Prevention and Remediation of Insulin Multimorbidity in Europe

Livrables

Report on familial co-aggregation of insulin-related morbidities and compulsivity disorders in a multi-generational nationwide cohort study

Report on familial coaggregation of insulinrelated morbidities and compulsivity disorders in a multigenerational nationwide cohort study

Report on incidence, risk, time trends and lifetime course of compulsive and (non-compulsive) brain disorders in Danish individuals with and without insulin-related morbidities

Report on incidence risk time trends and lifetime course of compulsive and noncompulsive brain disorders in Danish individuals with and without insulinrelated morbidities

Report on comorbidity of compulsivity, learning difficulties, and diabetes in TALLYHO mice

Report on comorbidity of compulsivity learning difficulties and diabetes in TALLYHO mice

Communication and outreach plan
Report on epigenetic analysis of insulinopathies
Report on the genetic overlap between somatic and neurodegenerative brain insulinopathies and related traits
Report on the effect of insulin signalling markers on cognitive impairment and AD biomarkers
Report on the association of compulsive traits and/or cognitive rigidity with insulin signalling markers and/or somatic insulin-related disorders in participants of the UK Biobank

Report on the association of compulsive traits andor cognitive rigidity with insulin signalling markers andor somatic insulinrelated disorders in participants of the UK Biobank

Campfire Session at ECNP Congress

Go-online of the public project website

Goonline of the public project website

Publications

Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis (ru.nl)

Auteurs: Jorim J.Tielbeek et al.
Publié dans: Molecular Psychiatry, 2021, ISSN 1359-4184
Éditeur: Nature Publishing Group
DOI: 10.1038/s41380-022-01793-3

The translational genetics of ADHD and related phenotypes inmodel organisms

Auteurs: Judit Cabana-Domínguez, Ester Antón-Galindo, Noèlia Fernàndez-Castillo, Euginia L Singgih, Aet O'Leary, William Hg Norton, Tatyana Strekalova, Annette Schenck , Andreas Reif, Klaus-Peter Lesch, David Slattery , Bru Cormand
Publié dans: Neuroscience and Biobehavioural Review, 2023, ISSN 0149-7634
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2022.104949

Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

Auteurs: Joanna Martin; Ekaterina A. Khramtsova; Slavina B. Goleva; Gabriëlla A.M. Blokland; Michela Traglia; Raymond K. Walters; Christopher Hübel; Jonathan R.I. Coleman; Gerome Breen; Anders D. Børglum; Ditte Demontis; Jakob Grove; Thomas Werge; Janita Bralten; Cynthia M. Bulik; Phil H. Lee; Carol A. Mathews; Roseann E. Peterson; Stacey J. Winham; Naomi Wray; Howard J. Edenberg; Wei Guo; Yin Yao; Benj
Publié dans: Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium 2021 , ' Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral Traits ' , Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2020.12.024, Numéro 1, 2021, Page(s) 1127-1137, ISSN 0006-3223
Éditeur: Elsevier BV
DOI: 10.1101/2020.05.04.076042

Interplay between cognition and weight reduction in individuals following a Mediterranean Diet: Three-year follow-up of the PREDIMED-Plus trial.

Auteurs: Natalia Soldevila-Domenech; Laura Forcano; Cristina Vintró-Alcaraz; Aida Cuenca-Royo; Xavier Pintó; Susana Jiménez-Murcia; Jesús García-Gavilán; Stephanie K. Nishi; Nancy Babio; Maria Gomis-González; Dolores Corella; Dolores Corella; José V. Sorlí; José V. Sorlí; Rebeca Fernández-Carrión; Rebeca Fernández-Carrión; Miguel Ángel Martínez-González; Amelia Marti; Amelia Marti; Jordi
Publié dans: Clinical Nutritions, Numéro 10, 2021, ISSN 0261-5614
Éditeur: Churchill Livingstone
DOI: 10.1016/j.clnu.2021.07.020

Temporally ordered associations between type 2 diabetes and brain disorders - a Danish register-based cohort study

Auteurs: Theresa Wimberley; Henriette T. Horsdal; Isabell Brikell; Thomas M. Laursen; Aske Astrup; Giuseppe Fanelli; Janita Bralten; Geert Poelmans; Veerle Van Gils; Willemijn J. Jansen; Stephanie J. B. Vos; Valérie Bertaina-Anglade; Lucia Camacho-Barcia; Bernat Mora-Maltas; Fernando Fernandez-Aranda; Mònica B. Bonet; Jordi Salas-Salvadó; Barbara Franke; Søren Dalsgaard
Publié dans: VOLUME=22;ISSUE=1;ISSN=1471-244X;TITLE=BMC Psychiatry, Numéro 2, 2022, ISSN 1471-244X
Éditeur: BioMed Central
DOI: 10.1186/s12888-022-04163-z

Metformin Use and Cognitive Function in Older Adults With Type 2 Diabetes Following a Mediterranean Diet Intervention

