Probing the mysteries of sweet “on-off” switches of the human immune system: toward the development of novel glycomimetics against bacterial infections

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Molecular recognition of Escherichia coli R1-type core lipooligosaccharide by DC-SIGN

Autores: Ferran Nieto-Fabregat, Angela Marseglia, Michel Thépaut, Jean-Philippe Kleman, Massilia Abbas, Aline Le Roy, Christine Ebel, Meriem Maalej, Jean-Pierre Simorre, Cedric Laguri, Antonio Molinaro, Alba Silipo, Franck Fieschi, Roberta Marchetti
Publicado en: iScience, Edición 27, 2024, Página(s) 108792, ISSN 2589-0042
Editor: Cell Press
DOI: 10.1016/j.isci.2024.108792

Conformationally Constrained Sialyl Analogues as NewPotential Binders of h-CD22

Autores: Rosa Ester Forgione, Ferran Fabregat Nieto, Cristina Di Carluccio, Francesco Milanesi, Martina Fruscella,Francesco Papi, Cristina Nativi, Antonio Molinaro,Pasquale Palladino,Simona Scarano,Maria Minunni, Marco Montefiori, Monica Civera,Sara Sattin, Oscar Francesconi,Roberta Marchetti,* and Alba Silipo
Publicado en: ChemBioChem, 2022, ISSN 1439-7633
Editor: Wiley-VCH

Structure and properties of the exopolysaccharide isolated from Flavobacterium sp. Root935

Autores: Marta Tiemblo-Martín, Valeria Pistorio, Pia Saake, Lisa Mahdi, María Asunción Campanero-Rhodes, Rocco Di Girolamo, Cristina Di Carluccio, Roberta Marchetti, Antonio Molinaro, Dolores Solís, Alga Zuccaro, Alba Silipo
Publicado en: Carbohydrate Polymers, Edición 343, 2024, Página(s) 122433, ISSN 0144-8617
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.carbpol.2024.122433

Chemical Synthesis of Sialyl N-Glycans and Analysis of Their Recognition by Neuraminidase

Autores: Asuka Shirakawa,Dr. Yoshiyuki Manabe,Dr. Roberta Marchetti,Kumpei Yano,Seiji Masui,Prof. Alba Silipo,Prof. Antonio Molinaro,Prof. Koichi Fukase
Publicado en: Angewandte Chemie International Edition, 2021, ISSN 0570-0833
Editor: Wiley -VCH

Characterization of Natural and Synthetic Sialoglycans Targeting theHemagglutinin-Neuraminidase of Mumps Virus

Autores: Rosa Ester Forgione, Cristina Di Carluccio, Francesco Milanesi, Marie Kubota, Ferran Fabregat Nieto, Antonio Molinaro, Takao Hashiguchi, Oscar Francesconi, Roberta Marchetti* and Alba Silipo*
Publicado en: Frontiers in Chemistry, 2021, ISSN 2296-2646
Editor: Frontiers

Molecular recognition of sialoglycans by streptococcal Siglec-like adhesins: toward the shape of specific inhibitors

Autores: Cristina Di Carluccio; Rosa Ester Forgione; Andrea Bosso; Shinji Yokoyama; Yoshiyuki Manabe; Elio Pizzo; Antonio Molinaro; Antonio Molinaro; Koichi Fukase; Marco Fragai; Barbara A. Bensing; Roberta Marchetti; Alba Silipo
Publicado en: RSC Chemical Biology, Edición 1, 2021, ISSN 2633-0679
Editor: RSC
DOI: 10.1039/d1cb00173f

Computational toolbox for the analysis of protein–glycan interactions

Autores: Ferran Nieto-Fabregat, Maria Pia Lenza, Angela Marseglia, Cristina Di Carluccio, Antonio Molinaro, Alba Silipo, Roberta Marchetti
Publicado en: Beilstein Journal of Organic Chemistry, Edición 20, 2024, Página(s) 2084-2107, ISSN 1860-5397
Editor: Beilstein-Institut
DOI: 10.3762/bjoc.20.180

Gonococcal Mimitope Vaccine Candidate Forms a Beta-Hairpin Turn and Binds Hydrophobically to a Therapeutic Monoclonal Antibody

Autores: Peter T. Beernink, Cristina Di Carluccio, Roberta Marchetti, Linda Cerofolini, Sara Carillo, Alessandro Cangiano, Nathan Cowieson, Jonathan Bones, Antonio Molinaro, Luigi Paduano, Marco Fragai, Benjamin P. Beernink, Sunita Gulati, Jutamas Shaughnessy, Peter A. Rice, Sanjay Ram, Alba Silipo
Publicado en: JACS Au, Edición 4, 2024, Página(s) 2617-2629, ISSN 2691-3704
Editor: American Chemical Society
DOI: 10.1021/jacsau.4c00359

Atomic-Level Dissection of DC-SIGN Recognition of Bacteroides vulgatus LPS Epitopes

