Deconstructing and rebuilding the evolution of cell and tissue mechanoadaptation

Informazioni relative al progetto

CoEvolve

ID dell’accordo di sovvenzione: 851960

DOI

10.3030/851960

Progetto chiuso

Data della firma CE 7 Ottobre 2019

Data di avvio 1 Gennaio 2020

Data di completamento 31 Dicembre 2024

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 499 601,00

Contributo UE

€ 1 499 601,00

Coordinato da

TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (19)

Spatial regulation of substrate adhesion directs fibroblast morphotype and phenotype

Autori: Mirko D’Urso, Ignasi Jorba, Atze van der Pol, Carlijn V C Bouten, Nicholas A Kurniawan
Pubblicato in: PNAS Nexus, Numero 3, 2024, Pagina/e pgae289, ISSN 2752-6542
Editore: Oxford University Press
DOI: 10.1093/pnasnexus/pgae289

Human pluripotent stem cell-derived cardiomyocytes align under cyclic strain when guided by cardiac fibroblasts

Autori: Dylan Mostert, Bart Groenen, Leda Klouda, Robert Passier, Marie-Jose Goumans, Nicholas A. Kurniawan, Carlijn V.C Bouten
Pubblicato in: APL Bioengineering, Numero 6, 2024, Pagina/e 046108, ISSN 2473-2877
Editore: AIP Publishing
DOI: 10.1101/2021.02.16.431369

Mechanical and Physical Regulation of Fibroblast–Myofibroblast Transition: From Cellular Mechanoresponse to Tissue Pathology

Autori: Mirko D'Urso, Nicholas A. Kurniawan
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 8, 2020, Pagina/e 609653, ISSN 2296-4185
Editore: Frontiers
DOI: 10.3389/fbioe.2020.609653

Molecular packing structure of fibrin fibers resolved by X-ray scattering and molecular modeling

Autori: Karin A. Jansen, Artem Zhmurov, Bart E. Vos, Giuseppe Portale, Daniel Hermida-Merino, Rustem I. Litvinov, Valerie Tutwiler, Nicholas A. Kurniawan, Wim Bras, John W. Weisel, Valeri Barsegov, Gijsje H. Koenderink
Pubblicato in: Soft Matter, Numero 16/35, 2020, Pagina/e 8272-8283, ISSN 1744-683X
Editore: Royal Society of Chemistry
DOI: 10.1039/d0sm00916d

Cellular Contact Guidance Emerges from Gap Avoidance

Autori: Antonetta B.C. Buskermolen, Tommaso Ristori, Dylan Mostert, Mark C. van Turnhout, Siamak S. Shishvan, Sandra Loerakker, Nicholas A. Kurniawan, Vikram S. Deshpande, Carlijn V.C. Bouten
Pubblicato in: Cell Reports Physical Science, Numero 1/5, 2020, Pagina/e 100055, ISSN 2666-3864
Editore: Cell Press
DOI: 10.1016/j.xcrp.2020.100055

In-vitro engineered human cerebral tissues mimic pathological circuit disturbances in 3D

Autori: Aref Saberi, Albert P. Aldenkamp, Nicholas A. Kurniawan, Carlijn V. C. Bouten
Pubblicato in: Communications Biology, Numero 5, 2022, Pagina/e 254, ISSN 2399-3642
Editore: Springer Nature
DOI: 10.1038/s42003-022-03203-4

A multi-cue bioreactor to evaluate the inflammatory and regenerative capacity of biomaterials under flow and stretch

Autori: Suzanne E. Koch, Eline E. van Haaften, Tamar B. Wissing, Lizzy A. B. Cuypers, Jurgen A. Bulsink, Carlijn V. C. Bouten, Nicholas A. Kurniawan, Anthal I. P. M. Smits
Pubblicato in: Journal of Visualized Experiments, Numero 166, 2020, Pagina/e e61824, ISSN 1940-087X
Editore: MYJoVE Corporation
DOI: 10.3791/61824

Protein Micropatterning in 2.5D: An Approach to Investigate Cellular Responses in Multi-Cue Environments

Autori: Cas van der Putten, Antonetta B. C. Buskermolen, Maike Werner, Hannah F. M. Brouwer, Paul A. A. Bartels, Patricia Y. W. Dankers, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Pubblicato in: ACS Applied Materials & Interfaces, Numero 13/22, 2021, Pagina/e 25589-25598, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.1c01984

Methacrylated human recombinant collagen peptide as a hydrogel for manipulating and monitoring stiffness-related cardiac cell behavior

Autori: Dylan Mostert, Ignasi Jorba, Bart G.W. Groenen, Robert Passier, Marie-José T.H. Goumans, Huibert A. van Boxtel, Nicholas A. Kurniawan, Carlijn V.C. Bouten, Leda Klouda
Pubblicato in: iScience, Numero 26, 2025, Pagina/e 106423, ISSN 2589-0042
Editore: Cell Press
DOI: 10.1016/j.isci.2023.106423

