Cancer heterogeneity and therapy profiling using bioresponsive nanohydrogels for the delivery of multicolor logic genetic circuits.

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

The global burden of adolescent and young adult cancer in 2019: An analysis of the Global Burden of Disease Study 2019

Author(s): João Conde & GBD Consortium
Published in: The Lancet Oncology, Issue 14702045, 2022, ISSN 1470-2045
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1470-2045(21)00581-7

Why Go NANO on COVID-19 Pandemic?

Author(s): Sepehr Talebian, João Conde
Published in: Matter, Issue 3/3, 2020, Page(s) 598-601, ISSN 2590-2385
Publisher: Cell Press
DOI: 10.1016/j.matt.2020.08.005

Nanotechnology-based disinfectants and sensors for SARS-CoV-2

Author(s): Sepehr Talebian, Gordon G. Wallace, Avi Schroeder, Francesco Stellacci, João Conde
Published in: Nature Nanotechnology, Issue 15/8, 2020, Page(s) 618-621, ISSN 1748-3387
Publisher: Nature Publishing Group
DOI: 10.1038/s41565-020-0751-0

Global, regional, and national burden of colorectal cancer and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019

Author(s): João Conde & GBD Consortium
Published in: The Lancet Gastroenterology & Hepatology, Issue 24681253, 2022, ISSN 2468-1253
Publisher: The Lancet
DOI: 10.1016/s2468-1253(22)00044-9

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019

Author(s): Katherine R Paulson, Aruna M Kamath, Tahiya Alam, Kelly Bienhoff, Gdiom Gebreheat Abady, Jaffar Abbas, Mohsen Abbasi-Kangevari, Hedayat Abbastabar, Foad Abd-Allah, Sherief M Abd-Elsalam, Amir Abdoli, Aidin Abedi, Hassan Abolhassani, Lucas Guimarães Abreu, Eman Abu-Gharbieh, Niveen ME Abu-Rmeileh, Abdelrahman I Abushouk, Aishatu L Adamu, Oladimeji M Adebayo, Adeyinka Emmanuel Adegbosin, Victor Ade
Published in: The Lancet, Issue 398/10303, 2021, Page(s) 870-905, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(21)01207-1

Cancer Incidence, Mortality, Years of Life Lost, Years Lived with Disability, and Disability-Adjusted Life Years for 29 Cancer Groups from 2010 to 2019: A Systematic Analysis of Cancer Burden Globally, Nationally, and by Socio-Demographic Index for the Global Burden of Disease Study 2019

Author(s): João Conde & GBD Consortium
Published in: JAMA oncology, Issue 23742445, 2022, ISSN 2374-2445
Publisher: American Medical Association
DOI: 10.1001/jamaoncol.2021.6987

Above and Beyond Cancer Therapy: Translating Biomaterials into the Clinic

Author(s): João Conde
Published in: Trends in Cancer, Issue 6/9, 2020, Page(s) 730-732, ISSN 2405-8033
Publisher: Cell Press
DOI: 10.1016/j.trecan.2020.04.008

The global burden of cancer attributable to risk factors, 2010–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author(s): João Conde & GBD Consortium
Published in: The Lancet, Issue 01406736, 2022, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(22)01438-6

Localized nanotheranostics: recent developments in cancer nanomedicine

Author(s): R. Prasad, N.K. Jain, J. Conde, R. Srivastava
Published in: Materials Today Advances, Issue 8, 2020, Page(s) 100087, ISSN 2590-0498
Publisher: Materials Today Advances
DOI: 10.1016/j.mtadv.2020.100087

Nanodelivery of nucleic acids

Author(s): ”. Bárbara B. Mendes, João Conniot, A. Avital, D. Yao, X. Jiang, X. Zhou, O. Adir, Y. Xiao, N. Sharf-Pauker, H. Liang*, J. Shi*, A. Schroeder* and João Conde*
Published in: Nature Reviews Methods Primers, Issue 26628449, 2022, ISSN 2662-8449
Publisher: Nature
DOI: 10.1038/s43586-022-00115-9

Revisiting gene delivery to the brain: silencing and editing

Author(s): João Conniot, Sepehr Talebian, Susana Simões, Lino Ferreira, João Conde
Published in: Biomaterials Science, Issue 9/4, 2021, Page(s) 1065-1087, ISSN 2047-4830
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0bm01278e

