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Cancer heterogeneity and therapy profiling using bioresponsive nanohydrogels for the delivery of multicolor logic genetic circuits.

Project description

A nanoparticle platform for tumour profiling

Recent years have witnessed a significant increase in the use of nanomaterials for cancer theranostics. However, the physiological barriers of the tumour microenvironment (TME) alongside tumour heterogeneity pose major limitations to treatment and therapy. Scientists of the EU-funded GelGeneCircuit project propose to investigate how tumours respond to therapy as well as the underlying factors for the observed heterogeneity. To achieve this, they will develop a hydrogel-based platform for the delivery of nanoparticles that will assist in tumour profiling. Using this approach, they aim to identify novel biological targets and dissect key molecular mechanisms that will prove useful for the design of effective anti-cancer strategies.

Host institution

UNIVERSIDADE NOVA DE LISBOA
Net EU contribution
€ 1 435 312,00
Address
Campus De Campolide
1099 085 Lisboa
Portugal

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Region
Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Beneficiaries (2)

UNIVERSIDADE NOVA DE LISBOA
Portugal
Net EU contribution
€ 1 435 312,00
Address
Campus De Campolide
1099 085 Lisboa

See on map

Region
Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES

Participation ended

Portugal
Net EU contribution
€ 0,00
Address
Avenida Prof Egas Moniz
1649 028 Lisboa

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Region
Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa
Activity type
Research Organisations
Non-EU contribution
€ 0,00