Autores: Ferran Nieto-Fabregat, Qian Zhu, Corinne Vivès, Yunqin Zhang, Angela Marseglia, Fabrizio Chiodo, Michel Thépaut, Diksha Rai, Suvarn S. Kulkarni, Flaviana Di Lorenzo, Antonio Molinaro, Roberta Marchetti, Franck Fieschi, Guozhi Xiao, Biao Yu, Alba Silipo
Publicado en: JACS Au, Edición 4, 2024, Página(s) 697-712, ISSN 2691-3704
Editor: American Chemical Society
DOI: 10.1021/jacsau.3c00748

Liquid-state NMR spectroscopy for complex carbohydrate structuralanalysis: A hitchhiker's guide

Autores: ImmacolataSpeciale, AnnaNotaro, PilarGarcia-Vello, FlavianaDi Lorenzo, SamanthaArmiento, AntonioMolinaro, RobertaMarchetti, AlbaSilipo, CristinaDe Castro
Publicado en: Carbohydrate Polymers, 2021, ISSN 0144-8617
Editor: Pergamon Press Ltd.

Solving the structural puzzle of bacterial glycome

Autores: Roberta Marchetti, Rosa Ester Forgione, Ferran Nieto Fabregat, Cristina Di Carluccio, Antonio Molinaro, Alba Silipo
Publicado en: Current Opinion in Structural Biology, Edición 68, 2021, Página(s) 74-83, ISSN 0959-440X
Editor: Elsevier BV
DOI: 10.1016/j.sbi.2020.12.003

Tumor Carbohydrate Associated Antigen Analogs as Potential Binders for Siglec‐7

Autores: Cristina Di Carluccio, Francesco Milanesi, Monica Civera, Celeste Abreu, Sara Sattin, Oscar Francesconi, Antonio Molinaro, Ondřej Vaněk, Roberta Marchetti, Alba Silipo
Publicado en: European Journal of Organic Chemistry, Edición 26, 2024, ISSN 1434-193X
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.202300644

Molecular Insights into O-Linked Sialoglycans Recognition by the Siglec-Like SLBR-N (SLBRUB10712) of Streptococcus gordonii

Autores: Cristina Di Carluccio, Linda Cerofolini, Miguel Moreira, Frédéric Rosu, Luis Padilla-Cortés, Giulia Roxana Gheorghita, Zhuojia Xu, Abhishek Santra, Hai Yu, Shinji Yokoyama, Taylor E. Gray, Chris D. St. Laurent, Yoshiyuki Manabe, Xi Chen, Koichi Fukase, Matthew S. Macauley, Antonio Molinaro, Tiehai Li, Barbara A. Bensing, Roberta Marchetti, Valérie Gabelica, Marco Fragai, Alba Silipo
Publicado en: ACS Central Science, Edición 10, 2024, Página(s) 447-459, ISSN 2374-7943
Editor: ACS publications
DOI: 10.1021/acscentsci.3c01598

Exploring the Molecular Interactions of Symmetrical andUnsymmetrical Selenoglycosides with Human Galectin-1and Galectin-3

Autores: Luciano Pirone, Ferran Nieto-Fabregat, Sonia Di Gaetano , Domenica Capasso, Rita Russo, Serena Traboni, Antonio Molinaro, Alfonso Iadonisi, Michele Saviano, Roberta Marchetti, Alba Silipo, Emilia Pedone
Publicado en: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23158273

Expanding Knowledge of Methylotrophic Capacity: Structure andProperties of the Rough-Type Lipopolysaccharide fromMethylobacterium extorquens and Its Role on Membrane Resistanceto Methanol

Autores: Flaviana Di Lorenzo, Simone Nicolardi, Roberta Marchetti, Adele Vanacore, Noemi Gallucci, Katarzyna Duda, Ferran Nieto Fabregat, Ha Ngoc Anh Nguyen, Djamel Gully, James Saenz, Eric Giraud, Luigi Paduano, Antonio Molinaro, Gerardino D’Errico, Alba Silipo
Publicado en: JACS Au, 2023, ISSN 2691-3704
Editor: American Chemical Society
DOI: 10.1021/jacsau.3c00025

Role of EPS in mitigation of plant abiotic stress: The case ofMethylobacterium extorquens PA1

Autores: AdeleVanacore, Maria ConcettaForgione, DomenicoCavasso, Ha Ngoc, Anh Nguyen, Antonio Molinaro, James P.Saenz, GerardinoD'Errico, LuigiPaduano, Roberta Marchetti, Alba Silipo
Publicado en: Carbohydrate polymers, 2022, ISSN 1879-1344
Editor: Elsevier Ltd

Siglec-7 Mediates Immunomodulation by Colorectal Cancer-Associated Fusobacterium nucleatum ssp. animalis

Autores: Dimitra Lamprinaki, Pilar Garcia-Vello, Roberta Marchetti, Charlotte Hellmich, Kelli A. McCord, Kristian M. Bowles, Matthew S. Macauley, Alba Silipo , Cristina De Castro, Paul R. Crocker and Nathalie Juge
Publicado en: Frontiers in Immunology, 2021, ISSN 1664-3224
Editor: Frontiers

Antibody Recognition of Different Staphylococcus aureus Wall Teichoic Acid Glycoforms

