Deconstructing and rebuilding the evolution of cell and tissue mechanoadaptation

Project Information

CoEvolve

Grant agreement ID: 851960

DOI

10.3030/851960

Project closed

EC signature date 7 October 2019

Start date 1 January 2020

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 601,00

EU contribution

€ 1 499 601,00

Coordinated by

TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (19)

Spatial regulation of substrate adhesion directs fibroblast morphotype and phenotype

Author(s): Mirko D’Urso, Ignasi Jorba, Atze van der Pol, Carlijn V C Bouten, Nicholas A Kurniawan
Published in: PNAS Nexus, Issue 3, 2024, Page(s) pgae289, ISSN 2752-6542
Publisher: Oxford University Press
DOI: 10.1093/pnasnexus/pgae289

Human pluripotent stem cell-derived cardiomyocytes align under cyclic strain when guided by cardiac fibroblasts

Author(s): Dylan Mostert, Bart Groenen, Leda Klouda, Robert Passier, Marie-Jose Goumans, Nicholas A. Kurniawan, Carlijn V.C Bouten
Published in: APL Bioengineering, Issue 6, 2024, Page(s) 046108, ISSN 2473-2877
Publisher: AIP Publishing
DOI: 10.1101/2021.02.16.431369

Mechanical and Physical Regulation of Fibroblast–Myofibroblast Transition: From Cellular Mechanoresponse to Tissue Pathology

Author(s): Mirko D'Urso, Nicholas A. Kurniawan
Published in: Frontiers in Bioengineering and Biotechnology, Issue 8, 2020, Page(s) 609653, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2020.609653

Molecular packing structure of fibrin fibers resolved by X-ray scattering and molecular modeling

Author(s): Karin A. Jansen, Artem Zhmurov, Bart E. Vos, Giuseppe Portale, Daniel Hermida-Merino, Rustem I. Litvinov, Valerie Tutwiler, Nicholas A. Kurniawan, Wim Bras, John W. Weisel, Valeri Barsegov, Gijsje H. Koenderink
Published in: Soft Matter, Issue 16/35, 2020, Page(s) 8272-8283, ISSN 1744-683X
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0sm00916d

Cellular Contact Guidance Emerges from Gap Avoidance

Author(s): Antonetta B.C. Buskermolen, Tommaso Ristori, Dylan Mostert, Mark C. van Turnhout, Siamak S. Shishvan, Sandra Loerakker, Nicholas A. Kurniawan, Vikram S. Deshpande, Carlijn V.C. Bouten
Published in: Cell Reports Physical Science, Issue 1/5, 2020, Page(s) 100055, ISSN 2666-3864
Publisher: Cell Press
DOI: 10.1016/j.xcrp.2020.100055

In-vitro engineered human cerebral tissues mimic pathological circuit disturbances in 3D

Author(s): Aref Saberi, Albert P. Aldenkamp, Nicholas A. Kurniawan, Carlijn V. C. Bouten
Published in: Communications Biology, Issue 5, 2022, Page(s) 254, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-022-03203-4

A multi-cue bioreactor to evaluate the inflammatory and regenerative capacity of biomaterials under flow and stretch

Author(s): Suzanne E. Koch, Eline E. van Haaften, Tamar B. Wissing, Lizzy A. B. Cuypers, Jurgen A. Bulsink, Carlijn V. C. Bouten, Nicholas A. Kurniawan, Anthal I. P. M. Smits
Published in: Journal of Visualized Experiments, Issue 166, 2020, Page(s) e61824, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/61824

Protein Micropatterning in 2.5D: An Approach to Investigate Cellular Responses in Multi-Cue Environments

Author(s): Cas van der Putten, Antonetta B. C. Buskermolen, Maike Werner, Hannah F. M. Brouwer, Paul A. A. Bartels, Patricia Y. W. Dankers, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Published in: ACS Applied Materials & Interfaces, Issue 13/22, 2021, Page(s) 25589-25598, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.1c01984

Methacrylated human recombinant collagen peptide as a hydrogel for manipulating and monitoring stiffness-related cardiac cell behavior

Author(s): Dylan Mostert, Ignasi Jorba, Bart G.W. Groenen, Robert Passier, Marie-José T.H. Goumans, Huibert A. van Boxtel, Nicholas A. Kurniawan, Carlijn V.C. Bouten, Leda Klouda
Published in: iScience, Issue 26, 2025, Page(s) 106423, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2023.106423