Macrophage Cell Membrane-Cloaked Nanoplatforms for Biomedical Applications

Author(s): J. Lopes, D. Lopes, M. Pereira-Silva, D. Peixoto, F. Veiga, M.R. Hamblin, João Conde, C. Corbo, E.N. Zare, M. Ashrafizadeh, F.R. Tay, C. Chen, X. Wang, P. Makvandi and A.C. Santos
Published in: Small Methods, Issue 23669608, 2022, ISSN 2366-9608
Publisher: Wiley
DOI: 10.1002/smtd.202200289

Bioinspired soft nanovesicles for site‐selective cancer imaging and targeted therapies

Author(s): Rajendra Prasad; João Conde
Published in: Crossref, Issue 19395116, 2022, ISSN 1939-5116
Publisher: Wiley
DOI: 10.1002/wnan.1792

Nucleic acid-based therapy for brain cancer: Challenges and strategies

Author(s): Zixia Zhang 1, João Conniot 2, Joana Amorim 2, Yiliang Jin 3, Rajendra Prasad 4, Xiyun Yan 5, Kelong Fan 6, João Conde 7
Published in: J Control Release, Issue 01683659, 2022, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2022.08.014

Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

Author(s): Natalia V Bhattacharjee, Austin E Schumacher, Amirali Aali, Yohannes Habtegiorgis Abate, Rouzbeh Abbasgholizadeh, Mohammadreza Abbasian, Mohsen Abbasi-Kangevari, Hedayat Abbastabar, Samar Abd ElHafeez, Sherief Abd-Elsalam, Mohammad Abdollahi, Mohammad-Amin Abdollahifar, Meriem Abdoun, Auwal Abdullahi, Mesfin Abebe, Samrawit Shawel Abebe, Olumide Abiodun, Hassan Abolhassani, Meysam Abolmaali, Moham
Published in: The Lancet, Issue 403, 2024, Page(s) 2057-2099, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(24)00550-6

Hydrogels for RNA delivery

Author(s): Ruibo Zhong, Sepehr Talebian, Bárbara B Mendes, Gordon Wallace, Robert Langer, João Conde, Jinjun Shi
Published in: Nature Materials, 2023, ISSN 1476-1122
Publisher: Nature Publishing Group
DOI: 10.1038/s41563-023-01472-w

Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

Author(s): Rajendra Prasad, Nishant K. Jain, Amit S. Yadav, Deepak S. Chauhan, Janhavi Devrukhkar, Mukesh K. Kumawat, Shweta Shinde, Mahadeo Gorain, Avnesh S. Thakor, Gopal C. Kundu, João Conde, Rohit Srivastava
Published in: Communications Biology, Issue 3/1, 2020, ISSN 2399-3642
Publisher: Nature
DOI: 10.1038/s42003-020-1016-z

Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021

Author(s): Stein Emil Vollset, Hazim S Ababneh, Yohannes Habtegiorgis Abate, Cristiana Abbafati, Rouzbeh Abbasgholizadeh, Mohammadreza Abbasian, Hedayat Abbastabar, Abdallah H A Abd Al Magied, Samar Abd ElHafeez, Atef Abdelkader, Michael Abdelmasseh, Sherief Abd-Elsalam, Parsa Abdi, Mohammad Abdollahi, Meriem Abdoun, Auwal Abdullahi, Mesfin Abebe, Olumide Abiodun, Richard Gyan Aboagye, Hassan Abolhassani, Mo
Published in: The Lancet, Issue 403, 2024, Page(s) 2204-2256, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(24)00685-8

Magnetite and bismuth sulfide Janus heterostructures as radiosensitizers for in vivo enhanced radiotherapy in breast cancer

Author(s): H. Nosrati, M. Ghaffarlou, M. Salehiabar, N. Mousazadeh,F. Abhari, M. Barsbay, Y.N. Ertas, H. Rashidzadeh, A. Mohammadi, L. Nasehi, H. Rezaeejam, S. Davaran, A. Ramazani*, João Conde* and H. Danafar
Published in: Biomaterials Advances, Issue 27729508, 2022, ISSN 2772-9508
Publisher: Elsevier
DOI: 10.1016/j.bioadv.2022.213090

mRNA therapy at the convergence of genetics and nanomedicine

Author(s): João Conde, Robert Langer, José Rueff
Published in: Nature Nanotechnology, 2023, ISSN 1748-3395
Publisher: Nature
DOI: 10.1038/s41565-023-01347-w

Osteogenic Differentiation of Human Mesenchymal Stem Cells by the Single Action of Luminescent Polyurea Oxide Biodendrimers

Author(s): Rita F. Pires, João Conde, Vasco D. B. Bonifácio
Published in: ACS Applied Bio Materials, Issue 3/12, 2020, Page(s) 9101-9108, ISSN 2576-6422
Publisher: ACS Applied Bio Materials
DOI: 10.1021/acsabm.0c01315

Controlled delivery of gold nanoparticle-coupled miRNA therapeutics via an injectable self-healing hydrogel.