Auteurs: Natalia Soldevila-Domenech; Natalia Soldevila-Domenech; Aida Cuenca-Royo; Nancy Babio; Nancy Babio; Laura Forcano; Laura Forcano; Stephanie Nishi; Stephanie Nishi; Cristina Vintró-Alcaraz; Cristina Vintró-Alcaraz; Cristina Vintró-Alcaraz; Carlos Gómez-Martínez; Carlos Gómez-Martínez; Susana Jiménez-Murcia; Susana Jiménez-Murcia; Susana Jiménez-Murcia; Susana Jiménez-Murcia; Rebeca Fern
Publié dans: Frontiers in nutrition, Numéro 9, 2021, ISSN 2296-861X
Éditeur: Frontiers Media S.A.
DOI: 10.3389/fnut.2021.742586

Effects of a psychosocial intervention at one-year follow-up in a PREDIMED-plus sample with obesity and metabolic syndrome

Auteurs: Núria Mallorquí-Bagué, María Lozano-Madrid, Cristina Vintró-Alcaraz, Laura Forcano, Andrés Díaz-López, Ana Galera, Rebeca Fernández-Carrión, Roser Granero, Susana Jiménez-Murcia, Dolores Corella, Xavier Pintó, Aida Cuenca-Royo, Mònica Bulló, Jordi Salas-Salvadó, Rafael de la Torre, Fernando Fernández-Aranda
Publié dans: Scientific Reports, Numéro 11/1, 2021, Page(s) Sci Rep 11, 9144, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-021-88298-1

Emotional regulation in eating disorders and gambling disorder: A transdiagnostic approach

Auteurs: Lucero Munguía, Susana Jiménez-Murcia, Roser Granero, Isabel Baenas, Zaida Agüera, Isabel Sánchez, Ester Codina, Amparo del Pino-Gutiérrez, Guilia Testa, Janet Treasure, Fernando Fernández-Aranda
Publié dans: Journal of Behavioral Addictions, Numéro 2063-5303, 2021, Page(s) 2063-5303, ISSN 2062-5871
Éditeur: Akademiai Kiado
DOI: 10.1556/2006.2021.00017

Transdiagnostic Perspective of Impulsivity and Compulsivity in Obesity: From Cognitive Profile to Self-Reported Dimensions in Clinical Samples with and without Diabetes

Auteurs: Testa G. et al.
Publié dans: Nutrients, 2021, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13124426

Impulsive personality traits predicted weight loss in individuals with type 2 diabetes after 3 years of lifestyle interventions

Auteurs: Giulia Testa; Lucía Camacho-Barcia; Carlos Gómez-Martínez; Bernat Mora-Maltas; Rafael de la Torre; Xavier Pintó; Dolores Corella; Roser Granero; Aida Cuenca-Royo; Susana Jiménez-Murcia; Nancy Babio; Rebeca Fernández-Carrión; Virginia Esteve-Luque; Laura Forcano; Jiaqi Ni; Mireia Malcampo; Sara De las Heras-Delgado; Montse Fitó; Jordi Salas-Salvadó; Fernando Fernández-Aranda
Publié dans: Journal of Clinical medicine, Numéro 2, 2022, ISSN 2077-0383
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm11123476

Dairy Product Consumption and Changes in Cognitive Performance: Two-Year Analysis of the PREDIMED-Plus Cohort

Auteurs: Stephanie Nishi; Itziar Salaverría Lete; Rosa Casas; Helmut Schroder; Miguel A. Martinez-Gonzalez; Carolina Donat; Jordi Salas-Salvadó; Alice Chaplin; Carlos Gómez Martínez; Jesus Vioque; Jiaqi Ni
Publié dans: Molecular nutrition and food research, Numéro 8, 2022, ISSN 1613-4125
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/mnfr.202101058

Impulsivity is longitudinally associated with healthy and unhealthy dietary patterns in individuals with overweight or obesity and metabolic syndrome within the framework of the PREDIMED-Plus trial

Auteurs: Carlos Gómez-Martínez; Nancy Babio; Jordi Júlvez; Stephanie K. Nishi; Fernando Fernández-Aranda; Miguel Ángel Martínez-González; Aida Cuenca-Royo; Rebeca Fernández; Susana Jiménez-Murcia; Rafael de la Torre; Xavier Pintó; Mirjam Bloemendaal; Montse Fitó; Dolores Corella; Alejandro Arias; Jordi Salas-Salvadó
Publié dans: Int J Behav Nutr Phys Act., Numéro 3, 2022, Page(s) 101, ISSN 1479-5868
Éditeur: BioMed Central
DOI: 10.1186/s12966-022-01335-8

The link between cognition and somatic conditions related to insulin resistance in the UK Biobank study cohort: a systematic review

Auteurs: Giuseppe Fanelli, Nina Roth Mota, Jordi Salas-Salvadó, Mònica Bulló, Fernando Fernandez-Aranda, Lucía Camacho-Barcia, Giulia Testa, Susana Jiménez-Murcia, Valérie Bertaina-Anglade, Barbara Franke, Geert Poelmans, Veerle van Gils, Willemijn J Jansen, Stephanie J B Vos, Theresa Wimberley, Søren Dalsgaard, Csaba Barta, Alessandro Serretti, Chiara Fabbri, Janita Bralten
Publié dans: Neuroscience and Biobehavioural Review, 2022, ISSN 0149-7634
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2022.104927

