Signaling dynamics in the control of cell proliferation and differentiation during development and homeostasis

Project Information

SignalingDynamics

Grant agreement ID: 850554

DOI 10.3030/850554

EC signature date 7 October 2019

Start date 1 March 2020

End date 28 February 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 500 000,00

EU contribution € 1 500 000,00

Coordinated by

KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data management plan

"The data management plan will provide data on how we will address the following points: ""1. Making data Findable, 2. Making data openly Accessible, 3. Making data Interoperable, 4. Increase data Re-use, 5. Allocation of resources and data security"" "

Publications

Peer reviewed articles (8)

From signalling oscillations to somite formation

Author(s): Wilke H.M. Meijer, Katharina F. Sonnen
Published in: Current Opinion in Systems Biology, Issue 39, 2024, Page(s) 100520, ISSN 2452-3100
Publisher: Current Opinion in Systems Biology
DOI: 10.1016/j.coisb.2024.100520

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking

Author(s): Yasmine el Azhar, Pascal Schulthess, Marek J. van Oostrom, Sonja D. C. Weterings, Wilke H. M. Meijer, Nobuko Tsuchida-Straeten, Wouter M. Thomas, Marianne Bauer, Katharina F. Sonnen
Published in: Development, 2024, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.202936

Building bridges between fields: bringing together development and homeostasis

Author(s): Sonja D. C. Weterings, Marek J. van Oostrom, Katharina F. Sonnen
Published in: Development, Issue 148/14, 2021, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.193268

Deciphering lineage specification during early embryogenesis in mouse gastruloids using multilayered proteomics

Author(s): Suzan Stelloo, Maria Teresa Alejo-Vinogradova, Charlotte A.G.H. van Gelder, Dick W. Zijlmans, Marek J. van Oostrom, Juan Manuel Valverde, Lieke A. Lamers, Teja Rus, Paula Sobrevals Alcaraz, Tilman Schäfers, Cristina Furlan, Pascal W.T.C. Jansen, Marijke P.A. Baltissen, Katharina F. Sonnen, Boudewijn Burgering, Maarten A.F.M. Altelaar, Harmjan R. Vos, Michiel Vermeulen
Published in: Cell Stem Cell, Issue 31, 2024, Page(s) 1072-1090.e8, ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2024.04.017

Signalling dynamics in embryonic development

Author(s): Katharina F. Sonnen, Claudia Y. Janda
Published in: Biochemical Journal, Issue 478, 2021, Page(s) 4045-4070, ISSN 0264-6021
Publisher: Portland Press, Ltd.
DOI: 10.1042/bcj20210043

Development in a Dish—In Vitro Models of Mammalian Embryonic Development

Author(s): Yasmine el Azhar, Katharina F. Sonnen
Published in: Frontiers in Cell and Developmental Biology, Issue 9, 2021, ISSN 2296-634X
Publisher: Frontiers
DOI: 10.3389/fcell.2021.655993

Bioengineering in vitro models of embryonic development

Author(s): Ananya Gupta, Matthias P. Lutolf, Alex J. Hughes, Katharina F. Sonnen
Published in: Stem Cell Reports, Issue 16/5, 2021, Page(s) 1104-1116, ISSN 2213-6711
Publisher: Cell Press
DOI: 10.1016/j.stemcr.2021.04.005

A Microfluidics Approach for the Functional Investigation of Signaling Oscillations Governing Somitogenesis

Author(s): Marek J. van Oostrom, Wilke H. M. Meijer, Katharina F. Sonnen
Published in: Journal of Visualized Experiments, Issue 169, 2021, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/62318

Other (1)

NOTCH-driven oscillations control cell fate decisions during intestinal homeostasis

Author(s): Sonja D. C. Weterings, Hiromune Eto, Jan-Daniël de Leede, Amir Giladi, Mirjam E. Hoekstra, Wouter F. Beijk, Esther J. M. Liefting, Karen B. van den Anker, Jacco van Rheenen, Alexander van Oudenaarden, Katharina F. Sonnen
Published in: BioRxiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.08.26.609553

Book chapters (1)

Signaling oscillations in embryonic development

Author(s): Sabine L.Bosman, Katharina F.Sonnen
Published in: Current Topics in Developmental Biology, 2022
Publisher: Elsevier
DOI: 10.1016/bs.ctdb.2022.02.011