Deliverables
Motor emotional and learning deficits shared or unique to the different mouse models
First study approvals packageFirst study subject approvals package (prior to enrolment of first study subject). (i) Final version of study protocol as submitted to regulators/ethics committee(s), (ii) Registration number of clinical study in a WHO-or ICMJE- approved registry (with the possibility to post results), (iii) Approvals (ethics committees and national competent authority if applicable) required for invitation/enrolment of first subject in at least one clinical centre.
Communication, Dissemination and Exploitation plan (first release)First release of the Communication, Dissemination and Exploitation Plan.
First study subject approvals packageFirst study subject approvals package' (prior to enrolment of first study subject). (i) Final version of study protocol as submitted to regulators/ethics committee(s), (ii) Registration number of clinical study in a WHO-or ICMJE- approved registry (with the possibility to post results), (iii) Approvals (ethics committees and national competent authority if applicable) required for invitation/enrolment of first subject in at least one clinical centre.
Questionnaire definitionDefinition of a questionnaire that will be distributed via UPPMD to national advocacy groups and registries
Mdx5cv validationValidation of the mdx5cv mouse model
Gene and proteomic knowledge mapKnowledge map of gene and proteomic changes associated with comorbidities in other than DMDBMD
Comorbidity ‘supercluster' formationFormation of brain comorbidity supercluster and clinical trial advisory group on brain comorbidities
Brain transcriptional changesCharacterization of transcriptional changes in different brain regions of mouse models lacking different dystrophin isoforms
WP5 - Midterm recruitment reportMidterm recruitment report Report for each clinical study to be scheduled for the point when 50 of the study population is expected to have been recruited
Dystrophin isoform localisation:humansCharacterisation of dystrophin isoform localisation in different brain regions from normal human brains
Protocol optimisationOptimization of the neurocognitive and neurobehavioural protocols to be used in the study
Communication, Dissemination and Exploitation plan (second release)Second release of the Communication, Dissemination and Exploitation Plan.
WP6 - Midterm recruitment reportMidterm recruitment report Report for each clinical study to be scheduled for the point when 50 of the study population is expected to have been recruited
The project website will be formally delivered in month 4, carrying general information about BIND and the planned public deliverables; it will then be updated at regular intervals, to report on activities, events, major achievements and to provide access to public deliverables.
Publications
Author(s):
Mary Chesshyre, Deborah Ridout, Yasumasa Hashimoto, Yoko Ookubo, Silvia Torelli, Kate Maresh, Valeria Ricotti, Lianne Abbott, Vandana Ayyar Gupta, Marion Main, Giulia Ferrari, Anna Kowala, Yung-Yao Lin, Francesco Saverio Tedesco, Mariacristina Scoto, Giovanni Baranello, Adnan Manzur, Yoshitsugu Aoki, Francesco Muntoni
Published in:
Journal of Cachexia, Sarcopenia and Muscle, 2022, ISSN 2190-5991
Publisher:
Springer Verlag
DOI:
10.1002/jcsm.12914
Author(s):
A. Saoudi, S. Barberat, O. Le Coz, O. Vacca, M. Doisy Caquant, Tensorer, E. Sliwinski, L. Garcia, F. Muntoni, C. Vaillend and A. Goyenvalle
Published in:
Molecular Therapy Nucelic Acids, 2023, ISSN 2162-2531
Publisher:
Nature Publishing Group
DOI:
10.1016/j.omtn.2023.03.009
Author(s):
Rachel E. Trimmer, William P.L. Mandy, Francesco Muntoni, Kate E. Maresh
Published in:
Neuromuscular Disorders, 2024, ISSN 0960-8966
Publisher:
Elsevier BV
DOI:
10.1016/j.nmd.2023.12.002
Author(s):
F. Zarrouki, S. Goutal, O. Vacca, L. Garcia, N. Tournier, A. Goyenvalle, and C. Vaillend
Published in:
International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ijms232012617
Author(s):
Saba Gharibi, Cyrille Vaillend, Angus Lindsay
Published in:
Progress in Neurobiology, 2024, ISSN 0301-0082
Publisher:
Pergamon Press Ltd.