Author(s): Casper F T van der Ven; Mark W. Tibbitt; Mark W. Tibbitt; João Conde; Alain van Mil; Jesper Hjortnaes; Pieter A. Doevendans; Joost P.G. Sluijter; Elena Aikawa; Elena Aikawa; Robert Langer
Published in: Nanoscale, Issue 20403372, 2021, ISSN 2040-3372
Publisher: Royal Society of Chemistry
DOI: 10.3929/ethz-b-000518640

Nanomedicine-based strategies to target and modulate the tumor microenvironment

Author(s): Bárbara B. Mendes, Diana P. Sousa, João Conniot, João Conde
Published in: Trends in Cancer, Issue 7/9, 2021, Page(s) 847-862, ISSN 2405-8033
Publisher: Cell Press
DOI: 10.1016/j.trecan.2021.05.001

Technological challenges of biomembrane-coated top-down cancer nanotherapy

Author(s): João MJM Ravasco, Ana Cláudia Paiva-Santos, João Conde
Published in: Nature Reviews Bioengineering, 2023, ISSN 2731-6092
Publisher: Nature
DOI: 10.1038/s44222-022-00008-2

Biopolymeric Coatings for Local Release of Therapeutics from Biomedical Implants

Author(s): Sepehr Talebian, Bárbara Mendes, João Conniot, Syamak Farajikhah, Fariba Dehghani, Zhongyan Li, Diogo Bitoque, Gabriela Silva, Sina Naficy, João Conde, Gordon G Wallace
Published in: Advanced Science, 2023, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202207603

Gold nanoconjugates for miRNA modulation in cancer therapy: from miRNA silencing to miRNA mimics

Author(s): Diana P. Sousa and João Conde*
Published in: ACS materials, Issue 26942461, 2022, ISSN 2694-2461
Publisher: ACS Publications
DOI: 10.1021/acsmaterialsau.2c00042

Biomimetic cancer cell membrane-coated nanosystems as next-generation cancer therapies

Author(s): Miguel Pereira-Silva, Ana Cláudia Santos, João Conde, Clare Hoskins, Angel Concheiro, Carmen Alvarez-Lorenzo, Francisco Veiga
Published in: Expert Opinion on Drug Delivery, Issue 17/11, 2020, Page(s) 1515-1518, ISSN 1742-5247
Publisher: Ashley Publications Ltd.
DOI: 10.1080/17425247.2020.1813109

Ultrahigh Penetration and Retention of Graphene Quantum Dot Mesoporous Silica Nanohybrids for Image Guided Tumor Regression

Author(s): Rajendra Prasad, Nishant K. Jain, Amit S. Yadav, Manali Jadhav, Nalukurthi Naga Venkata Radharani, Mahadeo Gorain, Gopal C. Kundu, João Conde, Rohit Srivastava
Published in: ACS Applied Bio Materials, Issue 4/2, 2021, Page(s) 1693-1703, ISSN 2576-6422
Publisher: ACS Applied Bio Materials
DOI: 10.1021/acsabm.0c01478

CRISPR Systems for COVID-19 Diagnosis

Author(s): Hossein Rahimi, Marziyeh Salehiabar, Murat Barsbay, Mohammadreza Ghaffarlou, Taras Kavetskyy, Ali Sharafi, Soodabeh Davaran, Subhash C. Chauhan, Hossein Danafar, Saeed Kaboli, Hamed Nosrati, Murali M. Yallapu, João Conde
Published in: ACS Sensors, Issue 6/4, 2021, Page(s) 1430-1445, ISSN 2379-3694
Publisher: ACS Sensors
DOI: 10.1021/acssensors.0c02312

A large-scale machine learning analysis of inorganic nanoparticles in preclinical cancer research

Author(s): Bárbara B. Mendes, Zilu Zhang, João Conniot, Diana P. Sousa, João M. J. M. Ravasco, Lauren A. Onweller, Andżelika Lorenc, Tiago Rodrigues, Daniel Reker, João Conde
Published in: Nature Nanotechnology, Issue 19, 2024, Page(s) 867-878, ISSN 1748-3387
Publisher: Nature Publishing Group
DOI: 10.1038/s41565-024-01673-7

