory condition investigated, I compiled a comprehensive list of diagnostic codes (so-called ‘phenotype’), which were needed to extract diagnoses from electronic health records. I did so following methods I have previously used and in close collaboration with my supervisor Prof. Verbakel, who is a clinician. Status: Completed.
WP2 Objective 1 and WP3 Objective 2: Each objective follows a similar research process. I have started with an in-depth literature review to identify relevant studies and synthesise a recent and comprehensive knowledge of the subject area. Then, I extracted and processed the data needed for my analysis - that is identifying the study population as defined, and extracting all exposure, covariate and outcome variables. Thereafter, I performed the statistical analysis of the data as defined in the scientific research proposal, and presented findings graphically. Status: Completed
After reviewing and synthesizing the results, I will combine these with the results of my literature review to prepare a manuscript, invite and incorporate co-authors' reviews, and submit it for publication. Further work packages ensure an optimal execution of the personal development, impact and management aspects of the fellowship. Status: Ongoing (delayed due to the covid-19 pandemic)
WP4 Training and career development refers to activities presented in section 1.2 WP5 Outreach activities to activities described in sections 2.2/2.3. Status : cancelled due to the covid-19 pandemic.
WP6 Project management to activities outlined in section 3.2. Status: Completed