Monitoring cancer heterogeneity based on the dynamic assessment of the Warburg effect under metabolic perturbation

Project description

Metabolic imaging in cancer diagnostics

Cancer diagnosis and treatment monitoring rely on molecular imaging methods which, however, cannot fully portray disease heterogeneity. To address this problem, the EU-funded CHyMERA project proposes to develop a novel technology that can image cancer phenotypes. The approach measures the kinetics of glucose flux through different metabolic pathways under different tumour microenvironment conditions and their association with cell proliferation. The CHyMERA methodology has a strong potential for clinical translation and is expected to improve specificity to cancer diagnosis and monitoring of treatment response.

Fields of science

• medical and health sciences › clinical medicine › oncology

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2018 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2018

See other projects for this call

Funding Scheme

MSCA-IF-EF-ST - Standard EF

Coordinator

FUNDACAO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD

Net EU contribution

€ 159 815,04

Address

Avenida Brasilia, Centro De Investigacao Da Fundacao Champalimaud
1400-038 Lisboa
Portugal

Region

Continente › Área Metropolitana de Lisboa › Área Metropolitana de Lisboa

Activity type

Research Organisations

Links

Non-EU contribution

€ 0,00