Using gold nanobeacons as a theranostic technique to recognize, detect, and inhibit specific nucleic acids

Author(s): D. P. Sousa, J. Conde
Published in: STAR Protocols, 2022, ISSN 2666-1667
Publisher: Cell Press
DOI: 10.1016/j.xpro.2022.101916

Engineering nanomaterials for glioblastoma nanovaccination

Author(s): Fatima Hameedat, Bárbara B. Mendes, João Conniot, Leonardo D. Di Filippo, Marlus Chorilli, Avi Schroeder, João Conde, Flávia Sousa
Published in: Nature Reviews Materials, Issue 9, 2024, Page(s) 628-642, ISSN 2058-8437
Publisher: Nature
DOI: 10.1038/s41578-024-00684-z

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

Author(s): Austin E Schumacher, Hmwe Hmwe Kyu, Amirali Aali, Cristiana Abbafati, Jaffar Abbas, Rouzbeh Abbasgholizadeh, Madineh Akram Abbasi, Mohammadreza Abbasian, Samar Abd ElHafeez, Michael Abdelmasseh, Sherief Abd-Elsalam, Ahmed Abdelwahab, Mohammad Abdollahi, Meriem Abdoun, Auwal Abdullahi, Ame Mehadi Abdurehman, Mesfin Abebe, Aidin Abedi, Armita Abedi, Tadesse M Abegaz, Roberto Ariel Abeldaño Zuñiga,
Published in: The Lancet, Issue 403, 2024, Page(s) 1989-2056, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(24)00476-8

Facts and Figures on Materials Science and Nanotechnology Progress and Investment

Author(s): Sepehr Talebian, Tiago Rodrigues, José das Neves, Bruno Sarmento, Robert Langer, João Conde
Published in: ACS Nano, 2021, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.1c03992

Burden of non-communicable diseases among adolescents aged 10-24 years in the EU, 1990-2019: a systematic analysis of the Global Burden of Diseases Study 2019

Author(s): Benedetta Armocida 1, Lorenzo Monasta 2, Susan Sawyer 3, Flavia Bustreo 4, Giulia Segafredo 5, Giulio Castelpietra 6, Luca Ronfani 7, Maja Pasovic 8, Simon Hay 8, GBD 2019 Europe NCDs in Adolescents Collaborators; Pablo Perel 9, David Beran 10
Published in: ancet Child Adolesc Health, Issue 23524650, 2022, ISSN 2352-4650
Publisher: Elsevier
DOI: 10.1016/s2352-4642(22)00073-6

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Author(s): Jaimie D Steinmetz, Katrin Maria Seeher, Nicoline Schiess, Emma Nichols, Bochen Cao, Chiara Servili, Vanessa Cavallera, Ewerton Cousin, Hailey Hagins, Madeline E Moberg, Max L Mehlman, Yohannes Habtegiorgis Abate, Jaffar Abbas, Madineh Akram Abbasi, Mohammadreza Abbasian, Hedayat Abbastabar, Michael Abdelmasseh, Mohammad Abdollahi, Mozhan Abdollahi, Mohammad-Amin Abdollahifar, Rami Abd-Rabu, Delda
Published in: The Lancet Neurology, Issue 23, 2024, Page(s) 344-381, ISSN 1474-4422
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1474-4422(24)00038-3

Machine learning for next-generation nanotechnology in healthcare

Author(s): Andzelika Lorenc; Andzelika Lorenc; Bárbara B. Mendes; João Conniot; Diana P. Sousa; João Conde; Tiago Rodrigues
Published in: Matter, Issue 25902385, 2021, ISSN 2590-2385
Publisher: Elsevier
DOI: 10.1016/j.matt.2021.09.014

Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression

Author(s): JoaoConde,◬RuthA.Pumroy,◬CharlotteBaker,◬TiagoRodrigues,◬AnaGuerreiro, BárbaraB.Sousa,MartaC.Marques,BernardoP.deAlmeida,SohyonLee,ElviraP.Leites, DanielPicard,AmritaSamanta,SandraH.Vaz,FlorianSieglitz,MaikeLangini,MarcRemke, RafaelRoque,TobiasWeiss,MichaelWeller,YuhangLiu,SeungilHan,FranciscoCorzana, VanessaA.Morais,CláudiaC.Faria,TaniaCarvalho,PanagisFilippakopoulos,BerendSnijder, Nuno
Published in: ACS central science, Issue 23747951, 2021, ISSN 2374-7951
Publisher: ACS Publications
DOI: 10.1021/acscentsci.1c00070

