Metabolic Imaging with RF Antennas to predict Chemotherapy Efficacy

Project description

An imaging approach that can predict chemotherapy efficacy

Being able to predict the response of patients to chemotherapy would undoubtedly be beneficial for patient well-being, avoiding the unnecessary toxic side effects. The metabolites phosphoethanolamine (PE) and glycerophosphocholine (GPC) are involved in cell membrane metabolism, and the PE to GPC ratio goes up during malignant transformation of cells. The EU-funded MIRACLE project aims to validate this ratio as a biomarker of predicting cancer treatment response. Scientists will assess these phospholipid biomarkers in patients in a non-invasive manner using MRI under different field strengths. The results of the study have the potential to bring the approach a step closer to regulatory clearance for clinical use.

Fields of science

• medical and health sciences › clinical medicine › surgery
• medical and health sciences › clinical medicine › radiology
• medical and health sciences › clinical medicine › oncology › breast cancer

Programme(s)

• H2020-EU.1.2.1. - FET Open

Topic(s)

• FETOPEN-03-2018-2019-2020 - FET Innovation Launchpad

Call for proposal

H2020-FETOPEN-2018-2019-2020-03
See other projects for this call

Funding Scheme

CSA - Coordination and support action

Coordinator

UNIVERSITAIR MEDISCH CENTRUM UTRECHT

Address

Heidelberglaan 100
3584 CX Utrecht
Netherlands

Activity type

Higher or Secondary Education Establishments

Links

EU contribution

€ 18 750

Participants (2)

REGENTS OF UNIVERSITY OF MINNESOTA

United States

EU contribution

€ 18 750

Address

Oak Street Se 200 Mcnamara Alumni Center 450
55455 2070 Minneapolis Mn

Activity type

Higher or Secondary Education Establishments

Links

WAVETRONICA BV

Netherlands

EU contribution

€ 62 500

Address

Padualaan 8 Room Z109
3584 CH Utrecht

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

Links