Annual Research Review: Perspectives on progress in ADHD science – from characterization to cause

Auteurs: Edmund J.S. Sonuga-Barke, Stephen P. Becker, Sven Bölte, Francisco Xavier Castellanos, Barbara Franke, Jeffrey H. Newcorn, Joel T. Nigg, Luis Augusto Rohde, Emily Simonoff
Publié dans: Journal of Child Psychology and Psychiatry, Numéro n.a., 2022, Page(s) n/a - n/a, ISSN 0021-9630
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/jcpp.13696

Shared genetic etiology between obsessive-compulsive disorder, obsessive-compulsive symptoms in the population, and insulin signaling

Auteurs: Janita Bralten, Joanna Widomska, Ward De Witte, Dongmei Yu, Carol A. Mathews, Jeremiah M. Scharf, Jan Buitelaar, Jennifer Crosbie, Russell Schachar, Paul Arnold, Mathieu Lemire, Christie L. Burton, Barbara Franke, Geert Poelmans
Publié dans: Translational Psychiatry, Numéro 10/1, 2020, Page(s) 121, ISSN 2158-3188
Éditeur: Nature Publishing Group
DOI: 10.1038/s41398-020-0793-y

Mediterranean, DASH, and MIND Dietary Patterns and Cognitive Function: The 2-Year Longitudinal Changes in an Older Spanish Cohort

Auteurs: Stephanie K. Nishi; Stephanie K. Nishi; Stephanie K. Nishi; Stephanie K. Nishi; Stephanie K. Nishi; Nancy Babio; Nancy Babio; Nancy Babio; Nancy Babio; Carlos Gómez-Martínez; Carlos Gómez-Martínez; Carlos Gómez-Martínez; Miguel Ángel Martínez-González; Miguel Ángel Martínez-González; Miguel Ángel Martínez-González; Emilio Ros; Emilio Ros; Dolores Corella; Dolores Corella; Olga Casta
Publié dans: Neurocognitive Aging and Behavior, Numéro 6, 2021, ISSN 1663-4365
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fnagi.2021.782067

Metabolic, Affective and Neurocognitive Characterization of Metabolic Syndrome Patients with and without Food Addiction. Implications for Weight Progression

Auteurs: Lucía Camacho-Barcia, Lucero Munguía, Ignacio Lucas, Rafael de la Torre, Jordi Salas-Salvadó, Xavier Pintó, Dolores Corella, Roser Granero, Susana Jiménez-Murcia, Inmaculada González-Monje, Virginia Esteve-Luque, Aida Cuenca-Royo, Carlos Gómez-Martínez, Indira Paz-Graniel, Laura Forcano, Fernando Fernández-Aranda
Publié dans: Nutrients, Numéro 13/8, 2021, Page(s) 2779, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13082779

Glycemic Dysregulations Are Associated With Worsening Cognitive Function in Older Participants at High Risk of Cardiovascular Disease: Two-Year Follow-up in the PREDIMED-Plus Study.

Auteurs: Carlos Gómez-Martínez; Carlos Gómez-Martínez; Carlos Gómez-Martínez; Nancy Babio; Nancy Babio; Nancy Babio; Nancy Babio; Jordi Júlvez; Nerea Becerra-Tomás; Nerea Becerra-Tomás; Nerea Becerra-Tomás; Miguel Á. Martínez-González; Miguel Á. Martínez-González; Miguel Á. Martínez-González; Dolores Corella; Dolores Corella; Olga Castañer; Olga Castañer; Dora Romaguera; Dora Romaguera
Publié dans: instname:Universidad de Barcelona, Numéro 8, 2021, ISSN 1664-2392
Éditeur: Frontiers Media
DOI: 10.3389/fendo.2021.754347

P.169 Genetic overlap between somatic insulin-related and neuro-psychiatric disorders

Auteurs: G. Fanelli, F. Barbara, W. De Witte, N.R. Mota, G. Poelmans, J. Bralten
Publié dans: European Neuropsychopharmacology, Numéro 40, 2020, Page(s) S97-S98, ISSN 0924-977X
Éditeur: Elsevier BV
DOI: 10.1016/j.euroneuro.2020.09.130

Insulinopathies of the brain? Genetic overlap between somatic insulin-related and neuropsychiatric disorders

Auteurs: Giuseppe Fanelli, Barbara Franke, Ward De Witte, I. Hyun Ruisch, Jan Haavik, Veerle van Gils, Willemijn J. Jansen, Stephanie J. B. Vos, Lars Lind, Jan K. Buitelaar, Tobias Banaschewski, Søren Dalsgaard, Alessandro Serretti, Nina Roth Mota, Geert Poelmans, Janita Bralten
Publié dans: 2021
Éditeur: medRxiv's
DOI: 10.1101/2021.05.28.21258000

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