Autores: Cristina Di Carluccio, Pablo Soriano Maldonado, Francesca Berni, Carla J. C. de Haas, A. Robin Temming, Astrid Hendriks, Sara Ali, Antonio Molinaro, Alba Silipo, Nina M. van Sorge, Mark J. van Raaij, Jeroen D. C. Codee, Roberta Marchetti
Publicado en: ACS central science, 2022, ISSN 2374-7943
Editor: ACS Publications

The unique 3D arrangement of macrophage galactose lectin enables Escherichia coli lipopolysaccharide recognition through two distinct interfaces

Autores: Massilia Abbas, Meriem Maalej, Ferran Nieto-Fabregat, Michel Thépaut, Jean-Philippe Kleman, Isabel Ayala, Antonio Molinaro, Jean-Pierre Simorre, Roberta Marchetti, Franck Fieschi, Cedric Laguri
Publicado en: PNAS Nexus, Edición 2, 2023, ISSN 2752-6542
Editor: PNAS Nexus
DOI: 10.1093/pnasnexus/pgad310

Molecular basis of bacterial lectin recognition of eukaryotic glycans: The case of Mycoplasma pneumoniae and Mycoplasma genitalium cytoadhesins

Autores: Angela Marseglia, Maria Concetta Forgione, Marina Marcos-Silva, Cristina Di Carluccio, Yoshiyuki Manabe, David Vizarraga, Ferran Nieto-Fabregat, Maria Pia Lenza, Koichi Fukase, Antonio Molinaro, Oscar Q. Pich, David Aparicio, Alba Silipo, Roberta Marchetti
Publicado en: International Journal of Biological Macromolecules, Edición 279, 2024, Página(s) 135277, ISSN 0141-8130
Editor: Elsevier BV
DOI: 10.1016/j.ijbiomac.2024.135277

Behavior of glycolylated sialoglycans in the bindingpockets of murine and human CD22

Autores: CristinaDi Carluccio, Rosa EsterForgione, MarcoMontefiori, MonicaCivera, SaraSattin, GiovanniSmaldone, K.Fukase, Y.Manabe, Paul R.Crocker, AntonioMolinaro, RobertaMarchetti, AlbaSilipo
Publicado en: iScience, 2021, ISSN 2589-0042
Editor: Elsevier

Semisynthetic Isomers of Fucosylated Chondroitin Sulfate Polysaccharides with Fucosyl Branches at a Non-Natural Site

Autores: Giulia Vessella; Roberta Marchetti; Angela Del Prete; Serena Traboni; Alfonso Iadonisi; Chiara Schiraldi; Alba Silipo; Emiliano Bedini
Publicado en: Biomacromolecules, Edición 2, 2021, ISSN 1526-4602
Editor: ACS
DOI: 10.1021/acs.biomac.1c01112

Unveiling Molecular Recognition of Sialoglycans by Human Siglec-10

Autores: Rosa Ester Forgione; Cristina Di Carluccio; Juan Guzmán-Caldentey; Rosa Gaglione; Filomena Battista; Fabrizio Chiodo; Yoshiyuki Manabe; Angela Arciello; Pompea Del Vecchio; Koichi Fukase; Antonio Molinaro; Sonsoles Martín-Santamaría; Paul R. Crocker; Roberta Marchetti; Alba Silipo
Publicado en: iScience, Vol 23, Iss 8, Pp 101401- (2020), Edición 1, 2020, ISSN 2589-0042
Editor: Cell Press
DOI: 10.1016/j.isci.2020.101231

Investigation of protein-ligand complexes by ligand-based NMR methods

Autores: Cristina Di Carluccio, Maria Concetta Forgione, Silvia Martini, Francesco Berti, Antonio Molinaro, Roberta Marchetti, Alba Silipo
Publicado en: Carbohydrate Research, 2021, ISSN 0008-6215
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.carres.2021.108313

Lipopolysaccharide O-antigen molecular and supramolecular modifications of plant root microbiota are pivotal for host recognition

Autores: Adele Vanacore; Giuseppe Vitiello; Alan Wanke; Domenico Cavasso; Luke A. Clifton; Lisa K. Mahdi; María Asunción Campanero-Rhodes; Dolores Solís; Manfred Wuhrer; Simone Nicolardi; Antonio Molinaro; Roberta Marchetti; Alga Zuccaro; Luigi Paduano; Alba Silipo
Publicado en: Carbohydrate Polymers, Edición 2, 2021, ISSN 0144-8617
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.carbpol.2021.118839

Total Synthesis of the Zwitterionic Trisaccharide Repeating Unit of Fusobacterium nucleatum ATCC 51191 O-antigen

Autores: Aishwarya Shelke, Amar Kumar Mishra, Bhaswati Ghosh, Roberta Marchetti, Alba Silipo, Suvarn Kulkarni
Publicado en: 2024
Editor: American Chemical Society (ACS)
DOI: 10.26434/chemrxiv-2024-xplqh

Buscando datos de OpenAIRE...

Publicaciones

Compartir esta página

Descargar