<i>In Vitro</i>Methods to Model Cardiac Mechanobiology in Health and Disease

Author(s): Ignasi Jorba, Dylan Mostert, Leon H.L. Hermans, Atze van der Pol, Nicholas A. Kurniawan, Carlijn V.C. Bouten
Published in: Tissue Engineering Part C: Methods, Issue 27, 2023, Page(s) 139-151, ISSN 1937-3384
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tec.2020.0342

Stimuli-responsive materials: A smart way to study dynamic cell responses

Author(s): Maaike Bril, Sebastian Fredrich, Nicholas A. Kurniawan
Published in: Smart Materials in Medicine, Issue 3, 2022, Page(s) 257-273, ISSN 2590-1834
Publisher: Elsevier
DOI: 10.1016/j.smaim.2022.01.010

Shape‐Morphing Photoresponsive Hydrogels Reveal Dynamic Topographical Conditioning of Fibroblasts

Author(s): Maaike Bril, Aref Saberi, Ignasi Jorba, Mark C. van Turnhout, Cecilia M. Sahlgren, Carlijn V.C. Bouten, Albert P.H.J. Schenning, Nicholas A. Kurniawan
Published in: Advanced Science, Issue 10, 2023, Page(s) 2303136, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202303136

SFAlab: image-based quantification of mechano-active ventral actin stress fibers in adherent cells

Author(s): Dylan Mostert, Janine Grolleman, Mark C. van Turnhout, Bart G. W. Groenen, Vito Conte, Cecilia M. Sahlgren, Nicholas A. Kurniawan, Carlijn V. C. Bouten
Published in: Frontiers in Cell and Developmental Biology, Issue 11, 2023, Page(s) 1267822, ISSN 2296-634X
Publisher: Frontier Media
DOI: 10.3389/fcell.2023.1267822

Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue

Author(s): Eline E. van Haaften, Sjeng Quicken, Wouter Huberts, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Published in: Communications Biology, Issue 4, 2021, Page(s) 546, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-021-02065-6

Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales

Author(s): Barbara Schamberger, Ricardo Ziege, Karine Anselme, Martine Ben Amar, Michał Bykowski, André P. G. Castro, Amaia Cipitria, Rhoslyn A. Coles, Rumiana Dimova, Michaela Eder, Sebastian Ehrig, Luis M. Escudero, Myfanwy E. Evans, Paulo R. Fernandes, Peter Fratzl, Liesbet Geris, Notburga Gierlinger, Edouard Hannezo, Aleš Iglič, Jacob J. K. Kirkensgaard, Philip Kollmannsberger, Łucja Kowalewska, Nic
Published in: Advanced Materials, Issue 35, 2024, Page(s) 2206110, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202206110

Myofibroblast transdifferentiation of keratocytes results in slower migration and lower sensitivity to mesoscale curvatures

Author(s): Cas van der Putten, Daniëlle van den Broek, Nicholas A. Kurniawan
Published in: Frontiers in Cell and Developmental Biology, Issue 10, 2022, Page(s) 930373, ISSN 2296-634X
Publisher: Frontiers Media
DOI: 10.3389/fcell.2022.930373

3D Interfacial and Spatiotemporal Regulation of Human Neuroepithelial Organoids

Author(s): Chunling Tang, Xinhui Wang, Mirko D'Urso, Cas van der Putten, Nicholas A. Kurniawan
Published in: Advanced Science, Issue 2022, 2022, Page(s) 2201106, ISSN 2219-7478
Publisher: Wiley
DOI: 10.1002/advs.202201106

Generation of Multicue Cellular Microenvironments by UV-photopatterning of Three-dimensional Cell Culture Substrates

Author(s): Cas van der Putten, Mirko D'Urso, Maaike Bril, Thomas E. Woud, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Published in: Journal of Visualized Experiments, Issue 184, 2022, Page(s) e63988, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/63988

Dimensionality Matters: Exploiting UV-Photopatterned 2D and Two-Photon-Printed 2.5D Contact Guidance Cues to Control Corneal Fibroblast Behavior and Collagen Deposition

Author(s): Cas van der Putten, Gozde Sahin, Rhiannon Grant, Mirko D’Urso, Stefan Giselbrecht, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Published in: Bioengineering, Issue 11, 2025, Page(s) 402, ISSN 2306-5354
Publisher: MDPI
DOI: 10.3390/bioengineering11040402