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Metabolic Imaging with RF Antennas to predict Chemotherapy Efficacy

Project description

An imaging approach that can predict chemotherapy efficacy

Being able to predict the response of patients to chemotherapy would undoubtedly be beneficial for patient well-being, avoiding the unnecessary toxic side effects. The metabolites phosphoethanolamine (PE) and glycerophosphocholine (GPC) are involved in cell membrane metabolism, and the PE to GPC ratio goes up during malignant transformation of cells. The EU-funded MIRACLE project aims to validate this ratio as a biomarker of predicting cancer treatment response. Scientists will assess these phospholipid biomarkers in patients in a non-invasive manner using MRI under different field strengths. The results of the study have the potential to bring the approach a step closer to regulatory clearance for clinical use.

Call for proposal

H2020-FETOPEN-2018-2019-2020-03
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Coordinator

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Address
Heidelberglaan 100
3584 CX Utrecht
Netherlands

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Activity type
Higher or Secondary Education Establishments
EU contribution
€ 18 750

Participants (2)

REGENTS OF UNIVERSITY OF MINNESOTA
United States
EU contribution
€ 18 750
Address
Oak Street Se 200 Mcnamara Alumni Center 450
55455 2070 Minneapolis Mn

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Activity type
Higher or Secondary Education Establishments
WAVETRONICA BV
Netherlands
EU contribution
€ 62 500
Address
Padualaan 8 Room Z109
3584 CH Utrecht

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)