DOI:
10.1016/j.pneurobio.2024.102590
Author(s):
Francesco Muntoni and Mary Chessyre (UCL)
Published in:
Journal of Cachexia, Sarcopenia and Muscle, 2022, ISSN 2190-6009
Publisher:
Wiley
DOI:
10.1002/jcsm.12914
Author(s):
Cyrille Vaillend, A. Saoudi, F. Zarrouki, C. Sebrié, C. Izabelle, A. Goyenvalle, C. Vaillend
Published in:
Disease Models and Mechanisms, 2021, ISSN 1754-8411
Publisher:
The company of Biologists
DOI:
10.1242/dmm.049028
Author(s):
Ophélie Vacca, Faouzi Zarrouki, Charlotte Izabelle, Mehdi Belmaati Cherkaoui, Alvaro Rendon, Deniz Dalkara, Cyrille Vaillend
Published in:
Cells, 2024, ISSN 2073-4409
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/cells13080718
Author(s):
P. Weerkamp, E. Mol, D. Sweere, D. Schrans, R. J. Vermeulen, S. Klinkenberg, P. Hurks and J. Hendriksen
Published in:
Brain Sciences, 2022, ISSN 2076-3425
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/brainsci12111544
Author(s):
Kate Maresh,Andriani Papageorgiou,
Deborah Ridout,
Neil Harrison,
William Mandy,
David Skuse,
Francesco Muntoni
Published in:
Plos one, 2022, ISSN 1932-6203
Publisher:
Public Library of Science
DOI:
10.1371/journal.pone.0264091
Author(s):
Mathilde Doisy, Ophélie Vacca, Claire Fergus, Talia Gileadi, Minou Verhaeg, Amel Saoudi, Thomas Tensorer, Luis Garcia, Vincent P Kelly, Federica Montanaro, Jennifer E Morgan, Maaike van Putten, Annemieke Aartsma-Rus , Cyrille Vaillend, Francesco Muntoni, Aurélie Goyenvalle
Published in:
Biomedicines, 2024, ISSN 2227-9059
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/biomedicines11123243
Author(s):
P. Weerkamp, P. Collin, R. Maas, R. J. Vermeulen, S. Klinkenberg, J. Hendriksen
Published in:
Neuromuscular Disorders, 2022, ISSN 1873-2364
Publisher:
Elsevier
DOI:
10.1016/j.nmd.2021.10.008
Author(s):
Pien Weerkamp, Daniela Chieffo, Philippe Collin, Federica Moriconi, Andriani Papageorgiou, Isabella Vainieri, Ruben Miranda, Catherine Hankinson, Asmus Vogel, Sarah Poncet, Catherine Moss, Francesco Muntoni, Eugenio Mercuri, Jos Hendriksen
Published in:
European Journal of Paediatric Neurology, 2023, ISSN 1090-3798
Publisher:
W. B. Saunders Co., Ltd.
DOI:
10.1016/j.ejpn.2023.06.007
Author(s):
Daniela P R Chieffo, Federica Moriconi, Marika Pane, Simona Lucibello, Elisabetta Ferraroli, Giulia Norcia, Martina Ricci, Anna Capasso, Gianpaolo Cicala, Bianca Buchignani , Giorgia Coratti, Costanza Cutrona, Monia Pelizzari, Claudia Brogna, Jos G M Hendriksen, Francesco Muntoni, Eugenio Mercuri
Published in:
Journal of Clinical Medicine, 2023, ISSN 2077-0383
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/jcm12020403
Author(s):
A. Saoudi, C. Fergu, T. Gileadi, F. Montanaro, JE Morgan, V. Kelly, T. Tensorer, L. Garcia, C. Vaillend, F. Muntoni and A. Goyenvalle
Published in:
Cells, 2023, ISSN 2073-4409
Publisher:
MDPI
DOI:
10.3390/cells12060908
Author(s):
Rubén Miranda, Léa Ceschi, Delphine Le Verger, Flora Nagapin, Jean-Marc Edeline, Rémi Chaussenot, Cyrille Vaillend
Published in:
Behavioral and Brain Functions, Issue 20, 2024, Page(s) https://behavioralandbrainfunctions.biomedcentral.com/articles/10.1186/s12993-024-00246-x, ISSN 1744-9081
Publisher:
BioMed Central
DOI:
10.1186/s12993-024-00246-x
Author(s):
Mathilde Doisy, Ophélie Vacca, Claire Fergus, Talia Gileadi, Minou Verhaeg, Amel Saoudi, Thomas Tensorer, Luis Garcia, Vincent P Kelly, Federica Montanaro, Jennifer E Morgan, Maaike van Putten, Annemieke Aartsma-Rus , Cyrille Vaillend, Francesco Muntoni, Aurélie Goyenvalle
Published in:
Biomedicines, 2023, ISSN 2227-9059
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/biomedicines11123243
Author(s):
Language Development in Preschool Duchenne Muscular Dystrophy Boys
Published in:
Brain Sciences, 2022, ISSN 2076-3425
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/brainsci12091252
Author(s):
Faouzi Zarrouki
Karima Relizani Flavien Bizot
Thomas Tensorer
Luis Garcia
Cyrille Vaillend
Aurélie Goyenvalle
Published in:
Ann Neurol., 2022, ISSN 0364-5134
Publisher:
John Wiley & Sons Inc.
DOI:
10.1002/ana.26409
Author(s):
Hashimoto Y, Kuniishi H, Sakai K, Fukushima Y, Du X, Yamashiro K, Hori K, Motohashi N, Imamura M, Hoshino M, Yamada M, Araki T, Sakagami H, Takeda S, Itaka K, Ichinohe N, Muntoni F, Sekiguchi M, Aoki Y.
Published in:
Prog Neurobiol., 2021, ISSN 0301-0082
Publisher:
Pergamon Press Ltd.
DOI:
10.1016/j.pneurobio.2022.102288
Author(s):
Kate Maresh, Andriani Papageorgiou, Deborah Ridout, Neil A Harrison, William Mandy, David Skuse, Francesco Muntoni
Published in:
Research Article (peer reviewed), 2022, ISSN 1460-2156
Publisher:
Oxford University Press
DOI:
10.1093/brain/awac048
Searching for OpenAIRE data...
There was an error trying to search data from OpenAIRE
No results available