<i>In Vitro</i>Methods to Model Cardiac Mechanobiology in Health and Disease

Autori: Ignasi Jorba, Dylan Mostert, Leon H.L. Hermans, Atze van der Pol, Nicholas A. Kurniawan, Carlijn V.C. Bouten
Pubblicato in: Tissue Engineering Part C: Methods, Numero 27, 2023, Pagina/e 139-151, ISSN 1937-3384
Editore: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tec.2020.0342

Stimuli-responsive materials: A smart way to study dynamic cell responses

Autori: Maaike Bril, Sebastian Fredrich, Nicholas A. Kurniawan
Pubblicato in: Smart Materials in Medicine, Numero 3, 2022, Pagina/e 257-273, ISSN 2590-1834
Editore: Elsevier
DOI: 10.1016/j.smaim.2022.01.010

Shape‐Morphing Photoresponsive Hydrogels Reveal Dynamic Topographical Conditioning of Fibroblasts

Autori: Maaike Bril, Aref Saberi, Ignasi Jorba, Mark C. van Turnhout, Cecilia M. Sahlgren, Carlijn V.C. Bouten, Albert P.H.J. Schenning, Nicholas A. Kurniawan
Pubblicato in: Advanced Science, Numero 10, 2023, Pagina/e 2303136, ISSN 2198-3844
Editore: Wiley
DOI: 10.1002/advs.202303136

SFAlab: image-based quantification of mechano-active ventral actin stress fibers in adherent cells

Autori: Dylan Mostert, Janine Grolleman, Mark C. van Turnhout, Bart G. W. Groenen, Vito Conte, Cecilia M. Sahlgren, Nicholas A. Kurniawan, Carlijn V. C. Bouten
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 11, 2023, Pagina/e 1267822, ISSN 2296-634X
Editore: Frontier Media
DOI: 10.3389/fcell.2023.1267822

Computationally guided in-vitro vascular growth model reveals causal link between flow oscillations and disorganized neotissue

Autori: Eline E. van Haaften, Sjeng Quicken, Wouter Huberts, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Pubblicato in: Communications Biology, Numero 4, 2021, Pagina/e 546, ISSN 2399-3642
Editore: Springer Nature
DOI: 10.1038/s42003-021-02065-6

Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales

Autori: Barbara Schamberger, Ricardo Ziege, Karine Anselme, Martine Ben Amar, Michał Bykowski, André P. G. Castro, Amaia Cipitria, Rhoslyn A. Coles, Rumiana Dimova, Michaela Eder, Sebastian Ehrig, Luis M. Escudero, Myfanwy E. Evans, Paulo R. Fernandes, Peter Fratzl, Liesbet Geris, Notburga Gierlinger, Edouard Hannezo, Aleš Iglič, Jacob J. K. Kirkensgaard, Philip Kollmannsberger, Łucja Kowalewska, Nic
Pubblicato in: Advanced Materials, Numero 35, 2024, Pagina/e 2206110, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202206110

Myofibroblast transdifferentiation of keratocytes results in slower migration and lower sensitivity to mesoscale curvatures

Autori: Cas van der Putten, Daniëlle van den Broek, Nicholas A. Kurniawan
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 10, 2022, Pagina/e 930373, ISSN 2296-634X
Editore: Frontiers Media
DOI: 10.3389/fcell.2022.930373

3D Interfacial and Spatiotemporal Regulation of Human Neuroepithelial Organoids

Autori: Chunling Tang, Xinhui Wang, Mirko D'Urso, Cas van der Putten, Nicholas A. Kurniawan
Pubblicato in: Advanced Science, Numero 2022, 2022, Pagina/e 2201106, ISSN 2219-7478
Editore: Wiley
DOI: 10.1002/advs.202201106

Generation of Multicue Cellular Microenvironments by UV-photopatterning of Three-dimensional Cell Culture Substrates

Autori: Cas van der Putten, Mirko D'Urso, Maaike Bril, Thomas E. Woud, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Pubblicato in: Journal of Visualized Experiments, Numero 184, 2022, Pagina/e e63988, ISSN 1940-087X
Editore: MYJoVE Corporation
DOI: 10.3791/63988

Dimensionality Matters: Exploiting UV-Photopatterned 2D and Two-Photon-Printed 2.5D Contact Guidance Cues to Control Corneal Fibroblast Behavior and Collagen Deposition

Autori: Cas van der Putten, Gozde Sahin, Rhiannon Grant, Mirko D’Urso, Stefan Giselbrecht, Carlijn V. C. Bouten, Nicholas A. Kurniawan
Pubblicato in: Bioengineering, Numero 11, 2025, Pagina/e 402, ISSN 2306-5354
Editore: MDPI
DOI: 10.3390/bioengineering11040402