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Author(s): Mohsen Naghavi, Kanyin Liane Ong, Amirali Aali, Hazim S Ababneh, Yohannes Habtegiorgis Abate, Cristiana Abbafati, Rouzbeh Abbasgholizadeh, Mohammadreza Abbasian, Mohsen Abbasi-Kangevari, Hedayat Abbastabar, Samar Abd ElHafeez, Michael Abdelmasseh, Sherief Abd-Elsalam, Ahmed Abdelwahab, Mohammad Abdollahi, Mohammad-Amin Abdollahifar, Meriem Abdoun, Deldar Morad Abdulah, Auwal Abdullahi, Mesfin Abeb
Published in: The Lancet, Issue 403, 2024, Page(s) 2100-2132, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(24)00367-2

Prodrug Polymeric Nanoconjugates Encapsulating Gold Nanoparticles for Enhanced X-Ray Radiation Therapy in Breast Cancer

Author(s): Hamed Nosrati 1 2, Farzad Seidi 1, Ali Hosseinmirzaei 2, Navid Mousazadeh 2, Ali Mohammadi 2, Mohammadreza Ghaffarlou 3, Hossein Danafar 2, João Conde 4 5, Ali Sharafi 2
Published in: Adv Healthc Mater, Issue 21922659, 2022, ISSN 2192-2659
Publisher: World Scientific
DOI: 10.1002/adhm.202102321

Exosome membrane-coated nanosystems: Exploring biomedical applications in cancer diagnosis and therapy

Author(s): Minmin Shao, Daniela Lopes, Joana Lopes, Satar Yousefiasl, Ana Macário-Soares, Diana Peixoto, Inês Ferreira-Faria, Francisco Veiga, João Conde, Yi Huang, Xianfeng Chen, Ana Cláudia Paiva-Santos, Pooyan Makvandi
Published in: Matter, 2023, ISSN 2590-2385
Publisher: Cell Press
DOI: 10.1016/j.matt.2023.01.012

Preclinical assessment of an antibiotic-free cationic surfactant-based cellulose hydrogel for sexually and perinatally transmitted infections

Author(s): Rita D.A. Calado, Bárbara B. Mendes, João Conniot, João M.J.M. Ravasco, Daniel Sobral, Carolina Ferreira, Rita Ferreira, João Carlos Rodrigues, Daniela Santos, Sílvia Duarte, Luís Vieira, Ângela S. Inácio, Henrique Carrêlo, Winchil L.C. Vaz, João Paulo Gomes, Alexandra Nunes, João Conde, Otilia V. Vieira
Published in: Matter, Issue 7, 2024, Page(s) 2205-2235, ISSN 2590-2385
Publisher: Cell Press
DOI: 10.1016/j.matt.2024.04.002

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Author(s): Michael Brauer, Gregory A Roth, Aleksandr Y Aravkin, Peng Zheng, Kalkidan Hassen Abate, Yohannes Habtegiorgis Abate, Cristiana Abbafati, Rouzbeh Abbasgholizadeh, Madineh Akram Abbasi, Mohammadreza Abbasian, Mitra Abbasifard, Mohsen Abbasi-Kangevari, Samar Abd ElHafeez, Sherief Abd-Elsalam, Parsa Abdi, Mohammad Abdollahi, Meriem Abdoun, Deldar Morad Abdulah, Auwal Abdullahi, Mesfin Abebe, Aidin Abe
Published in: The Lancet, Issue 403, 2024, Page(s) 2162-2203, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(24)00933-4

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Author(s): Alize J Ferrari, Damian Francesco Santomauro, Amirali Aali, Yohannes Habtegiorgis Abate, Cristiana Abbafati, Hedayat Abbastabar, Samar Abd ElHafeez, Michael Abdelmasseh, Sherief Abd-Elsalam, Arash Abdollahi, Auwal Abdullahi, Kedir Hussein Abegaz, Roberto Ariel Abeldaño Zuñiga, Richard Gyan Aboagye, Hassan Abolhassani, Lucas Guimarães Abreu, Hasan Abualruz, Eman Abu-Gharbieh, Niveen ME Abu-Rmeil
Published in: The Lancet, Issue 403, 2024, Page(s) 2133-2161, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(24)00757-8

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